Surgery for luminal Crohn's disease.

abstract：AIM:To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As₂O₃); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2. METHODS:Twenty patients with gastrointestin...

journal_title：World journal of gastroenterology

authors： Ma ZB,Xu HY,Jiang M,Yang YL,Liu LX,Li YH

更新日期：2014-05-14 00:00:00

abstract：:Lipoma is relatively common in the colon but is less often in the small intestine. Most lipomas are incidentally detected at endoscopy and are usually small and asymptomatic. However, some of them can present with obstruction and/or intussusceptions. Surgical resection is commonly recommended to remove such significan...

journal_title：World journal of gastroenterology

authors： Morimoto T,Fu KI,Konuma H,Izumi Y,Matsuyama S,Ogura K,Miyazaki A,Watanabe S

更新日期：2010-04-07 00:00:00

abstract：AIM:Because of a major resistance to chemotherapy, prognosis of hepatocellular carcinoma (HCC) is still poor. New treatments are required and gene therapy may be an option. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in multiple malignant tumors, and using adenoviral vectors has sh...

journal_title：World journal of gastroenterology

authors： Jacob D,Schumacher G,Bahra M,Davis J,Zhu HB,Zhang LD,Teraishi F,Neuhaus P,Fang BL

更新日期：2005-05-07 00:00:00

abstract：:Colorectal cancer hepatic metastases represent the final stage of a multi-step biological process. This process starts with a series of mutations in colonic epithelial cells, continues with their detachment from the large intestine, dissemination through the blood and/or lymphatic circulation, attachment to the hepati...

journal_title：World journal of gastroenterology

authors： Paschos KA,Majeed AW,Bird NC

更新日期：2014-04-14 00:00:00

abstract：AIM:To investigate the distribution pattern of lymphatic vessels and microvessels in sporadic colorectal carcinoma (SCRC) and their relationship to metastasis and prognosis. METHODS:The lymphatic vessel density (LVD) and microvessel density (MVD) in tumor tissue obtained from 132 patients with primary SCRC, including ...

journal_title：World journal of gastroenterology

authors： Yan G,Zhou XY,Cai SJ,Zhang GH,Peng JJ,Du X

更新日期：2008-01-07 00:00:00

abstract：:Erythropoietic protoporphyria (EPP) is an extremely rare disease which is often unrecognized as diagnosis. In the recent article Lui et al describe a patient with a new diagnosis of EPP with severe liver injury. Approximately 5%-20% of patients with EPP develop liver manifestations. The most severe complication of EPP...

journal_title：World journal of gastroenterology

authors： Wensink D,Wagenmakers MA,Wilson JP,Langendonk JG

更新日期：2019-08-14 00:00:00

abstract：:Henry Norman Bethune was a physician and surgeon from Canada. He had a highly impressive medical career in Montreal but did his most important work in China where he cared for soldiers on the battlefield. He died in 1939 and was recognized as a hero, but only much later received recognition in Canada. He was a skilled...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2008-01-14 00:00:00

abstract：:Viable and non-viable pathological bacterial translocation promote a self-perpetuating circle of dysfunctional immune activation and systemic inflammation facilitating infections and organ failure in advanced cirrhosis. Bacterial infections and sepsis are now recognized as a distinct stage in the natural progression o...

journal_title：World journal of gastroenterology

authors： Bruns T,Zimmermann HW,Stallmach A

更新日期：2014-03-14 00:00:00

abstract：AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy. METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre, were rev...

journal_title：World journal of gastroenterology

authors： Pang TC,Fung T,Samra J,Hugh TJ,Smith RC

更新日期：2011-03-28 00:00:00

abstract：:Multiple robotic flexible endoscope platforms have been developed based on cross specialty collaboration between engineers and medical doctors. However, significant number of these platforms have been developed for the natural orifice transluminal endoscopic surgery paradigm. Increasing amount of evidence suggest the ...

journal_title：World journal of gastroenterology

authors： Yeung BP,Chiu PW

更新日期：2016-02-07 00:00:00

abstract：:Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the pathogenesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present sys...

journal_title：World journal of gastroenterology

authors： Salari P,Abdollahi M

更新日期：2011-10-14 00:00:00

abstract：AIM:To investigated the effects of urotensin II (UII) on hepatic insulin resistance in HepG2 cells and the potential mechanisms involved. METHODS:Human hepatoma HepG2 cells were cultured with or without exogenous UII for 24 h, in the presence or absence of 100 nmol/L insulin for the last 30 min. Glucose levels were de...

