Methotrexate induced sprue-like syndrome.

Abstract:

:A 52 year-old male patient diagnosed of ankylosing spondylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate. He did not respond to treatment with oral iron not a proton pump inhibitor and an upper endoscopy was performed. The histological study of the duodenal biopsies showed villus atrophy. After removing the methotrexate, administering intramuscular iron and undertaking a gluten-free diet, the histological and analytical alterations progressively resolved.

journal_name

World J Gastroenterol

authors

Boscá MM,Añón R,Mayordomo E,Villagrasa R,Balza N,Amorós C,Corts JR,Benages A

doi

10.3748/wjg.14.7009

subject

Has Abstract

pub_date

2008-12-07 00:00:00

pages

7009-11

issue

45

eissn

1007-9327

issn

2219-2840

journal_volume

14

pub_type

杂志文章
  • Characterization of hepatic progenitors from human fetal liver using CD34 as a hepatic progenitor marker.

    abstract:AIM:To enrich putative hepatic progenitors from the developing human fetal liver using CD34 as a marker. METHODS:Aborted fetuses of 13-20 wk were used for the isolation of liver cells. The cells were labeled with anti CD34; a marker used for isolating progenitor population and the cells were sorted using magnetic cell...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i16.2319

    authors: Nyamath P,Alvi A,Habeeb A,Khosla S,Khan AA,Habibullah CM

    更新日期:2007-04-28 00:00:00

  • Neoadjuvant chemoradiotherapy followed by D2 gastrectomy in locally advanced gastric cancer.

    abstract:AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy (NACRT) for resectability of locally advanced gastric cancer (LAGC). METHODS:Between November 2007 and January 2014, 29 patients with LAGC (clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT fo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i9.2711

    authors: Kim MS,Lim JS,Hyung WJ,Lee YC,Rha SY,Keum KC,Koom WS

    更新日期:2015-03-07 00:00:00

  • Constant serum levels of secreted asialoglycoprotein receptor sH2a and decrease with cirrhosis.

    abstract:AIM:To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS:Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentrati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i48.5305

    authors: Benyair R,Kondratyev M,Veselkin E,Tolchinsky S,Shenkman M,Lurie Y,Lederkremer GZ

    更新日期:2011-12-28 00:00:00

  • Tumor necrosis factor-α inhibitors and chronic hepatitis C: a comprehensive literature review.

    abstract::Tumor necrosis factor-α (TNF-α) inhibitors are known to increase reactivation of concurrent chronic hepatitis B, but their impact on the hepatitis C virus (HCV) is controversial. Some conditions of immunosuppression, such as liver transplantation, typically cause an increase in the rate of HCV evolution. Inhibition of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i44.7867

    authors: Pompili M,Biolato M,Miele L,Grieco A

    更新日期:2013-11-28 00:00:00

  • Small intestinal vascular malformation bleeding: a case report with imaging findings.

    abstract::The small intestine is approximately 5-6 m long and occupies a large area in the abdominal cavity. These factors preclude the use of ordinary endoscopy and X-ray to thoroughly examine the small intestine for bleeding of vascular malformations. Thus, the diagnosis of intestinal bleeding is very difficult. A 47-year-old...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i38.14076

    authors: Cui J,Huang LY,Lin SJ,Yi LZ,Wu CR,Zhang B

    更新日期:2014-10-14 00:00:00

  • Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: effect of bombesin and neurotensin.

    abstract:AIM:To investigate the influence of experimental obstructive jaundice and exogenous bombesin (BBS) and neurotensin (NT) administration on the expression of the tight junction (TJ)-protein claudin-4 in intestinal epithelium of rats. METHODS:Forty male Wistar rats were randomly divided into five groups: I = controls, II...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i21.3410

    authors: Assimakopoulos SF,Vagianos CE,Charonis AS,Alexandris IH,Spiliopoulou I,Thomopoulos KC,Nikolopoulou VN,Scopa CD

    更新日期:2006-06-07 00:00:00

  • Expression of vascular endothelial growth factors A and C in human pancreatic cancer.

