Effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy.

Abstract:

AIM:To determine the effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy. METHODS:Consecutive patients who underwent capsule endoscopy during the 16-mo study period were either given 250 mg oral erythromycin, 1 h prior to swallowing the capsule endoscope or nothing. The gastric and small bowel transit time, and the small bowel image quality were compared. RESULTS:Twenty-four patients received oral erythromycin whereas 14 patients were not given any prokinetic agent. Patients who received erythromycin had a significantly lower gastric transit time than control (16 min vs 70 min, P = 0.005), whereas the small bowel transit time was comparable between the two groups (227 min vs 183 min, P = 0.18). Incomplete small bowel examination was found in three patients of the control group and in one patient of the erythromycin group. There was no significant difference in the overall quality of small bowel images between the two groups. A marked reduction in gastric transit time was noted in two patients who had repeat capsule endoscopy after oral erythromycin. CONCLUSION:Use of oral erythromycin significantly reduces the gastric transit time of capsule endoscopy.

journal_name

World J Gastroenterol

authors

Leung WK,Chan FK,Fung SS,Wong MY,Sung JJ

doi

10.3748/wjg.v11.i31.4865

keywords:

subject

Has Abstract

pub_date

2005-08-21 00:00:00

pages

4865-8

issue

31

eissn

1007-9327

issn

2219-2840

journal_volume

11

pub_type

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