Oleanolic acid and ursolic acid inhibit proliferation in transformed rat hepatic oval cells.

abstract：:The evasion from controlled cell death induction has been considered as one of the hallmarks of cancer cells. Defects in cell death signaling are a fundamental phenomenon in colorectal cancer. Nearly any non-invasive cancer treatment finally aims to induce cell death. However, apoptosis resistance is the major cause f...

journal_title：World journal of gastroenterology

authors： Koehler BC,Jäger D,Schulze-Bergkamen H

更新日期：2014-02-28 00:00:00

abstract：AIM:To evaluate when Helicobacter pylori (H. pylori) eradication therapy (ET) should be started in patients with peptic ulcer bleeding (PUB). METHODS:Clinical data concerning adults hospitalized with PUB were retrospectively collected and analyzed. Age, sex, type and stage of peptic ulcer, whether endoscopic therapy w...

journal_title：World journal of gastroenterology

authors： Yoon H,Lee DH,Jang ES,Kim J,Shin CM,Park YS,Hwang JH,Kim JW,Jeong SH,Kim N

更新日期：2015-02-28 00:00:00

abstract：AIM:To prepare and characterize polyclonal antibodies against aldose reductase-like (ARL-1) protein. METHODS:ARL-1 gene was inserted into the E. coli expression vector pGEX-4T-1(His)(6)C and vector pQE-30. Recombinant ARL-1 proteins named ARL-(His)(6) and ARL-GST were expressed. They were purified by affinity chromato...

journal_title：World journal of gastroenterology

authors： Jin JF,Yuan LD,Liu L,Zhao ZJ,Xie W

更新日期：2003-07-01 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterized by progressive bile duct destruction eventually leading to cirrhosis and liver failure. The serological hallmark of the disease is the presence of circulating antimitochondrial antibodies (AMA). These reflect the presence of autoreacti...

journal_title：World journal of gastroenterology

authors： Lleo A,Invernizzi P,Mackay IR,Prince H,Zhong RQ,Gershwin ME

更新日期：2008-06-07 00:00:00

abstract：:Coeliac disease (CD) is a complex condition resulting from an interplay between genetic and environmental factors. When diagnosing the condition, serological testing and genotyping are useful in excluding CD, although the gold standard of testing is currently histopathological examination of the small intestine. There...

journal_title：World journal of gastroenterology

authors： Charlesworth RP

更新日期：2020-01-07 00:00:00

abstract：:Liver cancer is one of the world's most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma (HCC), a primary hepatic cancer, accounts for 90%-95% of liver cancer cases. The pathogenesis of HCC consists of a stepwise process of liver damage that extends over decades, due to hepatitis,...

journal_title：World journal of gastroenterology

authors： Lu JW,Ho YJ,Yang YJ,Liao HA,Ciou SC,Lin LI,Ou DL

更新日期：2015-11-14 00:00:00

abstract：:Calcification of the portal venous system is a rare entity that can be incidentally discovered during computed tomography (CT). We describe a case of extensive calcifications in the portal venous system in a middle-aged male patient with hepatocellular carcinoma (HCC). This patient presented with epigastric pain that ...

journal_title：World journal of gastroenterology

authors： Wang CE,Sun CJ,Huang S,Wang YH,Xie LL

更新日期：2014-11-21 00:00:00

abstract：:AIM:To construct Hsp90 antisense RNA eukaryotic expression vector, transfect it into SGC7901 and SGC7901/VCR of MDR-type human gastric cancer cell lines, HCC7402 of human hepatic cancer and Ec109 of human esophageal cancer cell lines, and to study the cell cycle distribution of the gene transected cells and their resp...

journal_title：World journal of gastroenterology

authors： Liu XL,Xiao B,Yu ZC,Guo JC,Zhao QC,Xu L,Shi YQ,Fan DM

更新日期：1999-06-01 00:00:00

abstract：AIM:To explore the diffusion gradient b-factor that optimizes both apparent diffusion coefficient (ADC) measurement and contrast-to-noise (CNR) for assessing tumor response to transarterial chemoembolization (TACE) in a rabbit model. METHODS:Twelve New Zealand white rabbits bearing VX2 tumors in the liver were treated...

journal_title：World journal of gastroenterology

authors： Jiang ZX,Peng WJ,Li WT,Tang F,Liu SY,Qu XD,Wang JH,Lu HF

更新日期：2008-10-14 00:00:00

abstract：AIM:To assess the incidence and risk factors associated with colonic perforation due to colonoscopy. METHODS:This was a retrospective cross-sectional study. Patients were retrospectively eligible for inclusion if they were 18 years and older and had an inpatient or outpatient colonoscopy procedure code in any facility...

