Modified technique for combined liver-small bowel transplantation in pigs.

Abstract:

AIM:As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in pigs. METHODS:Composite liver/small bowel allotransplantations were undertaken in 30 long-white pigs. The graft included liver, about 3 to 4 m proximal jejunum, duodenum and partial pancreatic head. Vessels reconstructions included subhepatic vena cava-vena cava anastomosis, aorta-aorta anastomosis and portal-splenic vein anastomosis. RESULTS:Without immunosuppressive treatment, the median survival time of the animals was 6 days (2 to 12 days), and about 76.9 % (20/26) of the animals survived for more than 4 days after operation. CONCLUSION:The modified technique is feasible and safe for the composite liver/small bowel transplantation with duodenum and pancreas preserved in pigs. And also this technique can simplify the operation and decrease possible postoperative complications.

journal_name

World J Gastroenterol

authors

Yin ZY,Ni XD,Jiang F,Li N,Li YS,Li JS

doi

10.3748/wjg.v9.i7.1625

keywords:

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

1625-8

issue

7

eissn

1007-9327

issn

2219-2840

journal_volume

9

pub_type

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