Molecular mechanism and functional consequences of lansoprazole-mediated heme oxygenase-1 induction.

abstract：AIM:To identify a molecular marker for gastric cancer, and to investigate the relationship between the polymorphism of pepsinogen C (PGC) gene and the genetic predisposition to gastric cancer. METHODS:A total of 289 cases were involved in this study. 115 cases came from Shenyang area, a low risk area of gastric cancer...

journal_title：World journal of gastroenterology

authors： Liu HJ,Guo XL,Dong M,Wang L,Yuan Y

更新日期：2003-01-01 00:00:00

abstract：AIM:To evaluate the impact of time interval for hemofiltration (HF) on the prognosis of severe acute pancreatitis (SAP). METHODS:Thirty-six consecutive patients with severe acute pancreatitis were included in the study. Atlanta classification system was applied for stratification. They were randomly divided into short...

journal_title：World journal of gastroenterology

authors： Mao EQ,Tang YQ,Zhang SD

更新日期：2003-02-01 00:00:00

abstract：AIM:To investigate the post-colonoscopy colorectal cancer (PCCRC) rate for high-definition (HD) colonoscopy compared with that for standard-definition colonoscopy reported previously. METHODS:Using medical records at Sano Hospital (SH) and Dokkyo Medical University Koshigaya Hospital (DMUKH), we retrospectively obtain...

journal_title：World journal of gastroenterology

authors： Iwatate M,Kitagawa T,Katayama Y,Tokutomi N,Ban S,Hattori S,Hasuike N,Sano W,Sano Y,Tamano M

更新日期：2017-11-14 00:00:00

abstract：AIM:To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA). METHODS:WB-F344 cells were continuously exposed to 7 x 10(-7) mol/L H2O2 for 21 d. Observations of cell morphology, colony formation rates, flow cyt...

journal_title：World journal of gastroenterology

authors： Han YY,Xue XW,Shi ZM,Wang PY,Wu XR,Wang XJ

更新日期：2014-02-07 00:00:00

abstract：:Colorectal adenocarcinoma (CRC) is the third most common type of cancer and the fourth most frequent cause of death due to cancer worldwide. Given the natural history of CRC, early diagnosis appears to be the most appropriate tool to reduce disease-related mortality. A field of recent interest is clinical proteomics, ...

journal_title：World journal of gastroenterology

authors： de Noo ME,Tollenaar RA,Deelder AM,Bouwman LH

更新日期：2006-11-07 00:00:00

abstract：AIM:To counteract/reveal celecoxib-induced toxicity and NO system involvement. METHODS:Celecoxib (1 g/kg b.w. ip) was combined with therapy with stable gastric pentadecapeptide BPC 157 (known to inhibit these lesions, 10 μg/kg, 10 ng/kg, or 1 ng/kg ip) and L-arginine (100 mg/kg ip), as well as NOS blockade [N(G)-nitro...

journal_title：World journal of gastroenterology

authors： Drmic D,Kolenc D,Ilic S,Bauk L,Sever M,Zenko Sever A,Luetic K,Suran J,Seiwerth S,Sikiric P

更新日期：2017-08-07 00:00:00

abstract：:Neuroendocrine carcinoma (NEC) of the gallbladder is a rare subtype of gallbladder tumor. Here, we report two cases of NEC in two patients initially suspected to have gallbladder carcinoma. No specific symptoms or abnormal blood test results were observed preoperatively. Abdominal computed tomography scans indicated i...

journal_title：World journal of gastroenterology

authors： Chen H,Shen YY,Ni XZ

更新日期：2014-09-07 00:00:00

abstract：:In their seminal papers Hanahan and Weinberg described oncogenic processes a normal cell undergoes to be transformed into a cancer cell. The functions of ion channels in the gastrointestinal (GI) tract influence a variety of cellular processes, many of which overlap with these hallmarks of cancer. In this review we fo...

journal_title：World journal of gastroenterology

authors： Anderson KJ,Cormier RT,Scott PM

更新日期：2019-10-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver. It is the second leading cause of cancer-related deaths worldwide, with a very poor prognosis. In the United States, there has been only minimal improvement in the prognosis for HCC patients over the past 15 years. Details of the molecu...

journal_title：World journal of gastroenterology

authors： Ogunwobi OO,Harricharran T,Huaman J,Galuza A,Odumuwagun O,Tan Y,Ma GX,Nguyen MT

