Pathology of pancreatic ductal adenocarcinoma: facts, challenges and future developments.

abstract：AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

journal_title：World journal of gastroenterology

authors： Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

更新日期：2018-12-21 00:00:00

abstract：:Gastric cancer is the second leading cause of cancer mortality worldwide. The diagnosis of gastric cancer has been significantly improved with the broad availability of gastrointestinal endoscopy. Effective technologies for accurate staging and quantitative evaluation are still in demand to merit reasonable treatment ...

journal_title：World journal of gastroenterology

authors： Wu CX,Zhu ZH

更新日期：2014-04-28 00:00:00

abstract：AIM:To investigate the apoptotic effect of photoexcited titanium dioxide (TiO(2)) nanoparticles in the presence of visible light on human hepatoma cell line (Bel 7402) and to study the underlying mechanism. METHODS:Cerium-element-doped titanium dioxide nanoparticles were prepared by impregnation method. Bel 7402 human...

journal_title：World journal of gastroenterology

authors： Wang L,Mao J,Zhang GH,Tu MJ

更新日期：2007-08-07 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00

abstract：:Celiac disease is an immune-mediated disorder that causes severe architectural disturbance in the small intestinal mucosa of genetically-predisposed individuals. Impaired absorption of multiple nutrients results and diarrhea and weight loss develop. Evidence has accumulated that a strict gluten-free diet can result in...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2017-04-21 00:00:00

abstract：AIM:To investigate the effects of 7.5% hypertonic saline on positive fluid balance and negative fluid balance, after radical surgery for gastrointestinal carcinoma. METHODS:Fifty-two patients with gastrointestinal carcinoma undergoing radical surgery were studied. The patients were assigned to receive either Ringer la...

journal_title：World journal of gastroenterology

authors： Shao YS,Zhang YT,Peng KQ,Quan ZY

更新日期：2005-03-21 00:00:00

abstract：AIM:To evaluate the efficacy and safety of HL tablet extracted from magnolia officinalis for treating patients with nonalcoholic fatty liver disease (NAFLD). METHODS:Seventy-four patients with NAFLD diagnosed by ultrasonography were randomly assigned to 3 groups given high dose (400 mg) HL tablet, low dose (133.4 mg) ...

journal_title：World journal of gastroenterology

authors： Jeong JY,Sohn JH,Baek YH,Cho YK,Kim Y,Kim H

更新日期：2017-08-28 00:00:00

abstract：AIM:Various side effects have been reported in patients infected with hepatitis C virus (HCV) who were treated with interferon-alpha (IFN-alpha), including the appearance or exacerbation of underlying autoimmune diseases and the development of a variety of organ and non-organ specific autoantibodies (NOSA). However, ve...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Georgiadou SP,Tassopoulos N,Zachou K,Liaskos C,Hatzakis A,Dalekos GN

更新日期：2005-01-28 00:00:00

abstract：AIM:To study the expression and serum level of HBxAg, Fas and FasL in tissues of HCC patients, and to assess the relationship between HBxAg and Fas/FasL system. METHODS:Tissues from 50 patients with HCC were tested for the expression of HBxAg, Fas and FasL by S-P immunohistochemistry. Serum levels of sFas/sFasL and HB...

journal_title：World journal of gastroenterology

authors： Wang XZ,Chen XC,Chen YX,Zhang LJ,Li D,Chen FL,Chen ZX,Chen HY,Tao QM

更新日期：2003-12-01 00:00:00

abstract：AIM:Passive immunotherapy using antibody against hepatitis B surface antigen (HBsAg) has been advocated in certain cases of Hepatitis B infection. We had earlier reported on the cloning and expression of a high affinity scFv derived from a mouse monoclonal (5S) against HBsAg. However this mouse antibody cannot be used ...

journal_title：World journal of gastroenterology

authors： Bose B,Khanna N,Acharya SK,Sinha S

更新日期：2005-12-28 00:00:00

abstract：AIM:To review the cases reported in the literature, examined their clinicopathological features, and evaluated the efficacy of different therapeutic modalities for this rare condition. METHODS:A search of the MEDLINE database revealed 16 cases of pericarditis carcinomatosa (PC) originating from GC reported in the lite...

