Abstract:
:As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When confronted with a patient with acute pancreatitis and no clear etiology defined as an absence alcoholism, gallstones (ultrasound and/or MRI), a normal triglyceride level, and absence of tumor, it often appears reasonable to consider a drug as the cause of acute pancreatitis. Over 100 drugs have been implicated by case reports as causing acute pancreatitis. While some of these case reports are well written, many case reports represent poorly written experiences of the clinician simply implicating a drug without a careful evaluation. Over-reliance on case reports while ignoring randomized clinical trials and large pharmacoepidemiologic surveys has led to confusion about drug induced acute pancreatitis. This review will explain that drug induced acute pancreatitis does occur, but it is rare, and over diagnosis leads to misconceptions about the disease resulting in inappropriate patient care, increased litigation and a failure to address the true entity: idiopathic acute pancreatitis.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Tenner Sdoi
10.3748/wjg.v20.i44.16529subject
Has Abstractpub_date
2014-11-28 00:00:00pages
16529-34issue
44eissn
1007-9327issn
2219-2840journal_volume
20pub_type
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2016-08-21 00:00:00
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