Are gap junction gene connexins 26, 32 and 43 of prognostic values in hepatocellular carcinoma? A prospective study.

abstract：AIM:To study the expression of a disintegrin and metalloproteinase 17 (ADAM17) mRNA in hepatocellular carcinoma (HCC) and to evaluate the relationship between ADAM17 mRNA expression and clinicopathological features of HCC. METHODS:Hepatocellular carcinomas (HCC) from 31 cases were divided into small HCC (SHCC), nodula...

journal_title：World journal of gastroenterology

authors： Ding X,Yang LY,Huang GW,Wang W,Lu WQ

更新日期：2004-09-15 00:00:00

abstract：AIM:To develop a potent and safe gene therapy for esophageal cancer. METHODS:An expression vector carrying fusion suicide gene (yCDglyTK) and shRNA against vascular endothelial growth factor (VEGF) was constructed and delivered into EC9706 esophageal cancer cells by calcium phosphate nanoparticles (CPNP). To achieve t...

journal_title：World journal of gastroenterology

authors： Liu T,Wu HJ,Liang Y,Liang XJ,Huang HC,Zhao YZ,Liao QC,Chen YQ,Leng AM,Yuan WJ,Zhang GY,Peng J,Chen YH

更新日期：2016-06-21 00:00:00

abstract：AIM:To investigate the relationship between 579 G>T polymorphisms in the DNMT3B gene, which is involved in de novo methylation and associated with the risk of esophagus cancer (EC) in Chinese. METHODS:DNMT3B 579 G>T genotypes were determined by PCR-RFLP in 194 EC patients and 210 healthy controls matched for age and s...

journal_title：World journal of gastroenterology

authors： Fan H,Liu DS,Zhang SH,Hu JB,Zhang F,Zhao ZJ

更新日期：2008-04-14 00:00:00

abstract：AIM:To investigate the expression of gastrokine 1 (GKN1) in normal gastric mucosa, precancerous lesions and gastric cancer tissues, and to analyse its correlations with tumour site and pathological pattern. METHODS:Thirty gastric cancer patients (12 cases of diffuse type and 18 cases of intestinal type), 13 atrophic g...

journal_title：World journal of gastroenterology

authors： Guo XY,Dong L,Qin B,Jiang J,Shi AM

更新日期：2014-11-28 00:00:00

abstract：AIM:To investigate whether α-fetoprotein (AFP) and vascular endothelial growth factor receptor (VEGFR)-1 correlate with early recurrence of hepatoma/hepatocellular carcinoma (HCC). METHODS:From 2000 to 2005, 114 consecutive patients with HCC underwent primary curative hepatectomy. The mean age was 60.7 (8.7) years and...

journal_title：World journal of gastroenterology

authors： Kamiyama T,Takahashi M,Nakanishi K,Yokoo H,Kamachi H,Kobayashi N,Ozaki M,Todo S

更新日期：2012-01-28 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, and three cases have been previously described in India in which GBS was associated with acute hepatitis E. A molecular mimicry mechanism is s...

journal_title：World journal of gastroenterology

authors： Loly JP,Rikir E,Seivert M,Legros E,Defrance P,Belaiche J,Moonen G,Delwaide J

更新日期：2009-04-07 00:00:00

abstract：:Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative "surprises". A 63-year-old woman, presented with a symptomatic huge abdominal cystic mass, underwent complete resection of the mass with safety margins. Histopathologi...

journal_title：World journal of gastroenterology

authors： Beuran M,Venter MD,Dumitru L

更新日期：2006-06-21 00:00:00

abstract：AIM:To analyze, retrospectively in a population-based study, the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS:All rectal carcinomas diagnosed during 1998 to 2000 and initially treated w...

journal_title：World journal of gastroenterology

authors： Bakx R,Visser O,Josso J,Meijer S,Slors JF,van Lanschot JJ

更新日期：2008-10-21 00:00:00

abstract：AIM:To evaluate the clinical advantages of single-port laparoscopic hepatectomy (SPLH) compare to multi-port laparoscopic hepatectomy (MPLH). METHODS:We retrospectively reviewed the medical records of 246 patients who underwent laparoscopic liver resection between January 2008 and December 2015 at our hospital. We div...

journal_title：World journal of gastroenterology

authors： Han JH,You YK,Choi HJ,Hong TH,Kim DG

更新日期：2018-01-21 00:00:00

abstract：AIM:To evaluate the expression of epithelial markers of colorectal carcinogenesis in patients with long-term ulcerative colitis (UC) and primary sclerosing cholangitis (PSC) before and after transplantation. METHODS:Eight patients with UC and PSC prior to liver transplantation (PSC-UC), 22 patients with UC after liver...

journal_title：World journal of gastroenterology

authors： Wohl P,Hucl T,Drastich P,Kamenar D,Spicak J,Honsova E,Sticova E,Lodererova A,Matous J,Hill M,Wohl P,Kucera M

