Assessment of hepatic VX2 tumors of rabbits with second harmonic imaging under high and low acoustic pressures.

Abstract:

AIM:To investigate the possible clinical application value of second harmonic imaging under low acoustic pressure. METHODS:Six New Zealand rabbits, averaging 2.7+/-0.4 kg, were selected and operated upon to construct hepatic VX2 tumor carrier model. Hepatic VX2 tumors were imaged with B mode Ultrasonography (US), and second harmonic imaging (SHI) under high mechanic index (1.6) and low mechanic index (0.1). Echo agent was intravenously injected through ear vein at a dose of 0.01 mL/kg under B mode US and high MI SHI, and 0.05 mL/kg under low MI SHI, and then the venous channel was cleaned with sterilized saline. All the images were recorded by magnetic optics (MO), and they were analyzed further by at least two independent experienced sonographers. RESULTS:Totally 6 hypoechoic and 3 hyperechoic lesions were found in the six carrier rabbits with a mean size about 2.1+/-0.4 under B mode ultrasound, they were oval or round in shape with a clear outline or a hypoechoic halo at the margin of the lesions. Contrast agent could not change the echogenicity of the lesions under B mode US and SHI under high acoustic pressure. However, it could greatly increase the real time visualization sensitivity of the lesions with SHI under low acoustic pressure. CONCLUSION:Our results suggest that contrast enhanced SHI with low MI and a bubble non-destructive method would be much more helpful than conventional SHI in our future clinical applications.

journal_name

World J Gastroenterol

authors

Du WH,Yang WX,Wang X,Xiong XQ,Zhou Y,Li T

doi

10.3748/wjg.v9.i8.1679

keywords:

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

1679-82

issue

8

eissn

1007-9327

issn

2219-2840

journal_volume

9

pub_type

杂志文章
  • Malignant solitary fibrous tumor involving the liver.

    abstract::Solitary fibrous tumors are predominantly benign and are most commonly found in the thoracic cavity and pleura; while reports exist in the literature of malignant solitary fibrous tumors and those located in extrathoracic organs, these cases are considered extremely rare. Herein, a case is reported of a malignant soli...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i21.3354

    authors: Jakob M,Schneider M,Hoeller I,Laffer U,Kaderli R

    更新日期:2013-06-07 00:00:00

  • Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting.

    abstract:AIM:To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS:We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding t...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i48.7779

    authors: Enns RA,Gagnon YM,Barkun AN,Armstrong D,Gregor JC,Fedorak RN,RUGBE Investigators Group.

    更新日期:2006-12-28 00:00:00

  • Non-invasive biomarkers for monitoring the fibrogenic process in liver: a short survey.

    abstract::The clinical course of chronic liver diseases is significantly dependent on the progression rate and the extent of fibrosis, i.e. the non-structured replacement of necrotic parenchyma by extracellular matrix. Fibrogenesis, i.e. the development of fibrosis can be regarded as an unlimited wound healing process, which is...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.15.2433

    authors: Gressner AM,Gao CF,Gressner OA

    更新日期:2009-05-28 00:00:00

  • Anterior vs conventional approach hepatectomy for large liver cancer: a meta-analysis.

    abstract:AIM:To evaluate the clinical outcomes and safety of anterior- and conventional-approach hepatectomy for patients with large liver tumors. METHODS:PubMed, EMBASE, Google Scholar and the Cochrane Library databases were searched for randomized controlled trials (RCTs) and controlled clinical trials comparing anterior-app...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.v20.i45.17235

    authors: Li L,Wang HQ,Wang Q,Yang J,Yang JY

    更新日期:2014-12-07 00:00:00

  • Endoscopic treatment of Barrett's esophagus: From metaplasia to intramucosal carcinoma.

    abstract::The annual incidence of adenocarcinoma arising from Barrett's esophagus (BE) is approximately 0.5%. Through a process of gradual transformation from low-grade dysplasia to high-grade dysplasia (HGD), adenocarcinoma can develop in the setting of BE. The clinical importance of appropriate identification and treatment of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i30.3780

    authors: Chennat J,Waxman I

    更新日期:2010-08-14 00:00:00

  • Endoscopic submucosal dissection for early esophageal neoplasms using the stag beetle knife.

