Hepatitis C virus: virology, diagnosis and management of antiviral therapy.

abstract：AIM:To evaluate the effectiveness and safety of different portal vein branch embolization agents in inducing compensatory hypertrophy of the remnant liver and to offer a theoretic basis for clinical portal vein branch embolization. METHODS:Forty-one adult dogs were included in the experiment and divided into four grou...

journal_title：World journal of gastroenterology

authors： Huang JY,Yang WZ,Li JJ,Jiang N,Zheng QB

更新日期：2006-01-21 00:00:00

abstract：:Acute pancreatitis constitutes 3% of all admissions with abdominal pain. There are reports of osteal fat necrosis leading to periosteal reactions and osteolytic lesions following severe pancreatitis, particularly in long bones. A 54-year-old man was admitted to our hospital with acute pancreatitis, who later developed...

journal_title：World journal of gastroenterology

authors： Muthukumarasamy G,Shanmugam V,Yule SR,Ravindran R

更新日期：2007-07-21 00:00:00

abstract：:Because of the low prevalence of non-ampullary duodenal epithelial tumors (NADETs), standardized clinical management of sporadic superficial NADETs, including diagnosis, treatment, and follow-up, has not yet been established. Retrospective studies have revealed certain endoscopic findings suggestive of malignancy. Duo...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Tanaka M,Takizawa K,Ono H

更新日期：2014-09-21 00:00:00

abstract：AIM:To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA). METHODS:WB-F344 cells were continuously exposed to 7 x 10(-7) mol/L H2O2 for 21 d. Observations of cell morphology, colony formation rates, flow cyt...

journal_title：World journal of gastroenterology

authors： Han YY,Xue XW,Shi ZM,Wang PY,Wu XR,Wang XJ

更新日期：2014-02-07 00:00:00

abstract：:Transient thrombocytopenia is a common phenomenon after liver transplantation. After liver transplantation (LT), platelet count decreases and reaches a nadir on postoperative days 3-5, with an average reduction in platelet counts of 60%; platelet count recovers to preoperative levels approximately two weeks after LT. ...

journal_title：World journal of gastroenterology

authors： Takahashi K,Nagai S,Safwan M,Liang C,Ohkohchi N

更新日期：2018-04-07 00:00:00

abstract：AIM:To investigate the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in gastric carcinoma and its clinical significance and to explore its relationship with cell proliferation. METHODS:Expressions of IGFBP-2 and Ki-67 in 118 cases of gastric carcinoma and 40 cases of normal gastric mucosa were d...

journal_title：World journal of gastroenterology

authors： Shi LH,Zhu XQ,Zhao GH,Xia YB,Zhang YS

更新日期：2006-10-21 00:00:00

abstract：:Many of the drugs currently used in medical practice are racemates. The enantiomers of a racemic drug differ in pharmacodynamics and/or pharmacokinetics, thus in some cases it is preferable to develop pure enantiomers by racemic switch. In a recent study by Pai et al, dexrabeprazole [R(+)-rabeprazole] (10 mg) was foun...

journal_title：World journal of gastroenterology

authors： Zhou Q,Yan XF,Pan WS,Zeng S

更新日期：2008-04-28 00:00:00

abstract：:P21-activated kinases (PAKs) are central players in various oncogenic signaling pathways. The six PAK family members are classified into group I (PAK1-3) and group II (PAK4-6). Focus is currently shifting from group I PAKs to group II PAKs. Group II PAKs play important roles in many fundamental cellular processes, som...

journal_title：World journal of gastroenterology

authors： Shao YG,Ning K,Li F

更新日期：2016-01-21 00:00:00

abstract：:A preduodenal portal vein (PDPV) is known to be a rare cause of duodenal stenosis. We treated a 22-year-old male patient with malnutrition as a result of PDPV and a previously performed operation for scoliosis, who showed an improvement in quality of life after being treated with a combination of nutritional support a...

journal_title：World journal of gastroenterology

authors： Masumoto K,Teshiba R,Esumi G,Nagata K,Nakatsuji T,Nishimoto Y,Yamaguchi S,Sumitomo K,Taguchi T

更新日期：2009-08-21 00:00:00

abstract：AIM:To investigate the effect of epigallocatechin gallate (EGCG) on structural changes of gut microbiota in colorectal carcinogenesis. METHODS:An azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colitis mouse model was established. Forty-two female FVB/N mice were randomly divided into the following three group...

