Role of genetic disorders in acute recurrent pancreatitis.

abstract：AIM:To detect significant clusters of co-expressed genes associated with tumorigenesis that might help to predict stomach adenocarcinoma (SA) prognosis. METHODS:The Cancer Genome Atlas database was used to obtain RNA sequences as well as complete clinical data of SA and adjacent normal tissues from patients. Weighted ...

journal_title：World journal of gastroenterology

authors： Zhang J,Wu Y,Jin HY,Guo S,Dong Z,Zheng ZC,Wang Y,Zhao Y

更新日期：2018-11-21 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：:Occult hepatitis B virus (HBV) infection (OBI), alternatively defined as occult hepatitis B (OHB), is a challenging clinical entity. It is recognized by two main characteristics: absence of HBsAg, and low viral replication. The previous two decades have witnessed a remarkable progress in our understanding of OBI and i...

journal_title：World journal of gastroenterology

authors： Said ZN

更新日期：2011-04-21 00:00:00

abstract：:The progressive loss of efficacy of standard eradication therapies has made the treatment of Helicobacter pylori (H. pylori) more challenging than ever. Endoscopic-guided antibiotic susceptibility testing had previously been suggested to guide treatment after failure of second-line therapies. However, its role has exp...

journal_title：World journal of gastroenterology

authors： Cammarota G,Ianiro G,Bibbò S,Di Rienzo TA,Masucci L,Sanguinetti M,Gasbarrini A

更新日期：2014-05-14 00:00:00

abstract：AIM:To investigate the relationship between pathological oropharyngeal (OP) acid exposure and esophageal motility in patients with extra-esophageal syndromes. METHODS:In this prospective study we enrolled consecutive outpatients with extra-esophageal symptoms suspected to be related to gastroesophageal reflux disease ...

journal_title：World journal of gastroenterology

authors： Passaretti S,Mazzoleni G,Vailati C,Testoni PA

更新日期：2016-10-28 00:00:00

abstract：:The small intestine is approximately 5-6 m long and occupies a large area in the abdominal cavity. These factors preclude the use of ordinary endoscopy and X-ray to thoroughly examine the small intestine for bleeding of vascular malformations. Thus, the diagnosis of intestinal bleeding is very difficult. A 47-year-old...

journal_title：World journal of gastroenterology

authors： Cui J,Huang LY,Lin SJ,Yi LZ,Wu CR,Zhang B

更新日期：2014-10-14 00:00:00

abstract：AIM:To detect the anomaly in the persistent right umbilical vein (PRUV) of portal vein (PV) with deviation of the ligamentum tere and left-sided gallbladder. METHODS:A total of 5783 candidates for routine analysis were evaluated for hepatic vascular abnormalities by ultrasonography. RESULTS:Ten candidates (0.17%) had...

journal_title：World journal of gastroenterology

authors： Nakanishi S,Shiraki K,Yamamoto K,Koyama M,Nakano T

更新日期：2005-02-28 00:00:00

abstract：:Benign neoplasia of the duodenum are very rare. Moreover, duodenal tubulovillous adenomas are more uncommon lesions. The microscopic structure of tubulovillous adenoma has frond-like projection of mucosa with branching papillary structure and generally upward growth into the lumen. We describe a 72-year-old man who sh...

journal_title：World journal of gastroenterology

authors： Kim JH,Choi JW,Seo YS,Lee BJ,Yeon JE,Kim JS,Byun KS,Bak YT,Kim I,Park JJ

更新日期：2007-06-21 00:00:00

abstract：AIM:To explore the grade and stage of pathology and the relationship between grading and staging of hepatic fibrosis and noninvasive diagnostic parameters. METHODS:Inflammatory activity and fibrosis of consecutive liver biopsies from 200 patients with chronic liver disease were determined according to the Diagnostic C...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Wan MB,Li CZ,Mao YM,Li JQ,Qiu DK,Cao AP,Ye J,Cai X,Chen CW,Wang JY,Wu SM,Zhu JS,Zhou XQ

更新日期：2003-11-01 00:00:00

abstract：:Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pa...

journal_title：World journal of gastroenterology

authors： Lin QJ,Yang F,Jin C,Fu DL

更新日期：2015-07-14 00:00:00

abstract：AIM:Over 90% of drugs are metabolized by the cytochrome P-450 (CYP) family of liver isoenzymes. The most important enzymes are CYP1A2, 3A4, 2C9/19, 2D6 and 2E1. Although CYP2D6 accounts for <2% of the total CYP liver enzyme content, it mediates metabolism in almost 25% of drugs. In order to study its enzymatic activity...

