Acute abdomen: rare and unusual presentation of right colic xanthogranulomatosis.

Abstract:

:Xanthogranulomatous inflammation (XGI) is a disease of unknown origin, most frequently described in the kidney and gallbladder; its localization in the colorectal tract is extremely rare. The extension of the typical inflammatory process to the surrounding tissues may lead to misdiagnosis as cancer. We report the case of a 56-year-old woman presenting to the Emergency Department with pain, increased levels of α1 and α2 proteins and C-reactive protein (17.5 mg/dL; normal value 0-0.5), and a palpable mass, localized in the right lower quadrant of the abdomen. A computed tomography scan showed a large right cecal mass with necrotic areas, local inflammation of retroperitoneal fat, and enlargement of local lymph nodes. Because of the high suspicion of colic abscess as well as malignancy and worsening of the clinical condition, the patient underwent right colectomy after 4 d of antibiotic treatment. Pathology revealed xanthogranulomatous inflammation involving the ileocecal valve. We review the reports of large bowel tract XGI in the international literature.

journal_name

World J Gastroenterol

authors

Addario Chieco P,Antolino L,Giaccaglia V,Centanini F,Cunsolo GV,Sparagna A,Uccini S,Ziparo V

doi

10.3748/wjg.v20.i26.8717

subject

Has Abstract

pub_date

2014-07-14 00:00:00

pages

8717-21

issue

26

eissn

1007-9327

issn

2219-2840

journal_volume

20

pub_type

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