Transcriptional gene expression profiles of HGF/SF-met signaling pathway in colorectal carcinoma.

abstract：AIM:To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine kinase (SPK) activity is involved in this process. METHODS:Using migration assay, MTT assay and Matrigel assay, the effect of alphastatin on vascular endothelial cells (ECs) was evaluated in vitro. SPK ...

journal_title：World journal of gastroenterology

authors： Chen L,Li T,Li R,Wei B,Peng Z

更新日期：2006-07-14 00:00:00

abstract：AIM:To explore the cooperative effects of antisense oligonucleotide (ASON) of cell adhesion molecules and cimetidine on the expression of E-selectin and ICAM-1 in endothelial cells and their adhesion to tumor cells. METHODS:After treatment of endothelial cells with ASON and/or cimetidine and induction with TNF-alpha, ...

journal_title：World journal of gastroenterology

authors： Tang NH,Chen YL,Wang XQ,Li XJ,Yin FZ,Wang XZ

更新日期：2004-01-01 00:00:00

abstract：:Foreign body ingestion is a common complaint in gastrointestinal clinics. It is usually not difficult to diagnose because most of the patients report a definitive history of accidental foreign body ingestion. However, in rare cases, patients do not have a clear history. Thus, the actual condition of the patient is dif...

journal_title：World journal of gastroenterology

authors： Lu YP,Yao M,Zhou XY,Huang B,Qi WB,Chen ZH,Xu LS

更新日期：2014-10-21 00:00:00

abstract：:Hepatitis C virus (HCV) infection is estimated to affect 130-150 million people globally which corresponds to 2%-3% of the total world population. It remains the leading indication for liver transplant worldwide and has been demonstrated to negatively impact both patient and graft survival following non-hepatic organ ...

journal_title：World journal of gastroenterology

authors： Belga S,Doucette KE

更新日期：2016-01-28 00:00:00

abstract：AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

journal_title：World journal of gastroenterology

authors： Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

更新日期：2014-12-28 00:00:00

abstract：:Gastroparesis has traditionally been a largely medically managed disease with refractory symptoms typically falling under the umbrella of the surgical domain. Surgical options include, but are not limited to, gastrostomy, jejunostomy, pyloromyotomy, or pyloroplasty, and the Food and Drug Administration approved gastri...

journal_title：World journal of gastroenterology

authors： McCarty TR,Rustagi T

更新日期：2015-06-14 00:00:00

abstract：AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor (PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease (GERD) patients. METHODS:Five hundred and seventy seven patients with heartburn were recruited. After completing a psychometri...

journal_title：World journal of gastroenterology

authors： Pace F,Riegler G,de Leone A,Dominici P,Grossi E,EMERGE Study Group.

更新日期：2011-03-07 00:00:00

abstract：AIM:To determine the incidence of Epstein Barr virus associated gastric carcinoma (GC) in Brazil and compare the expressions of apoptosis related proteins and nitric oxide synthases between EBV positive and negative gastric carcinoma. METHODS:In situ hybridization of EBV-encoded small RNA-1 (EBER-1) and PCR was perfor...

journal_title：World journal of gastroenterology

authors： Begnami MD,Montagnini AL,Vettore AL,Nonogaki S,Brait M,Simoes-Sato AY,Seixas AQ,Soares FA

更新日期：2006-08-21 00:00:00

abstract：:Chronic groin pain (Inguinodynia) following inguinal hernia repair is a significant, though under-reported problem. Mild pain lasting for a few days is common following mesh inguinal hernia repair. However, moderate to severe pain persisting more than 3 mo after inguinal herniorrhaphy should be considered as pathologi...

journal_title：World journal of gastroenterology

authors： Hakeem A,Shanmugam V

更新日期：2011-04-14 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated wi...

journal_title：World journal of gastroenterology

authors： Wong F,Rayner-Hartley E,Byrne MF

更新日期：2014-09-14 00:00:00

abstract：AIM:To investigate the toxicity and response of intensity-modulated radiotherapy schedule intensified with a simultaneous integrated boost in anal canal cancer. METHODS:From March 2009 to March 2014, we retrospectively analyzed 41 consecutive patients treated with intensity-modulated radiotherapy (IMRT) and concurrent...

journal_title：World journal of gastroenterology

authors： Belgioia L,Vagge S,Agnese D,Garelli S,Murialdo R,Fornarini G,Chiara S,Gallo F,Bacigalupo A,Corvò R

更新日期：2015-10-07 00:00:00

abstract：:We report a unique case of intramucosal carcinoma in a tubulovillous adenoma arising from a single diverticulum. Endoscopic mucosal resection (EMR) was carried out successfully and completely with the assistance of laparoscopy. A 71-year-old man was admitted to our hospital because of melena and anemia. Emergent colon...

