A critical role of gastric mucosal ascorbic acid in the progression of acute gastric mucosal lesions induced by compound 48/80 in rats.

abstract：AIM:To investigate markers for high-grade dysplasia for the optimal timing of liver transplantation in patients with primary sclerosing cholangitis (PSC). METHODS:Earlier data support a dysplasia-carcinoma sequence, even low- to high-grade dysplasia, in PSC-associated cholangiocarcinoma (CCA). Surveillance using endos...

journal_title：World journal of gastroenterology

authors： Boyd S,Vannas M,Jokelainen K,Isoniemi H,Mäkisalo H,Färkkilä MA,Arola J

更新日期：2017-09-07 00:00:00

abstract：AIM:To evaluate the outcome of chronic hepatitis B (CHB) in children with or without malignancies. METHODS:Twenty four children (15 boys and 9 girls) with malignancies, followed up by the pediatric gastroenterology outpatient clinic for CHB between January 2000 and December 2013, were enrolled in the study (Group 1). ...

journal_title：World journal of gastroenterology

authors： Usta M,Urgancı N,Yıldırmak ZY,Dogan Vural S

更新日期：2015-02-21 00:00:00

abstract：AIM:To investigate the role of 64-slice computed tomography (CT) in portal vein cavernous transformation to determine surgical strategy. METHODS:The site of lesions and extent of collateral circulation in 12 pediatric cases of cavernous transformation of the portal vein with surgical treatment were analyzed. RESULTS:...

journal_title：World journal of gastroenterology

authors： Zhang MM,Pu CL,Li YC,Guo CB

更新日期：2011-10-14 00:00:00

abstract：AIM:To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in rats. METHODS:Giving a fructose-enriched diet (FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats (150-200 ...

journal_title：World journal of gastroenterology

authors： Abd El-Haleim EA,Bahgat AK,Saleh S

更新日期：2016-03-14 00:00:00

abstract：AIM:To determine whether oral glutathione (GSH) administration can alleviate the effects of fasting-induced intestinal atrophy in the small intestinal mucosa. METHODS:Rats were divided into eight groups. One group was fed ad libitum, another was fed ad libitum and received oral GSH, and six groups were administrated s...

journal_title：World journal of gastroenterology

authors： Uchida H,Nakajima Y,Ohtake K,Ito J,Morita M,Kamimura A,Kobayashi J

更新日期：2017-09-28 00:00:00

abstract：:The efficacy of triple therapy for Helicobacter pylori infection has dramatically declined over the last decade, largely related to increasing clarithromycin resistance rates. From a microbiological standpoint, bismuth quadruple therapy is the ideal replacement since it combines drugs for which resistance does not imp...

journal_title：World journal of gastroenterology

authors： Molina-Infante J,Gisbert JP

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the regulatory effect of electroacupuncture (EA) at Zusanli (ST36) on tumor necrosis factor-alpha (TNF-alpha) in rats with ulcerative colitis (UC), and further elucidate the therapeutic mechanism of EA on UC. METHODS:Thirty-two male Sprague-Dawley (SD) rats were randomly divided into four groups (n=...

journal_title：World journal of gastroenterology

authors： Tian L,Huang YX,Tian M,Gao W,Chang Q

更新日期：2003-05-01 00:00:00

abstract：:A primary clear cell adenocarcinoma of the colon is a rare oncologic entity. We herein report a case of such a tumor of the sigmoid colon in a 71-year-old woman who was successfully treated by an endoscopic polypectomy in our hospital. We also reviewed the published reports regarding cases of primary clear cell tumors...

journal_title：World journal of gastroenterology

authors： Soga K,Konishi H,Tatsumi N,Konishi C,Nakano K,Wakabayashi N,Mitsufuji S,Kataoka K,Okanoue T,Mukaisho K,Hattori T

更新日期：2008-02-21 00:00:00

abstract：:As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When con...

journal_title：World journal of gastroenterology

authors： Tenner S

更新日期：2014-11-28 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a major cause of cancer-related death, with a 5-year overall survival rate being below 5%. The main causes of poor prognosis in pancreatic cancer include easy metastasis, high recurrence rate, and robust drug resistance. Gemcitabine is a first-line drug for patients with unresectable pan...

journal_title：World journal of gastroenterology

authors： Wei L,Wen JY,Chen J,Ma XK,Wu DH,Chen ZH,Huang JL

更新日期：2019-10-07 00:00:00

abstract：:Neurofibromas of the large bowel are very rare and usually are part of the colonic involvement in neurofibromatosis type 1 (Nf1, von Recklinghausen's disease). Solitary neurofibromas of the colon are extremely rare. We describe a case of an isolated neurofibroma that was found in the large bowel of a patient who suffe...

