Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry.

abstract：AIM:To investigate the influence of the resection margin on local recurrence and survival in gastric cancer patients. METHODS:We reviewed the medical records of 1788 patients who had undergone gastrectomy for gastric cancer at the Seoul National University Bundang Hospital, South Korea, between May 2003 and July 2009....

journal_title：World journal of gastroenterology

authors： Lee CM,Jee YS,Lee JH,Son SY,Ahn SH,Park DJ,Kim HH

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the clinical utility of biological age (BA) measurement in screening colonoscopy for the detection of colorectal adenomas in the average-risk population. METHODS:A consecutive series of asymptomatic subjects aged ≥ 30 years who underwent colonoscopy in routine check-ups were enrolled. Colorectal ade...

journal_title：World journal of gastroenterology

authors： Kim SJ,Kim BJ,Kang H

更新日期：2017-10-07 00:00:00

abstract：AIM:To identify the risk factors for postoperative pulmonary complications (PPC) after gastrointestinal surgery. METHODS:A total of 1 002 patients undergoing gastrointestinal surgery in the Second Affiliated Hospital, Sun Yat-Sen University, during December 1999 and December 2003, were retrospectively studied. RESULT...

journal_title：World journal of gastroenterology

authors： Jiang SP,Li ZY,Huang LW,Zhang W,Lu ZQ,Zheng ZY

更新日期：2005-06-28 00:00:00

abstract：AIM:To identify the predictive clinicopathological factors for lymph node metastasis (LNM) in poorly differentiated early gastric cancer (EGC) and to further expand the possibility of using endoscopic mucosal resection (EMR) for the treatment of poorly differentiated EGC. METHODS:Data were collected from 85 poorly-dif...

journal_title：World journal of gastroenterology

authors： Li H,Lu P,Lu Y,Liu CG,Xu HM,Wang SB,Chen JQ

更新日期：2008-07-14 00:00:00

abstract：AIM:To investigate a potential role of S100A4 in esophagus squamous cell carcinoma metastasis (ESCCs). METHODS:Expression of S100A4 and E-cadherin were analyzed in frozen sections from ESCCs (metastasis, n = 28; non-metastasis, n = 20) by reverse transcription-polymerase chain reaction, quantitative polymerase chain r...

journal_title：World journal of gastroenterology

authors： Chen D,Zheng XF,Yang ZY,Liu DX,Zhang GY,Jiao XL,Zhao H

更新日期：2012-03-07 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive storage of fatty acids in the form of triglycerides in hepatocytes. It is most prevalent in western countries and includes a wide range of clinical and histopathological findings, namely from simple steatosis to steatohepatitis and fibrosis, which...

journal_title：World journal of gastroenterology

authors： Katsarou A,Moustakas II,Pyrina I,Lembessis P,Koutsilieris M,Chatzigeorgiou A

更新日期：2020-05-07 00:00:00

abstract：:Data from genome wide association studies and geoepidemiological studies established that a combination of genetic predisposition and environmental stimulation is required for the loss of tolerance in primary biliary cholangitis (PBC). The serologic hallmark of PBC are the presence of high titer anti-mitochondrial aut...

journal_title：World journal of gastroenterology

authors： Wang J,Yang G,Dubrovsky AM,Choi J,Leung PS

更新日期：2016-01-07 00:00:00

abstract：:In 2004, an association of genetic variation in the discs large homolog 5 (DLG5) gene with inflammatory bowel disease (IBD) was described in two large European study samples. The initial report of DLG5 as a novel IBD susceptibility gene sparked a multitude of studies investigating its effect on CD and IBD, respectivel...

journal_title：World journal of gastroenterology

authors： Friedrichs F,Stoll M

更新日期：2006-06-21 00:00:00

abstract：AIM:To investigate the effect of Lactobacillus-containing commercially available probiotic formulations in Germany during antibiotic treatment with an analysis of cost-efficiency. METHODS:In an observational study, we analyzed the frequency of bowel movements from 258 patients with infections in a primary care hospita...

journal_title：World journal of gastroenterology

authors： Dietrich CG,Kottmann T,Alavi M

更新日期：2014-11-14 00:00:00

abstract：:Helicobacter pylori (H pylori), a gastric pathogen, is a major cause of chronic gastritis and peptic ulcer disease, and is an important risk factor for the development of gastric malignancies. Culture of the bacterium from gastric biopsy is essential for the determination of drug resistance of H pylori. However, the i...

journal_title：World journal of gastroenterology

authors： Yin Y,He LH,Zhang JZ

更新日期：2009-03-28 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic granulomatous, and destructive inflammatory lesion of small intralobular and septal bile ducts, which is likely to be caused by an autoimmune mechanism with a the presence of serum antimitochondrial antibodies and a potential tendency to progress to ...