journal_title：World journal of gastroenterology

authors： Fu KI,Hamahata Y,Tsujinaka Y

更新日期：2010-03-28 00:00:00

abstract：:To review the underlying pathophysiology and currently available treatments for pruritis associated with jaundice. English language literature was reviewed using MEDLINE, PubMed, EMBASE and clinicaltrials.gov for papers and trails addressing the pathophysiology and potential treatments for pruritis associated with jau...

journal_title：World journal of gastroenterology

authors： Bassari R,Koea JB

更新日期：2015-02-07 00:00:00

abstract：AIM:To investigate the expression of cancer related genes in gastric carcinoma (GC) through the use of Atlas Human Cancer Array membranes with 588 well-characterized human genes related to cancer and tumor biology. METHODS:Hybridization of cDNA blotting membrane was performed with (32)P-labeled cDNA probes synthesized...

journal_title：World journal of gastroenterology

authors： Liu LX,Liu ZH,Jiang HC,Qu X,Zhang WH,Wu LF,Zhu AL,Wang XQ,Wu M

更新日期：2002-08-01 00:00:00

abstract：:The combination of either boceprevir or telaprevir with ribavirin and interferon (triple therapy) has been shown to be more effective than ribavirin+interferon (dual therapy) for the treatment of genotype 1 hepatitis C. Since the benefit of these treatments takes place after years, simulation models are needed to pred...

journal_title：World journal of gastroenterology

authors： Messori A,Fadda V,Maratea D,Trippoli S

更新日期：2012-06-21 00:00:00

abstract：AIM:To examine the accuracy of the aspartate aminotransferase (AST)/Platelet Ratio Index (APRI) and FIB-4, in predicting longitudinal changes in liver histology in hepatitis C virus (HCV) patients. METHODS:Patients that underwent repeat liver biopsies at least 1 year apart from 1999 to 2007 were identified. Liver fibr...

journal_title：World journal of gastroenterology

authors： Mummadi RR,Petersen JR,Xiao SY,Snyder N

更新日期：2010-12-07 00:00:00

abstract：:The advances of laparoscopic surgery since the early 1990s have caused one of the largest technical revolutions in medicine since the detection of antibiotics (1922, Flemming), the discovery of DNA structure (1953, Watson and Crick), and solid organ transplantation (1954, Murray). Perseverance through a rocky start an...

journal_title：World journal of gastroenterology

authors： Kaiser AM

更新日期：2014-11-07 00:00:00

abstract：AIM:To investigate urotensin-II (UII) and its effects on tumor necrosis factor (TNF)-α and interleukin (IL)-1β in early acute liver failure (ALF). METHODS:We investigated the time-dependent alteration in UII levels and its effects on TNF-α and IL-1β in liver and blood in the early stage of lipopolysaccharide/D-galacto...

journal_title：World journal of gastroenterology

authors： Liu LM,Zhao L,Liang DY,Yu FP,Ye CG,Tu WJ,Zhu T

更新日期：2015-03-21 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the associatio...

journal_title：World journal of gastroenterology

authors： Trifan A,Stanciu C,Girleanu I,Stoica OC,Singeap AM,Maxim R,Chiriac SA,Ciobica A,Boiculese L

更新日期：2017-09-21 00:00:00

abstract：AIM:To evaluate the therapeutic effectiveness of oxaliplatin on human gastric carcinoma and to explore its mechanisms. METHODS:Twenty-two cases of stage IV gastric carcinoma received 4-6 (mean 4.6) cycles of first line combined chemotherapy with oxaliplatin (oxaliplatin 85 mg/m(2), iv, gtt, 1 h, d 1; leukovorin 200 mg...

journal_title：World journal of gastroenterology

authors： Lin WL,Li DG,Chen Q,Lu HM

更新日期：2004-10-01 00:00:00

abstract：AIM:Previous reports have shown that decrease in plasma glutamine (Gln) level following major surgery may contribute to the state of immunosuppression. Gln supplementation improves the depletion of body Gln pool, and may have indirect effect on reducing proinflammatory mediator release. This study evaluated whether the...

journal_title：World journal of gastroenterology

authors： Lin MT,Kung SP,Yeh SL,Liaw KY,Wang MY,Kuo ML,Lee PH,Chen WJ

更新日期：2005-10-21 00:00:00

abstract：BACKGROUND:Lifestyle factors such as body mass index (BMI), alcohol drinking, and cigarette smoking, are likely to impact the prognosis of gastric cancer, but the evidence has been inconsistent. AIM:To investigate the association of lifestyle factors and long-term prognosis of gastric cancer patients in the China Nati...