    abstract:AIM:To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device. METHODS:Seventy consecutive patients with 96 early esophageal neoplasms, who underwent ESD using a SB knife at Kure Medical Center and Chugoku Cancer Center, Japan, betwee...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i15.1632

    authors: Kuwai T,Yamaguchi T,Imagawa H,Miura R,Sumida Y,Takasago T,Miyasako Y,Nishimura T,Iio S,Yamaguchi A,Kouno H,Kohno H,Ishaq S

    更新日期:2018-04-21 00:00:00

  • Alcoholism and liver disease in Mexico: genetic and environmental factors.

    abstract::Alcoholism and cirrhosis, which are two of the most serious health problems worldwide, have a broad spectrum of clinical outcomes. Both diseases are influenced by genetic susceptibility and cultural traits that differ globally but are specific for each population. In contrast to other regions around the world, Mexican...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i44.7972

    authors: Roman S,Zepeda-Carrillo EA,Moreno-Luna LE,Panduro A

    更新日期:2013-11-28 00:00:00

  • Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy.

    abstract:AIM:To examine the characteristics of colonic polyps, where it is difficult to distinguish adenomatous polyps from hyperplastic polyps, with the aid of acetic acid chromoendoscopy. METHODS:Acetic acid spray was applied to colonic polyps smaller than 10 mm before complete excision. Endoscopic images were taken before a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.1903

    authors: Kim JH,Lee SY,Kim BK,Choe WH,Kwon SY,Sung IK,Park HS,Jin CJ

    更新日期:2008-03-28 00:00:00

  • Resolution of chronic hepatitis C following parasitosis.

    abstract::An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i31.4268

    authors: Byrnes V,Chopra S,Koziel MJ

    更新日期:2007-08-21 00:00:00

  • Risk factors and outcome of bacterial infections in cirrhosis.

    abstract::Viable and non-viable pathological bacterial translocation promote a self-perpetuating circle of dysfunctional immune activation and systemic inflammation facilitating infections and organ failure in advanced cirrhosis. Bacterial infections and sepsis are now recognized as a distinct stage in the natural progression o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i10.2542

    authors: Bruns T,Zimmermann HW,Stallmach A

    更新日期:2014-03-14 00:00:00

  • Pancreatic necrosis and severity are independent risk factors for pancreatic endocrine insufficiency after acute pancreatitis: A long-term follow-up study.

    abstract:BACKGROUND:Pancreatic endocrine insufficiency after acute pancreatitis (AP) has drawn increasing attention in recent years. AIM:To assess the impact of risk factors on the development of pancreatic endocrine insufficiency after AP. METHODS:This retrospective observational long-term follow-up study was conducted in a ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i23.3260

    authors: Yu BJ,Li NS,He WH,He C,Wan JH,Zhu Y,Lu NH

    更新日期:2020-06-21 00:00:00

  • Drug induced acute pancreatitis: does it exist?

    abstract::As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When con...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i44.16529

    authors: Tenner S

    更新日期:2014-11-28 00:00:00

  • Endoscopic occlusion with silicone spigots for the closure of refractory esophago-bronchiole fistula after esophagectomy.

    abstract::A 65-year-old man with cT1bN0M0 stage I middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiotherapy and chemotherapy in a clinical trial. Anastomotic leakage occurred, but it spontaneously improved...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i28.5253

    authors: Uesato M,Kono T,Akutsu Y,Murakami K,Kagaya A,Muto Y,Nakano A,Aikawa M,Tamachi T,Amagai H,Arasawa T,Muto Y,Matsubara H

    更新日期:2017-07-28 00:00:00

  • Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis.

    abstract:AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i47.5351

    authors: Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

    更新日期:2018-12-21 00:00:00

  • Early prediction of major depression in chronic hepatitis C patients during peg-interferon alpha-2b treatment by assessment of vegetative-depressive symptoms after four weeks.

