Irritable bowel syndrome: a microbiome-gut-brain axis disorder?

abstract：:Neuroendocrine carcinoma (NEC) of the gallbladder is a rare subtype of gallbladder tumor. Here, we report two cases of NEC in two patients initially suspected to have gallbladder carcinoma. No specific symptoms or abnormal blood test results were observed preoperatively. Abdominal computed tomography scans indicated i...

journal_title：World journal of gastroenterology

authors： Chen H,Shen YY,Ni XZ

更新日期：2014-09-07 00:00:00

abstract：:Primary hepatic neuroendocrine carcinoma (NEC) with concurrent occurrence of hepatocellular carcinoma (HCC) of the liver is very rare. Only 8 cases have been reported in the literature. Concurrent occurrence of HCC and NEC in the liver is classified as combined type or collision type by histological distributional pat...

journal_title：World journal of gastroenterology

authors： Choi GH,Ann SY,Lee SI,Kim SB,Song IH

更新日期：2016-11-07 00:00:00

abstract：AIM:To investigate and characterise patients with chronic hepatitis C virus (HCV) infection presenting with hepatocellular carcinoma (HCC) in the absence of cirrhosis. METHODS:Patients with chronic hepatitis C infection without cirrhosis presenting with HCC over a 2-year period were identified. The clinical case notes...

journal_title：World journal of gastroenterology

authors： Nash KL,Woodall T,Brown AS,Davies SE,Alexander GJ

更新日期：2010-08-28 00:00:00

abstract：AIM:To evaluate the predictive value of preoperative predictors for portal vein thrombosis (PVT) after splenectomy with periesophagogastric devascularization. METHODS:In this prospective study, 69 continuous patients with portal hypertension caused by hepatitis B cirrhosis underwent splenectomy with periesophagogastri...

journal_title：World journal of gastroenterology

authors： Zhang Y,Wen TF,Yan LN,Yang HJ,Deng XF,Li C,Wang C,Liang GL

更新日期：2012-04-21 00:00:00

abstract：AIM:To identify the scFv antibody fragments specific for hepatocellular carcinoma by biopanning from a large human naive scFv phage display library. METHODS:A large human naive scFv phage library was used to search for the specific targets by biopanning with the hepatocellular carcinoma cell line HepG2 for the positiv...

journal_title：World journal of gastroenterology

authors： Yu B,Ni M,Li WH,Lei P,Xing W,Xiao DW,Huang Y,Tang ZJ,Zhu HF,Shen GX

更新日期：2005-07-14 00:00:00

abstract：AIM:To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury. METHODS:Wistar male rats underwent partial liver ischemia performed by clamping the pedicle from the medium and left anterior lateral segments for 1 h under mechanical ventilation. They were divided into 3 groups: Control G...

journal_title：World journal of gastroenterology

authors： Nogueira MA,Coelho AM,Sampietre SN,Patzina RA,Pinheiro da Silva F,D'Albuquerque LA,Machado MC

更新日期：2014-11-07 00:00:00

abstract：:Ghrelin, as a kind of multifunctional protein polypeptide, is mainly produced in the fundus of the stomach and can promote occurrence and development of many tumors, including gastrointestinal tumors, which has been proved by the relevant researches. Most gastrointestinal stromal tumors (GISTs, about 80%), as the most...

journal_title：World journal of gastroenterology

authors： Zhu CZ,Liu D,Kang WM,Yu JC,Ma ZQ,Ye X,Li K

更新日期：2017-03-14 00:00:00

abstract：:Left ventricular assist devices (LVAD) are increasingly become common as life prolonging therapy in patients with advanced heart failure. Current devices are now used as definitive treatment in some patients given the improved durability of continuous flow pumps. Unfortunately, continuous flow LVADs are fraught with c...

journal_title：World journal of gastroenterology

authors： Vedachalam S,Balasubramanian G,Haas GJ,Krishna SG

更新日期：2020-05-28 00:00:00

abstract：AIM:To explore the correlation between expression of somatostatin (SS), gastrin (GAS) and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma. METHODS:Sixty-two large intestine cancer tissue samples were randomly and retrospectively selected from patients with large intestine carcinoma. Immunohistoch...

journal_title：World journal of gastroenterology

authors： Mao JD,Wu P,Xia XH,Hu JQ,Huang WB,Xu GQ

更新日期：2005-02-07 00:00:00

abstract：AIM:To assess the risk of relapse in ulcerative colitis (UC) patients in clinical remission using mucosal status and fecal immunochemical test (FIT) results. METHODS:The clinical outcomes of 194 UC patients in clinical remission who underwent colonoscopy were based on evaluations of Mayo endoscopic subscores (MESs) an...

journal_title：World journal of gastroenterology

authors： Nakarai A,Kato J,Hiraoka S,Takashima S,Takei D,Inokuchi T,Sugihara Y,Takahara M,Harada K,Okada H

