Hepatic failure caused by plasma cell infiltration in multiple myeloma.

abstract：:A 83-year-old woman was admitted to our hospital because of intermittent abdominal colicky pain and vomiting for 26 h. The pain localized over the periumbilical area with radiation along the medial side of the thigh. Computed tomography scan with three-dimensional reconstruction revealed a loop of small bowel protrudi...

journal_title：World journal of gastroenterology

authors： Zhang H,Cong JC,Chen CS

更新日期：2010-01-07 00:00:00

abstract：:Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast e...

journal_title：World journal of gastroenterology

authors： Ohkura Y,Hashimoto M,Lee S,Sasaki K,Matsuda M,Watanabe G

更新日期：2014-07-07 00:00:00

abstract：AIM:Trace elements (TE) metabolism is altered in inflammatory bowel diseases. TE (zinc and copper) are constituents of antioxidant enzymes. Iron is involved in the pathogenesis of chronic inflammation. The aim was to evaluate zinc and copper status and the effects of iron manipulation in experimental colitis. METHODS:...

journal_title：World journal of gastroenterology

authors： Barollo M,D'Inca R,Scarpa M,Medici V,Cardin R,Bortolami M,Ruffolo C,Angriman I,Sturniolo GC

更新日期：2005-07-28 00:00:00

abstract：AIM:Over 90% of drugs are metabolized by the cytochrome P-450 (CYP) family of liver isoenzymes. The most important enzymes are CYP1A2, 3A4, 2C9/19, 2D6 and 2E1. Although CYP2D6 accounts for <2% of the total CYP liver enzyme content, it mediates metabolism in almost 25% of drugs. In order to study its enzymatic activity...

journal_title：World journal of gastroenterology

authors： Zhuge J,Yu YN,Wu XD

更新日期：2004-01-15 00:00:00

abstract：:The liver is one of the most important organs in the body, performing a fundamental role in the regulation of diverse processes, among which the metabolism, secretion, storage, and detoxification of endogenous and exogenous substances are prominent. Due to these functions, hepatic diseases continue to be among the mai...

journal_title：World journal of gastroenterology

authors： Madrigal-Santillán E,Madrigal-Bujaidar E,Álvarez-González I,Sumaya-Martínez MT,Gutiérrez-Salinas J,Bautista M,Morales-González Á,García-Luna y González-Rubio M,Aguilar-Faisal JL,Morales-González JA

更新日期：2014-10-28 00:00:00

abstract：AIM:To explore the role of heat shock protein-90 (HSP-90) for nitrergic vasorelaxation in the splanchnic circulation in rats with and without portal hypertension. METHODS:Neuronal nitric oxide synthase (nNOS) and HSP-90 were analyzed by immunofluorescence, western blotting and co-immunoprecipitation in the mesenteric ...

journal_title：World journal of gastroenterology

authors： Moleda L,Jurzik L,Froh M,Gäbele E,Hellerbrand C,Straub RH,Schölmerich J,Wiest R

更新日期：2010-04-21 00:00:00

abstract：BACKGROUND:Small-for-size grafts (SFSGs) in living donor liver transplantation (LDLT) could optimize donor postoperative outcomes and also expand the potential donor pool. Evidence on whether SFSGs would affect medium-term and long-term recipient graft survival is lacking. AIM:To evaluate the impact of small-for-size ...

journal_title：World journal of gastroenterology

authors： Ma KW,Wong KHC,Chan ACY,Cheung TT,Dai WC,Fung JYY,She WH,Lo CM,Chok KSH

更新日期：2019-09-28 00:00:00

abstract：:It is reported that a pancreatic disease may precede the diagnosis of inflammatory bowel disease (IBD) both in children and in adults. Idiopathic chronic pancreatitis, however, occasionally co-exists with the IBD, mainly at pediatric age. We report a case of a patient who progressively developed the features of a chro...

journal_title：World journal of gastroenterology

authors： Knafelz D,Panetta F,Monti L,Bracci F,Papadatou B,Torre G,Dall'Oglio L,Diamanti A

更新日期：2013-08-21 00:00:00

abstract：AIM:Hepatocellular carcinoma (HCC) is a common disease in Taiwan. The prevalence of viral hepatitis infection and the subsequent development of HCC are well known to be higher in patients with end-stage renal disease (ESRD) requiring hemodialysis (HD) or peritoneal dialysis (PD) than among the general population. Howev...

journal_title：World journal of gastroenterology

authors： Yeh CN,Lee WC,Chen MF

更新日期：2005-04-14 00:00:00

abstract：AIM:To compare the effect of intravenous and oral omeprazole in patients with bleeding peptic ulcers without high-risk stigmata. METHODS:This randomized study included 211 patients [112 receiving iv omeprazole protocol (Group 1), 99 receiving po omeprazole 40 mg every 12 h (Group 2)] with a mean age of 52.7. In 144 pa...

