When to stop nucleos(t)ide analogues treatment for chronic hepatitis B? Durability of antiviral response.

abstract：AIM:To investigate the accuracy of endoscopic or biopsy diagnoses of superficial nonampullary duodenal epithelial tumors (NADETs). METHODS:Clinicopathological data were reviewed for 84 superficial NADETs from 74 patients who underwent surgery or endoscopic resection between September 2002 and August 2014 at a single p...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Sasaki K,Kawata N,Tanaka M,Takizawa K,Imai K,Hotta K,Matsubayashi H,Ono H

更新日期：2015-05-14 00:00:00

abstract：AIM:To investigate the association between TP53 Arg72Pro polymorphism and esophageal cancer (EC) risk using meta-analysis. METHODS:All eligible studies published before March 1, 2010 were selected by searching PubMed using keywords "p53" or "TP53", "polymorphism" or "variation", "esophageal" and "cancer" or "carcinoma...

journal_title：World journal of gastroenterology

authors： Jiang DK,Yao L,Wang WZ,Peng B,Ren WH,Yang XM,Yu L

更新日期：2011-03-07 00:00:00

abstract：AIM:To report a case of severe idiopathic gastroparesis in complete absence of Kit-positive gastric interstitial cells of Cajal (ICC). METHODS:Gastric tissue from a patient with severe idiopathic gastroparesis unresponsive to medical treatment and requiring surgery was analyzed by conventional histology and immunohist...

journal_title：World journal of gastroenterology

authors： Battaglia E,Bassotti G,Bellone G,Dughera L,Serra AM,Chiusa L,Repici A,Mioli P,Emanuelli G

更新日期：2006-10-14 00:00:00

abstract：AIM:To compare the number of regulatory T-cells (Tregs) measured by flow cytometry with those obtained using a real-time quantitative PCR (qPCR) method in patients suffering from inflammatory bowel disease (IBD). METHODS:Tregs percentages obtained by both flow cytometry and qPCR methods in 35 adult IBD patients, 18 ou...

journal_title：World journal of gastroenterology

authors： Brandhorst G,Petrova DT,Weigand S,Eberle C,von Ahsen N,Schmitz J,Schultze FC,Raddatz D,Karaus M,Oellerich M,Walson PD

更新日期：2015-03-21 00:00:00

abstract：AIM:To assess the etiology of chronic liver diseases (CLD) from 1998 to 2014 at the outpatient clinic of Gastroenterology of the main hospital in Northwest of Italy among those dedicated to hepatology. METHODS:A random sample of charts of patients referred to for increased liver enzymes between January 1998 and Decemb...

journal_title：World journal of gastroenterology

authors： Saracco GM,Evangelista A,Fagoonee S,Ciccone G,Bugianesi E,Caviglia GP,Abate ML,Rizzetto M,Pellicano R,Smedile A

更新日期：2016-09-28 00:00:00

abstract：:Despite advances in the management of patients with locally advanced, non-metastatic rectal adenocarcinoma (LARC), prognosis remains largely unsatisfactory due to a high rate of distant relapse. In fact, currently available neoadjuvant protocols, represented by fluoropyrimidine-based chemo-radiotherapy (CT-RT) or shor...

journal_title：World journal of gastroenterology

authors： Fornaro L,Caparello C,Vivaldi C,Rotella V,Musettini G,Falcone A,Baldini E,Masi G

更新日期：2014-05-28 00:00:00

abstract：AIM:To study the expression and serum level of HBxAg, Fas and FasL in tissues of HCC patients, and to assess the relationship between HBxAg and Fas/FasL system. METHODS:Tissues from 50 patients with HCC were tested for the expression of HBxAg, Fas and FasL by S-P immunohistochemistry. Serum levels of sFas/sFasL and HB...

journal_title：World journal of gastroenterology

authors： Wang XZ,Chen XC,Chen YX,Zhang LJ,Li D,Chen FL,Chen ZX,Chen HY,Tao QM

更新日期：2003-12-01 00:00:00

abstract：AIM:To express the complete PreS region of HBV in E.coli with good solubility and stability, and to establish an effective method for purification of the recombinant PreS protein. METHODS:The complete PreS region (PreS1 and PreS2) was fused into a series of tags including glutathione S-transferase (GST), dihydrofolate...

journal_title：World journal of gastroenterology

authors： Deng Q,Kong YY,Xie YH,Wang Y

更新日期：2005-05-28 00:00:00

abstract：:Although the lung is the major site for Mycobacterium tuberculosis infection, gastrointestinal involvement can be present as part of multiorgan disease process or, less commonly, can be seen as primary gastrointestinal tuberculosis. In the cases where the culture is negative, it can be difficult to differentiate tuber...