journal_title：World journal of gastroenterology

authors： Zhuge J,Yu YN,Wu XD

更新日期：2004-01-15 00:00:00

abstract：:Two-dimensional shear wave elastography (2D-SWE) is a rapid, simple and novel noninvasive method that has been proposed for assessing hepatic fibrosis in patients with chronic liver diseases (CLDs) based on measurements of liver stiffness. 2D-SWE can be performed easily at the bedside or in an outpatient clinic and yi...

journal_title：World journal of gastroenterology

authors： Xie LT,Yan CH,Zhao QY,He MN,Jiang TA

更新日期：2018-03-07 00:00:00

abstract：AIM:To evaluate the safety of lamivudine (LAM) treatment for chronic hepatitis B in early pregnancy. METHODS:A total of 92 pregnant women who received LAM treatment either before pregnancy or in early pregnancy were enrolled in this study. All of the pregnant women volunteered to take lamivudine during pregnancy and w...

journal_title：World journal of gastroenterology

authors： Yi W,Liu M,Cai HD

更新日期：2012-12-07 00:00:00

abstract：AIM:To investigate the effect of Jianweiyuyang (JWYY) granule on gastric ulcer recurrence and its mechanism in the treatment of gastric ulcer in rats. METHODS:Gastric ulcer in rats was induced according to Okeba's method with minor modification and the recurrence model was induced by IL-1beta. The expression of vascul...

journal_title：World journal of gastroenterology

authors： Dai XP,Li JB,Liu ZQ,Ding X,Huang CH,Zhou B

更新日期：2005-09-21 00:00:00

abstract：AIM:To describe the bowel habits and the prevalence of irritable bowel syndrome (IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS:This cross-sectional study was conducted at five major universities in Greater Beirut and its suburbs, between F...

journal_title：World journal of gastroenterology

authors： Costanian C,Tamim H,Assaad S

更新日期：2015-03-28 00:00:00

abstract：:Anorectal melanoma is a very rare tumor with poor prognosis. Rectal bleeding is the most frequent symptom and surgical treatment ranges from local excision to radical abdominoperineal resection. We report a case of a 75-years-old male patient who presented with a history of recurrent rectal bleeding, and whose histopa...

journal_title：World journal of gastroenterology

authors： Balicevic D,Tomic K,Bekavac-Beslin M,Kovacevic I,Mijic A,Belicza M,Kruslin B

更新日期：2006-06-07 00:00:00

abstract：:In this review, we discuss recent advances in nucleic acid-based therapeutic technologies that target hepatitis C virus (HCV) infection. Because the HCV genome is present exclusively in RNA form during replication, various nucleic acid-based therapeutic approaches targeting the HCV genome, such as ribozymes, aptamers,...

journal_title：World journal of gastroenterology

authors： Lee CH,Kim JH,Lee SW

更新日期：2013-12-21 00:00:00

abstract：AIM:To investigate the effect of Clostridium difficile (C. difficile) infection in an interleukin 10-deficient (IL-10(-/-)) mouse model of inflammatory bowel disease. METHODS:Bone marrow-derived dendritic cells isolated from wild type (WT) and IL-10(-/-)mice were stimulated for 4 h with C. difficile toxin A (200 μg/mL...

journal_title：World journal of gastroenterology

authors： Kim MN,Koh SJ,Kim JM,Im JP,Jung HC,Kim JS

更新日期：2014-12-07 00:00:00

abstract：:Ischemia/reperfusion (I/R) injury still represents an important cause of morbidity following hepatic surgery and limits the use of marginal livers in hepatic transplantation. Transient blood flow interruption followed by reperfusion protects tissues against damage induced by subsequent I/R. This process known as ische...

journal_title：World journal of gastroenterology

authors： Alchera E,Dal Ponte C,Imarisio C,Albano E,Carini R

更新日期：2010-12-28 00:00:00

abstract：:The Prague C and M Criteria have been developed for the objective endoscopic diagnosis of Barrett's esophagus (BE). BE arises between the squamocolumnar junction and the gastroesophageal junction at the proximal margin of the gastric folds. In this study, we reported that 43.0% of the subjects examined were diagnosed ...

