An overview of occult hepatitis B virus infection.

Abstract:

:Occult hepatitis B virus (HBV) infection (OBI), alternatively defined as occult hepatitis B (OHB), is a challenging clinical entity. It is recognized by two main characteristics: absence of HBsAg, and low viral replication. The previous two decades have witnessed a remarkable progress in our understanding of OBI and its clinical implications. Appropriate diagnostic techniques must be adopted. Sensitive HBV DNA amplification assay is the gold standard assay for detection of OBI. Viral as well as host factors are implicated in the pathogenesis of OBI. However, published data reporting the infectivity of OBI by transfusion are limited. Several aspects including OBI transmission, infectivity and its relation to the development of chronic liver diseases and hepatocellular carcinoma have to be resolved. The aim of the present review is to highlight recent data on OBI with a focus on its virological diagnosis and clinical outcome.

journal_name

World J Gastroenterol

authors

Said ZN

doi

10.3748/wjg.v17.i15.1927

subject

Has Abstract

pub_date

2011-04-21 00:00:00

pages

1927-38

issue

15

eissn

1007-9327

issn

2219-2840

journal_volume

17

pub_type

社论,评审
  • Spices, herbal xenobiotics and the stomach: friends or foes?

    abstract::Spices and herbal remedies have been used since ancient times to treat a variety of disorders. It has been experimentally demonstrated that spices, herbs, and their extracts possess antimicrobial, anti-inflammatory, antirheumatic, lipid-lowering, hepatoprotective, nephroprotective, antimutagenic and anticancer activit...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v16.i22.2710

    authors: Al Mofleh IA

    更新日期:2010-06-14 00:00:00

  • Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization.

    abstract::Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis. Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolization, followed by left-sided hemihepatectomy. ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v12.i5.804

    authors: Leowardi C,Hormann Y,Hinz U,Wente MN,Hallscheidt P,Flechtenmacher C,Buchler MW,Friess H,Schwarzbach MH

    更新日期:2006-02-07 00:00:00

  • Distribution of trace metal concentrations in paired cancerous and non-cancerous human stomach tissues.

    abstract:AIM:To assess whether trace metal concentrations (which influence metabolism as both essential and non-essential elements) are increased or decreased in cancerous tissues and to understand the precise role of these metals in carcinogenesis. METHODS:Concentrations of trace metals including Cd, Ni, Cu, Zn, Fe, Mg and Ca...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i4.612

    authors: Yaman M,Kaya G,Yekeler H

    更新日期:2007-01-28 00:00:00

  • 1alpha, 25-dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital.

    abstract:AIM:To investigate the chemopreventive effects of 1alpha, 25-dihydroxyvitamin D(3) in diethylnitrosamine induced, phenobarbital promoted rat hepatocarcinogenesis. METHODS:The rats were randomly divided into 6 different groups (A-F). Groups A, C and E rats received a single intraperitoneal (i.p.) injection of diethylni...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i9.1268

    authors: Banakar MC,Paramasivan SK,Chattopadhyay MB,Datta S,Chakraborty P,Chatterjee M,Kannan K,Thygarajan E

    更新日期:2004-05-01 00:00:00

  • Use of chorioamniotic membrane instead of bogota bag in open abdomen: how i do it?

    abstract::It is one of the most important problems for general surgeons to decide which operation should be undertaken on patients with intra-abdominal infection, especially those with concomitant abdominal hypertension. Recently, closure techniques using prosthetic meshes in order to retain abdominal tension and to control sep...

    journal_title:World journal of gastroenterology

    pub_type: 信件

    doi:10.3748/wjg.14.815

    authors: Tekin S,Tekin A,Kucukkartallar T,Cakir M,Kartal A

    更新日期:2008-02-07 00:00:00

  • Growth hormone abolishes the negative effects of everolimus on intestinal wound healing.

