Assessment of liver fibrosis by Fibroscan as compared to liver biopsy in biliary atresia.

abstract：:AIM:To determine whether recombinant human epidermal growth factor (rhEGF) can protect gastric mucosa against ethanol induced injury in rats.METHOD: Fifty-four SD rats weighing 200g-500g each were divided into six groups after fasting for 24 hours.Three groups received different doses of oral rhEGF (30, 60 and 120&mgr...

journal_title：World journal of gastroenterology

authors： Xu CD,Gan RB,Chen SN,Jiang SH,Xu JY

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is a common chronic non-organic disease of the digestive system. Berberine (BBR) has been used to treat patients with IBS, but the underlying therapeutic mechanism is little understood. We believe that BBR achieves its therapeutic effect on IBS by preventing stress intestinal i...

journal_title：World journal of gastroenterology

authors： Yu ZC,Cen YX,Wu BH,Wei C,Xiong F,Li DF,Liu TT,Luo MH,Guo LL,Li YX,Wang LS,Wang JY,Yao J

更新日期：2019-08-07 00:00:00

abstract：AIM:To assess whether trace metal concentrations (which influence metabolism as both essential and non-essential elements) are increased or decreased in cancerous tissues and to understand the precise role of these metals in carcinogenesis. METHODS:Concentrations of trace metals including Cd, Ni, Cu, Zn, Fe, Mg and Ca...

journal_title：World journal of gastroenterology

authors： Yaman M,Kaya G,Yekeler H

更新日期：2007-01-28 00:00:00

abstract：AIM:To determine the upper cut-off values of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in a Northern Chinese population. METHODS:A total of 3769 subjects in Jilin Province Northeast China were stratified to determine the potential factors affecting serum ALT and AST levels. The upper cu...

journal_title：World journal of gastroenterology

authors： Zhang P,Wang CY,Li YX,Pan Y,Niu JQ,He SM

更新日期：2015-02-28 00:00:00

abstract：AIM:To determine the efficacy profiles of different concentrations of Lactobacillus acidophilus (L. acidophilus) for treating colitis using an experimental murine model. METHODS:Colitis was established in 64 BALB/c mice by adding 5% dextran sodium sulfate (DSS) to the drinking water and allowing ad libitum access for ...

journal_title：World journal of gastroenterology

authors： Chen LL,Zou YY,Lu FG,Li FJ,Lian GH

更新日期：2013-08-28 00:00:00

abstract：AIM:To validate the clinical Rockall score in predicting outcomes (rebleeding, surgery and mortality) in elderly patients with acute upper gastrointestinal bleeding (AUGIB). METHODS:A retrospective analysis was undertaken in 341 patients admitted to the emergency room and Intensive Care Unit of Xuanwu Hospital of Capi...

journal_title：World journal of gastroenterology

authors： Wang CY,Qin J,Wang J,Sun CY,Cao T,Zhu DD

更新日期：2013-06-14 00:00:00

abstract：:Multiple robotic flexible endoscope platforms have been developed based on cross specialty collaboration between engineers and medical doctors. However, significant number of these platforms have been developed for the natural orifice transluminal endoscopic surgery paradigm. Increasing amount of evidence suggest the ...

journal_title：World journal of gastroenterology

authors： Yeung BP,Chiu PW

更新日期：2016-02-07 00:00:00

abstract：AIM:To explore the mechanism for interactions of leptin with ghrelin and orexin in the arcuate nucleus (ARC) activating neuropeptide Y (NPY) neurons during physiological regulation of feeding. METHODS:Single neurons from ARC of adult rats with matured feeding function were isolated. [Ca2+]i was measured to monitor the...

journal_title：World journal of gastroenterology

authors： Kohno D,Suyama S,Yada T

更新日期：2008-11-07 00:00:00

abstract：:The optimal method for monitoring quiescent disease in patients with Crohn's disease (CD) and ulcerative colitis is yet to be determined. Endoscopic evaluation with ileocolonoscopy is the gold standard but is invasive, costly, and time-consuming. There are many commercially available biomarkers that may be used in cli...

journal_title：World journal of gastroenterology

authors： Chang S,Malter L,Hudesman D

更新日期：2015-10-28 00:00:00

abstract：AIM:To determine whether any changes have occurred on the patterns of colorectal cancer in China. METHODS:Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology...

journal_title：World journal of gastroenterology

authors： Li M,Gu J

更新日期：2005-08-14 00:00:00

abstract：:AIM:To study the peripheral mechanism of the inhibitory effect of intra-third ventricular administration (icv) of histamine (HA) on gastric acid secretion in rats.METHODS:Gastric acid was continuously washed with 37&mgr; saline by a perfusion pump in male adrenalectomized SD rats. Drugs were injected intravenously (iv...