更新日期：2013-01-01 00:00:00

abstract：AIM:To explore the effects of the nucleoside analogues beta-L-D4A and beta-LPA on hepatitis B virus (HBV) promoters. METHODS:Four HBV promoters were amplified by polymerase chain reaction (PCR) and subcloned into the expression vector pEGFP-1. The four recombinants controlled by HBV promoters were confirmed by restric...

journal_title：World journal of gastroenterology

authors： He XX,Lin JS,Chang Y,Zhang YH,Li Y,Wang XY,Xu D,Cheng XM

更新日期：2008-03-28 00:00:00

abstract：AIM:To investigate the acute toxicity, phytochemical profile, antidiarrheal activity and mechanisms of action of Maytenus erythroxylon (M. erythroxylon) ethanol extract. METHODS:A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity. Intestinal transit and gastric emptying protocols were used ...

journal_title：World journal of gastroenterology

authors： Formiga RO,Quirino ZGM,Diniz MFFM,Marinho AF,Tavares JF,Batista LM

更新日期：2017-06-28 00:00:00

abstract：AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

journal_title：World journal of gastroenterology

authors： Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

更新日期：2011-05-07 00:00:00

abstract：AIM:To investigate the inhibitory effect and possible mechanism of action of schisandrin B in SC-B on gastric cancer cells in vitro. METHODS:SC-B consisted of schisandrin B, aloe-emodin, and Astragalus polysaccharides. Exponentially growing human gastric cancer SGC-7901 cells were divided into six treatment groups: (1...

journal_title：World journal of gastroenterology

authors： Liu XN,Zhang CY,Jin XD,Li YZ,Zheng XZ,Li L

更新日期：2007-12-28 00:00:00

abstract：:Idiopathic achalasia is a rare primary motility disorder of the esophagus. The classical features are incomplete relaxation of a frequently hypertensive lower esophageal sphincter (LES) and a lack of peristalsis in the tubular esophagus. These motor abnormalities lead to dysphagia, stasis, regurgitation, weight loss, ...

journal_title：World journal of gastroenterology

authors： Eckardt AJ,Eckardt VF

更新日期：2009-08-28 00:00:00

abstract：:High-quality data remains scarce in terms of optimal management strategies in the elderly inflammatory bowel disease (IBD) population. Indeed, available trials have been mostly retrospective, of small sample size, likely owing to under-representation of such a population in the major randomized controlled trials. Howe...

journal_title：World journal of gastroenterology

authors： LeBlanc JF,Wiseman D,Lakatos PL,Bessissow T

更新日期：2019-08-14 00:00:00

abstract：AIM:To clarify the pathogenesis of gastroesophageal reflux disease symptoms in non-erosive reflux disease (NERD) patients. METHODS:Thirty-five NERD patients with persistent symptoms, despite taking rabeprazole 10 mg twice daily for at least 8 wk, were included in this study. All patients underwent 24 h combined impeda...

journal_title：World journal of gastroenterology

authors： Nakagawa K,Koike T,Iijima K,Saito M,Kikuchi H,Hatta W,Ara N,Uno K,Asano N,Shimosegawa T

更新日期：2015-12-21 00:00:00

abstract：AIM:To examine an increased risk of esophageal adenocarcinoma is restricted to patients who develop Barrett's esophagus or whether esophagitis per se is a risk factor for adenocarcinoma. METHODS:A population-based cohort of patients with histological evidence of esophagitis without Barrett's esophagus was constructed ...

journal_title：World journal of gastroenterology

authors： Murphy SJ,Anderson LA,Johnston BT,Fitzpatrick DA,Watson PR,Monaghan P,Murray LJ

更新日期：2005-12-14 00:00:00

abstract：:Confocal laser endomicroscopy (CLE) is a newly introduced procedure that provide real-time, high-resolution imaging of the gastrointestinal mucosa during endoscopy, allowing the visualization of the pathology of the mucosal epithelium with its cellular and subcellular structures. Recently, the use of CLE was reported ...

journal_title：World journal of gastroenterology

authors： De Palma GD,Rispo A

更新日期：2013-09-14 00:00:00

abstract：AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis. METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine, butyrate, or saline. Enemas were administered twice a week in the ...

journal_title：World journal of gastroenterology

authors： Pacheco RG,Esposito CC,Müller LC,Castelo-Branco MT,Quintella LP,Chagas VL,de Souza HS,Schanaider A

更新日期：2012-08-28 00:00:00

abstract：AIM:To detect the expression of DPC4 in malignant and non-malignant specimens of human pancreas, and observe the inhibition of retroviral pLXSN containing DPC4 on pancreatic carcinoma cells in vitro. METHODS:The expression of DPC4 was determined in 40 pancreatic adenocarcinoma and 36 non-malignant pancreatic specimens...