journal_title：World journal of gastroenterology

authors： Panteris V,Vassilakaki T,Vaitsis N,Elemenoglou I,Mylonakou I,Karamanolis DG

更新日期：2005-09-21 00:00:00

abstract：AIM:To investigate the possible clinical application value of second harmonic imaging under low acoustic pressure. METHODS:Six New Zealand rabbits, averaging 2.7+/-0.4 kg, were selected and operated upon to construct hepatic VX2 tumor carrier model. Hepatic VX2 tumors were imaged with B mode Ultrasonography (US), and ...

journal_title：World journal of gastroenterology

authors： Du WH,Yang WX,Wang X,Xiong XQ,Zhou Y,Li T

更新日期：2003-08-01 00:00:00

abstract：AIM:To clarify the pathogenesis of gastroesophageal reflux disease symptoms in non-erosive reflux disease (NERD) patients. METHODS:Thirty-five NERD patients with persistent symptoms, despite taking rabeprazole 10 mg twice daily for at least 8 wk, were included in this study. All patients underwent 24 h combined impeda...

journal_title：World journal of gastroenterology

authors： Nakagawa K,Koike T,Iijima K,Saito M,Kikuchi H,Hatta W,Ara N,Uno K,Asano N,Shimosegawa T

更新日期：2015-12-21 00:00:00

abstract：AIM:To assess the role of IgM and IgG immunohistochemistry (IHC) in the evaluation of autoimmune liver conditions--autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC). METHODS:Forty one biopsies from untreated patients diagnosed with autoimmune liver disease (AIH, n = ...

journal_title：World journal of gastroenterology

authors： Moreira RK,Revetta F,Koehler E,Washington MK

更新日期：2010-01-28 00:00:00

abstract：AIM:To identify the prevalence of hepatitis B e antigen (HBeAg) and to assess the association of hepatitis B virus (HBV) core promoter mutations and viral load in Indonesian patients. METHODS:Sixty-four patients with chronic hepatitis, 65 with liver cirrhosis and 50 with hepatocellular carcinoma were included in this ...

journal_title：World journal of gastroenterology

authors： Utama A,Siburian MD,Purwantomo S,Intan MD,Kurniasih TS,Gani RA,Achwan WA,Arnelis,Lelosutan SA,Lukito B,Harmono T,Zubir N,Julius,Soemohardjo S,Lesmana LA,Sulaiman A,Tai S

更新日期：2011-02-14 00:00:00

abstract：AIM:To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS:Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean ...

journal_title：World journal of gastroenterology

authors： Hwang J,Kim JS,Kim AY,Lim JS,Kim SH,Kim MJ,Kim MS,Song KD,Woo JY

更新日期：2017-07-07 00:00:00

abstract：AIM:To develop a highly efficacious method for preparation of soluble SARS S-protein using adenovirus vector to meet the requirement for S-protein investigation. METHODS:The human adenovirus vector was used to express the soluble S-protein (corresponding to 1 approximately 1190 amino acids) fused with Myc/His tag usin...

journal_title：World journal of gastroenterology

authors： Zhong F,Zhong ZY,Liang S,Li XJ

更新日期：2006-03-07 00:00:00

abstract：:Despite major improvements concerning its diagnosis and treatment, pancreatic ductal adenocarcinoma (PDAC) remains an aggressive disease with an extremely poor prognosis. Pathology, as interface discipline between basic and clinical medicine, has substantially contributed to the recent developments and has laid the ba...

journal_title：World journal of gastroenterology

authors： Esposito I,Konukiewitz B,Schlitter AM,Klöppel G

更新日期：2014-10-14 00:00:00

abstract：AIM:To investigate the effects of exogenously mutated p27(kipl) (p27) on proliferation and apoptosis of human cholangiocarcinoma cell line, QBC(939)in vivo. METHODS:Adenviral vectors were used to transfect mutated p27 cDNA into human QBC(939)cell line. Expression of p27 was detected by RT-PCR. Western blot. Cell growt...

journal_title：World journal of gastroenterology

authors： Luo J,Chen YJ,Wang WY,Zou SQ

更新日期：2008-09-14 00:00:00

abstract：AIM:To investigate the interstitial cells of Cajal (ICC) number using a new rat model. METHODS:Sprague-Dawley rats were assigned to two groups. The first group received gavage with Campylobacter jejuni (C. jejuni) 81-176. The second group was gavaged with placebo. Three months after clearance of Campylobacter from the...

journal_title：World journal of gastroenterology

authors： Jee SR,Morales W,Low K,Chang C,Zhu A,Pokkunuri V,Chatterjee S,Soffer E,Conklin JL,Pimentel M