journal_title：World journal of gastroenterology

authors： Wang X,Ye T,Chen WJ,Lv Y,Hao Z,Chen J,Zhao JY,Wang HP,Cai YK

更新日期：2017-12-14 00:00:00

abstract：:While jejunoileal diverticula are rare and often asymptomatic, they may lead to chronic non-specific or acute symptoms. The large majority of complications present with an acute abdomen similar to appendicitis, cholecystitis or colonic diverticulitis but they also may appear with atypical symptoms. As a result, diagno...

journal_title：World journal of gastroenterology

authors： Kassahun WT,Fangmann J,Harms J,Bartels M,Hauss J

更新日期：2007-04-21 00:00:00

abstract：:The prognosis of patients with HCC still remains dismal. The life expectancy of HCC patients is hard to predict because of the high possibility of postoperative recurrence. Many factors, such as patient's general conditions, macroscopic tumor morphology, as well as tumor histopathology features, have been proven of pr...

journal_title：World journal of gastroenterology

authors： Qin LX,Tang ZY

更新日期：2002-04-01 00:00:00

abstract：AIM:To investigate the incidence, characteristics, and risk factors for hepatocellular carcinoma (HCC) in Chinese patients with primary biliary cirrhosis (PBC). METHODS:We reviewed the data of 52 PBC-associated HCC patients treated at Beijing 302 Hospital from January 2002 to December 2013 and analyzed its incidence a...

journal_title：World journal of gastroenterology

authors： Zhang XX,Wang LF,Jin L,Li YY,Hao SL,Shi YC,Zeng QL,Li ZW,Zhang Z,Lau GK,Wang FS

更新日期：2015-03-28 00:00:00

abstract：:Portal hypertension can be caused by a wide variety of conditions. It frequently presents with bleeding from esophageal varices. The approach to acute variceal hemorrhage in children is a stepwise progression from least invasive to most invasive. Management of acute variceal bleeding is straightforward. But data on pr...

journal_title：World journal of gastroenterology

authors： Gugig R,Rosenthal P

更新日期：2012-03-21 00:00:00

abstract：AIM:To study the value of colonoscopy and selective angiography in diagnosing ischemic enterocolitis. METHODS:Among the 16 cases under study, 10 cases had hypertension and a history of coronary artery disease (one was hospitalized for sub-ventricular-wall infarction). The blood pressure of 10 of the 16 cases ranged fr...

journal_title：World journal of gastroenterology

authors： He L,Luo HS

更新日期：2005-06-28 00:00:00

abstract：AIM:To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As₂O₃); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2. METHODS:Twenty patients with gastrointestin...

journal_title：World journal of gastroenterology

authors： Ma ZB,Xu HY,Jiang M,Yang YL,Liu LX,Li YH

更新日期：2014-05-14 00:00:00

abstract：AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

journal_title：World journal of gastroenterology

authors： Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

更新日期：2006-01-14 00:00:00

abstract：:Alcohol-induced fatty liver (steatosis) was believed to result from excessive generation of reducing equivalents from ethanol metabolism, thereby enhancing fat accumulation. Recent findings have revealed a more complex picture in which ethanol oxidation is still required, but specific transcription as well as humoral ...

journal_title：World journal of gastroenterology

authors： Donohue TM Jr

更新日期：2007-10-07 00:00:00

abstract：:RNA sequencing is the use of high throughput next generation sequencing technology to survey, characterize, and quantify the transcriptome of a genome. RNA sequencing has been used to analyze the pathogenesis of several malignancies such melanoma, lung cancer, and colorectal cancer. RNA sequencing can identify differe...

journal_title：World journal of gastroenterology

authors： Gao M,Zhong A,Patel N,Alur C,Vyas D

更新日期：2017-04-28 00:00:00

abstract：AIM:To investigate the effect of dermatan sulfate (DS) derivatives on platelet surface P-selectin expression and blood activated protein C (APC) activity in patients with inflammatory bowel disease (IBD), and to clarity the anti-inflammatory mechanism of DS derivatives. METHODS:Dermatan sulfate (DS) was sulfated with ...

journal_title：World journal of gastroenterology

authors： Ji SL,Du HY,Chi YQ,Cui HF,Cao JC,Geng MY,Guan HS

更新日期：2004-12-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries. NAFLD incorporates histologically and clinically different non-alcoholic entities; fatty liver (NAFL, steatosis hepatis) and steatohepatitis (NASH-characterised by...

