Primary hepatic neuroendocrine tumor case with a preoperative course of 26 years: A case report and literature review.

abstract：AIM:To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS:The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flow cytometry and TUNEL...

journal_title：World journal of gastroenterology

authors： Lu CJ,He YF,Yuan WZ,Xiang LJ,Zhang J,Liang YR,Duan J,He YH,Li MY

更新日期：2017-09-14 00:00:00

abstract：AIM:To explore the mechanism for interactions of leptin with ghrelin and orexin in the arcuate nucleus (ARC) activating neuropeptide Y (NPY) neurons during physiological regulation of feeding. METHODS:Single neurons from ARC of adult rats with matured feeding function were isolated. [Ca2+]i was measured to monitor the...

journal_title：World journal of gastroenterology

authors： Kohno D,Suyama S,Yada T

更新日期：2008-11-07 00:00:00

abstract：:Irritable bowel syndrome (IBS) is an extremely prevalent but poorly understood gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help diagnose the disorder and treatment options are limited to management of the symptoms. The concept of a dysregulated gut-brain axis has been adopted as a...

journal_title：World journal of gastroenterology

authors： Kennedy PJ,Cryan JF,Dinan TG,Clarke G

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:Although previous studies have confirmed the feasibility of magnetic compression anastomosis (MCA), there is still a risk of long-term anastomotic stenosis. For traditional MCA devices, a large device is associated with great pressure, and eventually increased leakage. AIM:To develop a novel MCA device to s...

journal_title：World journal of gastroenterology

authors： Chen H,Ma T,Wang Y,Zhu HY,Feng Z,Wu RQ,Lv Y,Dong DH

更新日期：2020-11-14 00:00:00

abstract：:Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of virally infected cells in the liver is related to the HCV-induced inability of the immune system to reco...

journal_title：World journal of gastroenterology

authors： Osna NA

更新日期：2009-03-14 00:00:00

abstract：:While therapeutic strategies able to change the natural history of the disease are developing, it is of major importance to have available predictive factors for aggressive disease to try and target these therapeutic strategies. Clinical predictors have probably been the most broadly studied. In both Crohn's disease (...

journal_title：World journal of gastroenterology

authors： Louis E,Belaiche J,Reenaers C

更新日期：2010-06-07 00:00:00

abstract：:Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma (MM), it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that requires further evaluation. A 49-year-old man presented with acute renal failure and was diagnosed with ka...

journal_title：World journal of gastroenterology

authors： Rahhal FE,Schade RR,Nayak A,Coleman TA

更新日期：2009-04-28 00:00:00

abstract：AIM:To investigate the clinical efficacy and toxic effects of neoadjuvant chemotherapy using docetaxel combined with oxaliplatin and fluorouracil for treating stage III/IV gastric cancer. METHODS:A total of 53 stage III/IV gastric cancer patients were enrolled into the study and treated with neoadjuvant chemotherapy. ...

journal_title：World journal of gastroenterology

authors： Yu YJ,Sun WJ,Lu MD,Wang FH,Qi DS,Zhang Y,Li PH,Huang H,You T,Zheng ZQ

更新日期：2014-12-28 00:00:00

abstract：AIM:To evaluate the prophylactic efficacy of hepatitis B immunoglobulin (HBIG) in combination with different nucleos(t)ide analogues. METHODS:A total of 5333 hepatitis B surface antigen-positive patients from the China Liver Transplant Registry database were enrolled between January 2000 and December 2009. Low-dose in...

journal_title：World journal of gastroenterology

authors： Shen S,Jiang L,Xiao GQ,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Xu MQ,Wei YG

更新日期：2015-01-14 00:00:00

abstract：AIM:To investigate whether hypoxia inducible factor-1alpha (HIF-1alpha) is linked to the protective effects of ischemic preconditioning (IP) on sinusoidal endothelial cells against ischemia/reperfusion injury. METHODS:Sinusoidal endothelial cell lines ECV-304 were cultured and divided into four groups: control group, ...

journal_title：World journal of gastroenterology

authors： Shi LB,Huang JH,Han BS

更新日期：2007-04-28 00:00:00

abstract：AIM:To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC). METHODS:The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its p...

