Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection.

abstract：AIM:To understand CD133 promoter hypermethylation and expression in 32 colorectal cancer cell lines. METHODS:Nucleic acid was isolated from 32 colorectal cancer cell lines and CD133 expression levels were measured by reverse transcription-polymerase chain reaction (RT-PCR) and real-time PCR. Promoter methylation statu...

journal_title：World journal of gastroenterology

authors： Jeon YK,Kim SH,Choi SH,Kim KH,Yoo BC,Ku JL,Park JG

更新日期：2010-07-07 00:00:00

abstract：AIM:To investigate in patients with functional dyspepsia (FD) after an every-day meal whether (1) gastrointestinal (GI) and extra-GI symptoms had any relation with the degree of antral volume, (2) the onset of postprandial symptoms was associated with, and may predict, delayed gastric emptying. METHODS:In 94 symptomat...

journal_title：World journal of gastroenterology

authors： Pallotta N,Pezzotti P,Corazziari E

更新日期：2006-11-21 00:00:00

abstract：AIM:To investigate the pattern of mucin expression and concentration in bile obtained during endoscopic retrograde cholangiography (ERC) in relation to gallstone disease. METHODS:Bile samples obtained at ERC from 29 consecutive patients, 17 with and 12 without gallstone disease were evaluated for mucin content by gel ...

journal_title：World journal of gastroenterology

authors： Vilkin A,Geller A,Levi Z,Niv Y

更新日期：2009-05-21 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer and has a 5-year survival of < 5%. Only about 15% of the patients present with a resectable PDAC with potential to undergo "curative" surgery. After surgery, local and systemic recurrence, is though very common. The median survival ...

journal_title：World journal of gastroenterology

authors： Ansari D,Gustafsson A,Andersson R

更新日期：2015-03-21 00:00:00

abstract：:Despite major improvements concerning its diagnosis and treatment, pancreatic ductal adenocarcinoma (PDAC) remains an aggressive disease with an extremely poor prognosis. Pathology, as interface discipline between basic and clinical medicine, has substantially contributed to the recent developments and has laid the ba...

journal_title：World journal of gastroenterology

authors： Esposito I,Konukiewitz B,Schlitter AM,Klöppel G

更新日期：2014-10-14 00:00:00

abstract：BACKGROUND:Incidence and severity variations of inflammatory bowel disease (IBD) have been reported from Western populations between continents and regions of the same countries. However, no data were available from other countries. AIM:To investigate the regional differences in the IBD profiles of pediatric patients ...

journal_title：World journal of gastroenterology

authors： El Mouzan MI,AlEdreesi MH,Hasosah MY,Al-Hussaini AA,Al Sarkhy AA,Assiri AA

更新日期：2020-01-28 00:00:00

abstract：:Oncological treatment is currently directed toward a tailored therapy concept. Squamous cell carcinoma of the anal canal could be considered a suitable platform to test new therapeutic strategies to minimize treatment morbidity. Standard of care for patients with anal canal cancer consists of a combination of radiothe...

journal_title：World journal of gastroenterology

authors： De Nardi P,Carvello M,Staudacher C

更新日期：2012-11-28 00:00:00

abstract：AIM:To investigate the therapeutic efficacy and complications of splenectomy with endoscopic variceal ligation (EVL) and splenectomy with pericardial devascularization (i.e. Hassab's operation) in patients with portal hypertension. METHODS:A total of 103 patients with liver cirrhosis and portal hypertension were rando...

journal_title：World journal of gastroenterology

authors： Lin N,Liu B,Xu RY,Fang HP,Deng MH

更新日期：2006-12-07 00:00:00

abstract：:Endoscopic mucosal resection (EMR) allows the removal of flat or sessile lesions, laterally spreading tumors, and carcinoma of the colon or the rectum limited to the mucosa or the superficial submucosa. Acute appendicitis is the most common abdominal emergency requiring emergency surgery, and it is also a rare complic...

journal_title：World journal of gastroenterology

authors： Nemoto Y,Tokuhisa J,Shimada N,Gomi T,Maetani I

更新日期：2015-07-21 00:00:00

abstract：:Alcohol-related cirrhosis is a consequence of heavy and prolonged drinking. Similarly to patients with cirrhosis of other etiologies, patients with alcoholic cirrhosis develop portal hypertension and the hepatic, splanchnic and systemic hemodynamic alterations that follow. However, in alcoholic cirrhosis, some specifi...

