Changing patterns of colorectal cancer in China over a period of 20 years.

abstract：:An estimated 300 million people worldwide suffer from chronic hepatitis C with a prevalence of 0.8%-1.0% of the general population in Canada. An increasing pool of evidence exists supporting the use of pegylated- interferon (pegIFN) and ribavirin combination therapy for hepatitis C. We report a 49-year old male of Nor...

journal_title：World journal of gastroenterology

authors： Zandieh I,Adenwalla M,Cheong-Lee C,Ma PE,Yoshida EM

更新日期：2006-08-14 00:00:00

abstract：AIM:To investigate whether continuous veno-venous hemofiltration (CVVH) in different filtration rate to eliminate cytokines would result in different efficiency in acute pancreatitis, whether the saturation time of filter membrane was related to different filtration rate, and whether the onset time of CVVH could influe...

journal_title：World journal of gastroenterology

authors： Jiang HL,Xue WJ,Li DQ,Yin AP,Xin X,Li CM,Gao JL

更新日期：2005-08-21 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients' quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant...

journal_title：World journal of gastroenterology

authors： Lazaraki G,Chatzimavroudis G,Katsinelos P

更新日期：2014-07-21 00:00:00

abstract：AIM:To clarify the biological feature contributing to gastric cancer with diffuse bone metastases at diagnosis. METHODS:The participants visited the Department of Clinical Oncology, Akita University Hospital, from January 2014 to August 2015. The selection criterion for gastric cancer with diffuse bone metastases at d...

journal_title：World journal of gastroenterology

authors： Shimazu K,Fukuda K,Yoshida T,Inoue M,Shibata H

更新日期：2016-07-14 00:00:00

abstract：:Anti-tumour necrosis factor α (anti-TNFα) therapy is an established treatment in inflammatory bowel disease. However, this treatment is associated with high costs and the possibility of severe adverse events representing a true challenge for patients, clinicians and health care systems. Consequently, a crucial questio...

journal_title：World journal of gastroenterology

authors： Papamichael K,Vermeire S

更新日期：2015-04-28 00:00:00

abstract：:In their seminal papers Hanahan and Weinberg described oncogenic processes a normal cell undergoes to be transformed into a cancer cell. The functions of ion channels in the gastrointestinal (GI) tract influence a variety of cellular processes, many of which overlap with these hallmarks of cancer. In this review we fo...

journal_title：World journal of gastroenterology

authors： Anderson KJ,Cormier RT,Scott PM

更新日期：2019-10-14 00:00:00

abstract：AIM:Hepatitis B virus (HBV) re-activation often occurs spontaneously or after withdrawal of immunosuppressive therapy in patients with chronic hepatitis B. Severe exacerbation, sometimes developing into fulminant hepatic failure, is at high risk of mortality. The efficacy of corticosteroid therapy in "clinically severe...

journal_title：World journal of gastroenterology

authors： Fujiwara K,Yokosuka O,Kojima H,Kanda T,Saisho H,Hirasawa H,Suzuki H

更新日期：2005-02-28 00:00:00

abstract：:Bone metastases from gastric cancer (GC) are considered a relatively uncommon finding; however, they are related to poorer prognosis. Both primary GC and its metastatic progression rely on angiogenesis. Several lines of evidence from GC patients strongly support the involvement of mast cells (MCs) positive to tryptase...

journal_title：World journal of gastroenterology

authors： Leporini C,Ammendola M,Marech I,Sammarco G,Sacco R,Gadaleta CD,Oakley C,Russo E,De Sarro G,Ranieri G

更新日期：2015-10-07 00:00:00

abstract：AIM:To evaluate retrospectively the correlation between enhancement patterns on dynamic computed tomography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma. METHODS:Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative en...

journal_title：World journal of gastroenterology

authors： Hattori Y,Gabata T,Matsui O,Mochizuki K,Kitagawa H,Kayahara M,Ohta T,Nakanuma Y

更新日期：2009-07-07 00:00:00

abstract：AIM:To investigate an association between N-acetyltransferase 2 (NAT2)-haplotypes/diplotypes and adverse effects in Japanese pulmonary tuberculosis patients. METHODS:We studied 100 patients with pulmonary TB treated with anti-TB drugs including INH. The frequencies and distributions of single nucleotide polymorphisms,...

journal_title：World journal of gastroenterology

authors： Higuchi N,Tahara N,Yanagihara K,Fukushima K,Suyama N,Inoue Y,Miyazaki Y,Kobayashi T,Yoshiura K,Niikawa N,Wen CY,Isomoto H,Shikuwa S,Omagari K,Mizuta Y,Kohno S,Tsukamoto K

更新日期：2007-12-07 00:00:00

abstract：AIM:To evaluate the effects of diazoxide on ischemia/reperfusion (I/R)-injured hepatocytes and further elucidate its underlying mechanisms. METHODS:Male Sprague-Dawley rats were randomized (8 for donor and recipient per group) into five groups: I/R group (4 h of liver cold ischemia followed by 6 h of reperfusion); hem...

