Tumor-specific expression of shVEGF and suicide gene as a novel strategy for esophageal cancer therapy.

abstract：BACKGROUND:Aberrant expression of stanniocalcin 2 (STC2) is implicated in colon adenocarcinoma (COAD). A previous study identified that STC2 functions as a tumor promoter to drive development of some cancers, but the role of its overexpression in the development of COAD remains unclear. AIM:To evaluate the regulation ...

journal_title：World journal of gastroenterology

authors： Li JB,Liu ZX,Zhang R,Ma SP,Lin T,Li YX,Yang SH,Zhang WC,Wang YP

更新日期：2019-06-14 00:00:00

abstract：:The scientific framework concerning estrogen effects on different tissues has expanded enormously during the last decades, when estrogen receptor (ER) subtypes were identified. Estrogens are not only essential for the female reproductive system, but they also control fundamental functions in other tissues including th...

journal_title：World journal of gastroenterology

authors： Alvaro D,Mancino MG,Onori P,Franchitto A,Alpini G,Francis H,Glaser S,Gaudio E

更新日期：2006-06-14 00:00:00

abstract：BACKGROUND:In recent decades, an increasing number of patients have received minimally invasive intervention for infected pancreatic necrosis (IPN) because of the benefits in reducing postoperative multiple organ failure and mortality. However, there are limited published data regarding infection recurrence after treat...

journal_title：World journal of gastroenterology

authors： Gao CC,Li J,Cao F,Wang XH,Li A,Wang Z,Li F

更新日期：2020-06-14 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this article, we describe the clinical course of a patient who developed a pancreatic recurrence of RCC and 1 yea...

journal_title：World journal of gastroenterology

authors： Riviello C,Tanini I,Cipriani G,Pantaleo P,Nozzoli C,Poma A,Riccardo V,Valeri A

更新日期：2006-08-28 00:00:00

abstract：:Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insufficiency of perfusion, is a common mechanism for tissue death or degeneration, and at a lower threshold, a mechanism for the generation of sensory signallin...

journal_title：World journal of gastroenterology

authors： Hoff DA,Gregersen H,Hatlebakk JG

更新日期：2009-01-14 00:00:00

abstract：AIM:To study the inhibitory effect of mononuclear bone marrow cell (BMC) transplantation on carbon tetrachloride (CCl(4)) -induced liver fibrosis in rats. METHODS:Rat liver fibrosis models were induced by CCl(4) and alcohol administration. After 8 wk, twenty rats were randomly allocated into treatment group (n = 10) a...

journal_title：World journal of gastroenterology

authors： Cao BQ,Lin JZ,Zhong YS,Huang SB,Lin N,Tang ZF,Chen R,Xiang P,Xu RY

更新日期：2007-03-28 00:00:00

abstract：AIM:To investigate the therapeutic effects of recombinant human growth hormone (rhGH) on rat septic shock with intraabdominal infection by E. coli and its possible mechanism. METHODS:76 SD rats were divided into 3 groups randomly: control group (group C, n=16) without any special treatment, septic shock group (group S...

journal_title：World journal of gastroenterology

authors： Huang Y,Wang SR,Yi C,Ying MY,Lin Y,Zhi MH

更新日期：2002-12-01 00:00:00

abstract：AIM:To investigate the effect of Jianweiyuyang (JWYY) granule on gastric ulcer recurrence and its mechanism in the treatment of gastric ulcer in rats. METHODS:Gastric ulcer in rats was induced according to Okeba's method with minor modification and the recurrence model was induced by IL-1beta. The expression of vascul...

journal_title：World journal of gastroenterology

authors： Dai XP,Li JB,Liu ZQ,Ding X,Huang CH,Zhou B

更新日期：2005-09-21 00:00:00

abstract：:Colorectal cancer (CRC) is one of the commonest cancers with 1.2 million new cases diagnosed each year in the world. It remains the fourth most common cause of cancer-related mortality in the world and accounts for > 600000 cancer-related deaths each year. There have been significant advances in treatment of metastati...

journal_title：World journal of gastroenterology

authors： Khan K,Wale A,Brown G,Chau I

更新日期：2014-09-21 00:00:00

abstract：:Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy. Although many cases resolve spontaneously, some lead to chronic symptoms including diarrhea, tenesmus, urgency and persistent rectal bleeding with iron deficiency anemia requiring blood transfusions. Treatments for chronic radiat...

journal_title：World journal of gastroenterology

authors： Rustagi T,Mashimo H

更新日期：2011-11-07 00:00:00

abstract：AIM:To evaluate the role of RARalpha gene in mediating the growth inhibitory effect of all-trans retinoic acid (ATRA) on gastric cancer cells. METHODS:The expression levels of retinoic acid receptors (RARs) in gastric cancer cells were detected by Northern blot. Transient transfection and chlorophenicol acetyl transfe...