journal_title：World journal of gastroenterology

authors： Li YY,Shi ZM,Yu XY,Feng P,Wang XJ

更新日期：2016-07-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) remains to be one of the top causing cancer-related deaths today. The majority of HCC cases are reported to be the result of chronic hepatitis B virus (HBV) infection. Current treatments for HBV-related HCC revolve around the use of drugs to inhibit viral replication, as a high level of ...

journal_title：World journal of gastroenterology

authors： Tan YL,Chen WN

更新日期：2014-05-28 00:00:00

abstract：AIM:To investigate the acute toxicity, phytochemical profile, antidiarrheal activity and mechanisms of action of Maytenus erythroxylon (M. erythroxylon) ethanol extract. METHODS:A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity. Intestinal transit and gastric emptying protocols were used ...

journal_title：World journal of gastroenterology

authors： Formiga RO,Quirino ZGM,Diniz MFFM,Marinho AF,Tavares JF,Batista LM

更新日期：2017-06-28 00:00:00

abstract：AIM:To investigate the underlying molecular mechanisms of miR-451 to inhibit proliferation of esophageal carcinoma cell line EC9706. METHODS:Assays for cell growth, apoptosis and invasion were used to evaluate the effects of miR-451 expression on EC cells. Luciferase reporter and Western blot assays were used to test ...

journal_title：World journal of gastroenterology

authors： Zang WQ,Yang X,Wang T,Wang YY,Du YW,Chen XN,Li M,Zhao GQ

更新日期：2015-05-21 00:00:00

abstract：AIM:To clarify the role of neoadjuvant concurrent chemoradiotherapy (NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma (CCA). METHODS:We retrospectively reviewed 57 patients who underwent surgical resection with or without NACCRT for perihilar CCA; 12 patients receiv...

journal_title：World journal of gastroenterology

authors： Jung JH,Lee HJ,Lee HS,Jo JH,Cho IR,Chung MJ,Park JY,Park SW,Song SY,Bang S

更新日期：2017-05-14 00:00:00

abstract：AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

journal_title：World journal of gastroenterology

authors： Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

更新日期：2002-02-01 00:00:00

abstract：AIM:To compare the antisecretory activity and plasma drug concentrations of a single oral dose of 10 mg lafutidine, a novel H2 receptor antagonist, with those of the proton pump inhibitor lansoprazole (LPZ) 30 mg. METHODS:Ten volunteers without H pylori infection participated in this crossover study comparing lafutidi...

journal_title：World journal of gastroenterology

authors： Yamagishi H,Koike T,Ohara S,Horii T,Kikuchi R,Kobayashi S,Abe Y,Iijima K,Imatani A,Suzuki K,Hishinuma T,Goto J,Shimosegawa T

更新日期：2008-04-21 00:00:00

abstract：BACKGROUND:Accumulating evidence has revealed that several long non-coding ribonucleic acids (lncRNAs) are crucial in the progress of hepatocellular carcinoma (HCC). AIM:To classify a long non-coding RNA, i.e., lncRNA W5, and to determine the clinical significance and potential roles of lncRNA W5 in HCC. METHODS:The ...

journal_title：World journal of gastroenterology

authors： Lei GL,Fan HX,Wang C,Niu Y,Li TL,Yu LX,Hong ZX,Yan J,Wang XL,Zhang SG,Ren MJ,Yang PH

更新日期：2021-01-07 00:00:00

abstract：:Inflammatory bowel disease (IBD) is associated with increased risk of colorectal cancer (CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the h...

journal_title：World journal of gastroenterology

authors： Althumairi AA,Lazarev MG,Gearhart SL

更新日期：2016-01-21 00:00:00

abstract：:P21-activated kinases (PAKs) are central players in various oncogenic signaling pathways. The six PAK family members are classified into group I (PAK1-3) and group II (PAK4-6). Focus is currently shifting from group I PAKs to group II PAKs. Group II PAKs play important roles in many fundamental cellular processes, som...

