Ephrin-B reverse signaling induces expression of wound healing associated genes in IEC-6 intestinal epithelial cells.

abstract：AIM:To evaluate the prognosis of type II diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS:403 gastric cancer patients with T2DM were studied, who underwent gastrectomy between May 2003 and September 2009. A review of medical records and telephone interviews was perform...

journal_title：World journal of gastroenterology

authors： Kim JW,Cheong JH,Hyung WJ,Choi SH,Noh SH

更新日期：2012-01-07 00:00:00

abstract：AIM:To investigate markers for high-grade dysplasia for the optimal timing of liver transplantation in patients with primary sclerosing cholangitis (PSC). METHODS:Earlier data support a dysplasia-carcinoma sequence, even low- to high-grade dysplasia, in PSC-associated cholangiocarcinoma (CCA). Surveillance using endos...

journal_title：World journal of gastroenterology

authors： Boyd S,Vannas M,Jokelainen K,Isoniemi H,Mäkisalo H,Färkkilä MA,Arola J

更新日期：2017-09-07 00:00:00

abstract：:Pancreatic cancer is a leading cause of cancer mortality and the incidence of this disease is expected to continue increasing. While patients with pancreatic cancer have traditionally faced a dismal prognosis, over the past several years various advances in diagnosis and treatment have begun to positively impact this ...

journal_title：World journal of gastroenterology

authors： Mohammed S,Van Buren G 2nd,Fisher WE

更新日期：2014-07-28 00:00:00

abstract：AIM:To immunohistochemically examine micrometastasis and VEGF-C expression in hilar bile duct carcinoma (HBDC) and to evaluate the clinical significance of the results. METHODS:A total of 361 regional lymph nodes from 25 patients with node-negative HBDC were immunostained with an antibody against cytokeratins 8 and 18...

journal_title：World journal of gastroenterology

authors： Taniguchi K,Iida T,Hori T,Yagi S,Imai H,Shiraishi T,Uemoto S

更新日期：2006-04-28 00:00:00

abstract：AIM:To investigate the relationship between c.343A>G and c.2216A>C polymorphism sites in the CDH17 gene and colorectal carcinoma. METHODS:Ninety-three non-consanguineous colorectal carcinoma patients admitted to the Department of Oncology at the First Affiliated Hospital of Zhengzhou University were included in this s...

journal_title：World journal of gastroenterology

authors： Chen RY,Cao JJ,Chen J,Yang JP,Liu XB,Zhao GQ,Zhang YF

更新日期：2012-12-28 00:00:00

abstract：:The diagnosis of herbal hepatotoxicity or herb induced liver injury (HILI) represents a particular clinical and regulatory challenge with major pitfalls for the causality evaluation. At the day HILI is suspected in a patient, physicians should start assessing the quality of the used herbal product, optimizing the clin...

journal_title：World journal of gastroenterology

authors： Teschke R,Frenzel C,Schulze J,Eickhoff A

更新日期：2013-05-21 00:00:00

abstract：AIM:Oxygen free radical mediated tissue damage is well established in pathogenesis of acute pancreatitis (AP). Whether nitric oxide (NO) plays a deleterious or a protective role is unknown. In alcohol-induced AP, we studied NO, lipooxidative damage and glutathione in pancreas, lung and circulation. METHODS:AP was indu...

journal_title：World journal of gastroenterology

authors： Andican G,Gelisgen R,Unal E,Tortum OB,Dervisoglu S,Karahasanoglu T,Burçak G

更新日期：2005-04-21 00:00:00

abstract：:The goal of therapy in chronic hepatitis C virus (HCV) infection is sustained virological response (SVR) which reflects HCV eradication. Treatment against HCV has dramatically improved with the recent availability of direct-acting antivirals (DAAs) including sofosbuvir, simeprevir, daclatasvir, ledipasvir/sofosbuvir, ...

journal_title：World journal of gastroenterology

authors： Cholongitas E,Pipili C,Papatheodoridis G

更新日期：2015-08-28 00:00:00

abstract：AIM:To retrospectively analyze factors affecting the long-term survival of patients with pancreatic cancer who underwent pancreatic resection. METHODS:From January 2000 to December 2011, 195 patients underwent pancreatic resection in our hospital. The prognostic factors after pancreatic resection were analyzed in all ...

journal_title：World journal of gastroenterology

authors： Yamamoto T,Yagi S,Kinoshita H,Sakamoto Y,Okada K,Uryuhara K,Morimoto T,Kaihara S,Hosotani R