journal_title：World journal of gastroenterology

authors： Zhang ZF,Wang ZL,Lu GQ

更新日期：1998-06-01 00:00:00

abstract：AIM:To examine the association between obesity-related adipokines (adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) and colorectal cancer (CRC) risk. METHODS:Serum levels of adipokines were measured in 100 CRC patients and age- and sex-matched controls for the data analysis. Unc...

journal_title：World journal of gastroenterology

authors： Joshi RK,Kim WJ,Lee SA

更新日期：2014-06-28 00:00:00

abstract：AIM:To investigate the inhibitory effect of in vivo expression of expressing plasmid pCH510 of recombinant fibronectin polypeptide (CH50) on hepatocellular carcinoma and the improved therapeutic effect of pCH510 in combination with chemotherapeutic agents and Hsp70-H22 hepatocarcinoma antigen peptide on tumor. METHODS...

journal_title：World journal of gastroenterology

authors： Zhang GM,Yang Y,Huang B,Xiao H,Li D,Feng ZH

更新日期：2003-09-01 00:00:00

abstract：:Liver injury is a characteristic feature of human immunodeficiency virus (HIV) infection, which is the second most common cause of mortality in HIV-infected patients. Now it is recognized that liver plays a key role in HIV infection pathogenesis. Antiretroviral therapy (ART), which suppresses HIV infection in permissi...

journal_title：World journal of gastroenterology

authors： Ganesan M,Poluektova LY,Kharbanda KK,Osna NA

更新日期：2018-11-14 00:00:00

abstract：AIM:To study the association between hilar cholangiocarcinoma (HC) and pre-existing medical conditions. METHODS:Three hundred and thirteen HC patients admitted to the Eastern Hepatobiliary Surgery Hospital (Shanghai, China) in 2000-2005 and 608 healthy controls were enrolled in this study. Association between HC and p...

journal_title：World journal of gastroenterology

authors： Cai WK,Sima H,Chen BD,Yang GS

更新日期：2011-01-14 00:00:00

abstract：:AIM:To prepare valaciclovir polybutylcyan_oacrylate nanoparticles (VACV-PBCA-NP) with liver targeting and hepatocyte permeable charateristics.METHODS: Emulsion polymerization method was employed to prepare VACV-PBCA-NP.The formula and preparation conditions were optimized by using the uniform design. The organ distrib...

journal_title：World journal of gastroenterology

authors： Zhang ZR,He Q

更新日期：1999-08-01 00:00:00

abstract：:A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99...

journal_title：World journal of gastroenterology

authors： Sano S,Yamagami K,Tanaka A,Nishio M,Nakamura T,Kubo Y,Inoue T,Ueda W,Okawa K,Yoshioka K

更新日期：2008-10-21 00:00:00

abstract：AIM:Small intestinal bacterial overgrowth (SIBO) may contribute to the appearance of several gastrointestinal nonspecific symptoms. Acute diverticulitis is affected by some similar symptoms and bacterial colonic overgrowth. We assessed the prevalence of SIBO in acute uncomplicated diverticulitis and evaluated its influ...

journal_title：World journal of gastroenterology

authors： Tursi A,Brandimarte G,Giorgetti GM,Elisei W

更新日期：2005-05-14 00:00:00

abstract：AIM:To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS:We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tumours in nude mice. Th...

journal_title：World journal of gastroenterology

authors： Kunanopparat A,Issara-Amphorn J,Leelahavanichkul A,Sanpavat A,Patumraj S,Tangkijvanich P,Palaga T,Hirankarn N

更新日期：2018-09-14 00:00:00

abstract：AIM:To study the origin of calcium necessary for agonist-induced contraction of the distal colon in rats. METHODS:The change in intracellular calcium concentration ([Ca2+]i) evoked by elevating external Ca2+ was detected by fura 2/AM fluorescence. Contractile activity was measured with a force displacement transducer....

journal_title：World journal of gastroenterology

authors： Zhou H,Kong DH,Pan QW,Wang HH

更新日期：2008-02-21 00:00:00

abstract：AIM:To investigate the role of nuclear factor-kappaB (NF-kappaB) inhibitor caffeic acid phenethy1 ester (CAPE) in the proliferation, collagen synthesis and apoptosis of hepatic stellate cells (HSCs) of rats. METHODS:The HSCs from rats were isolated and cultured in Dulbecco's Modified Eagle's Medium (DMEM) and treated ...