    abstract:AIM:To study the predictive value of the vegetative-depressive symptoms of the Zung Depression Rating Scale for the occurrence of depression during treatment with peg-interferon alpha-2b of chronic hepatitis C (CHC) patients. METHODS:The predictive value of vegetative-depressive symptoms at 4 wk of treatment for the o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3748/wjg.v13.i43.5736

    authors: Robaeys G,De Bie J,Wichers MC,Bruckers L,Nevens F,Michielsen P,Van Ranst M,Buntinx F

    更新日期:2007-11-21 00:00:00

  • Sex- and gender-specific disparities in colorectal cancer risk.

    abstract::Colorectal cancer is one of the most common causes of cancer morbidity both in men and in women. However, females over 65 years old show higher mortality and lower 5-year survival rate of colorectal cancer compared to their age-matched male counterparts. The objective of this review is to suggest gender-based innovati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i17.5167

    authors: Kim SE,Paik HY,Yoon H,Lee JE,Kim N,Sung MK

    更新日期:2015-05-07 00:00:00

  • Higher parity associated with higher risk of death from gastric cancer.

    abstract:AIM:To examine the association between parity and gastric cancer (the cases are almost all premenopausal women) risk in a cohort of young parous women. METHODS:The study cohort consisted of all women with a record of a first and singleton childbirth in the Birth Register between 1978 and 1987. We tracked each woman fr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i6.784

    authors: Chang CC,Chen CC,Chiu HF,Yang CY

    更新日期:2011-02-14 00:00:00

  • Practical approaches to effective management of intestinal radiation injury: benefit of resectional surgery.

    abstract:AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS:During a 7-year period we operated on 17 cases (5 male, 12 female) admitted to our surgical department with intestinal radiation injury (IRI). They were...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i35.4013

    authors: Perrakis N,Athanassiou E,Vamvakopoulou D,Kyriazi M,Kappos H,Vamvakopoulos NC,Nomikos I

    更新日期:2011-09-21 00:00:00

  • Ste20-related proline/alanine-rich kinase: a novel regulator of intestinal inflammation.

    abstract::Recently, inflammatory bowel disease (IBD) has been the subject of considerable research, with increasing attention being paid to the loss of intestinal epithelial cell barrier function as a mechanism of pathogenesis. Ste20-related proline/alanine-rich kinase (SPAK) is involved in regulating barrier function. SPAK is ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.14.6115

    authors: Yan Y,Merlin D

    更新日期:2008-10-28 00:00:00

  • Molecular targeted therapy for hepatocellular carcinoma: current and future.

    abstract::Hepatocellular carcinoma (HCC) is one of the most frequent tumors worldwide. The majority of HCC cases occur in patients with chronic liver disease. Despite regular surveillance to detect small HCC in these patients, HCC is often diagnosed at an advanced stage. Because HCC is highly resistant to conventional systemic ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i37.6144

    authors: Shin JW,Chung YH

    更新日期:2013-10-07 00:00:00

  • "Rescue" regimens after Helicobacter pylori treatment failure.

    abstract::Helicobacter pylori (H pylori) infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After more than 20 years of experience in H pylori treatment, in my opinion, the ideal regimen to treat this infection is still to be found. Currently, apart from having to know first-line eradica...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.14.5385

    authors: Gisbert JP

    更新日期:2008-09-21 00:00:00

  • Treatment of gastric outlet and duodenal obstructions with uncovered expandable metal stents.

    abstract:AIM:To investigate and evaluate the technical feasibility and clinical effectiveness of fluoroscopically guided peroral uncovered expandable metal stent placement to treat gastric outlet and duodenal obstructions. METHODS:Fifteen consecutive patients underwent peroral placement of Wallstent(TM) Enteral Endoprosthesis ...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v13.i40.5376

    authors: Huang Q,Dai DK,Qian XJ,Zhai RY

    更新日期:2007-10-28 00:00:00

  • The blind men 'see' the elephant-the many faces of fatty liver disease.