更新日期：2015-01-07 00:00:00

abstract：BACKGROUND:The digestive tract is the maximal immunizing tissue in the body, and mucosal integrity and functional status of the gut is very important to maintain a healthy organism. Severe infection is one of the most common causes of gastrointestinal dysfunction, and the pathogenesis is closely related to endotoxemia ...

journal_title：World journal of gastroenterology

authors： Wang W,Sun M,Zheng YL,Sun LY,Qu SQ

更新日期：2019-06-21 00:00:00

abstract：AIM:To investigate the expression of hypoxia-inducible factor (HIF)-2alpha/endothelial PAS domain protein1 (EPAS1) in hepatocellular carcinoma (HCC). METHODS:Expression of HIF-2alpha/EPAS1 was investigated immunohistochemically on paraffin-embedded sections from 97 patients with HCC. To further confirm that HIF-2alpha...

journal_title：World journal of gastroenterology

authors： Bangoura G,Yang LY,Huang GW,Wang W

更新日期：2004-02-15 00:00:00

abstract：:An appendiceal neurofibroma (ANF) is a rare neoplasm associated with neurofibromatosis type 1(NF-1), an inheritable neurocutaneous disorder that involves multiple systems including the intraabdominal organs. Appendiceal diverticulitis occasionally ruptures in the absence of intense abdominal pain, which can lead to se...

journal_title：World journal of gastroenterology

authors： Ozaki A,Tsukada M,Watanabe K,Tsubokura M,Kato S,Tanimoto T,Kami M,Ohira H,Kanazawa Y

更新日期：2015-09-07 00:00:00

abstract：AIM:To examine the possible effects of honey supplementation on hepatic damage due to obstruction of the common bile duct in an experimental rat model. METHODS:The study was performed with 30 male rats divided into three groups: a sham group, an obstructive jaundice group, and an obstructive jaundice plus honey group....

journal_title：World journal of gastroenterology

authors： Erguder BI,Kilicoglu SS,Namuslu M,Kilicoglu B,Devrim E,Kismet K,Durak I

更新日期：2008-06-21 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography (ERCP) is a state of the art diagnostic and therapeutic procedure for various pancreatic and biliary problems. In spite of the well-established safety of the procedure, there is still a risk of complications such as pancreatitis, cholangitis, bleeding and perforation. Air...

journal_title：World journal of gastroenterology

authors： Yilmaz B,Roach EC,Koklu S,Aydin O,Unlu O,Kilic YA

更新日期：2015-04-21 00:00:00

abstract：:Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the pathogenesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present sys...

journal_title：World journal of gastroenterology

authors： Salari P,Abdollahi M

更新日期：2011-10-14 00:00:00

abstract：AIM:To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device. METHODS:Seventy consecutive patients with 96 early esophageal neoplasms, who underwent ESD using a SB knife at Kure Medical Center and Chugoku Cancer Center, Japan, betwee...

journal_title：World journal of gastroenterology

authors： Kuwai T,Yamaguchi T,Imagawa H,Miura R,Sumida Y,Takasago T,Miyasako Y,Nishimura T,Iio S,Yamaguchi A,Kouno H,Kohno H,Ishaq S

更新日期：2018-04-21 00:00:00

abstract：:Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of virally infected cells in the liver is related to the HCV-induced inability of the immune system to reco...

journal_title：World journal of gastroenterology

authors： Osna NA

更新日期：2009-03-14 00:00:00

abstract：AIM:To investigate the reasons for the occurrence of the pink-color sign of iodine-unstained lesions. METHODS:In chromoendoscopy, the pink-color sign of iodine-unstained lesions is recognized as useful for the diagnosis of esophageal squamous cell carcinoma. Patients with superficial esophageal neoplasms treated by en...

journal_title：World journal of gastroenterology

authors： Ishihara R,Kanzaki H,Iishi H,Nagai K,Matsui F,Yamashina T,Matsuura N,Ito T,Fujii M,Yamamoto S,Hanaoka N,Takeuchi Y,Higashino K,Uedo N,Tatsuta M,Tomita Y,Ishiguro S

更新日期：2013-07-21 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：AIM:To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS:Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM....

journal_title：World journal of gastroenterology

authors： Sung CM,Hsu CM,Hsu JT,Yeh TS,Lin CJ,Chen TC,Su MY,Chiu CT

更新日期：2010-11-07 00:00:00

abstract：AIM:To investigate the genetic relationship between Hirschsprung's disease (HD) and intestinal neuronal dysplasia (IND) in Chinese population. METHODS:Peripheral blood samples were obtained from 30 HD patients, 20 IND patients, 18 HD/IND combined patients and 20 normal individuals as control. Genomic DNA was extracted...

