Alcohol-induced steatosis in liver cells.

abstract：:Port site hernia develops through a fascial or peritoneal layer that was inadequate or not repaired. It is a rare complication of laparoscopic surgery which may lead to serious problems. Here, we present a 77-year-old female, diagnosed with a small bowel hernia through a 10-mm port site. We had performed ten cases of ...

journal_title：World journal of gastroenterology

authors： Lee JH,Kim W

更新日期：2008-11-28 00:00:00

abstract：:The use of thiopurines as immunosuppression for the treatment of refractory or chronic active inflammatory bowel disease is established for both Crohn's disease and ulcerative colitis. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine, 6-mercaptopurine and thioguanine. We wi...

journal_title：World journal of gastroenterology

authors： Frei P,Biedermann L,Nielsen OH,Rogler G

更新日期：2013-02-21 00:00:00

abstract：:Alverine citrate is a commonly used smooth muscle relaxant agent. A MEDLINE search on January 2004 revealed only 1 report implicating the hepatotoxicity of this agent. A 34-year-old woman was investigated because of the finding of elevated liver function tests on biochemical screening. Other etiologies of hepatitis we...

journal_title：World journal of gastroenterology

authors： Arhan M,Koklu S,Koksal AS,Yolcu OF,Koruk S,Koruk I,Kayacetin E

更新日期：2004-08-01 00:00:00

abstract：:The search for biomarkers that characterize specific aspects of inflammatory bowel disease (IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating ...

journal_title：World journal of gastroenterology

authors： Quetglas EG,Mujagic Z,Wigge S,Keszthelyi D,Wachten S,Masclee A,Reinisch W

更新日期：2015-11-28 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS:Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and ...

journal_title：World journal of gastroenterology

authors： Li M,Lu B,Chu L,Zhou H,Chen MY

更新日期：2014-04-07 00:00:00

abstract：AIM:To evaluate the expression of epithelial markers of colorectal carcinogenesis in patients with long-term ulcerative colitis (UC) and primary sclerosing cholangitis (PSC) before and after transplantation. METHODS:Eight patients with UC and PSC prior to liver transplantation (PSC-UC), 22 patients with UC after liver...

journal_title：World journal of gastroenterology

authors： Wohl P,Hucl T,Drastich P,Kamenar D,Spicak J,Honsova E,Sticova E,Lodererova A,Matous J,Hill M,Wohl P,Kucera M

更新日期：2013-01-01 00:00:00

abstract：AIM:To investigate the distribution pathway of metastatic lymph nodes in gastric carcinoma as a foundation for rational lymphadenectomy. METHODS:We investigated 173 cases with solitary or single station metastatic lymph nodes (LN) from among 2476 gastric carcinoma patients. The location of metastatic LN, histological ...

journal_title：World journal of gastroenterology

authors： Liu CG,Lu P,Lu Y,Jin F,Xu HM,Wang SB,Chen JQ

更新日期：2007-09-21 00:00:00

abstract：:The limited efficacy of cytotoxic therapy for advanced biliary tract and gallbladder cancers emphasizes the need for novel and more effective medical treatment options. A better understanding of the specific biological features of these neoplasms led to the development of new targeted therapies, which take the abundan...

journal_title：World journal of gastroenterology

authors： Hopfner M,Schuppan D,Scherubl H

更新日期：2008-12-14 00:00:00

abstract：AIM:To investigate the risk factors of colon cancer and rectal cancer. METHODS:A nested case-control study was conducted in a cohort of 64 693 subjects who participated in a colorectal cancer screening program from 1989 to 1998 in Jiashan county, Zhejiang, China. 196 cases of colorectal cancer were detected from 1990 ...

journal_title：World journal of gastroenterology

authors： Chen K,Cai J,Liu XY,Ma XY,Yao KY,Zheng S

更新日期：2003-01-01 00:00:00

abstract：:Chronic groin pain (Inguinodynia) following inguinal hernia repair is a significant, though under-reported problem. Mild pain lasting for a few days is common following mesh inguinal hernia repair. However, moderate to severe pain persisting more than 3 mo after inguinal herniorrhaphy should be considered as pathologi...

journal_title：World journal of gastroenterology

authors： Hakeem A,Shanmugam V

更新日期：2011-04-14 00:00:00

abstract：AIM:To investigate clinical characteristics and therapy of pancreatic encephalopathy (PE) and Wernicke encephalopathy (WE). METHODS:In a retrospective study of 596 patients with acute pancreatitis (AP), patients with PE were compared to those with WE in regards to history, clinical manifestation, diagnosis, treatment ...