journal_title：World journal of gastroenterology

authors： Zeng Z,Huang HF,He F,Wu LX,Lin J,Chen MQ

更新日期：2012-04-21 00:00:00

abstract：AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

journal_title：World journal of gastroenterology

authors： Tan YW,Zhou XB,Ye Y,He C,Ge GH

更新日期：2017-08-21 00:00:00

abstract：AIM:Clinical and experimental data suggest that gut-derived endotoxins are an important pathogenic factors for progression of chronic liver disease. Recently, a C-T (-159) polymorphism in the promoter region of the CD14 gene was detected and found to confer increased CD14 expression and to be associated with advanced a...

journal_title：World journal of gastroenterology

authors： Meiler C,Muhlbauer M,Johann M,Hartmann A,Schnabl B,Wodarz N,Schmitz G,Scholmerich J,Hellerbrand C

更新日期：2005-10-14 00:00:00

abstract：:Pegylated interferon (IFN) α-2a or 2b in combination with ribavirin for children aged 3 years and older is the standard treatment for paediatric chronic hepatitis C. This treatment regimen was developed firstly in adults. In recent years, a number of direct-acting antiviral agents (DAAs) are under development for trea...

journal_title：World journal of gastroenterology

authors： Serranti D,Indolfi G,Resti M

更新日期：2014-11-21 00:00:00

abstract：AIM:To investigate the relationship between the expression of p16 gene and the gastric carcinogenesis, depth of invasion and lymph node metastases, and to evaluate the deletion and mutation of exon 2 in p16 gene in gastric carcinoma. METHODS:The expression of p16 protein was examined by streptavidin-peroxidase conjuga...

journal_title：World journal of gastroenterology

authors： He XS,Su Q,Chen ZC,He XT,Long ZF,Ling H,Zhang LR

更新日期：2001-08-01 00:00:00

abstract：AIM:To examine the clinicopathologic features of elderly patients with gastric carcinoma and to investigate the relationship between prognosis and age. METHODS:We reviewed the hospital records of 2,014 patients with gastric carcinoma retrospectively to compare the clinicopathologic findings in elderly (age >70 years) ...

journal_title：World journal of gastroenterology

authors： Kim DY,Joo JK,Ryu SY,Park YK,Kim YJ,Kim SK

更新日期：2005-01-07 00:00:00

abstract：AIM:To analyze the relationship between perisinusoidal stellate cell (PSC) activation and the dietary fat quantity and composition in the treatment of hepatic steatosis. METHODS:Using an experimental rat model of steatosis based on the intake of a hyperlipidic diet (14% fat as olive oil or sunflower oil, HL-O and HL-S...

journal_title：World journal of gastroenterology

authors： Hernández R,Martínez-Lara E,Cañuelo A,del Moral ML,Blanco S,Siles E,Jiménez A,Pedrosa JA,Peinado MA

更新日期：2005-12-21 00:00:00

abstract：AIM:To investigate mucin expression profiles in colorectal carcinoma (CRC) histological subtypes with regard to clinicopathologic variables and prognosis. METHODS:Mucin (MUC)2 and MUC5AC expressions were assessed by immunohistochemistry for a total of 250 CRC cases that underwent surgical resection. CRCs included 63 w...

journal_title：World journal of gastroenterology

authors： Imai Y,Yamagishi H,Fukuda K,Ono Y,Inoue T,Ueda Y

更新日期：2013-07-07 00:00:00

abstract：:Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology characterized by hypergammaglobulinemia, autoantibodies detection and interface hepatitis. Due to the absence of specific diagnostic markers and the large heterogeneity of its clinical, laboratory and histological features, AIH ...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Zachou K,Koukoulis GK,Dalekos GN

更新日期：2015-01-07 00:00:00

abstract：:Transplantation is the optimal treatment for end-stage organ failure, and modern immunosuppression has allowed important progress in short-term outcomes. However, immunosuppression poorly influences chronic rejection and elicits chronic toxicity in current clinical practice. Thus, a major goal in transplantation is to...

journal_title：World journal of gastroenterology

authors： Baroja-Mazo A,Revilla-Nuin B,Parrilla P,Martínez-Alarcón L,Ramírez P,Pons JA

更新日期：2016-09-14 00:00:00

abstract：AIM:To investigate the frequency and timing of post-partum chronic hepatitis B virus (HBV) reactivation and identify its pre-partum predictors. METHODS:Forty-one hepatitis B e antigen (HBeAg)-negative chronic HBV infected pregnant women were prospectively evaluated between the 28th and the 32nd week of gestation. Subj...