journal_title：World journal of gastroenterology

authors： Tou JF,Li MJ,Guan T,Li JC,Zhu XK,Feng ZG

更新日期：2006-02-21 00:00:00

abstract：AIM:To investigate the seroprevalence and molecular characteristics of hepatitis E virus (HEV) in the illegal blood donors (IBDs) of central China in the early 1990s. METHODS:A total of 546 blood samples were collected from the IBDs in Maanshan city, a questionnaire was completed by each subject, detailing the age, se...

journal_title：World journal of gastroenterology

authors： Cheng XF,Wen YF,Zhu M,Zhan SW,Zheng JX,Dong C,Xiang KX,Xia XB,Wang G,Han LF

更新日期：2012-03-07 00:00:00

abstract：:Corticosteroids and immunomodulators have been the mainstay therapies for Crohn's disease. Corticosteroids are highly effective to control symptoms in the short-term, but they are not effective in maintaining remission, they heal the mucosa in a reduced proportion of cases, and long-time exposure is associated with an...

journal_title：World journal of gastroenterology

authors： Ricart E,García-Bosch O,Ordás I,Panés J

更新日期：2008-09-28 00:00:00

abstract：AIM:To investigate the predictive clinical value of in vitro 3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide (MTT) assay for directing chemosensitivity in patients with gastric cancer. METHODS:Results of a total of 353 consecutive patients with gastric cancer treated with MTT-directed chemotherapy or phys...

journal_title：World journal of gastroenterology

authors： Wu B,Zhu JS,Zhang Y,Shen WM,Zhang Q

更新日期：2008-05-21 00:00:00

abstract：AIM:To evaluate the potential use of colonoscopy and endoluminal ultrasonic biomicroscopy (eUBM) to track the progression of mouse colonic lesions. METHODS:Ten mice were treated with a single azoxymethane intraperitoneal injection (week 1) followed by seven days of a dextran sulfate sodium treatment in their drinking ...

journal_title：World journal of gastroenterology

authors： Soletti RC,Alves KZ,de Britto MA,de Matos DG,Soldan M,Borges HL,Machado JC

更新日期：2013-11-28 00:00:00

abstract：AIM:To investigate the molecular mechanism and functional consequences of heme oxygenase-1 (HO-1) activation by lansoprazole in endothelial cells and macrophages. METHODS:Expression of HO-1 mRNA was analyzed by Northern blotting. Western blotting was used to determine the HO-1 and ferritin protein levels. NADPH-depend...

journal_title：World journal of gastroenterology

authors： Schulz-Geske S,Erdmann K,Wong RJ,Stevenson DK,Schröder H,Grosser N

更新日期：2009-09-21 00:00:00

abstract：BACKGROUND:Sequential transarterial chemoembolization (TACE) and portal vein embolization (PVE) are associated with long time interval that can allow tumor growth and nullify treatments' benefits. AIM:To evaluate the effect of simultaneous TACE and PVE for patients with large hepatocellular carcinoma (HCC) prior to el...

journal_title：World journal of gastroenterology

authors： Zhang CW,Dou CW,Zhang XL,Liu XQ,Huang DS,Hu ZM,Liu J

更新日期：2020-08-14 00:00:00

abstract：AIM:To evaluate the utility of local tumor therapy combined with percutaneous transhepatic biliary drainage (PTBD) for malignant obstructive biliary disease. METHODS:A total of 233 patients with malignant biliary obstruction were treated in our hospital with PTBD by placement of metallic stents and/or plastic tubes. A...

journal_title：World journal of gastroenterology

authors： Qian XJ,Zhai RY,Dai DK,Yu P,Gao L

更新日期：2006-01-14 00:00:00

abstract：:Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic metho...

journal_title：World journal of gastroenterology

authors： Garza-González E,Perez-Perez GI,Maldonado-Garza HJ,Bosques-Padilla FJ

更新日期：2014-02-14 00:00:00

abstract：AIM:To evaluate clinical presentation, etiology, complications and response to treatment in elderly patients with acute cholangitis. METHODS:Demographics, etiology of biliary obstruction, clinical features, complications and associated systemic diseases of 175 patients with acute cholangitis were recorded. Endoscopic ...

journal_title：World journal of gastroenterology

authors： Agarwal N,Sharma BC,Sarin SK

更新日期：2006-10-28 00:00:00