Synergistic effects of interferon-alpha in combination with chemoradiation on human pancreatic adenocarcinoma.

abstract：:AIM:To explore the expression and changes of hepatoma specific alkaline phospatase (ALP) in rats during canceration.METHODS:The ALPs and isoenzymes of rat livers and sera were investigated in SD hepatomas induced with 0.05% 2-fluoenylacetamide (2-FAA).RESULTS: By pathological examination and biochemical analysis. ALPs...

journal_title：World journal of gastroenterology

authors： Xiao MB,Yao DF,Zhang H,Qiang H,Huang JF,Wei Q,Jiang F

更新日期：1998-08-01 00:00:00

abstract：:Multiple studies have demonstrated alterations in the intestinal microbial community (termed the microbiome) in Crohn's disease (CD) and several lines of evidence suggest these changes may have a significant role in disease pathogenesis. In active and quiescent disease, both the faecal and mucosa-associated microbiome...

journal_title：World journal of gastroenterology

authors： Tawfik A,Flanagan PK,Campbell BJ

更新日期：2014-07-21 00:00:00

abstract：AIM:To detect microsatellite instability (MSI) in patients with hereditary nonpolyposis colorectal cancer or ordinary hereditary colorectal cancer and to provide criteria for screening the kindreds with hereditary nonpolyposis colorectal cancer at molecular level. METHODS:MSI was detected in the specimens from 20 case...

journal_title：World journal of gastroenterology

authors： Liu WZ,Jin F,Zhang ZH,Wang SB

更新日期：2006-08-07 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is the most common cause of hepatic fibrosis and hepatocellular carcinoma (HCC), mainly as a result of chronic necroinflammatory liver disease. A characteristic feature of chronic hepatitis B infection, alcoholic liver disease and nonalcoholic fatty liver disease (NAFLD) is he...

journal_title：World journal of gastroenterology

authors： Shimizu I,Kohno N,Tamaki K,Shono M,Huang HW,He JH,Yao DF

更新日期：2007-08-28 00:00:00

abstract：AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects, complications and parameters of systemic inflammatory response. METHODS:This was a randomized, experimental, survival study. Ten female mini pigs underwent NOTES t...

journal_title：World journal of gastroenterology

authors： Martínek J,Ryska O,Filípková T,Doležel R,Juhas S,Motlík J,Holubová M,Nosek V,Rotnáglová B,Zavoral M,Ryska M

更新日期：2012-07-21 00:00:00

abstract：AIM:To investigate the effect of side-stream smoking on gut microflora composition, intestinal inflammation and expression of tight junction proteins. METHODS:C57BL/6 mice were exposed to side-stream cigarette smoking for one hour daily over eight weeks. Cecal contents were collected for microbial composition analysis...

journal_title：World journal of gastroenterology

authors： Wang H,Zhao JX,Hu N,Ren J,Du M,Zhu MJ

更新日期：2012-05-14 00:00:00

abstract：:Dysphagia associated with esophageal mechanical obstruction is usually related to malignant esophageal diseases. Benign lesions are rarely a cause for this type of dysphagia, and usually occur either as an intramural tumor or as an extrinsic compression. Mediastinal tuberculous lymphadenitis is rare in adults, and eve...

journal_title：World journal of gastroenterology

authors： Pimenta AP,Preto JR,Gouveia AM,Fonseca E,Pimenta MM

更新日期：2007-12-07 00:00:00

abstract：AIM:To investigate the effects of restraint stress on chronic colitis in interleukin (IL)-10 deficient (IL-10(-/-)) mice. METHODS:The first experiment compared the effect of restraint stress on the development of intestinal inflammation in wild-type and IL-10(-/-) mice. Both wild-type and IL-10(-/-) mice were physical...

journal_title：World journal of gastroenterology

authors： Koh SJ,Kim JW,Kim BG,Lee KL,Kim JS

更新日期：2015-07-28 00:00:00

abstract：:The liver is the commonest site of distant metastasis of colorectal cancer and nearly half of the patients with colorectal cancer ultimately develop liver involved during the course of their diseases. Surgery is the only therapy that offers the possibility of cure for patients with hepatic metastatic diseases. Five-ye...

journal_title：World journal of gastroenterology

authors： Liu LX,Zhang WH,Jiang HC

更新日期：2003-02-01 00:00:00

abstract：AIM:To evaluate the efficacy and the safety of combined 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in refractory advanced colorectal carcinoma. METHODS:We initiated a regimen with at day 1 an injection (iv) of bevacizumab at 5 mg/kg, followed by 180 mg/m(2) irinotecan, followed by Leucovorin 400 mg/m(2), fo...