journal_title：World journal of gastroenterology

authors： Liu S,Wu Q,Chen ZM,Su WJ

更新日期：2001-10-01 00:00:00

abstract：AIM:To prospectively explore the role of carcinoembryonic antigen (CEA) in gallbladder bile in patients with colorectal carcinoma and the morphological and clinical features of neoplasia and the occurrence of hepatic metastases. METHODS:CEA levels in the gallbladder and peripheral blood were studied in 44 patients wit...

journal_title：World journal of gastroenterology

authors： Waisberg J,Palma RT,Neto LC,Martins LC,Oliveira MS,Nagashima CA,Godoy AC,Goffi FS

更新日期：2003-07-01 00:00:00

abstract：AIM:To assess the outcomes of drug therapy (DT) followed by pancreatic endotherapy for continuing painful episodes in recurrent acute pancreatitis. METHODS:DT comprised of pancreatic enzymes and anti-oxidants failing which, endotherapy (ET; pancreatic sphincterotomy and stent placement) was done. The frequency of pain...

journal_title：World journal of gastroenterology

authors： Pai CG,Kamath MG,Shetty MV,Kurien A

更新日期：2017-05-21 00:00:00

abstract：AIM:To investigate the efficacy and potential mechanism of Xiaotan Tongfu granules (XTTF) in stress ulcers. METHODS:One hundred sixty rats were randomly divided into 4 groups (n = 10) as follows: the model group (MP group), the control group (CP group), the ranitidine group (RP group) and the XTTF granule group (XP gr...

journal_title：World journal of gastroenterology

authors： Yan B,Shi J,Xiu LJ,Liu X,Zhou YQ,Feng SH,Lv C,Yuan XX,Zhang YC,Li YJ,Wei PK,Qin ZF

更新日期：2013-09-07 00:00:00

abstract：AIM:To investigate the antioxidative status of patients with alcoholic liver disease (ALD) in southeastern Taiwan. METHODS:Our study comprised 27 patients with ALD recruited from Taitung Mackay Memorial Hospital, located in southeastern Taiwan. Patients with ALD included 12 non-aborigines (12 men) and 15 aborigines (1...

journal_title：World journal of gastroenterology

authors： Chen YL,Chen LJ,Bair MJ,Yao ML,Peng HC,Yang SS,Yang SC

更新日期：2011-02-28 00:00:00

abstract：AIM:To explore the cooperative effects of antisense oligonucleotide (ASON) of cell adhesion molecules and cimetidine on the expression of E-selectin and ICAM-1 in endothelial cells and their adhesion to tumor cells. METHODS:After treatment of endothelial cells with ASON and/or cimetidine and induction with TNF-alpha, ...

journal_title：World journal of gastroenterology

authors： Tang NH,Chen YL,Wang XQ,Li XJ,Yin FZ,Wang XZ

更新日期：2004-01-01 00:00:00

abstract：:Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (OGCs) is very rare, less than 1% of all pancreatic malignancies, and shows worse prognosis than that of invasive ductal adenocarcinoma of the pancreas. We present a case of en bloc resection for a huge undifferentiated carcinoma with OGCs tha...

journal_title：World journal of gastroenterology

authors： Jo S

更新日期：2014-03-14 00:00:00

abstract：AIM:To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines. METHODS:Gastric lesions were produced by oral gavage of aspirin (200 mg/kg) and HCl (0.15 mol/...

journal_title：World journal of gastroenterology

authors： Odashima M,Otaka M,Jin M,Komatsu K,Wada I,Horikawa Y,Matsuhashi T,Hatakeyama N,Oyake J,Ohba R,Watanabe S,Linden J

更新日期：2006-01-28 00:00:00

abstract：:Hereditary pancreatitis is an autosomal dominant condition, which results in recurrent attacks of acute pancreatitis, progressing to chronic pancreatitis often at a young age. The majority of patients with hereditary pancreatitis express one of two mutations (R122H or N29I) in the cationic trypsinogen gene (PRSS1 gene...

journal_title：World journal of gastroenterology

authors： Charnley RM

更新日期：2003-01-01 00:00:00

abstract：AIM:To determine the prevalence, characteristics and clinical course of pancreatic cystic neoplasms (PCNs) in liver transplantation (LT) recipients. METHODS:We retrospectively studied consecutive patients who underwent LT between January 1998 to April 2016. Clinical and laboratory data were obtained from patient medic...

journal_title：World journal of gastroenterology

authors： Liu K,Joshi V,van Camp L,Yang QW,Baars JE,Strasser SI,McCaughan GW,Majumdar A,Saxena P,Kaffes AJ