    abstract:AIM:To study the expression of vascular endothelial growth factor A (VEGF-A) and VEGF-C and to determine whether the presence of VEGF-A and VEGF-C was associated with the clinicopathologic characteristics of pancreatic cancer. METHODS:VEGF-A and VEGF-C mRNA transcripts were examined by Northern blot in 6 human pancrea...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i2.280

    authors: Tang RF,Wang SX,Peng L,Wang SX,Zhang M,Li ZF,Zhang ZM,Xiao Y,Zhang FR

    更新日期:2006-01-14 00:00:00

  • Recent advances in pharmacological treatment of irritable bowel syndrome.

    abstract::Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients' quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i27.8867

    authors: Lazaraki G,Chatzimavroudis G,Katsinelos P

    更新日期:2014-07-21 00:00:00

  • Crohn's disease complicated by multiple stenoses and internal fistulas clinically mimicking small bowel endometriosis.

    abstract::We report a 31-year-old woman with Crohn's disease complicated by multiple stenoses and internal fistulas clinically misdiagnosed as small bowel endometriosis, due to the patient's perimenstrual symptoms of mechanical subileus for 3 years; at first monthly, but later continuous, and gradually increasing in severity. W...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.146

    authors: Teke Z,Aytekin FO,Atalay AO,Demirkan NC

    更新日期:2008-01-07 00:00:00

  • Extensive calcifications in portal venous system in a patient with hepatocarcinoma.

    abstract::Calcification of the portal venous system is a rare entity that can be incidentally discovered during computed tomography (CT). We describe a case of extensive calcifications in the portal venous system in a middle-aged male patient with hepatocellular carcinoma (HCC). This patient presented with epigastric pain that ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i43.16377

    authors: Wang CE,Sun CJ,Huang S,Wang YH,Xie LL

    更新日期:2014-11-21 00:00:00

  • Detection of hepatitis B virus genotypes using oligonucleotide chip among hepatitis B virus carriers in Eastern China.

    abstract:AIM:To determine the genotype distribution of hepatitis B virus (HBV) with a newly oligonucleotide chip assay among the HBV carriers in Eastern China. METHODS:An assay using oligonucleotide chip was developed for detection of HBV genotypes in serum samples from HBV DNA-positive patients in Eastern China. This method i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v13.i13.1975

    authors: Tang XR,Zhang JS,Zhao H,Gong YH,Wang YZ,Zhao JL

    更新日期:2007-04-07 00:00:00

  • Confocal laser endomicroscopy in inflammatory bowel diseases: dream or reality?

    abstract::Confocal laser endomicroscopy (CLE) is a newly introduced procedure that provide real-time, high-resolution imaging of the gastrointestinal mucosa during endoscopy, allowing the visualization of the pathology of the mucosal epithelium with its cellular and subcellular structures. Recently, the use of CLE was reported ...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v19.i34.5593

    authors: De Palma GD,Rispo A

    更新日期:2013-09-14 00:00:00

  • Extraintestinal manifestations in inflammatory bowel disease.

    abstract::Inflammatory bowel diseases (IBD) can be really considered to be systemic diseases since they are often associated with extraintestinal manifestations, complications, and other autoimmune disorders. Indeed, physicians who care for patients with ulcerative colitis and Crohn's disease, the two major forms of IBD, face a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v11.i46.7227

    authors: Danese S,Semeraro S,Papa A,Roberto I,Scaldaferri F,Fedeli G,Gasbarrini G,Gasbarrini A

    更新日期:2005-12-14 00:00:00

  • Construction of targeted plasmid vector pcDNA3.1-Egr.1p-p16 and its expression in pancreatic cancer JF305 cells induced by radiation in vitro.