    abstract:AIM:To investigate whether the simultaneous treatment with human growth hormone (hGH) abolishes the negative effects of everolimus on anastomotic healing. METHODS:Forty-eight male Sprague-Dawley-rats were randomized to three groups of 16 animals each (I: vehicle; II: everolimus 3 mg/kg po; III: everolimus 3 mg/kg po +...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i17.4321

    authors: Küper MA,Trütschel S,Weinreich J,Königsrainer A,Beckert S

    更新日期:2016-05-07 00:00:00

  • Relationship between RGS5 expression and differentiation and angiogenesis of gastric carcinoma.

    abstract:AIM:To explore the regulator of G-protein signaling 5 (RGS5) expression in gastric carcinoma and its association with differentiation and microvascular density (MVD). METHODS:Expression of RGS5 and CD34 were examined in 76 cases of gastric carcinoma, including 22 cases with lymph node metastasis and 54 cases without l...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i44.5642

    authors: Wang JH,Huang WS,Hu CR,Guan XX,Zhou HB,Chen LB

    更新日期:2010-11-28 00:00:00

  • Changes of gut flora and endotoxin in rats with D-galactosamine-induced acute liver failure.

    abstract:AIM:To investigate the changes of gut microflora and endotoxin levels in rats with acute liver failure (ALF) induced by D-galactosamine (GalN). METHODS:Flora and endotoxin levels in the jejunum, ileum and colon in normal rats (group A) and rats with GalN -induced ALF were determined at 24 h (group B) or 48 h (group C)...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i14.2087

    authors: Li LJ,Wu ZW,Xiao DS,Sheng JF

    更新日期:2004-07-15 00:00:00

  • Perforated appendiceal diverticulitis associated with appendiceal neurofibroma in neurofibromatosis type 1.

    abstract::An appendiceal neurofibroma (ANF) is a rare neoplasm associated with neurofibromatosis type 1(NF-1), an inheritable neurocutaneous disorder that involves multiple systems including the intraabdominal organs. Appendiceal diverticulitis occasionally ruptures in the absence of intense abdominal pain, which can lead to se...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i33.9817

    authors: Ozaki A,Tsukada M,Watanabe K,Tsubokura M,Kato S,Tanimoto T,Kami M,Ohira H,Kanazawa Y

    更新日期:2015-09-07 00:00:00

  • Pharmacological pain management in chronic pancreatitis.

    abstract::Intense abdominal pain is a prominent feature of chronic pancreatitis and its treatment remains a major clinical challenge. Basic studies of pancreatic nerves and experimental human pain research have provided evidence that pain processing is abnormal in these patients and in many cases resembles that seen in neuropat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i42.7292

    authors: Olesen SS,Juel J,Graversen C,Kolesnikov Y,Wilder-Smith OH,Drewes AM

    更新日期:2013-11-14 00:00:00

  • An effective and safe gastric endoscopic submucosal dissection in the right lateral position using an inverted overtube.

    abstract::Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i6.1623

    authors: Mori H,Rafiq K,Kobara H,Nishiyama N,Fujihara S,Yachida T,Ayagi M,Tani J,Miyoshi H,Masaki T

    更新日期:2014-02-14 00:00:00

  • Effect of interferon and ribavirin combined with amantadine in interferon and ribavirin non-responder patients with chronic hepatitis C (genotype 1).

    abstract:AIM:To evaluate the efficacy of amantadine plus interferon-alpha and ribavirin in non-responder patients with chronic hepatitis C. METHODS:Twenty-six non-responder patients received the regimen of IFN-alpha-2a at a dose of 6 million units three times a week, 1 000-1 200 mg of ribavirin daily, and 200 mg of amantadine ...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v11.i4.580

    authors: Oguz D,Cicek B,Filik L,Odemis B,Kilic M,Altintas E,Zengin N,Altiparmak E

    更新日期:2005-01-28 00:00:00

  • Efficacy of mycofenolate mofetil for steroid-resistant acute rejection after living donor liver transplantation.