journal_title：World journal of gastroenterology

authors： Sun XD,Cai XY,Li JD,Cai XJ,Mu YP,Wu JM

更新日期：2003-04-01 00:00:00

abstract：:Cystic dystrophy of the duodenal wall is a rare form of the disease which was described in 1970 by French authors who reported the presence of focal pancreatic disease localized in an area comprising the C-loop of the duodenum and the head of the pancreas. German authors have defined this area as a "groove". We report...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Santini D,Calculli L,Casadei R,Morselli-Labate AM,Imbrogno A,Fabbri D,Taffurelli G,Ricci C,Corinaldesi R

更新日期：2011-10-21 00:00:00

abstract：AIM:To evaluate the efficacy and safety of capsule oxymatrine in the treatment of chronic hepatitis B. METHODS:A randomised double-blind and placebo-controlled multicenter trial was conducted. Injection of oxymatrine was used as positive-control drug. A total of 216 patients with chronic hepatitis B entered the study ...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Mao YM,Li JQ,Wan MB,Li CZ,Chen CW,Fu QC,Wang JY,She WM,Cai X,Ye J,Zhou XQ,Wang H,Wu SM,Tang MF,Zhu JS,Chen WX,Zhang HQ

更新日期：2003-11-01 00:00:00

abstract：AIM:To examine the effect of hepatitis C virus (HCV) structural mimics of regulatory regions of the genome on HCV replication. METHODS:HCV RNA structural mimics were constructed and tested in a HCV genotype 1b aBB7 replicon, and a Japanese fulminant hepatitis-1 (JFH-1) HCV genotype 2a infection model. All sequences we...

journal_title：World journal of gastroenterology

authors： Smolic R,Smolic M,Andorfer JH,Wu CH,Smith RM,Wu GY

更新日期：2010-05-07 00:00:00

abstract：AIM:To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer. METHODS:A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption an...

journal_title：World journal of gastroenterology

authors： Qian HG,Shen J,Ma H,Ma HC,Su YH,Hao CY,Xing BC,Huang XF,Shou CC

更新日期：2005-10-28 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a chronic condition affecting 3%-25% of the general population. As no curative treatment is available, therapy is aimed at reducing symptoms, often with little success. Because alteration of the normal intestinal microflora has been observed in IBS, probiotics (beneficial microbes tak...

journal_title：World journal of gastroenterology

authors： McFarland LV,Dublin S

更新日期：2008-05-07 00:00:00

abstract：:AIM:To determine whether recombinant human epidermal growth factor (rhEGF) can protect gastric mucosa against ethanol induced injury in rats.METHOD: Fifty-four SD rats weighing 200g-500g each were divided into six groups after fasting for 24 hours.Three groups received different doses of oral rhEGF (30, 60 and 120&mgr...

journal_title：World journal of gastroenterology

authors： Xu CD,Gan RB,Chen SN,Jiang SH,Xu JY

更新日期：1998-10-01 00:00:00

abstract：:Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions are well established biological events which have an important role in not just normal tissue and organ development, but in the pathogenesis of diseases. Increasing evidence has established their presence in the human colon during colorectal carcinoge...

journal_title：World journal of gastroenterology

authors： Sipos F,Galamb O

更新日期：2012-02-21 00:00:00

abstract：:The term "hemangioma" refers to the common tumor of infancy that exhibits rapid postnatal growth and slow regression during childhood. It may cause confusion with venous malformations that are often incorrectly called "cavernous hemangioma". Venous malformations comprise abnormally formed channels that are lined by qu...

journal_title：World journal of gastroenterology

authors： Fernandez-Pineda I

更新日期：2009-11-07 00:00:00

abstract：AIM:To investigate genetic factors that might help define which Crohn's disease (CD) patients are likely to benefit from anti-tumor necrosis factor (TNF) therapy. METHODS:This was a prospective cohort study. Patients were recruited from a university digestive disease practice database. We included CD patients who rece...

journal_title：World journal of gastroenterology

authors： Netz U,Carter JV,Eichenberger MR,Dryden GW,Pan J,Rai SN,Galandiuk S

更新日期：2017-07-21 00:00:00

abstract：:According to the main international clinical guidelines, the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. However, doubts have been raised about the appropriate definition of clinical complete response (cCR) after neoadjuvant therapy and the role of sur...