journal_title：World journal of gastroenterology

authors： Shao YG,Ning K,Li F

更新日期：2016-01-21 00:00:00

abstract：AIM:To identify the differentially over-expressed genes associated with β-catenin accumulation in nuclei of hepatocellular carcinoma (HCC) cells. METHODS:Differentially expressed genes were identified in radiation-induced B6C3 F1 mouse HCC cells by mRNA differential display, Northern blot and RT-PCR, respectively. Tot...

journal_title：World journal of gastroenterology

authors： Li YS,Liu M,Nakata Y,Tang HB

更新日期：2011-04-07 00:00:00

abstract：AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors (EGISTs) in South Korea. METHODS:A total of 51 patients with an EGIST were identified. The clinicopathologic features, including sex, age, location, tumor size, histology, mitotic rate, immunohistochemical features...

journal_title：World journal of gastroenterology

authors： Yi JH,Park BB,Kang JH,Hwang IG,Shin DB,Sym SJ,Ahn HK,Lee SI,Lim DH,Park KW,Won YW,Lim SH,Park SH

更新日期：2015-02-14 00:00:00

abstract：AIM:The prognosis of early gastric carcinoma (EGC) is generally excellent after surgery. The presence or absence of lymph node metastasis in EGC is an important prognostic factor. The survival and recurrence rates of node-negative EGC are much better than those of node-positive EGC. This study examined the factors rela...

journal_title：World journal of gastroenterology

authors： Kim DY,Joo JK,Ryu SY,Kim YJ,Kim SK

更新日期：2004-03-01 00:00:00

abstract：AIM:To investigate the effect of bone marrow-derived monocytes transfected with RNA of CT-26 (a cell line of mouse colon carcinoma) on antitumor immunity. METHODS:Mouse bone marrow-derived monocytes were incubated with mouse granulocyte macrophage colony stimulating factor (mGM-CSF) in vitro, and the purity of monocyt...

journal_title：World journal of gastroenterology

authors： Chu XY,Chen LB,Zang J,Wang JH,Zhang Q,Geng HC

更新日期：2005-02-07 00:00:00

abstract：AIM:To globally compare the gene expression profiles during the capillary morphogenesis of human microvascular endothelial cells (HMVECs) in an in vitro angiogenesis system with affymetrix oligonucleotide array. METHODS:A microcarrier-based in vitro angiogenesis system was developed, in which ECs migrated into the mat...

journal_title：World journal of gastroenterology

authors： Sun XT,Zhang MY,Shu C,Li Q,Yan XG,Cheng N,Qiu YD,Ding YT

更新日期：2005-04-21 00:00:00

abstract：:Peliosis hepatis is a rare benign disease, but in last years the number of identified cases has increased. This disease is known to be sometimes accompanied by hepatocellular carcinoma. In the recent article, Yu et al describe a case of liver peliosis, characterized by an increased proliferative index. Therefore, addi...

journal_title：World journal of gastroenterology

authors： Demyashkin G,Zatsepina M

更新日期：2020-09-14 00:00:00

abstract：:Malignant gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors originating from the wall of the gastrointestinal tract. Their coexistence with other tumors originating from other germ layers is unique. We have reported a case of a 63-year-old GIST patient presenting as an epigastric mass associated with ...

journal_title：World journal of gastroenterology

authors： Jaworski R,Jastrzebski T,Swierblewski M,Drucis K,Kobierska-Gulida G

更新日期：2006-01-28 00:00:00

abstract：AIM:To investigate DNA ploidy and expression of MMP-9, TIMP-2, and E-cadherin in gastric carcinoma and to explore the mechanism of invasion and metastasis of gastric carcinoma. METHODS:Immunohistochemical methods were used to detect the expressions of MMP-9, TIMP-2, and E-cadherin in 156 cases, including 99 cases of g...

journal_title：World journal of gastroenterology

authors： Zhang JF,Zhang YP,Hao FY,Zhang CX,Li YJ,Ji XR

更新日期：2005-09-28 00:00:00

abstract：:Recently, the use of confocal laser endomicroscopy (CLE) in the diagnosis of chronic ulcerative colitis (CUC) was reported. In this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in CUC. The study involved a patient presenting long-standing CUC. Confocal...

journal_title：World journal of gastroenterology

authors： De Palma GD,Staibano S,Siciliano S,Maione F,Siano M,Esposito D,Persico G

更新日期：2011-02-07 00:00:00