journal_title：World journal of gastroenterology

authors： Kobayashi M,Okabayashi T,Okamoto K,Namikawa T,Araki K

更新日期：2005-11-28 00:00:00

abstract：AIM:To report on our large German collective and updated data of 142 patients with autoimmune hepatitis (AIH) type 1. METHODS:Key investigations performed were liver biopsy, serum autoantibodies as well as serum markers such as IgG and elevated transaminases. Antinuclear antigen (ANA) and smooth muscle antigen (SMA) a...

journal_title：World journal of gastroenterology

authors： Teufel A,Wörns M,Weinmann A,Centner C,Piendl A,Lohse AW,Galle PR,Kanzler S

更新日期：2006-09-14 00:00:00

abstract：AIM:To assess long-term effects of Helicobacter pylori (H pylori) eradication on antral G cell morphology and function in patients with and without duodenal ulcer (DU). METHODS:Consecutive dyspeptic patients referred to the endoscopy entered the study. Out of 39 H pylori positive patients, 8 had DU (H pylori +DU) and ...

journal_title：World journal of gastroenterology

authors： Sokic-Milutinovic A,Todorovic V,Milosavljevic T,Micev M,Drndarevic N,Mitrovic O

更新日期：2005-07-21 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis for the diagnostic accuracy of in vivo lesion characterization in colonic inflammatory bowel disease (IBD), using optical imaging techniques, including virtual chromoendoscopy (VCE), dye-based chromoendoscopy (DBC), magnification endoscopy and confocal laser endomicr...

journal_title：World journal of gastroenterology

authors： Lord R,Burr NE,Mohammed N,Subramanian V

更新日期：2018-03-14 00:00:00

abstract：AIM:To assess CD163 expression in plasma and peripheral blood and analyze its association with disease in acute-on-chronic hepatitis B liver failure (ACHBLF) patients. METHODS:A retrospective study was conducted from January 1, 2011 to January 1, 2012. Forty patients with ACHBLF (mean age 44.48 ± 12.28 years, range 18...

journal_title：World journal of gastroenterology

authors： Ye H,Wang LY,Zhao J,Wang K

更新日期：2013-05-14 00:00:00

abstract：BACKGROUND:Public awareness of colorectal cancer (CRC) and uptake of CRC screening remain challenges. The viewpoints of the target population (asymptomatic individuals older than 50) regarding CRC screening information sources and the reasons for and against participation in CRC screening are not well known in the Czec...

journal_title：World journal of gastroenterology

authors： Kroupa R,Ondrackova M,Kovalcikova P,Dastych M,Pavlik T,Kunovsky L,Dolina J

更新日期：2019-03-07 00:00:00

abstract：:AIM:To construct Hsp90 antisense RNA eukaryotic expression vector, transfect it into SGC7901 and SGC7901/VCR of MDR-type human gastric cancer cell lines, HCC7402 of human hepatic cancer and Ec109 of human esophageal cancer cell lines, and to study the cell cycle distribution of the gene transected cells and their resp...

journal_title：World journal of gastroenterology

authors： Liu XL,Xiao B,Yu ZC,Guo JC,Zhao QC,Xu L,Shi YQ,Fan DM

更新日期：1999-06-01 00:00:00

abstract：AIM:To induce the tolerance of rat liver allograft by dendritic cells (DCs) modified with NF-kappaB decoy oligodeoxynucleotides (ODNs). METHODS:Bone marrow (BM)-derived DCs from SD rats were propagated in the presence of GM-CSF or GM-CSF+IL-4 to obtain immature DCs or mature DCs. GM-CSF+IL-4-propagated DCs were treate...

journal_title：World journal of gastroenterology

authors： Xu MQ,Suo YP,Gong JP,Zhang MM,Yan LN

更新日期：2004-08-15 00:00:00

abstract：:Primary liver cancer is the sixth most common cancer in the world and the third cause of cancer-related death. Hepatocellular carcinoma (HCC) represents more than 90% of primary liver cancers and generally occurs in patients with underlying chronic liver disease such as viral hepatitis, hemochromatosis, primary biliar...

journal_title：World journal of gastroenterology

authors： van Meer S,de Man RA,Siersema PD,van Erpecum KJ

更新日期：2013-10-28 00:00:00

abstract：AIM:To investigate the pattern of mucin expression and concentration in bile obtained during endoscopic retrograde cholangiography (ERC) in relation to gallstone disease. METHODS:Bile samples obtained at ERC from 29 consecutive patients, 17 with and 12 without gallstone disease were evaluated for mucin content by gel ...