更新日期：2016-06-07 00:00:00

abstract：AIM:To compare the clinical outcomes between jejunal interposition reconstruction and Roux-en-Y anastomosis after total gastrostomy in patients with gastric cancer. METHODS:A systematic literature search was conducted by two independent researchers on PubMed, EMBASE, the Cochrane Library, Google Scholar, and other Eng...

journal_title：World journal of gastroenterology

authors： Fan KX,Xu ZF,Wang MR,Li DT,Yang XS,Guo J

更新日期：2015-03-14 00:00:00

abstract：AIM:To investigate our clinical experience with the colonic manifestations of phosphatase and tensin homolog on chromosome ten (PTEN) hamartoma tumor syndrome (PHTS) and to perform a systematic literature review regarding the same. METHODS:This study was approved by the appropriate institutional review board prior to ...

journal_title：World journal of gastroenterology

authors： Stanich PP,Pilarski R,Rock J,Frankel WL,El-Dika S,Meyer MM

更新日期：2014-02-21 00:00:00

abstract：AIM:To classify gallstone disease as a basis for assessment of post-cholecystectomy symptoms. METHODS:One hundred and fifty three patients with a clinical and ultrasonographic diagnosis of gallstones filled out a structured questionnaire on abdominal pain symptoms and functional gastrointestinal disorder (FGID) before...

journal_title：World journal of gastroenterology

authors： Schmidt M,Søndenaa K,Dumot JA,Rosenblatt S,Hausken T,Ramnefjell M,Njølstad G,Eide GE

更新日期：2012-03-28 00:00:00

abstract：AIM:To investigate the hotspots, direction, and the time course of evolution of hepatitis A virus in the process of consecutive cell culture passage in human KMB17 diploid cells. METHODS:Wild type hepatitis A virus H2w was serially propagated in KMB17 cells until passage 30, and the full-length genomes of H2w and its ...

journal_title：World journal of gastroenterology

authors： Tang CH,Mao JS,Chai SA,Chen Y,Zhuang FC

更新日期：2007-09-14 00:00:00

abstract：AIM:To establish a model for prognosis assessment of extranodal follicular dendritic cell (FDC) sarcoma. METHODS:Nine lesions were examined by routine and molecular approaches. Clinicopathological factors from the new cases and 97 reported cases were analyzed for their prognostic values. RESULTS:The current lesions w...

journal_title：World journal of gastroenterology

authors： Li L,Shi YH,Guo ZJ,Qiu T,Guo L,Yang HY,Zhang X,Zhao XM,Su Q

更新日期：2010-05-28 00:00:00

abstract：AIM:To investigate H(+), K(+)-ATPase inhibition, anti-H pylori, antioxidant, and the in vivo antiulcer potential of a pectic polysaccharide from Swallow root (Decalepis hamiltonii; SRPP). METHODS:SRPP, with known sugar composition [rhamnose: arabinose: xylose: galactose in the ratio of 16:50:2:32 (w/w), with 141 mg/g ...

journal_title：World journal of gastroenterology

authors： Srikanta B,Siddaraju M,Dharmesh S

更新日期：2007-10-21 00:00:00

abstract：AIM:To prepare and characterize polyclonal antibodies against aldose reductase-like (ARL-1) protein. METHODS:ARL-1 gene was inserted into the E. coli expression vector pGEX-4T-1(His)(6)C and vector pQE-30. Recombinant ARL-1 proteins named ARL-(His)(6) and ARL-GST were expressed. They were purified by affinity chromato...

journal_title：World journal of gastroenterology

authors： Jin JF,Yuan LD,Liu L,Zhao ZJ,Xie W

更新日期：2003-07-01 00:00:00

abstract：:Helicobacter pylori (H pylori), a gastric pathogen, is a major cause of chronic gastritis and peptic ulcer disease, and is an important risk factor for the development of gastric malignancies. Culture of the bacterium from gastric biopsy is essential for the determination of drug resistance of H pylori. However, the i...

journal_title：World journal of gastroenterology

authors： Yin Y,He LH,Zhang JZ

更新日期：2009-03-28 00:00:00

abstract：AIM:To clarify the association of glypican-3 (GPC3) expression with Wnt and other growth signaling molecules in hepatocellular carcinoma (HCC). METHODS:Expression of GPC3, Wnt, matrix metalloproteinases (MMPs), sulfatase (SULF)1, SULF2, and other growth signaling molecules was analyzed in HCC cell lines and tissue sam...

journal_title：World journal of gastroenterology

authors： Akutsu N,Yamamoto H,Sasaki S,Taniguchi H,Arimura Y,Imai K,Shinomura Y

更新日期：2010-07-28 00:00:00

abstract：AIM:To investigate the prognostic value of the expression of connexin (Cx) 26, 32 and 43 messenger RNA (mRNA) in hepatocellular carcinoma (HCC) tissues. METHODS:Using a reverse-transcriptase polymerase chain reaction (RT-PCR), Cx 26, Cx 32 and Cx 43 mRNAs were determined in the liver tissues of 15 controls and in HCC ...