journal_title：World journal of gastroenterology

authors： Akiyama T,Sekino Y,Iida H,Koyama S,Gotoh E,Maeda S,Nakajima A,Inamori M

更新日期：2012-07-14 00:00:00

abstract：:Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an...

journal_title：World journal of gastroenterology

authors： Haramura T,Haraguchi M,Irie J,Ito S,Tokai H,Noda K,Kitajima M,Minami S,Inoue K,Sasaki Y,Oshima K,Eguchi S

更新日期：2015-06-28 00:00:00

abstract：AIM:To investigate the expression and activity of leukotriene C4 (LTC4) synthesis enzymes and their underlying relationship with cysteinyl leukotriene (cys-LT) generation in a rat fulminant hepatic failure (FHF) model induced by D-galactosamine/lipopolysaccharide (D-GalN/ LPS). METHODS:Rats were treated with D-GalN (3...

journal_title：World journal of gastroenterology

authors： Ma KF,Yang HY,Chen Z,Qi LY,Zhu DY,Lou YJ

更新日期：2008-05-07 00:00:00

abstract：:Gastric intramural hematoma is a rare injury of the stomach, and is most often seen in patients with underlying disease. Such injury following endoscopic therapy is even rarer, and there are no universally accepted guidelines for its treatment. In this case report, we describe a gastric intramural hematoma which occur...

journal_title：World journal of gastroenterology

authors： Sun P,Tan SY,Liao GH

更新日期：2012-12-21 00:00:00

abstract：:AIM:To investigate the expression of somatostatin mRNA in various differentiated types of gastric carcinoma.METHODS: By using in situ hybridization and immunohistochemical techniques, the expression of somatostatin mRNA and somatostatin immunoreactivity in the normal gastric mucosa, the poorly, moderately and well-dif...

journal_title：World journal of gastroenterology

authors： Zhang QX,Dou YL,Shi XY,Ding Y

更新日期：1998-02-01 00:00:00

abstract：AIM:To explore the expression of macrophage inflammatory protein-1alpha (MIP-1alpha) in Kupffer cells (KCs) following liver ischemia/reperfusion injury IRI in rats. METHODS:Forty male SD rats were divided randomly into five groups. A model of partial warm ischemia/reperfusion injury in the rat liver was established. K...

journal_title：World journal of gastroenterology

authors： Ma W,Wang ZR,Shi L,Yuan Y

更新日期：2006-06-28 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer and has a 5-year survival of < 5%. Only about 15% of the patients present with a resectable PDAC with potential to undergo "curative" surgery. After surgery, local and systemic recurrence, is though very common. The median survival ...

journal_title：World journal of gastroenterology

authors： Ansari D,Gustafsson A,Andersson R

更新日期：2015-03-21 00:00:00

abstract：AIM:To investigate the existence and clinical significance of hepatitis C virus (HCV) RNA in the serum and peripheral blood mononuclear cells (PBMC) of patients with hepatitis C. METHODS:HCV RNA was detected by nested polymerase chain reaction (Nested PCR) in serum and in PBMC of 46 patients with acute hepatitis C (AH...

journal_title：World journal of gastroenterology

authors： Zhou P,Cai Q,Chen YC,Zhang MS,Guan J,Li XJ

更新日期：1997-06-15 00:00:00

abstract：:We report the case of a 57-year-old man who was diagnosed with a large unresectable cholangiocarcinoma associated with 2 satellite nodules and without clear margins with the right hepatic vein. Despite 4 cycles of GEMOX (stopped due to a hypertransaminasemia believed to be due to gemcitabine) and 4 cycles of FOLFIRINO...

journal_title：World journal of gastroenterology

authors： Servajean C,Gilabert M,Piana G,Monges G,Delpero JR,Brenot I,Raoul JL

更新日期：2014-05-07 00:00:00

abstract：AIM:To assess the efficiency and safety of radiofrequency-assisted hepatectomy in patients with hepatocellular carcinoma (HCC) and cirrhosis. METHODS:From January 2010 to December 2013, 179 patients with HCC and cirrhosis were recruited for this retrospective study. Of these, 100 patients who received radiofrequency-a...

journal_title：World journal of gastroenterology

authors： Zhang F,Yan J,Feng XB,Xia F,Li XW,Ma KS,Bie P

更新日期：2015-09-21 00:00:00

abstract：AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

journal_title：World journal of gastroenterology

authors： Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

更新日期：2004-10-01 00:00:00