journal_title：World journal of gastroenterology

authors： Reshetnyak VI

更新日期：2015-07-07 00:00:00

abstract：AIM:To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS:Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function par...

journal_title：World journal of gastroenterology

authors： Pereira RM,dos Santos RA,Oliveira EA,Leite VH,Dias FL,Rezende AS,Costa LP,Barcelos LS,Teixeira MM,Simoes e Silva AC

更新日期：2008-07-28 00:00:00

abstract：:We herein report a case of bronchial bleeding after radical esophagectomy that was treated with lobectomy. A 65-year-old male who underwent subtotal esophagectomy with three-field lymph node dissection for esophageal carcinoma was referred to our hospital because of sudden hemoptysis. After the esophagectomy, bilatera...

journal_title：World journal of gastroenterology

authors： Kitajima T,Momose K,Lee S,Haruta S,Ueno M,Shinohara H,Fujimori S,Fujii T,Takei R,Kohno T,Udagawa H

更新日期：2015-03-21 00:00:00

abstract：:Portal hypertension can be caused by a wide variety of conditions. It frequently presents with bleeding from esophageal varices. The approach to acute variceal hemorrhage in children is a stepwise progression from least invasive to most invasive. Management of acute variceal bleeding is straightforward. But data on pr...

journal_title：World journal of gastroenterology

authors： Gugig R,Rosenthal P

更新日期：2012-03-21 00:00:00

abstract：AIM:To cure typically life-threatening esophagogastric anastomosis in rats, lacking anastomosis healing and sphincter function rescue, in particular. METHODS:Because we assume esophagogastric fistulas represent a particular NO-system disability, we attempt to identify the benefits of anti-ulcer stable gastric pentadec...

journal_title：World journal of gastroenterology

authors： Djakovic Z,Djakovic I,Cesarec V,Madzarac G,Becejac T,Zukanovic G,Drmic D,Batelja L,Zenko Sever A,Kolenc D,Pajtak A,Knez N,Japjec M,Luetic K,Stancic-Rokotov D,Seiwerth S,Sikiric P

更新日期：2016-11-07 00:00:00

abstract：AIM:To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia. METHODS:We genotyped 355 Estonians by polymerase chain reaction and direct sequencing. Milk consumption was analyzed by a que...

journal_title：World journal of gastroenterology

authors： Lember M,Torniainen S,Kull M,Kallikorm R,Saadla P,Rajasalu T,Komu H,Järvelä I

更新日期：2006-12-07 00:00:00

abstract：AIM:To investigate the expression and activity of leukotriene C4 (LTC4) synthesis enzymes and their underlying relationship with cysteinyl leukotriene (cys-LT) generation in a rat fulminant hepatic failure (FHF) model induced by D-galactosamine/lipopolysaccharide (D-GalN/ LPS). METHODS:Rats were treated with D-GalN (3...

journal_title：World journal of gastroenterology

authors： Ma KF,Yang HY,Chen Z,Qi LY,Zhu DY,Lou YJ

更新日期：2008-05-07 00:00:00

abstract：AIM:Previous reports have shown that decrease in plasma glutamine (Gln) level following major surgery may contribute to the state of immunosuppression. Gln supplementation improves the depletion of body Gln pool, and may have indirect effect on reducing proinflammatory mediator release. This study evaluated whether the...

journal_title：World journal of gastroenterology

authors： Lin MT,Kung SP,Yeh SL,Liaw KY,Wang MY,Kuo ML,Lee PH,Chen WJ

更新日期：2005-10-21 00:00:00

abstract：AIM:To investigate hepatitis B surface antigen (HBsAg) levels in patients with HBeAg-positive chronic hepatitis B (CHB) and different immune conditions. METHODS:HBeAg-positive CHB patients with different immune conditions were enrolled in this cross-sectional study. These patients were grouped according to the followi...

journal_title：World journal of gastroenterology

authors： Zhang YM,Yang YD,Jia HY,Zeng LY,Yu W,Zhou N,Li LJ

更新日期：2014-04-21 00:00:00

abstract：AIM:To investigate control of two different types of massive presacral bleeding according to the anatomy of the presacral venous system. METHODS:A retrospective review was performed in 1628 patients with middle or low rectal carcinoma who were treated surgically in the Department of Colorectal Surgery, Changhai Hospit...

journal_title：World journal of gastroenterology

authors： Lou Z,Zhang W,Meng RG,Fu CG

更新日期：2013-07-07 00:00:00

abstract：BACKGROUND:The Korea National Cancer Screening Program currently provides screening for colorectal cancer (CRC) for adults older than 50 years with no upper age limit. In general, people are likely to only pay attention to the benefits of cancer screening and to neglect its risks. Most consider the benefits of cancer s...

