Role of discs large homolog 5.

abstract：AIM:To determine whether local antibiotic resistance involves P-glycoprotein (Pgp)-mediated active drug out-pumping during Helicobacter pylori (H pylori) infection treatment with classic antibiotic therapy. METHODS:Pgp activity was determined in gastric mucosa biopsy specimens obtained from 53 patients with pathohisto...

journal_title：World journal of gastroenterology

authors： Babic Z,Svoboda-Beusan I,Kucisec-Tepes N,Dekaris D,Troskot R

更新日期：2005-05-14 00:00:00

abstract：AIM:To investigate the effect of regulatory peptides bombesin (BBS) and neurotensin (NT) on intestinal barrier function in partially hepatectomized rats. METHODS:Ninety male Wistar rats were randomly divided into five groups: I (n=0): controls, II (n= 20): sham operated, III (n=20): partial hepatectomy 70% (PHx), IV (...

journal_title：World journal of gastroenterology

authors： Assimakopoulos SF,Alexandris IH,Scopa CD,Mylonas PG,Thomopoulos KC,Georgiou CD,Nikolopoulou VN,Vagianos CE

更新日期：2005-11-21 00:00:00

abstract：AIM:The purpose of the present study is to compare the optical properties of normal human colon mucosa/submucosa and muscle layer/chorion, and adenomatous human colon mucosa/submucosa and muscle layer/chorion in vitro at 476.5, 488, 496.5, 514.5 and 532 nm. We believe these differences in optical properties should help...

journal_title：World journal of gastroenterology

authors： Wei HJ,Xing D,Lu JJ,Gu HM,Wu GY,Jin Y

更新日期：2005-04-28 00:00:00

abstract：AIM:Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS:Thirty lesions each of hyperdense, isodense and hypodense attenua...

journal_title：World journal of gastroenterology

authors： Veit P,Kuehle C,Beyer T,Kuehl H,Bockisch A,Antoch G

更新日期：2006-04-21 00:00:00

abstract：AIM:To investigate the effects of KAI1/CD82 on biological behavior of colorectal carcinoma cells. METHODS:KAI1 cDNA was transfected into highly malignant colorectal carcinoma cell line, LoVo, which had low level of endogenous KAI1 expression, and established stable transfectant clones with high KAI1/CD82 expression. T...

journal_title：World journal of gastroenterology

authors： Liu L,Wu DH,Li ZG,Yang GZ,Ding YQ

更新日期：2003-06-01 00:00:00

abstract：AIM:To identify the clinicopathological predictors of lymph node (LN) metastasis and evaluate the outcomes of endoscopic submucosal dissection (ESD) in papillary adenocarcinoma-type early gastric cancers (EGCs). METHODS:From January 2005 to May 2013, 49 patients who underwent surgical operation and 24 patients who und...

journal_title：World journal of gastroenterology

authors： Lee HJ,Kim GH,Park DY,Lee BE,Jeon HK,Jhi JH,Song GA

更新日期：2015-04-07 00:00:00

abstract：AIM:To see the possibility of avoiding routine colostomy in patients presenting with unprepared bowel. METHODS:The cohort is composed of 103 patients, of these, 86 patients presented as emergencies (self-inflected and iatrogenic colon injuries, stab wounds and blast injury of the colon, volvulus sigmoid, obstructing l...

journal_title：World journal of gastroenterology

authors： Asfar SK,Al-Sayer HM,Juma TH

更新日期：2007-06-21 00:00:00

abstract：AIM:To detect the expression of mitochondrial uncoupling protein 2 (UCP2) in colon cancer and analyze the relation between UCP2 expression and clinical pathological features of colon cancer. METHODS:Fifteen colon tissue samples and 15 its adjacent tissue samples were obtained from colon cancer patients during surgical...

journal_title：World journal of gastroenterology

authors： Kuai XY,Ji ZY,Zhang HJ

更新日期：2010-12-07 00:00:00

abstract：AIM:To investigate the agreement and prognostic value of different measures of covert hepatic encephalopathy (CHE). METHODS:One-hundred-and-thirty-two cirrhotic outpatients underwent electroencephalography (EEG), paper-and-pencil psychometry (PHES) and critical flicker frequency, scored on the original/modified (CFFo/...

journal_title：World journal of gastroenterology

authors： Montagnese S,Balistreri E,Schiff S,De Rui M,Angeli P,Zanus G,Cillo U,Bombonato G,Bolognesi M,Sacerdoti D,Gatta A,Merkel C,Amodio P

更新日期：2014-11-14 00:00:00

abstract：:According to a meta-analysis, H pylori and non-steroidal anti-inflammatory drugs (NSAID) independently and significantly increase the risk of gastroduodenal ulcer and ulcer bleeding. Their coincidence is frequent, demonstration of a possible relationship and consequent attitude is of important implications. But unfort...

