Abstract:
AIM:To investigate the risk factors of colon cancer and rectal cancer. METHODS:A nested case-control study was conducted in a cohort of 64 693 subjects who participated in a colorectal cancer screening program from 1989 to 1998 in Jiashan county, Zhejiang, China. 196 cases of colorectal cancer were detected from 1990 to 1998 as the case group and 980 non-colorectal cancer subjects, matched with factors of age, gender, resident location, were randomly selected from the 64 693 cohort as controls. By using univariate analysis and multivariate conditional logistic regression analysis, the odds ratio (OR) and its 95 % confidence interval (95 %CI) were calculated between colorectal cancer and personal habits, dietary factors, as well as intestinal related symptoms. RESULTS:The multivariate analysis results showed that after matched with age, sex and resident location, mucous blood stool history and mixed sources of drinking water were closely associated with colon cancer and rectal cancer, OR values for the mucous blood stool history were 3.508 (95 %CI: 1.370-8.985) and 2.139 (95 %CI: 1.040-4.402) respectively; for the mixed drinking water sources, 2.387 (95 %CI: 1.243-4.587) and 1.951 (95 %CI: 1.086-3.506) respectively. All reached the significant level with a P-value less than 0.05. CONCLUSION:The study suggested that mucous blood stool history and mixed sources of drinking water were the risk factors of colon cancer and rectal cancer. There was no any significant association between dietary habits and the incidence of colorectal cancer.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Chen K,Cai J,Liu XY,Ma XY,Yao KY,Zheng Sdoi
10.3748/wjg.v9.i1.99keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
99-103issue
1eissn
1007-9327issn
2219-2840journal_volume
9pub_type
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v20.i26.8717
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journal_title:World journal of gastroenterology
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v21.i42.11914
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doi:10.3748/wjg.v24.i43.4906
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doi:10.3748/wjg.v26.i39.5997
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v20.i23.7207
更新日期:2014-06-21 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v11.i6.899
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pub_type: 杂志文章
doi:10.3748/wjg.15.3901
更新日期:2009-08-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.15.2782
更新日期:2009-06-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v19.i41.7069
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v18.i6.541
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pub_type: 杂志文章
doi:10.3748/wjg.v18.i34.4787
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journal_title:World journal of gastroenterology
pub_type: 社论,评审
doi:10.3748/wjg.v19.i38.6319
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v13.i11.1680
更新日期:2007-03-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v19.i48.9485
更新日期:2013-12-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v21.i18.5560
更新日期:2015-05-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v11.i6.854
更新日期:2005-02-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.14.3518
更新日期:2008-06-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v12.i35.5668
更新日期:2006-09-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v26.i47.7497
更新日期:2020-12-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v12.i29.4628
更新日期:2006-08-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 临床试验,杂志文章
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更新日期:2004-08-01 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v11.i44.7024
更新日期:2005-11-28 00:00:00