Inflammatory bowel disease associated neoplasia: A surgeon's perspective.

Abstract:

:Inflammatory bowel disease (IBD) is associated with increased risk of colorectal cancer (CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the heterogeneous endoscopic appearance and inter-observer variability of the pathological diagnosis. Screening and surveillance guidelines have been established which aim for early detection of neoplasia. Several surgical options are available for the treatment of IBD-associated neoplasia. Patients' morbidities, risk factors for CRC, degree and the extent of neoplasia must be considered in choosing the surgical treatment. A multidisciplinary team including the surgeon, gastroenterologist, pathologist, and the patient who has a clear understanding of the nature of their disease is needed to optimize outcomes.

journal_name

World J Gastroenterol

authors

Althumairi AA,Lazarev MG,Gearhart SL

doi

10.3748/wjg.v22.i3.961

subject

Has Abstract

pub_date

2016-01-21 00:00:00

pages

961-73

issue

3

eissn

1007-9327

issn

2219-2840

journal_volume

22

pub_type

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