journal_title：World journal of gastroenterology

authors： Sheen IS,Jeng KS,Wang PC,Shih SC,Chang WH,Wang HY,Chen CC,Shyung LR

更新日期：2004-10-01 00:00:00

abstract：:Severe acute hepatitis of unknown etiology is difficult to treat and often progresses to subacute fulminant hepatitis or late-onset hepatic failure. A 45-year-old well-nourished, healthy man had progressive fatigue and his liver function tests showed severe liver dysfunction. The etiology of sever acute cholestatic he...

journal_title：World journal of gastroenterology

authors： Ohwada S,Kobayashi I,Harasawa N,Tsuda K,Inui Y

更新日期：2009-06-21 00:00:00

abstract：AIM:To analyze the benefits and harms of pancreatic cancer screening in familial high-risk individuals (HRIs). METHODS:Studies were identified by searching PubMed, EBSCO, ClinicalTrials.gov and the Cochrane database from database inception to June 2014. We also obtained papers from the reference lists of pertinent stu...

journal_title：World journal of gastroenterology

authors： Lu C,Xu CF,Wan XY,Zhu HT,Yu CH,Li YM

更新日期：2015-07-28 00:00:00

abstract：AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

journal_title：World journal of gastroenterology

authors： Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

更新日期：2011-05-07 00:00:00

abstract：:The bacterium Helicobacter pylori (H. pylori) infects the stomachs of approximately 50% of all humans. With its universal occurrence, high infectivity and virulence properties it is considered as one of the most severe global burdens of modern humankind. It has accompanied humans for many thousands of years, and due t...

journal_title：World journal of gastroenterology

authors： Maixner F,Thorell K,Granehäll L,Linz B,Moodley Y,Rattei T,Engstrand L,Zink A

更新日期：2019-11-14 00:00:00

abstract：AIM:To investigate the effects of Terminalia arjuna (T. arjuna) extract on human hepatoma cell line (HepG2) and its possible role in induction of apoptosis. METHODS:Human hepatoma cells were treated with different concentrations of ethanolic extract of T. arjuna and its cytotoxicity effect was measured by trypan blue ...

journal_title：World journal of gastroenterology

authors： Sivalokanathan S,Vijayababu MR,Balasubramanian MP

更新日期：2006-02-21 00:00:00

abstract：BACKGROUND:Understanding the treatment landscape of inflammatory bowel diseases (IBD) is essential for improving disease management and patient outcomes. Brazil is the largest Latin American country, and it presents socioeconomic and health care differences across its geographical regions. This country has the highest ...

journal_title：World journal of gastroenterology

authors： Zaltman C,Parra RS,Sassaki LY,Santana GO,Ferrari MLA,Miszputen SJ,Amarante HMBS,Kaiser Junior RL,Flores C,Catapani WR,Parente JML,Bafutto M,Ramos O,Gonçalves CD,Guimaraes IM,da Rocha JJR,Feitosa MR,Feres O,Saad-Hossne

更新日期：2021-01-14 00:00:00

abstract：:AIM:To study the anticarcinogenic effect and acute toxicity of liver targeting mitoxantrone nanospheres.METHODS:The anticarcinogenic effect of mitoxan-trone polybutylcyanoacrylate nanoparticles (DHAQ-PBCA-NP) was investigated by using heterotopic and orthotopic transplantation models of human hepatocellular carcinoma ...

journal_title：World journal of gastroenterology

authors： Zhang ZR,He Q,Liao GT,Bai SH

更新日期：1999-12-01 00:00:00

abstract：:Fibroblast growth factor receptors (FGFRs) regulate a variety of cellular functions, from embryogenesis to adult tissue homeostasis. FGFR signaling also plays significant roles in the proliferation, invasion, and survival of several types of tumor cells. FGFR-induced alterations, including gene amplification, chromoso...

journal_title：World journal of gastroenterology

authors： Yashiro M,Matsuoka T

更新日期：2016-02-28 00:00:00

abstract：AIM:To enrich putative hepatic progenitors from the developing human fetal liver using CD34 as a marker. METHODS:Aborted fetuses of 13-20 wk were used for the isolation of liver cells. The cells were labeled with anti CD34; a marker used for isolating progenitor population and the cells were sorted using magnetic cell...

journal_title：World journal of gastroenterology

authors： Nyamath P,Alvi A,Habeeb A,Khosla S,Khan AA,Habibullah CM

更新日期：2007-04-28 00:00:00

abstract：AIM:To investigate the effects of small interference RNA (siRNA) targeting of Cdx2 on human gastric cancer MGC-803 cells in vitro and in vivo. METHODS:The recombinant pSilencer 4.1-Cdx2 siRNA plasmids were constructed and transfected into gastric cancer MGC-803 cells in vitro. The stable transfectants were selected. T...

journal_title：World journal of gastroenterology

authors： Wang XT,Xie YB,Xiao Q

更新日期：2012-04-28 00:00:00