journal_title：World journal of gastroenterology

authors： Bolognesi M,Verardo A,Di Pascoli M

更新日期：2014-07-07 00:00:00

abstract：:Mastocytosis is a clonal neoplastic disorder of the mast cells (MC) that can be limited to the skin (cutaneous mastocytosis) or involve one or more extracutaneous organs (systemic mastocytosis). The clinical manifestations of mastocytosis are heterogeneous ranging from indolent disease with a long-term survival to a h...

journal_title：World journal of gastroenterology

authors： Martins C,Teixeira C,Ribeiro S,Trabulo D,Cardoso C,Mangualde J,Freire R,Gamito É,Alves AL,Cremers I,Alves C,Neves A,Oliveira AP

更新日期：2016-07-28 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography (ERCP) is a state of the art diagnostic and therapeutic procedure for various pancreatic and biliary problems. In spite of the well-established safety of the procedure, there is still a risk of complications such as pancreatitis, cholangitis, bleeding and perforation. Air...

journal_title：World journal of gastroenterology

authors： Yilmaz B,Roach EC,Koklu S,Aydin O,Unlu O,Kilic YA

更新日期：2015-04-21 00:00:00

abstract：AIM:To study the relationship between Helicobacter pylori (H. pylori) and gastric carcinoma and its possible pathogenesis by H. pylori. METHODS:DNEL technique and immunohistochemical technique were used to study the state of apoptosis, proliferation and p53 gene expression. A total of 100 gastric mucosal biopsy specim...

journal_title：World journal of gastroenterology

authors： Zhang Z,Yuan Y,Gao H,Dong M,Wang L,Gong YH

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Acute liver failure (ALF) is a significant and complex hepatic insult that may rapidly progress to life-threatening conditions. Recently, menstrual blood stem cells (MenSCs) have been identified as a group of easily accessible mesenchymal stem cells with the advantages of non-invasive acquisition, low immuno...

journal_title：World journal of gastroenterology

authors： Cen PP,Fan LX,Wang J,Chen JJ,Li LJ

更新日期：2019-11-07 00:00:00

abstract：AIM:To further investigate the role of human B7 homolog 1 (B7-H1) in the mechanism of persistent hepatitis B virus (HBV) infection. METHODS:Peripheral and intra-hepatic B7-H1 expression were compared by flow cytometry and immunochemical staining between two 2 distinct groups, one being chronic HBV tolerance patients (C...

journal_title：World journal of gastroenterology

authors： Zhang WJ,Xie HY,Duan X,Wan YL,Peng CH,Shi SH,Su R,Zheng ZH,Pan LL,Zhou L,Zheng SS

更新日期：2012-07-28 00:00:00

abstract：AIM:To assess the value of magnetic resonance elastography (MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis (AIH). METHODS:In this retrospective study, 36 patients (19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a te...

journal_title：World journal of gastroenterology

authors： Wang J,Malik N,Yin M,Smyrk TC,Czaja AJ,Ehman RL,Venkatesh SK

更新日期：2017-02-07 00:00:00

abstract：AIM:To evaluate the effect of dietary cholesterol and serum total cholesterol (TC) on the risk of pancreatic cancer. METHODS:A literature search was performed up to June 2014 in PubMed, EMBASE, China National Knowledge Infrastructure and China Biology Medical literature database for relevant articles published in Engl...

journal_title：World journal of gastroenterology

authors： Wang J,Wang WJ,Zhai L,Zhang DF

更新日期：2015-03-28 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is a critical risk factor for the carcinogenesis and progression of hepatocellular carcinoma (HCC). It promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Effective antiviral treatments...

journal_title：World journal of gastroenterology

authors： Zhang YQ,Guo JS

更新日期：2015-04-07 00:00:00

abstract：AIM:To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS:We examined relationships between MVC and clinicopathological factors in 128 HC...

journal_title：World journal of gastroenterology

authors： Nanashima A,Nakayama T,Sumida Y,Abo T,Takeshita H,Shibata K,Hidaka S,Sawai T,Yasutake T,Nagayasu T

更新日期：2008-08-21 00:00:00

abstract：AIM:To investigate the effect of transfected survivin antisense oligonucleotide (ASODN) on proliferation and apoptosis of gastric cancer cells. METHODS:The authors designed ASODNs targeting different regions of survivin mRNA, including surviving ASODN1, ASODN2 and ASODN3. ASODNs were transfected into gastric cancer ce...