journal_title：World journal of gastroenterology

authors： Ghiringhelli F,Guiu B,Chauffert B,Ladoire S

更新日期：2009-09-14 00:00:00

abstract：:Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant recipients. Over the last two decades, various multidrug-resistant (MDR) pathogens have emerged as relevant causes of infection in this population. Although this fact reflects the spread of MDR pathogens in health care fac...

journal_title：World journal of gastroenterology

authors： Santoro-Lopes G,de Gouvêa EF

更新日期：2014-05-28 00:00:00

abstract：AIM:To establish a more sensitive method for detection of free cancer cells in peritoneal washes from gastric cancer patients during surgery and to evaluate its clinical significance. METHODS:The carcinoembryonic antigen (CEA) mRNA levels in peritoneal washes from 65 cases of gastric cancer were detected by real-time ...

journal_title：World journal of gastroenterology

authors： Zhang YS,Xu J,Luo GH,Wang RC,Zhu J,Zhang XY,Nilsson-Ehle P,Xu N

更新日期：2006-03-07 00:00:00

abstract：AIM:To clarify the effect of a high des-gamma-carboxy prothrombin (DCP) level on the invasiveness and prognosis of small hepatocellular carcinoma. METHODS:Among 142 consecutive patients with known DCP levels, who underwent hepatectomy because of hepatocellular carcinoma, 85 patients met the criteria for small hepatoce...

journal_title：World journal of gastroenterology

authors： Hakamada K,Kimura N,Miura T,Morohashi H,Ishido K,Nara M,Toyoki Y,Narumi S,Sasaki M

更新日期：2008-03-07 00:00:00

abstract：:We report an extremely rare case where a mesenchymal differentiation, especially embryonal sarcoma, was demonstrated in cholangiocarcinoma. At autopsy, a yellowish-white tumor (15 cm x 12 cm) was found in the right hepatic lobe, and there were several daughter nodules in both hepatic lobes. Histologically, most of the...

journal_title：World journal of gastroenterology

authors： Sumiyoshi S,Kikuyama M,Matsubayashi Y,Kageyama F,Ide Y,Kobayashi Y,Nakamura H

更新日期：2007-02-07 00:00:00

abstract：AIM:To select the peptide mimicking the neutralization epitope of hepatitis E virus which bound to non-type-specific and conformational monoclonal antibodies (mAbs) 8C11 and 8H3 fromed 7-peptide phage display library, and expressed the peptide recombinant with HBcAg in E.coli, and to observe whether the recombinant HBc...

journal_title：World journal of gastroenterology

authors： Gu Y,Zhang J,Wang YB,Li SW,Yang HJ,Luo WX,Xia NS

更新日期：2004-06-01 00:00:00

abstract：AIM:To investigate whether the simultaneous treatment with human growth hormone (hGH) abolishes the negative effects of everolimus on anastomotic healing. METHODS:Forty-eight male Sprague-Dawley-rats were randomized to three groups of 16 animals each (I: vehicle; II: everolimus 3 mg/kg po; III: everolimus 3 mg/kg po +...

journal_title：World journal of gastroenterology

authors： Küper MA,Trütschel S,Weinreich J,Königsrainer A,Beckert S

更新日期：2016-05-07 00:00:00

abstract：AIM:To evaluate the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in gastric carcinoma tissues and their clinical significance. METHODS:Western blot immune trace method was adopted to detect the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in 55 tissue s...

journal_title：World journal of gastroenterology

authors： Zhao XH,Gu SZ,Tian HG,Quan P,Pan BR

更新日期：2005-07-07 00:00:00

abstract：:Cholangiocarcinoma (CC) is rare malignant tumors composed of cells that resemble those of the biliary tract. It is notoriously difficult to diagnose, and is associated with a high mortality. Traditionally, CC is divided into intrahepatic and extrahepatic disease according to its location within the biliary tree. Intra...

journal_title：World journal of gastroenterology

authors： Shimoda M,Kubota K

更新日期：2007-03-14 00:00:00

abstract：:Increased numbers of mucosa-associated Escherichia coli are observed in both of the major inflammatory bowel diseases, Crohn d' disease (CD) and ulcerative colitis (UC). A potential pathophysiological link between the presence of pathogenic invasive bacteria and genetic host susceptibility of patients with ileal CD is...

journal_title：World journal of gastroenterology

authors： Barnich N,Darfeuille-Michaud A

更新日期：2007-11-14 00:00:00

abstract：AIM:To evaluate the best diagnostic technique and risk factors of the human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) infection in inflammatory bowel disease (IBD). METHODS:A cohort of 40 IBD patients (17 refractory) and 40 controls underwent peripheral blood and endoscopic colonic mucosal sample harvest. Vi...