journal_title：World journal of gastroenterology

authors： López-Campos F,Martín-Martín M,Fornell-Pérez R,García-Pérez JC,Die-Trill J,Fuentes-Mateos R,López-Durán S,Domínguez-Rullán J,Ferreiro R,Riquelme-Oliveira A,Hervás-Morón A,Couñago F

更新日期：2020-08-07 00:00:00

abstract：:Hepatitis B virus (HBV) infection is still the most common cause of hepatocellular carcinoma and liver cirrhosis world wide. Recently, however, there has been quite dramatic improvement in the understanding of HBV associated liver disease and its treatment. It has become clear that high viral replication is a major ri...

journal_title：World journal of gastroenterology

authors： Tillmann HL

更新日期：2007-01-07 00:00:00

abstract：:In their seminal papers Hanahan and Weinberg described oncogenic processes a normal cell undergoes to be transformed into a cancer cell. The functions of ion channels in the gastrointestinal (GI) tract influence a variety of cellular processes, many of which overlap with these hallmarks of cancer. In this review we fo...

journal_title：World journal of gastroenterology

authors： Anderson KJ,Cormier RT,Scott PM

更新日期：2019-10-14 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A "multiple-hit" pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stre...

journal_title：World journal of gastroenterology

authors： Clemente MG,Mandato C,Poeta M,Vajro P

更新日期：2016-09-28 00:00:00

abstract：:AIM:It is well known that colonoscopy can be difficult due to abdominal pain induced during colonoscope insertion, if sedative agents are not given. Recently, an extra-flexible, small-diameter colonoscope (CF-SV, Olympus Inc.Japan) was developed in order to improve safety and comfort. The aim of this study was to acce...

journal_title：World journal of gastroenterology

authors： Han Y,Uno Y,Munakata A

更新日期：2000-10-01 00:00:00

abstract：AIM:To investigate the antioxidative status of patients with alcoholic liver disease (ALD) in southeastern Taiwan. METHODS:Our study comprised 27 patients with ALD recruited from Taitung Mackay Memorial Hospital, located in southeastern Taiwan. Patients with ALD included 12 non-aborigines (12 men) and 15 aborigines (1...

journal_title：World journal of gastroenterology

authors： Chen YL,Chen LJ,Bair MJ,Yao ML,Peng HC,Yang SS,Yang SC

更新日期：2011-02-28 00:00:00

abstract：:Based on reviews of the literature and experts' consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice. In addition to what has been covered in previously published guidelines on the management of cirrhosis complicatio...

journal_title：World journal of gastroenterology

authors： Xu XY,Ding HG,Li WG,Xu JH,Han Y,Jia JD,Wei L,Duan ZP,Ling-Hu EQ,Zhuang H

更新日期：2020-12-07 00:00:00

abstract：:Hypertriglyceridemic pancreatitis (HTGP) accounts for up to 10% of acute pancreatitis presentations in non-pregnant individuals and is the third most common cause of acute pancreatitis after alcohol and gallstones. There are a number of retrospective studies and case reports that have suggested a role for apheresis an...

journal_title：World journal of gastroenterology

authors： Saleh MA,Mansoor E,Cooper GS

更新日期：2017-10-28 00:00:00

abstract：AIM:To discuss the expression of human leukocyte antigen (HLA) class I antigens in gastric cancer and correlate these with pathologic type and TNM stage. METHODS:The expression of HLA class I antigen was detected by immunohistochemistry in 185 specimens of gastric cancer, 20 gastric cancer specimens with lymphatic met...

journal_title：World journal of gastroenterology

authors： Shen YQ,Zhang JQ,Miao FQ,Zhang JM,Jiang Q,Chen H,Shan XN,Xie W

更新日期：2005-06-21 00:00:00

abstract：:Ghrelin, as a kind of multifunctional protein polypeptide, is mainly produced in the fundus of the stomach and can promote occurrence and development of many tumors, including gastrointestinal tumors, which has been proved by the relevant researches. Most gastrointestinal stromal tumors (GISTs, about 80%), as the most...

journal_title：World journal of gastroenterology

authors： Zhu CZ,Liu D,Kang WM,Yu JC,Ma ZQ,Ye X,Li K

更新日期：2017-03-14 00:00:00