journal_title：World journal of gastroenterology

authors： Yilmaz S,Bayan K,Tüzün Y,Dursun M,Canoruç F

更新日期：2006-12-28 00:00:00

abstract：:Liver cancers are the second most frequent cause of global cancer-related mortality of which 90% are attributable to hepatocellular carcinoma (HCC). Despite the advent of screening programmes for patients with known risk factors, a substantial number of patients are ineligible for curative surgery at presentation with...

journal_title：World journal of gastroenterology

authors： Inchingolo R,Posa A,Mariappan M,Spiliopoulos S

更新日期：2019-08-28 00:00:00

abstract：AIM:To investigate the effects of sodium alginate (AL-Na) on indomethacin-induced small intestinal lesions in rats. METHODS:Gastric injury was assessed by measuring ulcerated legions 4 h after indomethacin (25 mg/kg) administration. Small intestinal injury was assessed by measuring ulcerated legions 24 h after indomet...

journal_title：World journal of gastroenterology

authors： Yamamoto A,Itoh T,Nasu R,Nishida R

更新日期：2014-03-14 00:00:00

abstract：AIM:To investigate the predictive clinical value of in vitro 3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide (MTT) assay for directing chemosensitivity in patients with gastric cancer. METHODS:Results of a total of 353 consecutive patients with gastric cancer treated with MTT-directed chemotherapy or phys...

journal_title：World journal of gastroenterology

authors： Wu B,Zhu JS,Zhang Y,Shen WM,Zhang Q

更新日期：2008-05-21 00:00:00

abstract：:During the last decades, further knowledge of hepatocellular carcinoma (HCC) molecular mechanisms has led to development of effective systemic treatments including tyrosine kinase inhibitors (TKIs) and immunotherapy. In this review, we describe first and second line systemic treatment options for advanced HCC. Several...

journal_title：World journal of gastroenterology

authors： Piñero F,Silva M,Iavarone M

更新日期：2020-04-28 00:00:00

abstract：AIM:To compare molecular profiles of proximal colon, distal colon and rectum in large adenomas, early and late carcinomas. To assess feasibility of testing directed at molecular markers from this study in routine clinical practice. METHODS:A prospective 3-year study has resulted in the acquisition of samples from 159 ...

journal_title：World journal of gastroenterology

authors： Minarikova P,Benesova L,Halkova T,Belsanova B,Suchanek S,Cyrany J,Tuckova I,Bures J,Zavoral M,Minarik M

更新日期：2016-05-28 00:00:00

abstract：:Autoimmune hepatitis (AIH) is a rare chronic inflammatory disease of the liver, which affects a group of patients who lost their immunological tolerance to antigens of the liver. It is clinically characterized by hypergammaglobulinemia, elevated liver enzymes, presence of autoantibodies and histological changes. Altho...

journal_title：World journal of gastroenterology

authors： Ferri Liu PM,de Miranda DM,Fagundes ED,Ferreira AR,Simões e Silva AC

更新日期：2013-07-28 00:00:00

abstract：AIM:To assess whether juvenile chronic ferric iron ingestion limit colitis and dysbiosis at adulthood in rats and mice. METHODS:Two sets of experiments were designed. In the first set, recently weaned mice were either orally administered ferrous (Fe²⁺) iron salt or ferric (Fe³⁺) microencapsulated iron for 6 wk. The la...

journal_title：World journal of gastroenterology

authors： Ettreiki C,Gadonna-Widehem P,Mangin I,Coëffier M,Delayre-Orthez C,Anton PM

更新日期：2012-06-07 00:00:00

abstract：AIM:To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis. METHODS:Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 ...

journal_title：World journal of gastroenterology

authors： Letoha T,Fehér LZ,Pecze L,Somlai C,Varga I,Kaszaki J,Tóth G,Vizler C,Tiszlavicz L,Takács T

更新日期：2007-09-07 00:00:00

abstract：AIM:To elucidate the molecular mechanisms leading to development of functionally impaired dendritic cells (DCs) in chronic hepatitis C (CHC) patients infected with genotype 3 virus. METHODS:This prospective study was conducted on the cohorts of CHC individuals identified as responders or non-responders to antiviral th...

journal_title：World journal of gastroenterology

authors： Tomer S,Chawla YK,Duseja A,Arora SK

更新日期：2016-06-14 00:00:00

abstract：AIM:To explore a safe and efficient strategy of tumor therapy using anti-angiogenetic agents. METHODS:Endostatin gene with a signal sequence of human IgGgamma chain was amplified by PCR and cloned into pVAX1 plasmid which was the only vector authorized by FDA in clinical trial to construct a recombinant plasmid named ...

