Mechanisms of hepatocellular carcinoma progression.

abstract：AIM:To assess intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) for monitoring early efficacy of chemotherapy in a human gastric cancer mouse model. METHODS:IVIM-DWI was performed with 12 b-values (0-800 s/mm(2)) in 25 human gastric cancer-bearing nude mice at baseline (day 0), and then they were rand...

journal_title：World journal of gastroenterology

authors： Song XL,Kang HK,Jeong GW,Ahn KY,Jeong YY,Kang YJ,Cho HJ,Moon CM

更新日期：2016-06-28 00:00:00

abstract：AIM:To evaluate the utility of measuring epigenetic alterations in pancreatic and biliary fluids in determining molecular markers for pancreatobiliary cancers. METHODS:DNA was extracted from undiluted pancreatic and biliary fluids. As a surrogate for a genome-wide hypomethylation assay, levels of long interspersed nuc...

journal_title：World journal of gastroenterology

authors： Kato N,Yamamoto H,Adachi Y,Ohashi H,Taniguchi H,Suzuki H,Nakazawa M,Kaneto H,Sasaki S,Imai K,Shinomura Y

更新日期：2013-03-21 00:00:00

abstract：AIM:To examine the possible effects of honey supplementation on hepatic damage due to obstruction of the common bile duct in an experimental rat model. METHODS:The study was performed with 30 male rats divided into three groups: a sham group, an obstructive jaundice group, and an obstructive jaundice plus honey group....

journal_title：World journal of gastroenterology

authors： Erguder BI,Kilicoglu SS,Namuslu M,Kilicoglu B,Devrim E,Kismet K,Durak I

更新日期：2008-06-21 00:00:00

abstract：:Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. The identification of colonic polyps can reduce CRC mortality through earlier diagnosis of cancers and the removal of polyps: the precursor lesion of CRC. Following the finding and removal of colonic polyps at an initial colonoscopy, some p...

journal_title：World journal of gastroenterology

authors： Bonnington SN,Rutter MD

更新日期：2016-02-14 00:00:00

abstract：AIM:To examine the role of microRNA 1181 (miR-1181) in invasion and proliferation in pancreatic cancer. METHODS:We analyzed the expression of miR-1181 in several pancreatic cancer cell lines and generated stable MIA-PaCa-2 and PANC-1 cell lines with up-regulated miR-1181 expression using an adenovirus delivery system....

journal_title：World journal of gastroenterology

authors： Wang J,Guo XJ,Ding YM,Jiang JX

更新日期：2017-03-07 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a disease of the biliary tract, which has been documented in the literature since 1867. This disease has a strong predilection for affecting men and can be seen in individuals as young as 2 years of age. PSC has a strong associated with inflammatory bowel disease, more commonly ...

journal_title：World journal of gastroenterology

authors： Gidwaney NG,Pawa S,Das KM

更新日期：2017-04-14 00:00:00

abstract：AIM:To determine the immune-modulatory and the hepatoprotective effects of oral administration of two soy extracts in immune mediated liver injury and non-alcoholic steatohepatitis (NASH). METHODS:Two soy extracts, M1 and OS, were orally administered to mice with concanavalin A (ConA) immune-mediated hepatitis, to hig...

journal_title：World journal of gastroenterology

authors： Khoury T,Ben Ya'acov A,Shabat Y,Zolotarovya L,Snir R,Ilan Y

更新日期：2015-06-28 00:00:00

abstract：:Xanthogranulomatous inflammation (XGI) is a disease of unknown origin, most frequently described in the kidney and gallbladder; its localization in the colorectal tract is extremely rare. The extension of the typical inflammatory process to the surrounding tissues may lead to misdiagnosis as cancer. We report the case...

journal_title：World journal of gastroenterology

authors： Addario Chieco P,Antolino L,Giaccaglia V,Centanini F,Cunsolo GV,Sparagna A,Uccini S,Ziparo V

更新日期：2014-07-14 00:00:00

abstract：AIM:To investigate the expression and clinical significance of B7 homolog 3 (B7-H3) and β-1,3-galactosyltransferase-4 (B3GALT4) in colorectal cancer (CRC) patients. METHODS:Using tissue microarray, we identified the expression of B7-H3 and B3GALT4 in 223 CRC patient samples by immunohistochemistry and evaluated the po...