journal_title：World journal of gastroenterology

authors： Yang JH,Zhang YC,Qian HQ

更新日期：2004-04-15 00:00:00

abstract：:We have described a previously unreported entity of an intussuscepted neuroendocrine carcinoma of the appendix. Our patient was a 70-year-old man whose only complaint was insipient weight loss. Colonoscopy showed a malignant cecal "polyp", and an extended right hemicolectomy was performed. We have reviewed the literat...

journal_title：World journal of gastroenterology

authors： Thomas RE,Maude K,Rotimi O

更新日期：2006-02-14 00:00:00

abstract：AIM:To identify risk factors to help predict which patients are likely to fail to appear for an endoscopic procedure. METHODS:This was a retrospective, chart review, cohort study in a Canadian, tertiary care, academic, hospital-based endoscopy clinic. Patients included were: those undergoing esophagogastroduodenoscopy...

journal_title：World journal of gastroenterology

authors： Wong VK,Zhang HB,Enns R

更新日期：2009-06-21 00:00:00

abstract：:Neuroendocrine carcinoma (NEC) of the extrahepatic bile duct is rare, and only 22 cases have been reported. Only two of these were large-cell NEC (LCNEC); the vast majority were small-cell NEC. Here, we report a third case of LCNEC of the extrahepatic bile duct. A 76-year-old male presented to a local hospital with pa...

journal_title：World journal of gastroenterology

authors： Sasatomi E,Nalesnik MA,Marsh JW

更新日期：2013-07-28 00:00:00

abstract：AIM:To explore the expression of macrophage inflammatory protein-1alpha (MIP-1alpha) in Kupffer cells (KCs) following liver ischemia/reperfusion injury IRI in rats. METHODS:Forty male SD rats were divided randomly into five groups. A model of partial warm ischemia/reperfusion injury in the rat liver was established. K...

journal_title：World journal of gastroenterology

authors： Ma W,Wang ZR,Shi L,Yuan Y

更新日期：2006-06-28 00:00:00

abstract：AIM:To describe the bowel habits and the prevalence of irritable bowel syndrome (IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS:This cross-sectional study was conducted at five major universities in Greater Beirut and its suburbs, between F...

journal_title：World journal of gastroenterology

authors： Costanian C,Tamim H,Assaad S

更新日期：2015-03-28 00:00:00

abstract：:Despite advances in the treatment of gastric cancer, it remains the world's second highest cause of cancer death. As gastric cancer is often diagnosed at an advanced stage, systemic chemotherapy is the mainstay of treatment for these patients. However, no standard palliative chemotherapy regimen has been accepted for ...

journal_title：World journal of gastroenterology

authors： Bilici A

更新日期：2014-04-14 00:00:00

abstract：:Dysphagia associated with esophageal mechanical obstruction is usually related to malignant esophageal diseases. Benign lesions are rarely a cause for this type of dysphagia, and usually occur either as an intramural tumor or as an extrinsic compression. Mediastinal tuberculous lymphadenitis is rare in adults, and eve...

journal_title：World journal of gastroenterology

authors： Pimenta AP,Preto JR,Gouveia AM,Fonseca E,Pimenta MM

更新日期：2007-12-07 00:00:00

abstract：AIM:To induce the tolerance of rat liver allograft by dendritic cells (DCs) modified with NF-kappaB decoy oligodeoxynucleotides (ODNs). METHODS:Bone marrow (BM)-derived DCs from SD rats were propagated in the presence of GM-CSF or GM-CSF+IL-4 to obtain immature DCs or mature DCs. GM-CSF+IL-4-propagated DCs were treate...

journal_title：World journal of gastroenterology

authors： Xu MQ,Suo YP,Gong JP,Zhang MM,Yan LN

更新日期：2004-08-15 00:00:00

abstract：:Thiopurine analogs and anti-tumor necrosis factor (TNF) agents have dramatically changed the therapeutics of inflammatory bowel diseases (IBD), improving short and long-term outcomes. Unfortunately some patients do not respond to therapy and others lose response over time. The pharmacokinetic properties of these drugs...

journal_title：World journal of gastroenterology

authors： Yarur AJ,Abreu MT,Deshpande AR,Kerman DH,Sussman DA

更新日期：2014-04-07 00:00:00

abstract：:Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though only on the basis of...

journal_title：World journal of gastroenterology

authors： Fedeli U,Girardi P,Mastrangelo G

更新日期：2019-09-07 00:00:00