Review of natural products with hepatoprotective effects.

abstract：AIM:To investigate the effect of Danzhijiangtang capsule (DJC) on monocyte chemoattractant protein-1 (MCP-1) mRNA expression in newly diagnosed type 2 diabetes mellitus (T2DM) subclinical vascular lesions. METHODS:Sixty-two patients with newly diagnosed T2DM subclinical vascular lesions were randomly divided into a co...

journal_title：World journal of gastroenterology

authors： Fang ZH,Liu Y,Bao TT,Ni YQ,Liu J,Shi GB,Wu JP,Yang JP,Zhang H

更新日期：2013-05-21 00:00:00

abstract：AIM:To demonstrate the possible associations between genetic polymorphisms of aldehyde dehydrogenase-2 (ALDH2) and esophageal squamous cell dysplasia (ESCD). METHODS:All participants came from an area of high incidence of esophageal cancer and underwent an endoscopic staining examination; biopsies were taken from a no...

journal_title：World journal of gastroenterology

authors： Zhou YZ,Diao YT,Li H,Li HQ,Ma Q,Cui J

更新日期：2010-07-21 00:00:00

abstract：:This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous ...

journal_title：World journal of gastroenterology

authors： Luo X,Li W,Bird N,Chin SB,Hill NA,Johnson AG

更新日期：2007-03-07 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic granulomatous, and destructive inflammatory lesion of small intralobular and septal bile ducts, which is likely to be caused by an autoimmune mechanism with a the presence of serum antimitochondrial antibodies and a potential tendency to progress to ...

journal_title：World journal of gastroenterology

authors： Reshetnyak VI

更新日期：2015-07-07 00:00:00

abstract：AIM:To determine the immune-modulatory and the hepatoprotective effects of oral administration of two soy extracts in immune mediated liver injury and non-alcoholic steatohepatitis (NASH). METHODS:Two soy extracts, M1 and OS, were orally administered to mice with concanavalin A (ConA) immune-mediated hepatitis, to hig...

journal_title：World journal of gastroenterology

authors： Khoury T,Ben Ya'acov A,Shabat Y,Zolotarovya L,Snir R,Ilan Y

更新日期：2015-06-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a dismal prognosis, especially when diagnosed at advanced stages. Annexin A2 (ANXA2), is found to promote cancer progression and therapeutic resistance. However, the underlining mechanisms of ANXA2 in immune escape of HCC remain poorly underst...

journal_title：World journal of gastroenterology

authors： Qiu LW,Liu YF,Cao XQ,Wang Y,Cui XH,Ye X,Huang SW,Xie HJ,Zhang HJ

更新日期：2020-05-14 00:00:00

abstract：AIM:To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS:We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding t...

journal_title：World journal of gastroenterology

authors： Enns RA,Gagnon YM,Barkun AN,Armstrong D,Gregor JC,Fedorak RN,RUGBE Investigators Group.

更新日期：2006-12-28 00:00:00

abstract：AIM:To study the protein C activation system in human liver myofibroblasts, and the effects of activated protein C (APC) on these cells. METHODS:Human liver myofibroblasts were obtained by outgrowth. Expression of protease activated receptor 1 (PAR-1), endothelial protein C receptor (EPCR) and thrombomodulin (TM) was ...

journal_title：World journal of gastroenterology

authors： Gillibert-Duplantier J,Rullier A,Neaud V,Kisiel W,Rosenbaum J

更新日期：2010-01-14 00:00:00

abstract：:Liver transplantation for human immunodeficiency virus (HIV) positive patients with viral hepatitis co-infection is increasingly offered in many North American and European liver transplant centers. Prior studies have demonstrated acceptable post-transplant outcomes and no increased risk of HIV complications in patien...

journal_title：World journal of gastroenterology

authors： Congly SE,Doucette KE,Coffin CS

更新日期：2014-01-14 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：AIM:To accurately and realistically elucidate human stem cell behaviors in vivo and the fundamental mechanisms controlling human stem cell fates in vivo, which is urgently required in regenerative medicine and treatments for some human diseases, a surrogate human-rat chimera model was developed. METHODS:Human-rat chim...