journal_title：World journal of gastroenterology

authors： Luu XQ,Lee K,Lee YY,Suh M,Kim Y,Choi KS

更新日期：2020-07-21 00:00:00

abstract：AIM:To investigate the role of transforming growth factor (TGF)-β-inducible early gene 1 (TIEG1) in TGF-β-induced growth inhibition in hepatocellular carcinoma (HCC) cells. METHODS:Human hepatocyte and HCC cell lines with varied susceptibilities to TGF-β1 were tested by methylthiazoletetrazolium (MTT) assay. The expre...

journal_title：World journal of gastroenterology

authors： Jiang L,Lai YK,Zhang JF,Chan CY,Lu G,Lin MC,He ML,Li JC,Kung HF

更新日期：2012-05-07 00:00:00

abstract：:The combination of either boceprevir or telaprevir with ribavirin and interferon (triple therapy) has been shown to be more effective than ribavirin+interferon (dual therapy) for the treatment of genotype 1 hepatitis C. Since the benefit of these treatments takes place after years, simulation models are needed to pred...

journal_title：World journal of gastroenterology

authors： Messori A,Fadda V,Maratea D,Trippoli S

更新日期：2012-06-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a dismal prognosis, especially when diagnosed at advanced stages. Annexin A2 (ANXA2), is found to promote cancer progression and therapeutic resistance. However, the underlining mechanisms of ANXA2 in immune escape of HCC remain poorly underst...

journal_title：World journal of gastroenterology

authors： Qiu LW,Liu YF,Cao XQ,Wang Y,Cui XH,Ye X,Huang SW,Xie HJ,Zhang HJ

更新日期：2020-05-14 00:00:00

abstract：:H. pylori is probably the most prevalent human pathogen worldwide. Since it was initially suggested in 1983 by Marshall and Warren to be implicated in gastritis and peptic ulcer disease, H. pylori has also been implicated in gastric carcinoma and was classified as a class I carcinogen. In the last two decades, a notew...

journal_title：World journal of gastroenterology

authors： Beswick EJ,Suarez G,Reyes VE

更新日期：2006-09-21 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the associatio...

journal_title：World journal of gastroenterology

authors： Trifan A,Stanciu C,Girleanu I,Stoica OC,Singeap AM,Maxim R,Chiriac SA,Ciobica A,Boiculese L

更新日期：2017-09-21 00:00:00

abstract：AIM:To identify the susceptible gene (s) for type 2 diabetes in the previously mapped region, 1p36.33-p36.23, in Han population of North China using single nucleotide polymorphisms (SNPs) and to analyze the haplotypes of the gene (s) related to type 2 diabetes. METHODS:Twenty three SNPs located in 10 candidate genes i...

journal_title：World journal of gastroenterology

authors： Li YF,Sun HX,Wu GD,Du WN,Zuo J,Shen Y,Qiang BQ,Yao ZJ,Wang H,Huang W,Chen Z,Xiong MM,Meng Y,Fang FD

更新日期：2003-09-01 00:00:00

abstract：AIM:To explore risk factors for lymph node metastases in early gastric cancer (EGC) and to confirm the appropriate range of lymph node dissection. METHODS:A total of 202 patients with EGC who underwent curative gastrectomy with lymphadenectomy in the Department of Surgery, Xinhua Hospital and Ruijin Hospital of Shangh...

journal_title：World journal of gastroenterology

authors： Ren G,Cai R,Zhang WJ,Ou JM,Jin YN,Li WH

更新日期：2013-05-28 00:00:00

abstract：AIM:To elucidate the expression of the apoptosis-associated molecules in human primary hepatocellular carcinoma (HCC) cells, and prepare the monoclonal antibodies (mAb) against the apoptosis-associated antigens of HCC cells. METHODS:Human HCC cell line HCC-9204 cells were induced apoptosis with 60 mL x L(-1) ethanol f...

journal_title：World journal of gastroenterology

authors： Yang LJ,Wang WL

更新日期：2002-10-01 00:00:00

abstract：AIM:To investigate the changes of gut microflora and endotoxin levels in rats with acute liver failure (ALF) induced by D-galactosamine (GalN). METHODS:Flora and endotoxin levels in the jejunum, ileum and colon in normal rats (group A) and rats with GalN -induced ALF were determined at 24 h (group B) or 48 h (group C)...

journal_title：World journal of gastroenterology

authors： Li LJ,Wu ZW,Xiao DS,Sheng JF

更新日期：2004-07-15 00:00:00