journal_title：World journal of gastroenterology

authors： Settbas Y,Alper M,Akcan Y,Gurbuz Y,Oksuz S

更新日期：2003-10-01 00:00:00

abstract：AIM:To assess quantitatively the relationship between fish intake and the incidence of gastrointestinal cancers in a meta-analysis of cohort studies. METHODS:We searched MEDLINE, Embase, Science Citation Index Expanded, and the bibliographies of retrieved articles. Prospective cohort studies were included if they repo...

journal_title：World journal of gastroenterology

authors： Yu XF,Zou J,Dong J

更新日期：2014-11-07 00:00:00

abstract：AIM:To explore the transcriptional gene expression profiles of HGF/SF-met signaling pathway in colorectal carcinoma to understand mechanisms of the signaling pathway at so gene level. METHODS:Total RNA was isolated from human colorectal carcinoma cell line LoVo treated with HGF/SF (80 ng/L) for 48 h. Fluorescent probe...

journal_title：World journal of gastroenterology

authors： Li XN,Ding YQ,Liu GB

更新日期：2003-08-01 00:00:00

abstract：:This review is part three of three and will present an update on the therapeutic options and procedures concerning gastrointestinal (GI) submucosal tumors (SMTs). The aim of this paper is to investigate the treatments of GI SMTs and to present a case of a gastrointestinal stromal tumor (GIST). Literature searches were...

journal_title：World journal of gastroenterology

authors： Ponsaing LG,Hansen MB

更新日期：2007-06-28 00:00:00

abstract：:A case of pedunculated Brunner's gland hamartoma (BGH) of the duodenum causing upper gastrointestinal (GI) hemorrhage is reported. The patient was a 47-year-old man who visited our hospital for further evaluation of tarry stools and shortness of breath. Endoscopic examination of the upper digestive tract revealed a la...

journal_title：World journal of gastroenterology

authors： Hirasaki S,Kubo M,Inoue A,Miyake Y,Oshiro H

更新日期：2009-01-21 00:00:00

abstract：AIM:To evaluate the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be avoided. METHODS:A total of 324 patients with celiac disease (CD; 97 children and 227 adults) were recruited prospectively at two tertiary cente...

journal_title：World journal of gastroenterology

authors： Vivas S,Ruiz de Morales JG,Riestra S,Arias L,Fuentes D,Alvarez N,Calleja S,Hernando M,Herrero B,Casqueiro J,Rodrigo L

更新日期：2009-10-14 00:00:00

abstract：:E2F family of transcription factors regulates various cellular functions related to cell cycle and apoptosis. Its individual members have traditionally been classified into activators and repressors, based on in vitro studies. However their contribution in human cancer is more complicated and difficult to predict. We ...

journal_title：World journal of gastroenterology

authors： Xanthoulis A,Tiniakos DG

更新日期：2013-06-07 00:00:00

abstract：AIM:To determine whether circular RNAs (circRNAs) are involved in pathological processes of gastric cancer (GC). METHODS:Three circRNAs with differential expression in GC and colorectal cancer were randomly selected for validation by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), using 20 pair...

journal_title：World journal of gastroenterology

authors： Huang M,He YR,Liang LC,Huang Q,Zhu ZQ

更新日期：2017-09-14 00:00:00

abstract：:Intense abdominal pain is a prominent feature of chronic pancreatitis and its treatment remains a major clinical challenge. Basic studies of pancreatic nerves and experimental human pain research have provided evidence that pain processing is abnormal in these patients and in many cases resembles that seen in neuropat...

journal_title：World journal of gastroenterology

authors： Olesen SS,Juel J,Graversen C,Kolesnikov Y,Wilder-Smith OH,Drewes AM

更新日期：2013-11-14 00:00:00

abstract：AIM:To assess the diagnostic accuracy of endoscopic ultrasound (EUS), fluid tumor markers and cytology in distinguishing benign from (pre)malignant pancreatic cystic lesions. METHODS:46 consecutive patients, referred to a gastroenterologist and surgeon for a symptomatic or incidental pancreatic cyst, were reviewed. EU...

journal_title：World journal of gastroenterology

authors： Aljebreen AM,Romagnuolo J,Perini R,Sutherland F

更新日期：2007-08-07 00:00:00

abstract：AIM:To identify new diagnostic markers and drug targets, the gene expression profiles of pancreatic cancer were compared with that of adjacent normal tissues utilizing cDNA microarray analysis. METHODS:cDNA probes were prepared by labeling mRNA from samples of six pancreatic carcinoma tissues with Cy5-dUTP and mRNA fr...