journal_title：World journal of gastroenterology

authors： Ma CH,Zhang Y,Wang XY,Gao LF,Liu H,Guo C,Liu SX,Cao YL,Zhang LN,Sun WS

更新日期：2004-10-01 00:00:00

abstract：AIM:To evaluate prospectively usefulness of fecal lactoferrin (Lf) and fecal hemoglobin (Hb) in the diagnosis of colorectal diseases. METHODS:Fecal Lf and Hb were measured using ELISA in 872 patients before they underwent colorectal endoscopy. RESULTS:Lf was positive in 18 (50%) of 36 patients with colorectal cancer,...

journal_title：World journal of gastroenterology

authors： Hirata I,Hoshimoto M,Saito O,Kayazawa M,Nishikawa T,Murano M,Toshina K,Wang FY,Matsuse R

更新日期：2007-03-14 00:00:00

abstract：AIM:To investigate the relationship between Helicobacter pylori (H. pylori) and mucin expression in gastric mucosa. METHODS:English Medical literature searches were conducted for gastric mucin expression in H. pylori infected people vs uninfected people. Searches were performed up to December 31(th) 2014, using MEDLIN...

journal_title：World journal of gastroenterology

authors： Niv Y

更新日期：2015-08-21 00:00:00

abstract：AIM:To evaluate the inhibition effect of HCV NS5A on p53 transactivation on p21 promoter and explore its possible mechanism for influencing p53 function. METHODS:p53 function of transactivation on p21 promoter was studied with a luciferase reporter system in which the luciferase gene is driven by p21 promoter, and the...

journal_title：World journal of gastroenterology

authors： Gong GZ,Jiang YF,He Y,Lai LY,Zhu YH,Su XS

更新日期：2004-08-01 00:00:00

abstract：AIM:To make a retrospective analysis of endoscopy findings and clinicopathologic characteristics of colonic schistosomiasis in order to further improve our understanding of the disease and decrease its misdiagnosis. METHODS:Endoscopy findings and clinicopathologic characteristics of 46 intestinal schistosomiasis patie...

journal_title：World journal of gastroenterology

authors： Cao J,Liu WJ,Xu XY,Zou XP

更新日期：2010-02-14 00:00:00

abstract：AIM:To show outcomes of our series of patients that underwent a total gastrectomy with a robotic approach and highlight the technical details of a proposed solution for the reconstruction phase. METHODS:Data of gastrectomies performed from May 2014 to October 2016, were extracted and analyzed. Basic characteristics of...

journal_title：World journal of gastroenterology

authors： Parisi A,Ricci F,Gemini A,Trastulli S,Cirocchi R,Palazzini G,D'Andrea V,Desiderio J

更新日期：2017-06-21 00:00:00

abstract：AIM:To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice. METHODS:Balb/c mice were fed with the fermented milk for 7 d after inducing gastritis with acetyl-salicylic acid (ASA, 400 m...

journal_title：World journal of gastroenterology

authors： Rodríguez C,Medici M,Mozzi F,Font de Valdez G

更新日期：2010-04-07 00:00:00

abstract：BACKGROUND:At our academic tertiary care medical center, we have noted patients referred for endoscopic retrograde cholangiopancreatography (ERCP) who increasingly require advanced cannulation techniques. This trend is noted despite increased endoscopist experience and annual ERCP volume over the same period. AIM:To e...

journal_title：World journal of gastroenterology

authors： Barakat MT,Girotra M,Thosani N,Kothari S,Banerjee S

更新日期：2020-11-07 00:00:00

abstract：AIM:To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines. METHODS:Gastric lesions were produced by oral gavage of aspirin (200 mg/kg) and HCl (0.15 mol/...

journal_title：World journal of gastroenterology

authors： Odashima M,Otaka M,Jin M,Komatsu K,Wada I,Horikawa Y,Matsuhashi T,Hatakeyama N,Oyake J,Ohba R,Watanabe S,Linden J

更新日期：2006-01-28 00:00:00

abstract：AIM:To evaluate the effectiveness and safety of different portal vein branch embolization agents in inducing compensatory hypertrophy of the remnant liver and to offer a theoretic basis for clinical portal vein branch embolization. METHODS:Forty-one adult dogs were included in the experiment and divided into four grou...

journal_title：World journal of gastroenterology

authors： Huang JY,Yang WZ,Li JJ,Jiang N,Zheng QB

更新日期：2006-01-21 00:00:00

abstract：AIM:To investigate the association of tumor necrosis factor alpha (TNFα) -G308A polymorphism with different liver pathological changes in treatment-naïve Egyptian patients infected with hepatitis C virus (HCV) genotype 4. METHODS:This study included 180 subjects, composed of 120 treatment-naïve chronic HCV patients wi...

journal_title：World journal of gastroenterology

authors： Bader El Din NG,Farouk S,El-Shenawy R,Ibrahim MK,Dawood RM,Elhady MM,Salem AM,Zayed N,Khairy A,El Awady MK

更新日期：2016-09-14 00:00:00