journal_title：World journal of gastroenterology

authors： Ji KY,Hu FL

更新日期：2006-06-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC), the fifth most common cancer in the world, shows increasing incidence worldwide. Curative treatments such as hepatectomy, liver transplantation, and radiofrequency ablation are applied in only 30%-60% of cases. Most remaining patients receive transarterial chemoembolization (TACE). Pati...

journal_title：World journal of gastroenterology

authors： Yamakado K,Hirota S

更新日期：2015-10-07 00:00:00

abstract：AIM:To assess the incidence and analyze the risk factors for Clostridium difficile-associated diarrhea (CDAD) after living donor liver transplantation (LDLT) in adult. METHODS:The microbiological data and medical records of 242 adult recipients that underwent LDLT at the Tokyo University Hospital were analyzed retrosp...

journal_title：World journal of gastroenterology

authors： Hashimoto M,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuch M

更新日期：2007-04-14 00:00:00

abstract：AIM:To investigate the role of MHC class II in the modulation of gastric epithelial cell apoptosis induced by H pylori infection. METHODS:After stimulating a human gastric epithelial cell line with bacteria or agonist antibodies specific for MHC class II and CD95, the quantitation of apoptotic and anti-apoptotic event...

journal_title：World journal of gastroenterology

authors： Bland DA,Suarez G,Beswick EJ,Sierra JC,Reyes VE

更新日期：2006-08-07 00:00:00

abstract：AIM:To retrospectively evaluate the vaccination-induced anti-HBs seroconversion rates in treatment-naive and treatment-experienced chronic hepatitis C (CHC) patients. Also to prospectively evaluate the seroconversion rates in CHC patients during pegylated interferon (PEG) plus ribavirin (RIB) treatment. METHODS:Sevent...

journal_title：World journal of gastroenterology

authors： Elefsiniotis IS,Vezali E,Kamposioras K,Pantazis KD,Tontorova R,Ketikoglou I,Moulakakis A,Saroglou G

更新日期：2006-07-21 00:00:00

abstract：:Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast e...

journal_title：World journal of gastroenterology

authors： Ohkura Y,Hashimoto M,Lee S,Sasaki K,Matsuda M,Watanabe G

更新日期：2014-07-07 00:00:00

abstract：AIM:To investigate the role of nuclear division cycle (NDC)80 in human hepatocellular carcinogenesis. METHODS:NDC80 gene expression was analyzed by real-time reverse transcription polymerase chain reaction in 47 paired hepatocellular carcinoma (HCC) and adjacent tissues. The HCC cell line SMMC-7721 was transfected wit...

journal_title：World journal of gastroenterology

authors： Ju LL,Chen L,Li JH,Wang YF,Lu RJ,Bian ZL,Shao JG

更新日期：2017-05-28 00:00:00

abstract：AIM:To investigate the association between interleukin-28B (IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus (HCV) genotype 4. METHODS:Two hundred and one HCV-genotype 4 patients were included. All patients were treated with Peginterferon alph2a/Ribavirin for 48 wk. End...

journal_title：World journal of gastroenterology

authors： Derbala M,Rizk N,Shebl F,Alkaabi S,Eldweik N,John A,Sharma M,Yaqoob R,Almohanadi M,Butt M,Alejji K

更新日期：2012-12-21 00:00:00

abstract：:While jejunoileal diverticula are rare and often asymptomatic, they may lead to chronic non-specific or acute symptoms. The large majority of complications present with an acute abdomen similar to appendicitis, cholecystitis or colonic diverticulitis but they also may appear with atypical symptoms. As a result, diagno...

journal_title：World journal of gastroenterology

authors： Kassahun WT,Fangmann J,Harms J,Bartels M,Hauss J

更新日期：2007-04-21 00:00:00

abstract：AIM:To investigate the expression of leukemia related protein 16 (LRP16), and the possible relationship between LRP16 expression and clinicopathological indices in 336 gastric carcinoma patients. METHODS:Immunohistochemistry was used to detect LRP16 expression in 336 cases of paraffin-embedded gastric carcinoma tissue...

journal_title：World journal of gastroenterology

authors： Li YZ,Zhao P,Han WD

更新日期：2009-10-14 00:00:00

abstract：:Functional gastrointestinal disorders (FGID) are heterogeneous disorders with a variety of clinical manifestations, primarily defined by signs and symptoms rather than a definite underlying cause. Their pathophysiology remains obscure and, although it is expected to differ according to the specific FGID, disruptions i...

journal_title：World journal of gastroenterology

authors： Koutouratsas T,Kalli T,Karamanolis G,Gazouli M

更新日期：2019-02-07 00:00:00

abstract：AIM:To analyze the available evidence about the risk of extrapancreatic malignancies and pancreatic ductal adenocarcinoma associated to pancreatic intraductal papillary mucinous tumors (IPMNs). METHODS:A systematic search of literature was undertaken using MEDLINE, EMBASE, Cochrane and Web-of-Science libraries. No lim...