更新日期：2017-12-28 00:00:00

abstract：:Ingested fish bone induced intestinal perforations are seldom diagnosed preoperatively due to incomplete patient history taking and difficulties in image evidence identification. Most literature suggests early surgical intervention to prevent sepsis and complications resulting from fish bone migrations. We report the ...

journal_title：World journal of gastroenterology

authors： Kuo CC,Jen TK,Wen CH,Liu CP,Hsiao HS,Liu YC,Chen KH

更新日期：2012-11-07 00:00:00

abstract：:Pancreatic carcinomas with acinar differentiation are rare, accounting for 1%-2% of adult pancreatic tumors; they include pancreatic acinar cell carcinoma (PACC), pancreatoblastoma, and carcinomas of mixed differentiation. Patients with PACC have a prognosis better than pancreatic ductal adenocarcinomas but worse than...

journal_title：World journal of gastroenterology

authors： Al-Hader A,Al-Rohil RN,Han H,Von Hoff D

更新日期：2017-12-07 00:00:00

abstract：:Chronic pancreatitis (CP) continues to be a clinical challenge. Persistent or recurrent abdominal pain is the most compelling symptom that drives patients to seek medical care. Unfortunately, in spite of using several treatment approaches in the clinical setting, there is no single specific treatment modality that can...

journal_title：World journal of gastroenterology

authors： Talukdar R,Reddy DN

更新日期：2013-10-14 00:00:00

abstract：AIM:To study the protein C activation system in human liver myofibroblasts, and the effects of activated protein C (APC) on these cells. METHODS:Human liver myofibroblasts were obtained by outgrowth. Expression of protease activated receptor 1 (PAR-1), endothelial protein C receptor (EPCR) and thrombomodulin (TM) was ...

journal_title：World journal of gastroenterology

authors： Gillibert-Duplantier J,Rullier A,Neaud V,Kisiel W,Rosenbaum J

更新日期：2010-01-14 00:00:00

abstract：AIM:To investigate the expression and clinical significance of B7 homolog 3 (B7-H3) and β-1,3-galactosyltransferase-4 (B3GALT4) in colorectal cancer (CRC) patients. METHODS:Using tissue microarray, we identified the expression of B7-H3 and B3GALT4 in 223 CRC patient samples by immunohistochemistry and evaluated the po...

journal_title：World journal of gastroenterology

authors： Zhang T,Wang F,Wu JY,Qiu ZC,Wang Y,Liu F,Ge XS,Qi XW,Mao Y,Hua D

更新日期：2018-08-21 00:00:00

abstract：AIM:To assess the outcomes of ampulla dilation with different sized balloons to remove common bile duct (CBD) stones. METHODS:Patients (n = 208) were divided into five groups based on the largest CBD stone size of < 5, 6-8, 8-12, 12-14, and > 14 mm. Patients underwent limited endoscopic sphincterotomy (EST) alone or l...

journal_title：World journal of gastroenterology

authors： Li NP,Liu JQ,Zhou ZQ,Ji TY,Cai XY,Zhu QY

更新日期：2013-02-14 00:00:00

abstract：:A 46-year-old female patient with terminal ileum Crohn's disease and ankylosing spondylitis presented with recurrent angioedema and urticaria. Investigations ruled out hereditary angioedema, and environmental or food allergen triggers. She was diagnosed with chronic idiopathic urticaria with angioedema, and was treate...

journal_title：World journal of gastroenterology

authors： Habal F,Huang V

更新日期：2012-09-14 00:00:00

abstract：:Primary hepatic neuroendocrine tumor (PHNET) is an extremely rare liver tumor. Patients often have no clinical symptoms or have only non-specific symptoms, such as abdominal pain and abdominal mass. The clinical manifestations, disease development, treatment methods, and treatment outcomes of PHNET vary greatly among ...

journal_title：World journal of gastroenterology

authors： Meng XF,Pan YW,Wang ZB,Duan WD

更新日期：2018-06-28 00:00:00

abstract：:Recently, inflammatory bowel disease (IBD) has been the subject of considerable research, with increasing attention being paid to the loss of intestinal epithelial cell barrier function as a mechanism of pathogenesis. Ste20-related proline/alanine-rich kinase (SPAK) is involved in regulating barrier function. SPAK is ...

journal_title：World journal of gastroenterology

authors： Yan Y,Merlin D

更新日期：2008-10-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) produce an enzyme known as γ-glutamyl transpeptidase (HpGGT) that is highly conserved and common to all strains. HpGGT has been gaining increasing attention as an important virulence factor of the bacterium, having been demonstrated to be an important colonization factor in several anim...

journal_title：World journal of gastroenterology

authors： Ling SS,Yeoh KG,Ho B

更新日期：2013-12-07 00:00:00