journal_title：World journal of gastroenterology

authors： Tan ZJ,Hu XG,Cao GS,Tang Y

更新日期：2003-04-01 00:00:00

abstract：AIM:To investigate control of two different types of massive presacral bleeding according to the anatomy of the presacral venous system. METHODS:A retrospective review was performed in 1628 patients with middle or low rectal carcinoma who were treated surgically in the Department of Colorectal Surgery, Changhai Hospit...

journal_title：World journal of gastroenterology

authors： Lou Z,Zhang W,Meng RG,Fu CG

更新日期：2013-07-07 00:00:00

abstract：:We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...

journal_title：World journal of gastroenterology

authors： Díaz R,Aparicio J,Mendizábal A,Faus M,Fleitas T,Aparisi F,Martín M

更新日期：2008-03-28 00:00:00

abstract：:Many patients with Crohn's disease (CD) require surgery. Indications for surgery include failure of medical treatment, bowel obstruction, fistula or abscess formation. The most common surgical procedure is resection. In jejunoileal CD, strictureplasty is an accepted surgical technique that relieves the obstructive sym...

journal_title：World journal of gastroenterology

authors： Yamamoto T,Watanabe T

更新日期：2014-01-07 00:00:00

abstract：BACKGROUND:Epithelioid angiosarcoma is a vascular neoplasm that is among the most aggressive subtypes of sarcomas. Its involvement in the gastrointestinal tract is rare. We here report a case of multifocal gastrointestinal epithelioid angiosarcomas presenting with gastrointestinal bleeding. CASE SUMMARY:A 77-year-old ...

journal_title：World journal of gastroenterology

authors： Chen YW,Dong J,Chen WY,Dai YN

更新日期：2020-08-07 00:00:00

abstract：:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

journal_title：World journal of gastroenterology

authors： Drewes AM,Gregersen H

更新日期：2009-01-14 00:00:00

abstract：AIM:To assess the clinicopathological characteristics of duodenal well-differentiated endocrine tumors. METHODS:We examined clinicopathological characteristics in 11 consecutive patients with duodenal well-differentiated endocrine tumors treated by endoscopic therapy or surgery in our hospital from 1992 through 2007. ...

journal_title：World journal of gastroenterology

authors： Ishido K,Tanabe S,Higuchi K,Sasaki T,Katada C,Azuma M,Naruke A,Koizumi W,Mikami T

更新日期：2010-09-28 00:00:00

abstract：BACKGROUND:Polygonum multiflorum is one of the leading causes of herb-induced liver injury in China. HLA-B*35:01 is reported to be a potential biomarker of Polygonum multiflorum-induced liver injury (PM-DILI). However, little is known about the relationship between single-nucleotide polymorphisms (SNPs) and PM-DILI. A...

journal_title：World journal of gastroenterology

authors： Yang WN,Pang LL,Zhou JY,Qiu YW,Miao L,Wang SY,Liu XZ,Tan KA,Shi WW,Wang GQ,Hou FQ

更新日期：2020-03-28 00:00:00

abstract：AIM:To study the value of colonoscopy and selective angiography in diagnosing ischemic enterocolitis. METHODS:Among the 16 cases under study, 10 cases had hypertension and a history of coronary artery disease (one was hospitalized for sub-ventricular-wall infarction). The blood pressure of 10 of the 16 cases ranged fr...

journal_title：World journal of gastroenterology

authors： He L,Luo HS

更新日期：2005-06-28 00:00:00

abstract：AIM:To investigate the allelic and haplotypic association of reg1alpha gene with tropical calcific pancreatitis (TCP). Since TCP is known to have a variable genetic basis, we investigated the interaction between mutations in the susceptibility genes, SPINK1 and CTSB with reg1alpha polymorphisms. METHODS:We analyzed th...

journal_title：World journal of gastroenterology

authors： Mahurkar S,Bhaskar S,Reddy DN,Rao GV,Chandak GR

更新日期：2007-11-28 00:00:00

abstract：:The bacterial pathogen Helicobacter pylori (H. pylori) colonizes in over half of the world's population. H. pylori that establishes life-long infection in the stomach is definitely associated with gastro-duodenal diseases and a wide variety of non-gastrointestinal tract conditions such as immune thrombocytopenia. Trip...

journal_title：World journal of gastroenterology

authors： Takeuchi H,Trang VT,Morimoto N,Nishida Y,Matsumura Y,Sugiura T

更新日期：2014-07-21 00:00:00

abstract：:Non-invasive predictors of varices in cirrhosis would reduce the need for screening endoscopies. Platelet count and spleen size have been shown to be useful parameters, in mixed groups of cirrhotics with different aetiologies. We evaluated this in two homogeneous groups with cirrhosis due to hepatitis C and alcohol. N...

journal_title：World journal of gastroenterology

authors： Sen S,Griffiths WJ

更新日期：2008-04-21 00:00:00