journal_title：World journal of gastroenterology

authors： Zhang T,Wang F,Wu JY,Qiu ZC,Wang Y,Liu F,Ge XS,Qi XW,Mao Y,Hua D

更新日期：2018-08-21 00:00:00

abstract：AIM:To investigate the association between adiponectin levels and risk of colorectal adenoma and cancer (early and advanced). METHODS:A cross-sectional study in a cohort of hospital-based patients was conducted between January 2004 and March 2006 at Yamagata University Hospital. Male subjects, who had colorectal tumor...

journal_title：World journal of gastroenterology

authors： Otake S,Takeda H,Fujishima S,Fukui T,Orii T,Sato T,Sasaki Y,Nishise S,Kawata S

更新日期：2010-03-14 00:00:00

abstract：AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

journal_title：World journal of gastroenterology

authors： Ding LA,Li JS

更新日期：2003-06-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is a critical risk factor for the carcinogenesis and progression of hepatocellular carcinoma (HCC). It promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Effective antiviral treatments...

journal_title：World journal of gastroenterology

authors： Zhang YQ,Guo JS

更新日期：2015-04-07 00:00:00

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00

abstract：AIM:To determine whether aspirin or non-aspirin non-steroidal anti-inflammatory drugs (NA-NSAIDs) prevent colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD). METHODS:We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD relate...

journal_title：World journal of gastroenterology

authors： Burr NE,Hull MA,Subramanian V

更新日期：2016-04-07 00:00:00

abstract：:Transplantation cannot be considered the most important therapeutic procedure for hepatocellular carcinoma (HCC). In France, no more than 2% of patients with HCC undergo a transplantation. Randomized controlled trial must assess the benefit to risk ratio of various potentially "curative" treatment procedures (transpla...

journal_title：World journal of gastroenterology

authors： Braillon A

更新日期：2009-11-14 00:00:00

abstract：AIM:To detect linc00675 expression in pancreatic ductal adenocarcinoma (PDAC), to analyze the relationship between the expression level of linc00675 and the clinical pathological characteristics, to explore the biological functions of linc00675, and to determine whether linc00675 has independent prognostic value in PDA...

journal_title：World journal of gastroenterology

authors： Li DD,Fu ZQ,Lin Q,Zhou Y,Zhou QB,Li ZH,Tan LP,Chen RF,Liu YM

更新日期：2015-08-21 00:00:00

abstract：AIM:To study the effects of palmatine, a known inhibitor on delayed rectifier potassium current and L-type calcium current (I(Ca,L)) in guinea pig ventricular myocytes, on the potassium and calcium currents in isolated rat hepatocytes. METHODS:Tight-seal whole-cell patch-clamp techniques were performed to investigate ...

journal_title：World journal of gastroenterology

authors： Wang F,Zhou HY,Cheng L,Zhao G,Zhou J,Fu LY,Yao WX

更新日期：2003-02-01 00:00:00

abstract：AIM:To investigate the effects of extended lymphadenectomy and postoperative chemotherapy on gastric cancer without lymph node metastasis. METHODS:Clinical data of 311 node-negative gastric cancer patients who underwent potentially curative gastrectomy with more than 15 lymph nodes resected, from January 2002 to Decem...

journal_title：World journal of gastroenterology

authors： Xue Q,Wang XN,Deng JY,Zhang RP,Liang H

更新日期：2013-09-07 00:00:00

abstract：:Understanding the occurrence, development, and treatment of liver diseases is the main goal of hepatopathology research. Liver diseases are not only diverse but also highly heterogeneous among individuals. At present, research on liver diseases is conducted mainly through cell culture, animal models, pathological spec...

journal_title：World journal of gastroenterology

authors： Wu LJ,Chen ZY,Wang Y,Zhao JG,Xie XZ,Chen G

更新日期：2019-04-28 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a chronic condition affecting 3%-25% of the general population. As no curative treatment is available, therapy is aimed at reducing symptoms, often with little success. Because alteration of the normal intestinal microflora has been observed in IBS, probiotics (beneficial microbes tak...