    abstract:AIM:To discuss the use of mycophenolate mofetil (MMF) as an immunosuppressant in steroid resistant rejection after liver transplantation. METHODS:The clinical records of 260 adult patients who underwent living donor liver transplantation (LDLT) were reviewed. Tacrolimus and methylprednisolone were used for primary imm...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i30.4870

    authors: Akamatsu N,Sugawara Y,Tamura S,Matsui Y,Kaneko J,Makuuchi M

    更新日期:2006-08-14 00:00:00

  • Uric acid enhances T cell immune responses to hepatitis B surface antigen-pulsed-dendritic cells in mice.

    abstract:AIM:To study the induction of T cellular immune responses in BALB/c mice immunized with uric acid and dendritic cells (DCs) pulsed with hepatitis B virus surface antigen (HBsAg). METHODS:DCs were generated from bone-marrow cells of BABL/c mice, and then pulsed or unpulsed with HBsAg protein (HBsAg-pulsed-DCs or unpuls...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i7.1060

    authors: Ma XJ,Tian DY,Xu D,Yang DF,Zhu HF,Liang ZH,Zhang ZG

    更新日期:2007-02-21 00:00:00

  • Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease.

    abstract::The search for biomarkers that characterize specific aspects of inflammatory bowel disease (IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i44.12519

    authors: Quetglas EG,Mujagic Z,Wigge S,Keszthelyi D,Wachten S,Masclee A,Reinisch W

    更新日期:2015-11-28 00:00:00

  • Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis.

    abstract:AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i47.5351

    authors: Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

    更新日期:2018-12-21 00:00:00

  • Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava.

    abstract::Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). T...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.4204

    authors: Tomimaru Y,Nagano H,Marubashi S,Kobayashi S,Eguchi H,Takeda Y,Tanemura M,Kitagawa T,Umeshita K,Hashimoto N,Yoshikawa H,Wakasa K,Doki Y,Mori M

    更新日期:2009-09-07 00:00:00

  • Drug induced acute pancreatitis: does it exist?

    abstract::As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When con...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i44.16529

    authors: Tenner S

    更新日期:2014-11-28 00:00:00

  • Angiography for diagnosis and treatment of colorectal cancer.

    abstract:AIM:To evaluate the role of preoperative angiography in the diagnosis and treatment of colorectal cancer. METHODS:The authors performed selective arterial cannulation by Seldinger's method in 47 patients to locate the primary cancer and to diagnose metastasis to the liver. Each patient was then given intra-arterial re...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i2.288

    authors: Gu J,Ma ZL,Li Y,Li M,Xu GW

    更新日期:2003-02-01 00:00:00

  • Sealing of the hepatic resection area using fibrin glue reduces significant amount of postoperative drain fluid.

    abstract:AIM:To investigate whether the routine use of fibrin glue applied onto the hepatic resection area can diminish postoperative volume of bloody or biliary fluids drained via intraoperatively placed perihepatic tubes and can thus lower the complication rate. METHODS:Two groups of consecutive patients with a comparable sp...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v11.i38.5984

    authors: Eder F,Meyer F,Nestler G,Halloul Z,Lippert H

    更新日期:2005-10-14 00:00:00

  • Ceftriaxone-induced toxic hepatitis.

    abstract::Toxic hepatitis or drug-induced liver injury encompasses a spectrum of clinical disease ranging from mild biochemical abnormalities to acute liver failure. The advantages of a long half-life, wide spectrum, high tissue penetration rate, and a good safety profile, make ceftriaxone, a third-generation cephalosporin, a f...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.2669

    authors: Peker E,Cagan E,Dogan M

    更新日期:2009-06-07 00:00:00

  • Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats.

    abstract:AIM:To study the protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury and its mechanism after hemorrhagic shock in rats. METHODS:A total of 32 SD rats were randomly divided into four groups (n = 8, each group): normal group, model group, low dosage group (treated with 10 g/kg Astragalus...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i32.4986

    authors: Hei ZQ,Huang HQ,Zhang JJ,Chen BX,Li XY

    更新日期:2005-08-28 00:00:00

  • Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas.