journal_title：World journal of gastroenterology

authors： Sun GH,Yang YS,Liu QS,Cheng LF,Huang XS

更新日期：2006-07-14 00:00:00

abstract：AIM:To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device. METHODS:Seventy consecutive patients with 96 early esophageal neoplasms, who underwent ESD using a SB knife at Kure Medical Center and Chugoku Cancer Center, Japan, betwee...

journal_title：World journal of gastroenterology

authors： Kuwai T,Yamaguchi T,Imagawa H,Miura R,Sumida Y,Takasago T,Miyasako Y,Nishimura T,Iio S,Yamaguchi A,Kouno H,Kohno H,Ishaq S

更新日期：2018-04-21 00:00:00

abstract：:Alcohol consumption and hepatitis C virus (HCV) infection have a synergic hepatotoxic effect, and the coexistence of these factors increases the risk of advanced liver disease. The main mechanisms of this effect are increased viral replication and altered immune response, although genetic predisposition may also play ...

journal_title：World journal of gastroenterology

authors： Novo-Veleiro I,Alvela-Suárez L,Chamorro AJ,González-Sarmiento R,Laso FJ,Marcos M

更新日期：2016-01-28 00:00:00

abstract：:Liver cancer is one of the world's most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma (HCC), a primary hepatic cancer, accounts for 90%-95% of liver cancer cases. The pathogenesis of HCC consists of a stepwise process of liver damage that extends over decades, due to hepatitis,...

journal_title：World journal of gastroenterology

authors： Lu JW,Ho YJ,Yang YJ,Liao HA,Ciou SC,Lin LI,Ou DL

更新日期：2015-11-14 00:00:00

abstract：AIM:To establish novel intestinal myofibroblast (IMF) cell lines from mouse colonic mucosa and investigate their biological characters. METHODS:Primary IMFs were isolated from mucosal tissues of mouse colon that was denuded of epithelial cells and smooth muscle layer. For immortalization, primary IMFs were transfected...

journal_title：World journal of gastroenterology

authors： Kawasaki H,Ohama T,Hori M,Sato K

更新日期：2013-05-07 00:00:00

abstract：:AIM:To evaluate hepatic energy charge levels of the patients with hepatoma after hepatic artery embolization and its relation to postoperative complications.METHODS:Sixty-nine patients with hepatoma were continuously measured for their arterial blood ketone body ratio (AKBR) and compared with their postoperative clini...

journal_title：World journal of gastroenterology

authors： Li L,Yan LN,Chen XL,Lu WS,Xie XD,Wu YT

更新日期：1998-04-01 00:00:00

abstract：AIM:To investigate the expression of tumor suppressor gene p27 and spindle checkpoint gene Mad2 and to demonstrate their expression difference in colorectal cancer and normal mucosa and to evaluate its clinical significance. METHODS:Immunohistochemical staining was used for detection of expression of Mad2 and p27 in c...

journal_title：World journal of gastroenterology

authors： Li GQ,Zhang HF

更新日期：2004-11-01 00:00:00

abstract：:Despite advances in the treatment of gastric cancer, it remains the world's second highest cause of cancer death. As gastric cancer is often diagnosed at an advanced stage, systemic chemotherapy is the mainstay of treatment for these patients. However, no standard palliative chemotherapy regimen has been accepted for ...

journal_title：World journal of gastroenterology

authors： Bilici A

更新日期：2014-04-14 00:00:00

abstract：AIM:To investigate the association between cytokine gene polymorphism and disease status in chronic hepatitis C genotype 3 by liver biopsy, ALT, HCV RNA levels and response to treatment. METHODS:Patients with chronic hepatitis C genotype 3 were analyzed for single nucleotide polymorphisms of interleukin (IL)-10, IL-1 ...

journal_title：World journal of gastroenterology

authors： Abbas Z,Moatter T,Hussainy A,Jafri W

更新日期：2005-11-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a dismal prognosis, especially when diagnosed at advanced stages. Annexin A2 (ANXA2), is found to promote cancer progression and therapeutic resistance. However, the underlining mechanisms of ANXA2 in immune escape of HCC remain poorly underst...

journal_title：World journal of gastroenterology

authors： Qiu LW,Liu YF,Cao XQ,Wang Y,Cui XH,Ye X,Huang SW,Xie HJ,Zhang HJ

更新日期：2020-05-14 00:00:00

abstract：AIM:To investigate the relationship between glucose metabolism and glypican-3 (GPC3) expression in hepatocellular carcinoma (HCC). METHODS:Immunohistochemical staining of pathological samples for GPC3 and glucose transporter 1 (GLUT1), and whole-body 18F-FDG PET/CT for measuring tumour glucose uptake were performed in...