journal_title：World journal of gastroenterology

authors： McFarland LV,Dublin S

更新日期：2008-05-07 00:00:00

abstract：AIM:To study the expression and serum level of HBxAg, Fas and FasL in tissues of HCC patients, and to assess the relationship between HBxAg and Fas/FasL system. METHODS:Tissues from 50 patients with HCC were tested for the expression of HBxAg, Fas and FasL by S-P immunohistochemistry. Serum levels of sFas/sFasL and HB...

journal_title：World journal of gastroenterology

authors： Wang XZ,Chen XC,Chen YX,Zhang LJ,Li D,Chen FL,Chen ZX,Chen HY,Tao QM

更新日期：2003-12-01 00:00:00

abstract：AIM:To summarize progress in the study of K-ras gene studies in pancreatic cancer and its potential clinical significance in screening test for early detection of pancreatic cancer, and to differentiate pancreatic cancer from chronic pancreatitis in recent decade. METHODS:Literature search (MEDLINE 1986-2003) was perf...

journal_title：World journal of gastroenterology

authors： Mu DQ,Peng YS,Xu QJ

更新日期：2004-02-15 00:00:00

abstract：:Gastric cancer (GC) is one of the leading causes of cancer death in the world. Numerous efforts are being made to find chemoprotective agents able to reduce its risk. Amongst these, green tea has been reported to have a protective effect against stomach cancer. This article aims to critically evaluate all epidemiologi...

journal_title：World journal of gastroenterology

authors： Hou IC,Amarnani S,Chong MT,Bishayee A

更新日期：2013-06-28 00:00:00

abstract：:Adult to adult living donor liver transplantation (AALDLT) was first preformed in the United States in 1997. The procedure was rapidly integrated into clinical practice, but in 2002, possibly due to the first widely publicized donor death, the number of living liver donors plummeted. The number of donors has since rea...

journal_title：World journal of gastroenterology

authors： Carlisle EM,Testa G

更新日期：2012-12-14 00:00:00

abstract：AIM:To systematically review literature addressing three key psychologically-oriented controversies associated with gastroparesis. METHODS:A comprehensive search of PubMed, CINAHL, and PsycINFO databases was performed to identify literature addressing the relationship between gastroparesis and psychological factors. T...

journal_title：World journal of gastroenterology

authors： Woodhouse S,Hebbard G,Knowles SR

更新日期：2017-02-21 00:00:00

abstract：AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth. METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability ...

journal_title：World journal of gastroenterology

authors： Habbel P,Weylandt KH,Lichopoj K,Nowak J,Purschke M,Wang JD,He CW,Baumgart DC,Kang JX

更新日期：2009-03-07 00:00:00

abstract：:The liver is one of the most important organs in the body, performing a fundamental role in the regulation of diverse processes, among which the metabolism, secretion, storage, and detoxification of endogenous and exogenous substances are prominent. Due to these functions, hepatic diseases continue to be among the mai...

journal_title：World journal of gastroenterology

authors： Madrigal-Santillán E,Madrigal-Bujaidar E,Álvarez-González I,Sumaya-Martínez MT,Gutiérrez-Salinas J,Bautista M,Morales-González Á,García-Luna y González-Rubio M,Aguilar-Faisal JL,Morales-González JA

更新日期：2014-10-28 00:00:00

abstract：:AIM:To study the relationship between insulin A chain regions and insulin biological activities, we designed a series of insulin analogues with changes at A21, A12-18 of C terminal helical region and A8-10 located in the region of A6-A11 intra-chain disulphide bond.METHODS:Insulin A-chain analogues were prepared by st...

journal_title：World journal of gastroenterology

authors： Yang SZ,Huang YD,Jie XF,Feng YM,Niu JY

更新日期：2000-06-01 00:00:00

abstract：:There was remarkable progress in the understanding of the role genetic risk factors in chronic pancreatitis. These factors seem to be much more important than thought in the past. The rare autosomal-dominant mutations N29I and R122H of PRSS1 (cationic trypsinogen) as well as the variant N34S of SPINK1 (pancreatic secr...

journal_title：World journal of gastroenterology

authors： Keim V

更新日期：2008-02-21 00:00:00

abstract：:Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome. She was diagnosed with Proteus syndrome based on certain diagnostic criteria. The neoplasm increased ...

journal_title：World journal of gastroenterology

authors： Nakayama Y,Kusuda S,Nagata N,Yamaguchi K

更新日期：2009-07-14 00:00:00