更新日期：2019-05-21 00:00:00

abstract：:Strong evidence supports the concept of immunosurveillance and immunoediting in colorectal cancer. In particular, the density of T CD8⁺ and CD45⁺ lymphocyte infiltration was recently shown to have a better prognostic value than the classic tumor node metastasis classification factor. Other immune subsets, as macrophag...

journal_title：World journal of gastroenterology

authors： Pernot S,Terme M,Voron T,Colussi O,Marcheteau E,Tartour E,Taieb J

更新日期：2014-04-14 00:00:00

abstract：:The clinical course of chronic liver diseases is significantly dependent on the progression rate and the extent of fibrosis, i.e. the non-structured replacement of necrotic parenchyma by extracellular matrix. Fibrogenesis, i.e. the development of fibrosis can be regarded as an unlimited wound healing process, which is...

journal_title：World journal of gastroenterology

authors： Gressner AM,Gao CF,Gressner OA

更新日期：2009-05-28 00:00:00

abstract：:Over the past decade, research has shown that aberrant expression of microRNA (miRNA) is involved in colorectal cancer development and progression. MicroRNAs are small sequences of non-coding RNA that regulate expression of genes involved in important cellular functions, such as cell differentiation, multiplication, a...

journal_title：World journal of gastroenterology

authors： Hollis M,Nair K,Vyas A,Chaturvedi LS,Gambhir S,Vyas D

更新日期：2015-07-21 00:00:00

abstract：:Hepatitis C virus (HCV) infection after biological accident (needlestick injury) is a rare event. This report describes the first case of acute HCV infection after a needlestick injury in a female nursing student at Padua University Hospital. The student nurse was injured on the second finger of the right hand when re...

journal_title：World journal of gastroenterology

authors： Scaggiante R,Chemello L,Rinaldi R,Bartolucci GB,Trevisan A

更新日期：2013-01-28 00:00:00

abstract：AIM:To study the predictive value of the vegetative-depressive symptoms of the Zung Depression Rating Scale for the occurrence of depression during treatment with peg-interferon alpha-2b of chronic hepatitis C (CHC) patients. METHODS:The predictive value of vegetative-depressive symptoms at 4 wk of treatment for the o...

journal_title：World journal of gastroenterology

authors： Robaeys G,De Bie J,Wichers MC,Bruckers L,Nevens F,Michielsen P,Van Ranst M,Buntinx F

更新日期：2007-11-21 00:00:00

abstract：:Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis in the presence of the intestinal diverticula, surgical enteroanastomoses, blind pouches, afferent loops, incarcerated hernias, small intestinal tumors, intestinal kinking fro...

journal_title：World journal of gastroenterology

authors： Gurvits GE,Lan G

更新日期：2014-12-21 00:00:00

abstract：AIM:To prospectively evaluate the effectiveness and safety of continuous wound infiltration (CWI) for pain management after open gastrectomy. METHODS:Seventy-five adult patients with American Society of Anesthesiologists (ASA) Physical Status Classification System (ASA) grade 1-3 undergoing open gastrectomy were rando...

journal_title：World journal of gastroenterology

authors： Zheng X,Feng X,Cai XJ

更新日期：2016-02-07 00:00:00

abstract：:Irritable bowel syndrome (IBS) is an extremely prevalent but poorly understood gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help diagnose the disorder and treatment options are limited to management of the symptoms. The concept of a dysregulated gut-brain axis has been adopted as a...

journal_title：World journal of gastroenterology

authors： Kennedy PJ,Cryan JF,Dinan TG,Clarke G

更新日期：2014-10-21 00:00:00

abstract：:We describe herein a 68-year-old woman who was diagnosed with a quite rare entity of intraductal papillary mucinous neoplasms (IPMNs) occurring simultaneously in the left lateral lobe of liver and the tail of pancreas. Abdominal computed tomography and magnetic resonance cholangiopancreatography showed a cystic dilata...

journal_title：World journal of gastroenterology

authors： Xu XW,Li RH,Zhou W,Wang J,Zhang RC,Chen K,Mou YP

更新日期：2012-11-28 00:00:00

abstract：AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

journal_title：World journal of gastroenterology

authors： Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

更新日期：2006-01-14 00:00:00

abstract：AIM:To investigate the relationship and molecular features of CD74/macrophage migration inhibitory factor (MIF)/Toll-like receptor 4 (TLR4) in gastric cancer. METHODS:CD74, MIF and TLR4 expression in the paraffin-embedded sections of gastric cancer from 120 patients were detected by immunohistochemical staining. Knock...