journal_title：World journal of gastroenterology

authors： Elefsiniotis I,Vezali E,Vrachatis D,Hatzianastasiou S,Pappas S,Farmakidis G,Vrioni G,Tsakris A

更新日期：2015-01-28 00:00:00

abstract：AIM:To study the anti-hepatofibrosis mechanism of Bie Jia Jian oral liquid (BOL). METHODS:The model was induced by subcutaneous injection of CCl(4). BOL was administered and the change of serum hyaluronic acid (HA) and laminin (LN) was observed and the degeneration of liver cells and the degree of fibre hyperplasia an...

journal_title：World journal of gastroenterology

authors： Yao L,Yao ZM,Yu T

更新日期：2001-12-01 00:00:00

abstract：AIM:To evaluate the effect of dietary cholesterol and serum total cholesterol (TC) on the risk of pancreatic cancer. METHODS:A literature search was performed up to June 2014 in PubMed, EMBASE, China National Knowledge Infrastructure and China Biology Medical literature database for relevant articles published in Engl...

journal_title：World journal of gastroenterology

authors： Wang J,Wang WJ,Zhai L,Zhang DF

更新日期：2015-03-28 00:00:00

abstract：AIM:To evaluate the treatment of pediatric functional chronic intestinal constipation (FCIC) with a probiotic goat yogurt. METHODS:A crossover double-blind formula-controlled trial was carried out on 59 students (age range: 5-15 years) of a public school in Belo Horizonte, MG, Brazil, presenting a FCIC diagnostic, acc...

journal_title：World journal of gastroenterology

authors： Guerra PV,Lima LN,Souza TC,Mazochi V,Penna FJ,Silva AM,Nicoli JR,Guimarães EV

更新日期：2011-09-14 00:00:00

abstract：AIM:To investigate the seroprevalence and molecular characteristics of hepatitis E virus (HEV) in the illegal blood donors (IBDs) of central China in the early 1990s. METHODS:A total of 546 blood samples were collected from the IBDs in Maanshan city, a questionnaire was completed by each subject, detailing the age, se...

journal_title：World journal of gastroenterology

authors： Cheng XF,Wen YF,Zhu M,Zhan SW,Zheng JX,Dong C,Xiang KX,Xia XB,Wang G,Han LF

更新日期：2012-03-07 00:00:00

abstract：:Benign duodenal tumors are rare and less common than malignant tumors. Furthermore, vascular lesions of the duodenum, including hemangiomas, are rare causes of gastrointestinal bleeding. This report describes a case with bleeding hemangiomas in the third portion of the duodenum and jejunum and their successful treatme...

journal_title：World journal of gastroenterology

authors： Kanaji S,Nakamura T,Nishi M,Yamamoto M,Kanemitu K,Yamashiita K,Imanishi T,Sumi Y,Suzuki S,Tanaka K,Kakeji Y

更新日期：2014-09-14 00:00:00

abstract：AIM:To construct a DNA vaccine against extracellular domains 1-3 of fetal liver kinase-1 (flk-1), and to investigate its preventive and therapeutic effect against H22 cell in vivo. METHODS:Flk-1 DNA vaccine was produced by cloning extracellular domains 1-3 of flk-1 and by inserting the cloned gene into pcDNA3.1 (+). F...

journal_title：World journal of gastroenterology

authors： Lü F,Qin ZY,Yang WB,Qi YX,Li YM

更新日期：2004-07-15 00:00:00

abstract：:There was remarkable progress in the understanding of the role genetic risk factors in chronic pancreatitis. These factors seem to be much more important than thought in the past. The rare autosomal-dominant mutations N29I and R122H of PRSS1 (cationic trypsinogen) as well as the variant N34S of SPINK1 (pancreatic secr...

journal_title：World journal of gastroenterology

authors： Keim V

更新日期：2008-02-21 00:00:00

abstract：AIM:To investigate the optimum period of treatment for post endoscopic submucosal dissection (ESD) ulcers. METHODS:Patients who underwent ESD for gastric cancer were randomized to two groups and treated with esomeprazole 20 mg per day for 4 wk (4W group) or 2 wk (2W group). At 4 wk after ESD, we measured the size of t...

journal_title：World journal of gastroenterology

authors： Arai M,Matsumura T,Okimoto K,Oyamada A,Saito K,Minemura S,Maruoka D,Tanaka T,Nakagawa T,Katsuno T,Yokosuka O

更新日期：2014-11-21 00:00:00

abstract：BACKGROUND:Progressive familial intrahepatic cholestasis (PFIC) encompasses a group of autosomal recessive disorders with high morbidity and mortality. Variants in the gene encoding tight junction protein-2 (TJP2) have been linked to PFIC type 4 (PFIC4), which predominantly presents in childhood. However, there are onl...

journal_title：World journal of gastroenterology

authors： Wei CS,Becher N,Friis JB,Ott P,Vogel I,Grønbæk H

更新日期：2020-02-07 00:00:00