journal_title：World journal of gastroenterology

authors： Hamdani U,Naeem R,Haider F,Bansal P,Komar M,Diehl DL,Kirchner HL

更新日期：2013-06-21 00:00:00

abstract：AIM:To investigate the toxicity and response of intensity-modulated radiotherapy schedule intensified with a simultaneous integrated boost in anal canal cancer. METHODS:From March 2009 to March 2014, we retrospectively analyzed 41 consecutive patients treated with intensity-modulated radiotherapy (IMRT) and concurrent...

journal_title：World journal of gastroenterology

authors： Belgioia L,Vagge S,Agnese D,Garelli S,Murialdo R,Fornarini G,Chiara S,Gallo F,Bacigalupo A,Corvò R

更新日期：2015-10-07 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：:Sorafenib is the current standard treatment for advanced hepatocellular carcinoma (HCC), but its efficacy is modest with low response rates and short response duration. Predictive biomarkers for sorafenib efficacy are necessary. However, efforts to determine biomarkers for sorafenib have led only to potential candidat...

journal_title：World journal of gastroenterology

authors： Shao YY,Hsu CH,Cheng AL

更新日期：2015-09-28 00:00:00

abstract：:Hepatitis C virus (HCV) is one of the main etiological factors responsible for liver disease worldwide. It has been estimated that there are over 170 million people infected with HCV worldwide. Of these infected individuals, approximately 75% will go on to develop a life long necroinflammatory liver disease, which ove...

journal_title：World journal of gastroenterology

authors： McCartney EM,Beard MR

更新日期：2010-03-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary liver cancer with a dismal prognosis, especially when diagnosed at advanced stages. Annexin A2 (ANXA2), is found to promote cancer progression and therapeutic resistance. However, the underlining mechanisms of ANXA2 in immune escape of HCC remain poorly underst...

journal_title：World journal of gastroenterology

authors： Qiu LW,Liu YF,Cao XQ,Wang Y,Cui XH,Ye X,Huang SW,Xie HJ,Zhang HJ

更新日期：2020-05-14 00:00:00

abstract：AIM:To identify whether chitinase 3-like 1 (CHI3L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma (ESCC) and to analyze this protein's cellular source. METHODS:An ELISA was conducted to detect the concentration of CHI3L1 in the serum of 150 ESCC patients diagnosed between Janua...

journal_title：World journal of gastroenterology

authors： Xing S,Zheng X,Zeng T,Zeng MS,Zhong Q,Cao YS,Pan KL,Wei C,Hou F,Liu WL

更新日期：2017-11-21 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：AIM:To investigate the effect of quercetin supplementation on the myenteric neurons and glia in the cecum of diabetic rats. METHODS:Total preparations of the muscular tunic were prepared from the ceca of twenty-four rats divided into the following groups: control (C), control supplemented with quercetin (200 mg/kg que...

journal_title：World journal of gastroenterology

authors： Ferreira PE,Lopes CR,Alves AM,Alves ÉP,Linden DR,Zanoni JN,Buttow NC

更新日期：2013-10-14 00:00:00

abstract：AIM:To evaluate the best diagnostic technique and risk factors of the human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) infection in inflammatory bowel disease (IBD). METHODS:A cohort of 40 IBD patients (17 refractory) and 40 controls underwent peripheral blood and endoscopic colonic mucosal sample harvest. Vi...

journal_title：World journal of gastroenterology

authors： Ciccocioppo R,Racca F,Paolucci S,Campanini G,Pozzi L,Betti E,Riboni R,Vanoli A,Baldanti F,Corazza GR

更新日期：2015-02-14 00:00:00

abstract：AIM:To compare the prevalence of Helicobacter pylori (H pylori) IgG and IgA antibodies between adult subjects, with defined gastric diseases, non-defined gastric disorders and those representing the population. METHODS:Data on H pylori IgG and IgA antibodies, determined by enzyme immunoassay, were analyzed in 3,252 su...

journal_title：World journal of gastroenterology

authors： Kosunen TU,Seppala K,Sarna S,Aromaa A,Knekt P,Virtamo J,Salomaa-Rasanen A,Rautelin H