journal_title：World journal of gastroenterology

authors： Li YC,Yang CS,Zhou WL,Li HS,Han YJ,Wang QS,Wu HB

更新日期：2018-01-28 00:00:00

abstract：:High-risk human papillomavirus has been suggested as a risk factor for esophageal adenocarcinoma. Tumor human papillomavirus status has been reported to confer a favorable prognosis in esophageal adenocarcinoma. The size of the primary tumor and degree of lymphatic spread determines the prognosis of esophageal carcino...

journal_title：World journal of gastroenterology

authors： Sharma P,Gautam SD,Rajendra S

更新日期：2020-06-07 00:00:00

abstract：:Benign neoplasia of the duodenum are very rare. Moreover, duodenal tubulovillous adenomas are more uncommon lesions. The microscopic structure of tubulovillous adenoma has frond-like projection of mucosa with branching papillary structure and generally upward growth into the lumen. We describe a 72-year-old man who sh...

journal_title：World journal of gastroenterology

authors： Kim JH,Choi JW,Seo YS,Lee BJ,Yeon JE,Kim JS,Byun KS,Bak YT,Kim I,Park JJ

更新日期：2007-06-21 00:00:00

abstract：AIM:To evaluate the role of RARalpha gene in mediating the growth inhibitory effect of all-trans retinoic acid (ATRA) on gastric cancer cells. METHODS:The expression levels of retinoic acid receptors (RARs) in gastric cancer cells were detected by Northern blot. Transient transfection and chlorophenicol acetyl transfe...

journal_title：World journal of gastroenterology

authors： Liu S,Wu Q,Chen ZM,Su WJ

更新日期：2001-10-01 00:00:00

abstract：AIM:To investigate the effect of synbiotics, i.e. probiotics and prebiotics mixture, on the gut microbial ecology and digestive enzyme activities in rats. METHODS:Forty-eight SD rats weighing about 280 g were used in this study. Rats were divided into three groups according to the contents of probiotics and prebiotics...

journal_title：World journal of gastroenterology

authors： Yang SC,Chen JY,Shang HF,Cheng TY,Tsou SC,Chen JR

更新日期：2005-12-21 00:00:00

abstract：AIM:To retrospectively evaluate the prognosis of patients with hepatocellular carcinoma (HCC) with or without a history of therapy for HCC following transcatheter arterial embolization (TAE). METHODS:One hundred and twenty-one patients with HCC treated with TAE from 1992 to 2004 in our hospital were enrolled in this s...

journal_title：World journal of gastroenterology

authors： Hiraoka A,Kumagi T,Hirooka M,Uehara T,Kurose K,Iuchi H,Hiasa Y,Matsuura B,Michitaka K,Kumano S,Tanaka H,Yamashita Y,Horiike N,Mochizuki T,Onji M

更新日期：2006-04-07 00:00:00

abstract：:Surgical resection offers the best opportunity for survival in patients with colorectal cancer metastatic to the liver, with five-year survival rates up to 58% in selected cases. However, only a minority are resectable at the time of diagnosis. Continuous research in this field aims at increasing the percentage of pat...

journal_title：World journal of gastroenterology

authors： Misiakos EP,Karidis NP,Kouraklis G

更新日期：2011-09-28 00:00:00

abstract：AIM:To investigate the level of gastric ghrelin in stomach mucosa of dyspeptic patients in relation to Helicobacter pylori (H pylori) infection, bacterial cytotoxicity, topography and gender. METHODS:The study comprised 40 premenopausal women (19 H pylori positive) and 48 men (17 H pylori positive) with functional dys...

journal_title：World journal of gastroenterology

authors： Stec-Michalska K,Malicki S,Michalski B,Peczek L,Wisniewska-Jarosinska M,Nawrot B

更新日期：2009-11-21 00:00:00

abstract：AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects, complications and parameters of systemic inflammatory response. METHODS:This was a randomized, experimental, survival study. Ten female mini pigs underwent NOTES t...

journal_title：World journal of gastroenterology

authors： Martínek J,Ryska O,Filípková T,Doležel R,Juhas S,Motlík J,Holubová M,Nosek V,Rotnáglová B,Zavoral M,Ryska M

更新日期：2012-07-21 00:00:00

abstract：:Deficiencies in vitamins or other factors (B6, B12, folic acid, betaine) and genetic disorders for the metabolism of the non-protein amino acid-homocysteine (Hcy) lead to hyperhomocysteinemia (HHcy). HHcy is an integral component of several disorders including cardiovascular disease, neurodegeneration, diabetes and al...

journal_title：World journal of gastroenterology

authors： Ji C,Kaplowitz N

更新日期：2004-06-15 00:00:00