journal_title：World journal of gastroenterology

authors： Shen W,Tao GQ,Li DC,Zhu XG,Bai X,Cai B

更新日期：2008-10-28 00:00:00

abstract：AIM:To prospectively investigate the detection rate of laterally spreading tumors (LSTs) of the colorectum by computed tomography (CT) colonography (CTC). METHODS:Patients with LSTs measuring ≥ 20 mm detected during colonoscopy were prospectively enrolled in the study. All patients underwent colonoscopy and subsequent...

journal_title：World journal of gastroenterology

authors： Togashi K,Utano K,Kijima S,Sato Y,Horie H,Sunada K,Lefor AT,Sugimoto H,Yasuda Y

更新日期：2014-12-14 00:00:00

abstract：AIM:To investigate the characteristics of slow electrical waves and the presence of transient receptor potential melastatin-type 7 (TRPM7) in the human gastrointestinal (GI) tract. METHODS:Conventional microelectrode techniques were used to record intracellular electrical responses from human GI smooth muscle tissue. ...

journal_title：World journal of gastroenterology

authors： Kim BJ,Park KJ,Kim HW,Choi S,Jun JY,Chang IY,Jeon JH,So I,Kim SJ

更新日期：2009-12-14 00:00:00

abstract：AIM:To investigate the pattern of mucin expression and concentration in bile obtained during endoscopic retrograde cholangiography (ERC) in relation to gallstone disease. METHODS:Bile samples obtained at ERC from 29 consecutive patients, 17 with and 12 without gallstone disease were evaluated for mucin content by gel ...

journal_title：World journal of gastroenterology

authors： Vilkin A,Geller A,Levi Z,Niv Y

更新日期：2009-05-21 00:00:00

abstract：AIM:To analyze the safety and efficiency of direct-acting antiviral (DAA) regimens in liver-transplanted patients with hepatitis C virus (HCV) reinfection. METHODS:Between January 2014 and December 2016, 39 patients with HCV reinfection after liver transplantation were treated at our tertiary referral center with sofo...

journal_title：World journal of gastroenterology

authors： Rupp C,Hippchen T,Neuberger M,Sauer P,Pfeiffenberger J,Stremmel W,Gotthardt DN,Mehrabi A,Weiss KH

更新日期：2018-03-28 00:00:00

abstract：AIM:Passive immunotherapy using antibody against hepatitis B surface antigen (HBsAg) has been advocated in certain cases of Hepatitis B infection. We had earlier reported on the cloning and expression of a high affinity scFv derived from a mouse monoclonal (5S) against HBsAg. However this mouse antibody cannot be used ...

journal_title：World journal of gastroenterology

authors： Bose B,Khanna N,Acharya SK,Sinha S

更新日期：2005-12-28 00:00:00

abstract：AIM:Previous reports have shown that decrease in plasma glutamine (Gln) level following major surgery may contribute to the state of immunosuppression. Gln supplementation improves the depletion of body Gln pool, and may have indirect effect on reducing proinflammatory mediator release. This study evaluated whether the...

journal_title：World journal of gastroenterology

authors： Lin MT,Kung SP,Yeh SL,Liaw KY,Wang MY,Kuo ML,Lee PH,Chen WJ

更新日期：2005-10-21 00:00:00

abstract：AIM:To study the viscoelastic properties of human hepatocytes and hepatocellular carcinoma (HCC) cells under cytoskeletal perturbation, and to further to study the viscoelastic properties and the adhesive properties of mouse hepatoma cells (HTC) in different cell cycle. METHODS:Micropipette aspiration technique was ad...

journal_title：World journal of gastroenterology

authors： Zhang G,Long M,Wu ZZ,Yu WQ

更新日期：2002-04-01 00:00:00

abstract：AIM:To investigate the effect of Clostridium difficile (C. difficile) infection in an interleukin 10-deficient (IL-10(-/-)) mouse model of inflammatory bowel disease. METHODS:Bone marrow-derived dendritic cells isolated from wild type (WT) and IL-10(-/-)mice were stimulated for 4 h with C. difficile toxin A (200 μg/mL...

journal_title：World journal of gastroenterology

authors： Kim MN,Koh SJ,Kim JM,Im JP,Jung HC,Kim JS

更新日期：2014-12-07 00:00:00

abstract：AIM:To determine the utility of endoscopic ultrasound-guided biliary drainage (EUS-BD) with a fully covered self-expandable metal stent for managing malignant biliary stricture. METHODS:We collected data from 13 patients who presented with malignant biliary obstruction and underwent EUS-BD with a nitinol fully covered...

journal_title：World journal of gastroenterology

authors： Kim TH,Kim SH,Oh HJ,Sohn YW,Lee SO

更新日期：2012-05-28 00:00:00