    abstract:AIM:To determine the incidence of Epstein Barr virus associated gastric carcinoma (GC) in Brazil and compare the expressions of apoptosis related proteins and nitric oxide synthases between EBV positive and negative gastric carcinoma. METHODS:In situ hybridization of EBV-encoded small RNA-1 (EBER-1) and PCR was perfor...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i31.4959

    authors: Begnami MD,Montagnini AL,Vettore AL,Nonogaki S,Brait M,Simoes-Sato AY,Seixas AQ,Soares FA

    更新日期:2006-08-21 00:00:00

  • Comparison of protocatechuic aldchyde in Radix Salvia miltiorrhiza and corresponding pharmacological sera from normal and fibrotic rats by high performance liquid chromatography.

    abstract:AIM:To observe the effect of protocatechuic aldchyde on the proliferation of hepatic stellate cells (HSCs). METHODS:Liver fibrosis was induced in rats by carbon tetrachloride (CCl4). Then normal and fibrotic drug sera were extracted from rats. The effects of protocatechuic aldchyde, raw Radix Salvia miltiorrhiza and d...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i14.2195

    authors: Lv T,Yao XX

    更新日期:2006-04-14 00:00:00

  • Confocal laser endomicroscopy in inflammatory bowel diseases: dream or reality?

    abstract::Confocal laser endomicroscopy (CLE) is a newly introduced procedure that provide real-time, high-resolution imaging of the gastrointestinal mucosa during endoscopy, allowing the visualization of the pathology of the mucosal epithelium with its cellular and subcellular structures. Recently, the use of CLE was reported ...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v19.i34.5593

    authors: De Palma GD,Rispo A

    更新日期:2013-09-14 00:00:00

  • Comparative proteome analysis of untreated and Helicobacter pylori-treated HepG2.

    abstract:AIM:To investigate the pathological effect of Helicobacter pylori (H pylori) on human hepatic cells, proteomic methods were used to find and to identify proteins that were overexpressed in HepG2 cells treated by H pylori. METHODS:H pylori was co-cultured with HepG2 for 6 h. Two-dimensional gel electrophoresis was used...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i22.3485

    authors: Zhang Y,Fan XG,Chen R,Xiao ZQ,Feng XP,Tian XF,Chen ZH

    更新日期:2005-06-14 00:00:00

  • Chronic hepatitis B in children with or without malignancies: a 13-year follow-up.

    abstract:AIM:To evaluate the outcome of chronic hepatitis B (CHB) in children with or without malignancies. METHODS:Twenty four children (15 boys and 9 girls) with malignancies, followed up by the pediatric gastroenterology outpatient clinic for CHB between January 2000 and December 2013, were enrolled in the study (Group 1). ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i7.2073

    authors: Usta M,Urgancı N,Yıldırmak ZY,Dogan Vural S

    更新日期:2015-02-21 00:00:00

  • Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: a meta-analysis.

    abstract:AIM:To find evidences about whether NOD1/CARD4 insertion/deletion polymorphism is associated with inflammatory bowel disease by meta-analysis. METHODS:We surveyed the studies on the association of NOD1/CARD4 insertion/deletion polymorphism with inflammatory bowel disease in PubMed. Meta-analysis was performed for geno...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v16.i34.4348

    authors: Lu WG,Zou YF,Feng XL,Yuan FL,Gu YL,Li X,Li CW,Jin C,Li JP

    更新日期:2010-09-14 00:00:00

  • Posttransplant lymphoproliferative disorders following liver transplantation: Where are we now?

    abstract::Liver transplantation has emerged as a life-saving treatment for several patients with acute liver failure, end stage liver disease and primary hepatic malignancies. However, long term immunosuppressive therapy aiming to reduce the risk of transplant rejection increases the incidence of several complications including...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i39.11034

    authors: Dierickx D,Cardinaels N

    更新日期:2015-10-21 00:00:00

  • Effects of herbal compound 861 on human hepatic stellate cell proliferation and activation.

    abstract:AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i19.2831

    authors: Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

    更新日期:2004-10-01 00:00:00