    abstract:AIM:To construct pcDNA3.1-Egr.1p-p16 recombinant plasmid and investigate the expression of p16 in pancreatic cancer JF305 cells induced by radiation and the feasibility of gene radiotherapy for pancreatic carcinoma. METHODS:Human p16 cDNA was ligated to the downstream of Egr-1 promotor to construct pcDNA3.1-Egr.1p-p16...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i31.4214

    authors: Ma HB,Wang XJ,Di ZL,Xia H,Li Z,Liu J,Ma J,Kang HF,Wu CM,Bai MH

    更新日期:2007-08-21 00:00:00

  • Dynamic changes of key metabolites during liver fibrosis in rats.

    abstract:BACKGROUND:Fibrosis is the single most important predictor of significant morbidity and mortality in patients with chronic liver disease. Established non-invasive tests for monitoring fibrosis are lacking, and new biomarkers of liver fibrosis and function are needed. AIM:To depict the process of liver fibrosis and loo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i8.941

    authors: Yu J,He JQ,Chen DY,Pan QL,Yang JF,Cao HC,Li LJ

    更新日期:2019-02-28 00:00:00

  • Management of recurrent rectal cancer: a population based study in greater Amsterdam.

    abstract:AIM:To analyze, retrospectively in a population-based study, the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS:All rectal carcinomas diagnosed during 1998 to 2000 and initially treated w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.6018

    authors: Bakx R,Visser O,Josso J,Meijer S,Slors JF,van Lanschot JJ

    更新日期:2008-10-21 00:00:00

  • Associations between NOD2/CARD15 genotype and phenotype in Crohn's disease--Are we there yet?

    abstract::There have been multiple NOD2/CARD15 genotype-phenotype analyses undertaken in patients with Crohn's disease since the gene's discovery in 2001. This review focuses on the major published series based upon their size and on the presence of specific clinical and genetic information provided in the published material fr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.v12.i44.7097

    authors: Radford-Smith G,Pandeya N

    更新日期:2006-11-28 00:00:00

  • Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease.

    abstract:AIM:To investigate the relationship between sense of coherence, psychological distress and health related quality of life in inflammatory bowel disease (IBD). METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD (aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroente...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i21.6713

    authors: Freitas TH,Andreoulakis E,Alves GS,Miranda HL,Braga LL,Hyphantis T,Carvalho AF

    更新日期:2015-06-07 00:00:00

  • Effect of NDC80 in human hepatocellular carcinoma.

    abstract:AIM:To investigate the role of nuclear division cycle (NDC)80 in human hepatocellular carcinogenesis. METHODS:NDC80 gene expression was analyzed by real-time reverse transcription polymerase chain reaction in 47 paired hepatocellular carcinoma (HCC) and adjacent tissues. The HCC cell line SMMC-7721 was transfected wit...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i20.3675

    authors: Ju LL,Chen L,Li JH,Wang YF,Lu RJ,Bian ZL,Shao JG

    更新日期:2017-05-28 00:00:00

  • Mucosal blood flow measurements using laser Doppler perfusion monitoring.

    abstract::Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insufficiency of perfusion, is a common mechanism for tissue death or degeneration, and at a lower threshold, a mechanism for the generation of sensory signallin...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.198

    authors: Hoff DA,Gregersen H,Hatlebakk JG

    更新日期:2009-01-14 00:00:00

  • Case of pediatric traditional serrated adenoma resected via endoscopic submucosal dissection.

    abstract::Traditional serrated adenoma (TSA) is a type of serrated polyp of the colorectum and is thought to be a precancerous lesion. There are three types of serrated polyps, namely, hyperplastic polyps, sessile serrated adenomas/polyps, and TSAs. TSA is the least common of the three types and accounts for about 5% of serrate...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i24.4462

    authors: Kondo S,Mori H,Nishiyama N,Kondo T,Shimono R,Okada H,Kusaka T

    更新日期:2017-06-28 00:00:00

  • Effect of NLRC5 on activation and reversion of hepatic stellate cells by regulating the nuclear factor-κB signaling pathway.