journal_title：World journal of gastroenterology

authors： Ciccocioppo R,Racca F,Paolucci S,Campanini G,Pozzi L,Betti E,Riboni R,Vanoli A,Baldanti F,Corazza GR

更新日期：2015-02-14 00:00:00

abstract：:A clinical trial of radiotherapy with modified simultaneous integrated boost (SIB) technique against huge tumors was conducted. A 58-year-old male patient who had a huge pelvic tumor diagnosed as a rectal adenocarcinoma due to familial adenomatous polyposis was enrolled in this trial. The total dose of 77 Gy (equivale...

journal_title：World journal of gastroenterology

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Kawashiro S,Hagiwara M,Chin M,Hashizume E,Nemoto K

更新日期：2014-12-28 00:00:00

abstract：AIM:To investigate the expression of human telomerase reverse transcriptase gene (hTRT) in gastric cancer (GC) and its relevance with cell cycle regulators including P16INK4, cyclin and P53. METHODS:In situ hybridization (ISH) for hTRT mRNA was performed in 53 cases of gastric cancer and adjacent cancerous tissues. Im...

journal_title：World journal of gastroenterology

authors： Shao JC,Wu JF,Wang DB,Qin R,Zhang H

更新日期：2003-03-01 00:00:00

abstract：AIM:To evaluate the effects of ethanol on the insulin-like growth factor-I (IGF-I) system involved in c-Jun N-terminal kinase (JNK1/2) and alcoholdehydrogenase (ADH) activity in primary cultured rat hepatocytes. METHODS:Hepatocytes isolated from male Sprague-Dawley rats were incubated with various concentrations of et...

journal_title：World journal of gastroenterology

authors： Oh YI,Kim JH,Kang CW

更新日期：2008-07-21 00:00:00

abstract：:Recent advances in techniques of therapeutic endoscopy for stomach neoplasms are rapidly achieved. One of the major topics in this field is endoscopic submucosal dissection (ESD). ESD is a new endoscopic technique using cutting devices to remove the tumor by the following three steps: injecting fluid into the submucos...

journal_title：World journal of gastroenterology

authors： Fujishiro M

更新日期：2006-08-28 00:00:00

abstract：AIM:To examine the possible ameliorative effect of breastfeeding and the uptake of human colostrum against coeliac disease in autistic rats. METHODS:Female rats were fed a standard diet and received a single intraperitoneal injection of 600 mg/kg sodium valproate on day 12.5 after conception. In study 1, neonatal rats...

journal_title：World journal of gastroenterology

authors： Selim ME,Al-Ayadhi LY

更新日期：2013-06-07 00:00:00

abstract：AIM:To assess the efficacy and safety of a new treatment modality, cellular immune therapy based on personalized peptide vaccination (PPV-DC-CTL) combined with radiotherapy, for treating advanced hepatocellular carcinoma (HCC). METHODS:A total of nine patients with advanced HCC were enrolled. Multidisciplinary consult...

journal_title：World journal of gastroenterology

authors： Shen J,Wang LF,Zou ZY,Kong WW,Yan J,Meng FY,Chen FJ,Du J,Shao J,Xu QP,Ren HZ,Li RT,Wei J,Qian XP,Liu BR

更新日期：2017-08-07 00:00:00

abstract：AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy. METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre, were rev...

journal_title：World journal of gastroenterology

authors： Pang TC,Fung T,Samra J,Hugh TJ,Smith RC

更新日期：2011-03-28 00:00:00

abstract：AIM:To investigate the relationship between the polymorphism of class II transactivator (CIITA) gene promoters and chronic hepatitis B (CHB). METHODS:Genomic DNA was prepared from peripheral blood leukocytes. Promoters I, III and IV of gene were analyzed respectively with polymerase chain reaction single strand confor...

journal_title：World journal of gastroenterology

authors： Zhao YR,Gong L,He YL,Liu F,Lu C

更新日期：2005-02-14 00:00:00

abstract：AIM:To compare the follow-up outcomes of ileosigmoidal anastomosis (ISA) and caecorectal anastomosis (CRA) in patients with slow transit constipation (STC) with or without melanosis coli (MC). METHODS:We collected the clinical data of 48 STC patients with or without MC from May 2002 to May 2007. Twenty-six patients un...

journal_title：World journal of gastroenterology

authors： Sun JW,Gu JN,Du P,Chen W

更新日期：2015-09-07 00:00:00

abstract：:Alcohol-induced fatty liver (steatosis) was believed to result from excessive generation of reducing equivalents from ethanol metabolism, thereby enhancing fat accumulation. Recent findings have revealed a more complex picture in which ethanol oxidation is still required, but specific transcription as well as humoral ...

journal_title：World journal of gastroenterology

authors： Donohue TM Jr

更新日期：2007-10-07 00:00:00