    abstract::Nonalcoholic fatty liver disease (NAFLD) is a group of diseases with excess fat in liver in the absence of a poorly defined limit of alcohol consumption. Most common variety, a universal public health problem, is associated with insulin resistance caused by a host of genetic and epigenetic defects modulated by life st...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.14.831

    authors: Sanal MG

    更新日期:2008-02-14 00:00:00

  • Clinical outcomes and predictive factors in oral corticosteroid-refractory active ulcerative colitis.

    abstract:AIM:To evaluate the clinical outcomes and prognostic factors after intravenous corticosteroids following oral corticosteroid failure in active ulcerative colitis patients. METHODS:Consecutive patients with moderate to severe ulcerative colitis who had been treated with a course of intravenous corticosteroids after ora...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i2.265

    authors: Jeon HH,Lee HJ,Jang HW,Yoon JY,Jung YS,Park SJ,Hong SP,Kim TI,Kim WH,Cheon JH

    更新日期:2013-01-14 00:00:00

  • H pylori and host interactions that influence pathogenesis.

    abstract::H. pylori is probably the most prevalent human pathogen worldwide. Since it was initially suggested in 1983 by Marshall and Warren to be implicated in gastritis and peptic ulcer disease, H. pylori has also been implicated in gastric carcinoma and was classified as a class I carcinogen. In the last two decades, a notew...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v12.i35.5599

    authors: Beswick EJ,Suarez G,Reyes VE

    更新日期:2006-09-21 00:00:00

  • Retrospective analysis of extra-gastrointestinal stromal tumors.

    abstract:AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors (EGISTs) in South Korea. METHODS:A total of 51 patients with an EGIST were identified. The clinicopathologic features, including sex, age, location, tumor size, histology, mitotic rate, immunohistochemical features...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i6.1845

    authors: Yi JH,Park BB,Kang JH,Hwang IG,Shin DB,Sym SJ,Ahn HK,Lee SI,Lim DH,Park KW,Won YW,Lim SH,Park SH

    更新日期:2015-02-14 00:00:00

  • Preoperative gamma-glutamyltransferase to lymphocyte ratio predicts long-term outcomes in intrahepatic cholangiocarcinoma patients following hepatic resection.

    abstract:BACKGROUND:Intrahepatic cholangiocarcinoma (ICC) is a heterogeneous hepatobiliary cancer with limited treatment options. A number of studies have illuminated the relationship between inflammation-based prognostic scores and outcomes in patients with ICC. However, the use of reliable and personalized prognostic algorith...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i13.1501

    authors: Wang JJ,Li H,Li JX,Xu L,Wu H,Zeng Y

    更新日期:2020-04-07 00:00:00

  • Interaction between hepatitis C virus and metabolic factors.

    abstract::Hepatitis C virus (HCV) infection disrupts the normal metabolism processes, but is also influenced by several of the host's metabolic factors. An obvious and significantly detrimental pathophysiological feature of HCV infection is insulin resistance in hepatic and peripheral tissues. Substantial research efforts have ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i11.2888

    authors: Kawaguchi Y,Mizuta T

    更新日期:2014-03-21 00:00:00

  • Treatment and survival in a population-based sample of patients diagnosed with gastroesophageal adenocarcinoma.

    abstract:AIM:To examine the extent of use of specific therapies in clinical practice, and their relationship to therapies validated in clinical trials. METHODS:The US National Cancer Institutes' Patterns of Care study was used to examine therapies and survival of patients diagnosed in 2001 with histologically-confirmed gastroe...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.3165

    authors: Cronin-Fenton DP,Mooney MM,Clegg LX,Harlan LC

    更新日期:2008-05-28 00:00:00

  • Autoantibodies in primary sclerosing cholangitis.

    abstract::The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as to whether PSC should be denominated an autoimmune disease. A large number of autoantibodies have been detected in PSC patients, but the specificity of these antibodies is generally low, and the frequencies vary largely betwee...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.14.3781

    authors: Hov JR,Boberg KM,Karlsen TH

    更新日期:2008-06-28 00:00:00