journal_title：World journal of gastroenterology

authors： Vilkin A,Geller A,Levi Z,Niv Y

更新日期：2009-05-21 00:00:00

abstract：AIM:To determine the mechanical properties of anastomotic colonic tissue in experimental settings and therefore give a measure of wound healing. METHODS:Thirty-six male Wistar rats were used as experimental models of anastomotic tissue integrity. On the 5th post-operative day, the tensile strength was measured by appl...

journal_title：World journal of gastroenterology

authors： Ekmektzoglou KA,Zografos GC,Kourkoulis SK,Dontas IA,Giannopoulos PK,Marinou KA,Poulakou MV,Perrea DN

更新日期：2006-09-21 00:00:00

abstract：:Patients with ulcerative colitis (UC) and Crohn's disease (CD) are at increased risk for developing colorectal cancer (CRC), and this is believed to be a result of chronic inflammation. Although conclusive evidence is still missing, both epidemiological and experimental observations suggest that certain drugs used to ...

journal_title：World journal of gastroenterology

authors： Stolfi C,Pellegrini R,Franze E,Pallone F,Monteleone G

更新日期：2008-07-28 00:00:00

abstract：AIM:Oxygen free radical mediated tissue damage is well established in pathogenesis of acute pancreatitis (AP). Whether nitric oxide (NO) plays a deleterious or a protective role is unknown. In alcohol-induced AP, we studied NO, lipooxidative damage and glutathione in pancreas, lung and circulation. METHODS:AP was indu...

journal_title：World journal of gastroenterology

authors： Andican G,Gelisgen R,Unal E,Tortum OB,Dervisoglu S,Karahasanoglu T,Burçak G

更新日期：2005-04-21 00:00:00

abstract：:Hepatitis C virus (HCV) infects approximately 170 million individuals worldwide. Prevention of HCV infection complications is based on antiviral therapy with the combination of pegylated interferon alfa and ribavirin. The use of serological and virological tests has become essential in the management of HCV infection ...

journal_title：World journal of gastroenterology

authors： Chevaliez S,Pawlotsky JM

更新日期：2007-05-07 00:00:00

abstract：:Although the lung is the major site for Mycobacterium tuberculosis infection, gastrointestinal involvement can be present as part of multiorgan disease process or, less commonly, can be seen as primary gastrointestinal tuberculosis. In the cases where the culture is negative, it can be difficult to differentiate tuber...

journal_title：World journal of gastroenterology

authors： Settbas Y,Alper M,Akcan Y,Gurbuz Y,Oksuz S

更新日期：2003-10-01 00:00:00

abstract：AIM:To determine the effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy. METHODS:Consecutive patients who underwent capsule endoscopy during the 16-mo study period were either given 250 mg oral erythromycin, 1 h prior to swallowing the capsule endoscope or nothing. The gastric and...

journal_title：World journal of gastroenterology

authors： Leung WK,Chan FK,Fung SS,Wong MY,Sung JJ

更新日期：2005-08-21 00:00:00

abstract：:AIM:To investigate the incidence and management of nutritional deficiencies following a gastrectomy.METHODS:A gastrectomy population of 227 patients in London was followed up for 30 years after operation to detect and treat nutritional deficiencies.RESULTS:By the end of the first decade iron deficiency was the commone...

journal_title：World journal of gastroenterology

authors： Tovey FI,Hobsley M

更新日期：2000-02-01 00:00:00

abstract：:One 63-year-old woman, who presented with cholestatic jaundice due to common bile duct compression produced by primary retroperitoneal fibrosis, is studied. The patient was operated six years ago because of hydronephrosis, when the disease was first diagnosed. Magnetic resonance cholangiopancreatography (MRCP) reveale...

journal_title：World journal of gastroenterology

authors： Zhao MF,Tian Y,Guo KJ,Ma ZG,Liao HH

更新日期：2004-10-15 00:00:00

abstract：AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy. METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre, were rev...

journal_title：World journal of gastroenterology

authors： Pang TC,Fung T,Samra J,Hugh TJ,Smith RC

更新日期：2011-03-28 00:00:00

abstract：AIM:To examine the expressions of matrix metalloproteinases-2 (MMP-2) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in rat fibrotic liver and in normal rat hepatic stellate cells, and to investigate the changes in their expressions in response to treatment with interleukin-10 (IL-10) and platelet-derived growth...

journal_title：World journal of gastroenterology

authors： Zhang LJ,Chen YX,Chen ZX,Huang YH,Yu JP,Wang XZ

更新日期：2004-09-01 00:00:00