journal_title：World journal of gastroenterology

authors： Sun Y,Xiao D,Pan XH,Zhang RS,Cui GH,Chen XG

更新日期：2007-05-21 00:00:00

abstract：:Metastatic colorectal cancer (mCRC) continues to be counted as a major health problem. The introduction of newer cytotoxics, irinotecan and oxaliplatin, has achieved a significant improvement in survival rates. Novel targeted therapies (bevacizumab, and cetuximab) in combination with most efficient chemotherapy regime...

journal_title：World journal of gastroenterology

authors： Saridaki Z,Georgoulias V,Souglakos J

更新日期：2010-03-14 00:00:00

abstract：AIM:To study the protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury and its mechanism after hemorrhagic shock in rats. METHODS:A total of 32 SD rats were randomly divided into four groups (n = 8, each group): normal group, model group, low dosage group (treated with 10 g/kg Astragalus...

journal_title：World journal of gastroenterology

authors： Hei ZQ,Huang HQ,Zhang JJ,Chen BX,Li XY

更新日期：2005-08-28 00:00:00

abstract：AIM:To prospectively evaluate the effectiveness and safety of continuous wound infiltration (CWI) for pain management after open gastrectomy. METHODS:Seventy-five adult patients with American Society of Anesthesiologists (ASA) Physical Status Classification System (ASA) grade 1-3 undergoing open gastrectomy were rando...

journal_title：World journal of gastroenterology

authors： Zheng X,Feng X,Cai XJ

更新日期：2016-02-07 00:00:00

abstract：:Examinations with a visualisation of the anatomy and pathology of the gastrointestinal (GI) tract are often necessary for the diagnosis of GI diseases. Traditional radiology played a crucial role for many years. Endoscopy, despite some limitations, remains the main technique in the differential diagnosis and treatment...

journal_title：World journal of gastroenterology

authors： Roccarina D,Garcovich M,Ainora ME,Caracciolo G,Ponziani F,Gasbarrini A,Zocco MA

更新日期：2013-01-01 00:00:00

abstract：AIM:To analyze the effects of premedication with Pronase for endoscopic ultrasound (EUS) examination of the stomach. METHODS:This was a prospective, randomized and controlled clinical study. All patients were randomly assigned to either the Pronase group or placebo group. The pretreatment solution was a mixed solution...

journal_title：World journal of gastroenterology

authors： Wang GX,Liu X,Wang S,Ge N,Guo JT,Sun SY

更新日期：2016-12-28 00:00:00

abstract：AIM:To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS:The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli U...

journal_title：World journal of gastroenterology

authors： Hulagu S,Senturk O,Aygun C,Kocaman O,Celebi A,Konduk T,Koc D,Sirin G,Korkmaz U,Duman AE,Bozkurt N,Dindar G,Attila T,Gurbuz Y,Tarcin O,Kalayci C

更新日期：2011-04-07 00:00:00

abstract：:Single-incision laparoscopic surgery (SILS) and natural orifice transluminal endoscopic surgery (NOTES) have rapidly gained pace worldwide, potentially replacing conventional laparoscopic surgery (CLS) as the preferred colorectal surgery technique. Currently available data mainly consist of retrospective series analyz...

journal_title：World journal of gastroenterology

authors： Daher R,Chouillard E,Panis Y

更新日期：2014-12-28 00:00:00

abstract：:A 52 year-old male patient diagnosed of ankylosing spondylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate. He did not respond to treatment with oral iron not a proton pump inhibitor and an upper endoscopy was performed. The histological study of the duodenal biopsies showed vi...

journal_title：World journal of gastroenterology

authors： Boscá MM,Añón R,Mayordomo E,Villagrasa R,Balza N,Amorós C,Corts JR,Benages A

更新日期：2008-12-07 00:00:00

abstract：AIM:To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma and therapeutic outcome. METHODS:Purified anti-CEA monoclonal antibody (McAb) was biotinylated with NHS-biotin, and then radiolabeled with 188Re by the direct method. 188Re-labeled b...

journal_title：World journal of gastroenterology

authors： Li GP,Wang YX,Huang K,Zhang H,Zhang CF

更新日期：2005-04-07 00:00:00

abstract：AIM:Trace elements (TE) metabolism is altered in inflammatory bowel diseases. TE (zinc and copper) are constituents of antioxidant enzymes. Iron is involved in the pathogenesis of chronic inflammation. The aim was to evaluate zinc and copper status and the effects of iron manipulation in experimental colitis. METHODS:...