journal_title：World journal of gastroenterology

authors： Zheng YX,Yang M,Rong TT,Yuan XL,Ma YH,Wang ZH,Shen LS,Cui L

更新日期：2012-05-14 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is a group of diseases with excess fat in liver in the absence of a poorly defined limit of alcohol consumption. Most common variety, a universal public health problem, is associated with insulin resistance caused by a host of genetic and epigenetic defects modulated by life st...

journal_title：World journal of gastroenterology

authors： Sanal MG

更新日期：2008-02-14 00:00:00

abstract：:Hilar tumors have proven to be a challenge to treat and manage because of their poor sensitivity to conventional therapies and our inability to prevent or to detect early tumor formation. Endoscopic stent drainage has been proposed as an alternative to biliary-enteric bypass surgery and percutaneous drainage to pallia...

journal_title：World journal of gastroenterology

authors： De Palma GD,Masone S,Rega M,Simeoli I,Salvatori F,Siciliano S,Maione F,Girardi V,Celiento M,Persico G

更新日期：2007-08-14 00:00:00

abstract：:Acute pancreatitis is an inflammatory disorder of the pancreas that may cause life-threatening complications. Etiologies of pancreatitis vary, with gallstones accounting for the majority of all cases, followed by alcohol. Other causes of pancreatitis include trauma, ischemia, mechanical obstruction, infections, autoim...

journal_title：World journal of gastroenterology

authors： Binker MG,Cosen-Binker LI

更新日期：2014-05-21 00:00:00

abstract：:Although a number of cases of hepatotoxicity are associated with the use of Hydroxycut weight management products, it has been alleged that their effects are primarily due to the presence of hydroxycitric acid (HCA, as Super CitriMax) in the formulations. However, while these products contain up to 20 different ingred...

journal_title：World journal of gastroenterology

authors： Stohs SJ,Preuss HG,Ohia SE,Kaats GR,Keen CL,Williams LD,Burdock GA

更新日期：2009-08-28 00:00:00

abstract：AIM:To explore the relationship between α-fetoprotein (AFP) and various clinicopathological variables and different staging system of hepatocellular carcinoma (HCC) thoroughly. METHODS:A retrospective cohort study of consecutive patients diagnosed with HCC between January 2008 and December 2009 in West China Hospital ...

journal_title：World journal of gastroenterology

authors： Liu C,Xiao GQ,Yan LN,Li B,Jiang L,Wen TF,Wang WT,Xu MQ,Yang JY

更新日期：2013-03-21 00:00:00

abstract：AIM:To study the relationship between the patterns of postprandial peristalsis and transduodenal bolus transport in healthy subjects. METHODS:Synchronous recording of chyme transport and peristaltic activity was performed during the fasting state and after administration of a test meal using a special catheter device ...

journal_title：World journal of gastroenterology

authors： Nguyen HN,Winograd R,Domingues GR,Lammert F

更新日期：2006-10-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most lethal cancers, and its rate of incidence is rising annually. Despite the progress in diagnosis and treatment, the overall prognoses of HCC patients remain dismal due to the difficulties in early diagnosis and the high level of tumor invasion, metastasis and recurrence...

journal_title：World journal of gastroenterology

authors： Shang RZ,Qu SB,Wang DS

更新日期：2016-12-07 00:00:00

abstract：:Recently, the use of confocal laser endomicroscopy (CLE) in the diagnosis of chronic ulcerative colitis (CUC) was reported. In this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in CUC. The study involved a patient presenting long-standing CUC. Confocal...

journal_title：World journal of gastroenterology

authors： De Palma GD,Staibano S,Siciliano S,Maione F,Siano M,Esposito D,Persico G

更新日期：2011-02-07 00:00:00

abstract：AIM:To assess the patient-reported outcomes (PROs) of pancreatic neuroendocrine tumor (PNET) patients. METHODS:Fifty-one consecutive patients (21 male, 30 female, 61.0 +/- 10.3 years) with proven PNETs were studied. An SF-12 questionnaire capable of exploring the physical (PCS) and mental (MCS) aspects of daily life w...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Campana D,Morselli-Labate AM,Fabbri MC,Brocchi E,Tomassetti P

更新日期：2009-10-28 00:00:00

abstract：:Anti-tumour necrosis factor α (anti-TNFα) therapy is an established treatment in inflammatory bowel disease. However, this treatment is associated with high costs and the possibility of severe adverse events representing a true challenge for patients, clinicians and health care systems. Consequently, a crucial questio...

journal_title：World journal of gastroenterology

authors： Papamichael K,Vermeire S

更新日期：2015-04-28 00:00:00