journal_title：World journal of gastroenterology

authors： Firneisz G

更新日期：2014-07-21 00:00:00

abstract：AIM:To evaluate the myoelectric manifestations of peripheral fatigability in patients with primary biliary cirrhosis in comparison to healthy subjects. METHODS:Sixteen women with primary biliary cirrhosis without comorbidity and 13 healthy women matched for age and body mass index (BMI) completed the self-reported que...

journal_title：World journal of gastroenterology

authors： Biagini MR,Tozzi A,Grippo A,Galli A,Milani S,Amantini A

更新日期：2006-08-28 00:00:00

abstract：:Mesenchymal stem cells (MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro. It has recently been observed that MSC may also exert a profound immunosuppressive and anti-inflammatory effect both in vitro and in vivo with consequent potential use in autoimmune disorde...

journal_title：World journal of gastroenterology

authors： Taddio A,Tommasini A,Valencic E,Biagi E,Decorti G,De Iudicibus S,Cuzzoni E,Gaipa G,Badolato R,Prandini A,Biondi A,Ventura A

更新日期：2015-04-14 00:00:00

abstract：:Although a number of cases of hepatotoxicity are associated with the use of Hydroxycut weight management products, it has been alleged that their effects are primarily due to the presence of hydroxycitric acid (HCA, as Super CitriMax) in the formulations. However, while these products contain up to 20 different ingred...

journal_title：World journal of gastroenterology

authors： Stohs SJ,Preuss HG,Ohia SE,Kaats GR,Keen CL,Williams LD,Burdock GA

更新日期：2009-08-28 00:00:00

abstract：AIM:To compare two tests for exocrine pancreatic function (EPF) for use in M-ANNHEIM staging for pancreatitis. METHODS:One hundred and ninety four consecutive patients with acute pancreatitis (AP; n = 13), recurrent acute pancreatitis (RAP; n = 65) and chronic pancreatitis (CP; n = 116) were enrolled. EPF was assessed...

journal_title：World journal of gastroenterology

authors： Kamath MG,Pai CG,Kamath A,Kurien A

更新日期：2017-03-28 00:00:00

abstract：:There was remarkable progress in the understanding of the role genetic risk factors in chronic pancreatitis. These factors seem to be much more important than thought in the past. The rare autosomal-dominant mutations N29I and R122H of PRSS1 (cationic trypsinogen) as well as the variant N34S of SPINK1 (pancreatic secr...

journal_title：World journal of gastroenterology

authors： Keim V

更新日期：2008-02-21 00:00:00

abstract：AIM:To explore the efficacy and safety of herbal medicines (HM) in the treatment of irritable bowel syndrome (IBS). METHODS:A computer-based as well as manual literature search was performed. We reviewed randomized controlled trials on the treatment of IBS with and without HM. RESULTS:A total of 22 studies with 25 HM...

journal_title：World journal of gastroenterology

authors： Shi J,Tong Y,Shen JG,Li HX

更新日期：2008-01-21 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated wi...

journal_title：World journal of gastroenterology

authors： Wong F,Rayner-Hartley E,Byrne MF

更新日期：2014-09-14 00:00:00

abstract：AIM:To evaluate gallstone incidence and risk factors in a large population-based study. METHODS:Gallstone incidence and risk factors, were evaluated by structured questionnaire and physical examination, respectively, in 9611 of 11 109 (86.5%) subjects who were gallstone-free at the cross-sectional study. RESULTS:Six ...

journal_title：World journal of gastroenterology

authors： Festi D,Dormi A,Capodicasa S,Staniscia T,Attili AF,Loria P,Pazzi P,Mazzella G,Sama C,Roda E,Colecchia A

更新日期：2008-09-14 00:00:00

abstract：AIM:To investigate the effects of 7.5% hypertonic saline on positive fluid balance and negative fluid balance, after radical surgery for gastrointestinal carcinoma. METHODS:Fifty-two patients with gastrointestinal carcinoma undergoing radical surgery were studied. The patients were assigned to receive either Ringer la...

journal_title：World journal of gastroenterology

authors： Shao YS,Zhang YT,Peng KQ,Quan ZY

更新日期：2005-03-21 00:00:00