journal_title：World journal of gastroenterology

authors： Barollo M,D'Inca R,Scarpa M,Medici V,Cardin R,Bortolami M,Ruffolo C,Angriman I,Sturniolo GC

更新日期：2005-07-28 00:00:00

abstract：AIM:To evaluate the proinflammatory effects and molecular mechanisms of interleukin (IL)-17 in intestinal epithelial cell line HT-29. METHODS:HT-29 cells were cultured with IL-17, tumor necrosis factor (TNF)-α, or the combination of both IL-17 and TNF-α. Real-time PCR and Western blot were used to measure the gene exp...

journal_title：World journal of gastroenterology

authors： Wang YL,Fang M,Wang XM,Liu WY,Zheng YJ,Wu XB,Tao R

更新日期：2014-12-21 00:00:00

abstract：AIM:As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in...

journal_title：World journal of gastroenterology

authors： Yin ZY,Ni XD,Jiang F,Li N,Li YS,Li JS

更新日期：2003-07-01 00:00:00

abstract：:Surgery represents the main curative therapeutic modality for gastric cancer, and it is occasionally considered for palliation as well as prophylaxis. Most frequently, surgical outcomes are conveyed in terms of oncological outcomes such as recurrence and survival. However, quality of life (QoL) is also important and s...

journal_title：World journal of gastroenterology

authors： McCall MD,Graham PJ,Bathe OF

更新日期：2016-01-21 00:00:00

abstract：AIM:To explore the contribution of AXIN1, AXIN2 and beta-catenin, components of Wnt signaling pathway, to the carcinogenesis of gastric cancer (GC), we examined AXIN1, AXIN2 exon7 and CTNNB1 (encoding beta-catenin) exon3 mutations in 70 GCs. METHODS:The presence of mutations was identified by polymerase chain reaction...

journal_title：World journal of gastroenterology

authors： Pan KF,Liu WG,Zhang L,You WC,Lu YY

更新日期：2008-03-14 00:00:00

abstract：AIM:To investigate the effects of combined use of emodin and baicalein (CEB) at the cellular and organism levels in severe acute pancreatitis (SAP) and explore the underlying mechanism. METHODS:SAP was induced by retrograde infusion of 5% sodium taurocholate into the pancreatic duct in 48 male SD rats. Pancreatic hist...

journal_title：World journal of gastroenterology

authors： Li J,Zhou R,Bie BB,Huang N,Guo Y,Chen HY,Shi MJ,Yang J,Zhang J,Li ZF

更新日期：2018-01-07 00:00:00

abstract：AIM:To assess the practice of caring for acute liver failure (ALF) patients in varying geographic locations and medical centers. METHODS:Members of the European Acute Liver Failure Consortium completed an 88-item questionnaire detailing management of ALF. Responses from 22 transplantation centers in 11 countries were ...

journal_title：World journal of gastroenterology

authors： Rabinowich L,Wendon J,Bernal W,Shibolet O

更新日期：2016-09-07 00:00:00

abstract：AIM:To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA). METHODS:WB-F344 cells were continuously exposed to 7 x 10(-7) mol/L H2O2 for 21 d. Observations of cell morphology, colony formation rates, flow cyt...

journal_title：World journal of gastroenterology

authors： Han YY,Xue XW,Shi ZM,Wang PY,Wu XR,Wang XJ

更新日期：2014-02-07 00:00:00

abstract：AIM:To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn's disease (CD) intestinal fibrosis. METHODS:First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and select the optimal conc...

journal_title：World journal of gastroenterology

authors： Yang BL,Zhu P,Li YR,Xu MM,Wang H,Qiao LC,Xu HX,Chen HJ

更新日期：2018-08-14 00:00:00

abstract：AIM:We have previously demonstrated that cholangiocytes, the epithelial cells lining intrahepatic bile ducts, encode two functional bile acid transporters via alternative splicing of a single gene to facilitate bile acid vectorial transport. Cholangiocytes possess ASBT, an apical sodium-dependent bile acid transporter ...

journal_title：World journal of gastroenterology

authors： Kip NS,Lazaridis KN,Masyuk AI,Splinter PL,Huebert RC,LaRusso NF

更新日期：2004-05-15 00:00:00