journal_title：World journal of gastroenterology

authors： Zhao LL,Huang H,Wang Y,Wang TB,Zhou H,Ma FH,Ren H,Niu PH,Zhao DB,Chen YT

更新日期：2020-04-14 00:00:00

abstract：AIM:To investigate the prognostic significance of S100A4 expression in colorectal cancer and its correlation with expression of E-cadherin and p53. METHODS:A cohort of archival formalin-fixed paraffin-embedded specimens was selected from 127 patients with colorectal cancer who underwent surgical resection between Apri...

journal_title：World journal of gastroenterology

authors： Kwak JM,Lee HJ,Kim SH,Kim HK,Mok YJ,Park YT,Choi JS,Moon HY

更新日期：2010-08-21 00:00:00

abstract：AIM:To evaluate the effect of long-term treatment with leukocyte natural α-interferon (ln-α-IFN) plus ribavirin (RBV). METHODS:Forty-six patients with hepatitis C virus (HCV) recurrence received 3 MU three times a week of ln-α-IFN plus RBV for 1 mo; then, patients with good tolerability (n = 30) were switched to daily...

journal_title：World journal of gastroenterology

authors： Tamè M,Buonfiglioli F,Del Gaudio M,Lisotti A,Cecinato P,Colecchia A,Azzaroli F,D'Errico A,Arena R,Calvanese C,Quarneti C,Ballardini G,Pinna AD,Mazzella G

更新日期：2013-08-28 00:00:00

abstract：AIM:To explore the contribution of AXIN1, AXIN2 and beta-catenin, components of Wnt signaling pathway, to the carcinogenesis of gastric cancer (GC), we examined AXIN1, AXIN2 exon7 and CTNNB1 (encoding beta-catenin) exon3 mutations in 70 GCs. METHODS:The presence of mutations was identified by polymerase chain reaction...

journal_title：World journal of gastroenterology

authors： Pan KF,Liu WG,Zhang L,You WC,Lu YY

更新日期：2008-03-14 00:00:00

abstract：:Gastric cancer is the second leading cause of cancer mortality worldwide. The diagnosis of gastric cancer has been significantly improved with the broad availability of gastrointestinal endoscopy. Effective technologies for accurate staging and quantitative evaluation are still in demand to merit reasonable treatment ...

journal_title：World journal of gastroenterology

authors： Wu CX,Zhu ZH

更新日期：2014-04-28 00:00:00

abstract：AIM:To evaluate ATP-binding cassette (ABC) transporters in colonic pathophysiology as they had recently been related to colorectal cancer (CRC) development. METHODS:Literature search was conducted on PubMed using combinations of the following terms: ABC transporters, ATP binding cassette transporter proteins, inflamma...

journal_title：World journal of gastroenterology

authors： Andersen V,Svenningsen K,Knudsen LA,Hansen AK,Holmskov U,Stensballe A,Vogel U

更新日期：2015-11-07 00:00:00

abstract：AIM:To investigate the protective effect and mechanism of rebamipide on small intestinal permeability induced by diclofenac in mice. METHODS:Diclofenac (2.5 mg/kg) was administered once daily for 3 d orally. A control group received the vehicle by gavage. Rebamipide (100 mg/kg, 200 mg/kg, 400 mg/kg) was administered i...

journal_title：World journal of gastroenterology

authors： Diao L,Mei Q,Xu JM,Liu XC,Hu J,Jin J,Yao Q,Chen ML

更新日期：2012-03-14 00:00:00

abstract：AIM:To investigate the influence of remote ischemic preconditioning (RIPC) on anastomotic integrity. METHODS:Sixty male Wistar rats were randomized to six groups. The control group (n = 10) had an end-to-end ileal anastomosis without RIPC. The preconditioned groups (n = 34) varied in time of ischemia and time of reper...

journal_title：World journal of gastroenterology

authors： Holzner PA,Kulemann B,Kuesters S,Timme S,Hoeppner J,Hopt UT,Marjanovic G

更新日期：2011-03-14 00:00:00

abstract：AIM:To determine the incidence of peripheral fractures in patients with celiac disease (CD) and the effect of treatment on fracture risk. METHODS:We compared the incidence and risk of peripheral fractures before and after diagnosis between a cohort of 265 patients who had been diagnosed with CD at least 5 years before...

journal_title：World journal of gastroenterology

authors： Sánchez MI,Mohaidle A,Baistrocchi A,Matoso D,Vázquez H,González A,Mazure R,Maffei E,Ferrari G,Smecuol E,Crivelli A,de Paula JA,Gómez JC,Pedreira S,Mauriño E,Bai JC

更新日期：2011-07-07 00:00:00