更新日期：2010-08-07 00:00:00

abstract：:Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. The identification of colonic polyps can reduce CRC mortality through earlier diagnosis of cancers and the removal of polyps: the precursor lesion of CRC. Following the finding and removal of colonic polyps at an initial colonoscopy, some p...

journal_title：World journal of gastroenterology

authors： Bonnington SN,Rutter MD

更新日期：2016-02-14 00:00:00

abstract：:The gastrointestinal innate and adaptive immune system continuously faces the challenge of potent stimuli from the commensal microflora and food constituents. These local immune responses require a tight control, the outcome of which is in most cases the induction of tolerance. Local T cell immunity is an important co...

journal_title：World journal of gastroenterology

authors： Niess JH

更新日期：2008-09-07 00:00:00

abstract：AIM:To investigate the tumor-suppressive effect of the phosphatase and tensin homologue deleted from chromosome (PTEN) in human gastric cancer cells that were wild type for PTEN. METHODS:Adenoviruses expressing PTEN or luciferase as a control were introduced into gastric cancer cells. The effect of exogenous PTEN gene...

journal_title：World journal of gastroenterology

authors： Hang Y,Zheng YC,Cao Y,Li QS,Sui YJ

更新日期：2005-04-21 00:00:00

abstract：:Although recent diagnostic and therapeutic advances have substantially improved the survival of patients with gastric cancer (GC), the overall prognosis is still poor. Surgery is the only curative treatment and should be performed in experienced centers. Due to high relapse following surgery, complementary and systemi...

journal_title：World journal of gastroenterology

authors： Cravo M,Fidalgo C,Garrido R,Rodrigues T,Luz G,Palmela C,Santos M,Lopes F,Maio R

更新日期：2015-11-07 00:00:00

abstract：:Helicobacter pylori (H. pylori) colonizes the stomach of humans and causes chronic infection. The majority of bacteria live in the mucus layer overlying the gastric epithelial cells and only a small proportion of bacteria are found interacting with the epithelial cells. The bacteria living in the gastric mucus may act...

journal_title：World journal of gastroenterology

authors： Dunne C,Dolan B,Clyne M

更新日期：2014-05-21 00:00:00

abstract：:Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas (UCOGCP) is an unusual pancreatic neoplasm that represents < 1% of all pancreatic malignancies. Moreover, the giant cells of UCOGCP morphologically resemble the benign giant cells of bone tumors. Due to the rarity of this tumor type, the histo...

journal_title：World journal of gastroenterology

authors： Gao HQ,Yang YM,Zhuang Y,Liu P

更新日期：2015-01-14 00:00:00

abstract：:Increased numbers of mucosa-associated Escherichia coli are observed in both of the major inflammatory bowel diseases, Crohn d' disease (CD) and ulcerative colitis (UC). A potential pathophysiological link between the presence of pathogenic invasive bacteria and genetic host susceptibility of patients with ileal CD is...

journal_title：World journal of gastroenterology

authors： Barnich N,Darfeuille-Michaud A

更新日期：2007-11-14 00:00:00

abstract：AIM:To determine the incidence of human epidermal growth factor receptor 2 (HER2) over expression in oesophageal cancers. METHODS:A retrospective study, of one hundred consecutive cases of endoscopic histological samples of oesophageal cancers from a single British cancer network were included. Cancer cases were diagn...

journal_title：World journal of gastroenterology

authors： Al-Momani H,Barnes R,El-Hadi A,Shah R,Lewis WG,Edwards P

更新日期：2012-11-28 00:00:00

abstract：AIM:To investigate the inhibitory effect and possible mechanism of action of schisandrin B in SC-B on gastric cancer cells in vitro. METHODS:SC-B consisted of schisandrin B, aloe-emodin, and Astragalus polysaccharides. Exponentially growing human gastric cancer SGC-7901 cells were divided into six treatment groups: (1...

journal_title：World journal of gastroenterology

authors： Liu XN,Zhang CY,Jin XD,Li YZ,Zheng XZ,Li L

更新日期：2007-12-28 00:00:00

abstract：AIM:To investigate the effect of Danzhijiangtang capsule (DJC) on monocyte chemoattractant protein-1 (MCP-1) mRNA expression in newly diagnosed type 2 diabetes mellitus (T2DM) subclinical vascular lesions. METHODS:Sixty-two patients with newly diagnosed T2DM subclinical vascular lesions were randomly divided into a co...

journal_title：World journal of gastroenterology

authors： Fang ZH,Liu Y,Bao TT,Ni YQ,Liu J,Shi GB,Wu JP,Yang JP,Zhang H

更新日期：2013-05-21 00:00:00