journal_title：World journal of gastroenterology

authors： Baiocchi GL,Molfino S,Frittoli B,Pigozzi G,Gheza F,Gaverini G,Tarasconi A,Ricci C,Bertagna F,Grazioli L,Tiberio GA,Portolani N

更新日期：2015-06-21 00:00:00

abstract：:Sorafenib is the current standard treatment for advanced hepatocellular carcinoma (HCC), but its efficacy is modest with low response rates and short response duration. Predictive biomarkers for sorafenib efficacy are necessary. However, efforts to determine biomarkers for sorafenib have led only to potential candidat...

journal_title：World journal of gastroenterology

authors： Shao YY,Hsu CH,Cheng AL

更新日期：2015-09-28 00:00:00

abstract：AIM:To determine whether IFN-alpha is the agent that turns a slightly effective treatment (radiochemotherapy) into a potent therapy, we tested IFN-alpha for its synergistic properties. METHODS:Eight pancreatic carcinoma cell lines were treated with the single agents and combinations of these. The role of IFN-alpha reg...

journal_title：World journal of gastroenterology

authors： Ma JH,Patrut E,Schmidt J,Knaebel HP,Büchler MW,Märten A

更新日期：2005-03-14 00:00:00

abstract：AIM:To investigate the changes of gut microflora and endotoxin levels in rats with acute liver failure (ALF) induced by D-galactosamine (GalN). METHODS:Flora and endotoxin levels in the jejunum, ileum and colon in normal rats (group A) and rats with GalN -induced ALF were determined at 24 h (group B) or 48 h (group C)...

journal_title：World journal of gastroenterology

authors： Li LJ,Wu ZW,Xiao DS,Sheng JF

更新日期：2004-07-15 00:00:00

abstract：AIM:To investigate the reasons for the occurrence of the pink-color sign of iodine-unstained lesions. METHODS:In chromoendoscopy, the pink-color sign of iodine-unstained lesions is recognized as useful for the diagnosis of esophageal squamous cell carcinoma. Patients with superficial esophageal neoplasms treated by en...

journal_title：World journal of gastroenterology

authors： Ishihara R,Kanzaki H,Iishi H,Nagai K,Matsui F,Yamashina T,Matsuura N,Ito T,Fujii M,Yamamoto S,Hanaoka N,Takeuchi Y,Higashino K,Uedo N,Tatsuta M,Tomita Y,Ishiguro S

更新日期：2013-07-21 00:00:00

abstract：:Cytokines are indispensable signals of the mucosa-associated immune system for maintaining normal gut homeostasis. An imbalance of their profile in favour of inflammation initiation may lead to disease states, such as that is observed in inflammatory bowel diseases (IBD). Although Crohn's disease (CD) is often describ...

journal_title：World journal of gastroenterology

authors： Műzes G,Molnár B,Tulassay Z,Sipos F

更新日期：2012-11-07 00:00:00

abstract：:An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

journal_title：World journal of gastroenterology

authors： Byrnes V,Chopra S,Koziel MJ

更新日期：2007-08-21 00:00:00

abstract：AIM:To determine the clinical effectiveness of intense psychological support to physical activity (PA) in nonalcoholic fatty liver disease (NAFLD), compared with cognitive-behavioral treatment (CBT). METHODS:Twenty-two NAFLD cases received support to exercise, tailored to their motivational needs (PA group). The effec...

journal_title：World journal of gastroenterology

authors： Montesi L,Caselli C,Centis E,Nuccitelli C,Moscatiello S,Suppini A,Marchesini G

更新日期：2014-08-07 00:00:00

abstract：:Helicobacter pylori (H. pylori) is the causative agent of gastritis, peptic ulcer disease, mucosa associated lymphoid tissue lymphoma and gastric cancer (GC). While this bacterium infects 50% of the world's population, in Africa its prevalence reach as high as 80% as the infection is acquired during childhood. Risk fa...

journal_title：World journal of gastroenterology

authors： Smith S,Fowora M,Pellicano R

更新日期：2019-07-07 00:00:00

abstract：AIM:To investigate the effects of guggulsterone on the proliferation and apoptosis of human hepatoma HepG2 cells in vitro and relevant mechanisms. METHODS:Human hepatocellular carcinoma HepG2 cells and normal human liver L-02 cells were treated with different concentrations of guggulsterone (5-100 μmol/L) for 24-72 h....

journal_title：World journal of gastroenterology

authors： Shi JJ,Jia XL,Li M,Yang N,Li YP,Zhang X,Gao N,Dang SS

更新日期：2015-12-21 00:00:00