更新日期：2005-11-21 00:00:00

abstract：AIM:To examine whether a dose-up to 900 mg of ursodeoxycholic acid (UDCA) decreases transaminases in hepatitis C patients. METHODS:From January to December 2007, patients with chronic hepatitis C or compensated liver cirrhosis with hepatitis C virus (HCV) (43-80 years old) showing positive serum HCV-RNA who had alread...

journal_title：World journal of gastroenterology

authors： Sato S,Miyake T,Tobita H,Oshima N,Ishine J,Hanaoka T,Amano Y,Kinoshita Y

更新日期：2009-06-14 00:00:00

abstract：AIM:To investigate the role of single nucleotide polymorphisms (SNPs) in CD24 gene in susceptibility and overall survival of gastric cancer (GC). METHODS:We genotyped 3 tagging SNPs of CD24-P-534 in the promoter region, P170 in the coding region of exon 2 and P1527 in the 3' untranslated region - using polymerase chai...

journal_title：World journal of gastroenterology

authors： Jia ZF,Wang LZ,Cao XY,Wang C,Cao DH,Wu X,You LL,Jin MS,Wang YP,Zhou BS,Jiang J

更新日期：2016-02-21 00:00:00

abstract：:Hepatitis C virus (HCV) infection disrupts the normal metabolism processes, but is also influenced by several of the host's metabolic factors. An obvious and significantly detrimental pathophysiological feature of HCV infection is insulin resistance in hepatic and peripheral tissues. Substantial research efforts have ...

journal_title：World journal of gastroenterology

authors： Kawaguchi Y,Mizuta T

更新日期：2014-03-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common and highly fatal malignancies worldwide. Chronic infection with hepatitis B virus (HBV) is a major cause of HCC. High HBV replication rate and related non-resolving inflammation are the major risk factors of HCC occurrence and postoperative recurrence. Early pro...

journal_title：World journal of gastroenterology

authors： Du Y,Han X,Ding YB,Yin JH,Cao GW

更新日期：2016-08-07 00:00:00

abstract：:Inflammatory bowel disease (IBD) is associated with increased risk of colorectal cancer (CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the h...

journal_title：World journal of gastroenterology

authors： Althumairi AA,Lazarev MG,Gearhart SL

更新日期：2016-01-21 00:00:00

abstract：AIM:To investigate the relationship between Helicobacter pylori (H. pylori) and mucin expression in gastric mucosa. METHODS:English Medical literature searches were conducted for gastric mucin expression in H. pylori infected people vs uninfected people. Searches were performed up to December 31(th) 2014, using MEDLIN...

journal_title：World journal of gastroenterology

authors： Niv Y

更新日期：2015-08-21 00:00:00

abstract：:Gastroduodenal disease (GDD) was initially thought to be uncommon in Africa. Amongst others, lack of access to optimal health infrastructure and suspicion of conventional medicine resulted in the reported prevalence of GDD being significantly lower than that in other areas of the world. Following the increasing availa...

journal_title：World journal of gastroenterology

authors： Archampong TN,Asmah RH,Richards CJ,Martin VJ,Bayliss CD,Botão E,David L,Beleza S,Carrilho C

更新日期：2019-07-14 00:00:00

abstract：:Cystic dystrophy of the duodenal wall is a rare condition characterized by the development of cysts in heterotopic pancreatic tissue localized in the duodenal wall. A 38-year-old man was admitted to the hospital for abdominal pain and vomiting after food intake. The diagnosis of acute pancreatitis was initially suspec...

journal_title：World journal of gastroenterology

authors： Jovanovic I,Knezevic S,Micev M,Krstic M

更新日期：2004-09-01 00:00:00

abstract：AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP). METHODS:We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery...

journal_title：World journal of gastroenterology

authors： Katsinelos P,Kountouras J,Chatzimavroudis G,Zavos C,Pilpilidis I,Fasoulas K,Paroutoglou G

更新日期：2009-12-28 00:00:00

abstract：:Interferon (IFN) therapy is the only treatment strategy for hepatitis C virus (HCV) infection after liver transplantation (LT), but prophylactic and treatable IFN therapy after LT has been shown to be insufficient due to the adverse effects of IFN and rivabirin. In this paper, we describe the disappearance of HCV afte...

journal_title：World journal of gastroenterology

authors： Ichikawa T,Nakao K,Hamasaki K,Honda T,Shibata H,Akahoshi M,Eguchi S,Takatsuki M,Kanematsu T,Eguchi K

更新日期：2007-08-14 00:00:00