journal_title：World journal of gastroenterology

authors： Zhao WX,Zhao J,Liang CL,Zhao B,Pang RQ,Pan XH

更新日期：2003-06-01 00:00:00

abstract：:In the last decade trans-arterial radioembolization has given promising results in the treatment of patients with intermediate or advanced stage hepatocellular carcinoma (HCC), both in terms of disease control and tolerability profile. This technique consists of the selective intra-arterial administration of microsphe...

journal_title：World journal of gastroenterology

authors： Sacco R,Mismas V,Marceglia S,Romano A,Giacomelli L,Bertini M,Federici G,Metrangolo S,Parisi G,Tumino E,Bresci G,Corti A,Tredici M,Piccinno M,Giorgi L,Bartolozzi C,Bargellini I

更新日期：2015-06-07 00:00:00

abstract：AIM:To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines. METHODS:Gastric lesions were produced by oral gavage of aspirin (200 mg/kg) and HCl (0.15 mol/...

journal_title：World journal of gastroenterology

authors： Odashima M,Otaka M,Jin M,Komatsu K,Wada I,Horikawa Y,Matsuhashi T,Hatakeyama N,Oyake J,Ohba R,Watanabe S,Linden J

更新日期：2006-01-28 00:00:00

abstract：:Liver penetration is a rare but serious complication of peptic ulcer disease. Usually the diagnosis is made by operation or autopsy. Clinical and laboratory data were no specific. A 64-year-old man was admitted with upper gastrointestinal bleeding. Hepatic penetration was diagnosed as the cause of bleeding. Endoscopy ...

journal_title：World journal of gastroenterology

authors： Kayacetin E,Kayacetin S

更新日期：2004-06-15 00:00:00

abstract：:AIM:To investigate the expression of somatostatin mRNA in various differentiated types of gastric carcinoma.METHODS: By using in situ hybridization and immunohistochemical techniques, the expression of somatostatin mRNA and somatostatin immunoreactivity in the normal gastric mucosa, the poorly, moderately and well-dif...

journal_title：World journal of gastroenterology

authors： Zhang QX,Dou YL,Shi XY,Ding Y

更新日期：1998-02-01 00:00:00

abstract：AIM:To assess the role of three-dimensional endoanal ultrasound (3D-EAUS) for morphological assessment of the anal sphincter of female patients with chronic proctalgia (CP). METHODS:In this unmatched case control study, 30 consecutive female patients with CP and 25 normal women (control group) were enrolled. 3D-EAUS w...

journal_title：World journal of gastroenterology

authors： Xue YH,Ding SQ,Ding YJ,Pan LQ

更新日期：2017-06-07 00:00:00

abstract：AIM:To compare the clinical outcomes between jejunal interposition reconstruction and Roux-en-Y anastomosis after total gastrostomy in patients with gastric cancer. METHODS:A systematic literature search was conducted by two independent researchers on PubMed, EMBASE, the Cochrane Library, Google Scholar, and other Eng...

journal_title：World journal of gastroenterology

authors： Fan KX,Xu ZF,Wang MR,Li DT,Yang XS,Guo J

更新日期：2015-03-14 00:00:00

abstract：AIM:To evaluate the serum concentration of antimitochondrial antibodies (AMAs) as a prognostic indicator of progressive primary biliary cirrhosis (pPBC). METHODS:Serum concentrations of AMA subtypes (anti-M2, anti-M4, and anti-M9), biochemical indices of liver function and Mayo risk factor (MRF) were determined in 30 ...

journal_title：World journal of gastroenterology

authors： Flisiak R,Pelszynska M,Prokopowicz D,Rogalska M,Grygoruk U

更新日期：2005-09-28 00:00:00

abstract：AIM:To retrospectively collect inpatient and outpatient data and to assess the use of endoscopic procedures during the years 1991, 1997 and 2003 to analyse for trends. METHODS:This retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary health care services f...

journal_title：World journal of gastroenterology

authors： Schultz M,Davidson A,Donald S,Targonska B,Turnbull A,Weggery S,Livingstone V,Dockerty JD

更新日期：2009-02-07 00:00:00

abstract：:The patient with inflammatory bowel disease will be predisposed to numerous infections due their immune status. It is therefore important to understand the immune and serologic status at diagnosis and to put the patient into an adapted vaccination program. This program would be applied differently according to two pat...

journal_title：World journal of gastroenterology

authors： Sánchez-Tembleque MD,Corella C,Pérez-Calle JL

更新日期：2013-03-07 00:00:00