    abstract:BACKGROUND:The formation of liver fibrosis is mainly caused by the activation of hepatic stellate cells (HSCs) and the imbalance of extracellular matrix (ECM) production and degradation. The treatment of liver fibrosis mainly includes removing the cause, inhibiting the activation of HSCs, and inhibiting inflammation. N...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i24.3044

    authors: Zhang YZ,Yao JN,Zhang LF,Wang CF,Zhang XX,Gao B

    更新日期:2019-06-28 00:00:00

  • Superior mesenteric artery syndrome following scoliosis surgery: its risk indicators and treatment strategy.

    abstract:AIM:To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery. METHODS:From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and am...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i21.3307

    authors: Zhu ZZ,Qiu Y

    更新日期:2005-06-07 00:00:00

  • Effects of herbal compound 861 on human hepatic stellate cell proliferation and activation.

    abstract:AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i19.2831

    authors: Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

    更新日期:2004-10-01 00:00:00

  • Antioxidative status of patients with alcoholic liver disease in southeastern Taiwan.

    abstract:AIM:To investigate the antioxidative status of patients with alcoholic liver disease (ALD) in southeastern Taiwan. METHODS:Our study comprised 27 patients with ALD recruited from Taitung Mackay Memorial Hospital, located in southeastern Taiwan. Patients with ALD included 12 non-aborigines (12 men) and 15 aborigines (1...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i8.1063

    authors: Chen YL,Chen LJ,Bair MJ,Yao ML,Peng HC,Yang SS,Yang SC

    更新日期:2011-02-28 00:00:00

  • Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China.

    abstract:AIM:To evaluate whether alcohol dehydrogenase-1B (ADH1B) His47Arg and aldehyde dehydrogenase-2 (ALDH2) Glu487Lys polymorphism is involved in the esophageal squamous cell carcinoma (ESCC) risk in Chinese Han population. METHODS:Seven studies of ADH1B and ALDH2 genotypes in Chinese Han population in 1450 cases and 2459 ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v16.i47.6020

    authors: Zhang GH,Mai RQ,Huang B

    更新日期:2010-12-21 00:00:00

  • Commercially available probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea.

    abstract:AIM:To investigate the effect of Lactobacillus-containing commercially available probiotic formulations in Germany during antibiotic treatment with an analysis of cost-efficiency. METHODS:In an observational study, we analyzed the frequency of bowel movements from 258 patients with infections in a primary care hospita...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v20.i42.15837

    authors: Dietrich CG,Kottmann T,Alavi M

    更新日期:2014-11-14 00:00:00

  • Methodology for high-quality studies on course and prognosis of inflammatory bowel disease.

    abstract::Inflammatory bowel diseases (IBDs) are characterized by a chronic course with an alternation of relapses and remissions. Questions about prognosis are important for the patient who wants to know how the disease will affect his/her life and also for clinicians to make management decisions. Correct selection of the pati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v18.i29.3800

    authors: Modesto I,Perricone G,Orlando A,Cottone M

    更新日期:2012-08-07 00:00:00

  • Repeat endoscopic retrograde cholangiopancreaticography after failed initial precut sphincterotomy for biliary cannulation.

    abstract:AIM:To investigate the outcome of repeating endoscopic retrograde cholangiopancreaticography (ERCP) after initially failed precut sphincterotomy to achieve biliary cannulation. METHODS:In this retrospective study, consecutive ERCPs performed between January 2009 and September 2012 were included. Data from our endoscop...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i36.13153

    authors: Pavlides M,Barnabas A,Fernandopulle N,Bailey AA,Collier J,Phillips-Hughes J,Ellis A,Chapman R,Braden B

    更新日期:2014-09-28 00:00:00

  • Pulmonary manifestations of inflammatory bowel disease.

    abstract::Extraintestinal manifestations of inflammatory bowel disease (IBD) are a systemic illness that may affect up to half of all patients. Among the extraintestinal manifestations of IBD, those involving the lungs are relatively rare and often overlooked. However, there is a wide array of such manifestations, spanning from...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i37.13501

    authors: Ji XQ,Wang LX,Lu DG

    更新日期:2014-10-07 00:00:00