Alcoholism and liver disease in Mexico: genetic and environmental factors.

abstract：:Inflammatory bowel disease is an important cause of gastrointestinal pathology in children and adolescents. The incidence of pediatric inflammatory bowel disease is increasing; therefore, it is important for the clinician to be aware of the presentation of this disease in the pediatric population. Laboratory tests, ra...

journal_title：World journal of gastroenterology

authors： Diefenbach KA,Breuer CK

更新日期：2006-05-28 00:00:00

abstract：:Management of hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT) is complex and requires an understanding of multiple therapeutic options. PVT is present in 10%-40% of HCC at the time of diagnosis, and is an adverse prognostic factor. Management options are limited, as transplantation is generally contra...

journal_title：World journal of gastroenterology

authors： Quirk M,Kim YH,Saab S,Lee EW

更新日期：2015-03-28 00:00:00

abstract：AIM:to determine the effect of free serotonin concentrations in plasma on development of esophageal and gastric fundal varices. METHODS:this prospective study included 33 patients with liver cirrhosis and 24 healthy controls. Ultrasonography and measurement of serotonin concentration in plasma were carried out in both...

journal_title：World journal of gastroenterology

authors： Rudić JS,Culafić DM,Mirković DS,Ješić RS,Krstić MN

更新日期：2010-12-28 00:00:00

abstract：AIM:To examine the association between parity and gastric cancer (the cases are almost all premenopausal women) risk in a cohort of young parous women. METHODS:The study cohort consisted of all women with a record of a first and singleton childbirth in the Birth Register between 1978 and 1987. We tracked each woman fr...

journal_title：World journal of gastroenterology

authors： Chang CC,Chen CC,Chiu HF,Yang CY

更新日期：2011-02-14 00:00:00

abstract：AIM:To investigate the molecular mechanism for regulation of cholesterol metabolism by hepatitis C virus (HCV) core protein in HepG2 cells. METHODS:HCV genotype 1b core protein was cloned and expressed in HepG2 cells. The cholesterol content was determined after transfection. The expression of sterol regulatory elemen...

journal_title：World journal of gastroenterology

authors： Li M,Wang Q,Liu SA,Zhang JQ,Ju W,Quan M,Feng SH,Dong JL,Gao P,Cheng J

更新日期：2015-04-21 00:00:00

abstract：AIM:To investigate the effect of transfected survivin antisense oligonucleotide (ASODN) on proliferation and apoptosis of gastric cancer cells. METHODS:The authors designed ASODNs targeting different regions of survivin mRNA, including surviving ASODN1, ASODN2 and ASODN3. ASODNs were transfected into gastric cancer ce...

journal_title：World journal of gastroenterology

authors： Yang JH,Zhang YC,Qian HQ

更新日期：2004-04-15 00:00:00

abstract：AIM:To study the pattern of cancer incidence and determine the incidence rates in Eastern Libya (for the first time in a decade). METHODS:A hospital-based registry of cancer patients was formed using records from the primary oncology center in eastern Libya - focusing on those diagnosed in the year 2012. RESULTS:The ...

journal_title：World journal of gastroenterology

authors： Bodalal Z,Azzuz R,Bendardaf R

更新日期：2014-05-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) is a prevalent, worldwide, chronic infection. Choice of treatment can be modified according to antibiotic-resistance rates of H. pylori. The ideal therapeutic regimen for H. pylori infection should achieve an eradication rate of ≥ 80%. In some countries, triple therapy with a proton-pum...

journal_title：World journal of gastroenterology

authors： Alahdab YO,Kalayci C

更新日期：2014-05-14 00:00:00

abstract：:Chronic intake of alcohol undoubtedly overwhelms the structural and functional capacity of the liver by initiating complex pathological events characterized by steatosis, steatohepatitis, hepatic fibrosis and cirrhosis. Subsequently, these initial pathological events are sustained and ushered into a more complex and p...

journal_title：World journal of gastroenterology

authors： Boye A,Zou YH,Yang Y

更新日期：2016-01-07 00:00:00

abstract：AIM:To evaluate when Helicobacter pylori (H. pylori) eradication therapy (ET) should be started in patients with peptic ulcer bleeding (PUB). METHODS:Clinical data concerning adults hospitalized with PUB were retrospectively collected and analyzed. Age, sex, type and stage of peptic ulcer, whether endoscopic therapy w...

journal_title：World journal of gastroenterology

authors： Yoon H,Lee DH,Jang ES,Kim J,Shin CM,Park YS,Hwang JH,Kim JW,Jeong SH,Kim N

更新日期：2015-02-28 00:00:00

abstract：:Colonic motility subserves large bowel functions, including absorption, storage, propulsion and defaecation. Colonic motor dysfunction remains the leading hypothesis to explain symptom generation in chronic constipation, a heterogeneous condition which is extremely prevalent in the general population, and has huge soc...

journal_title：World journal of gastroenterology

authors： Dinning PG,Benninga MA,Southwell BR,Scott SM

更新日期：2010-11-07 00:00:00

abstract：AIM:To construct a recombinant strain which highly expresses catalase of Helicobacter pylori (H. pylori) and assay the activity of H. pylori catalase. METHODS:The catalase DNA was amplified from H. pylori chromosomal DNA with PCR techniques and inserted into the prokaryotie expression vector pET-22b (+), and then was ...

journal_title：World journal of gastroenterology

authors： Bai Y,Zhang YL,Jin JF,Wang JD,Zhang ZS,Zhou DY

更新日期：2003-05-01 00:00:00

abstract：:Novel molecular targets are being discovered as we learn more about the aberrant processes underlying various cancers. Efforts to translate this knowledge are starting to impact on the care of patients with gastrointestinal cancers. The epidermal growth factor receptor (EGFR) pathway and angiogenesis have been targete...

journal_title：World journal of gastroenterology

authors： Ma WW,Hidalgo M

更新日期：2007-11-28 00:00:00

abstract：AIM:To evaluate the effect of gastrectomy on diabetes mellitus (DM) and hypertension (HTN) in non-obese gastric cancer patients. METHODS:A total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and ...

journal_title：World journal of gastroenterology

authors： Lee EK,Kim SY,Lee YJ,Kwak MH,Kim HJ,Choi IJ,Cho SJ,Kim YW,Lee JY,Kim CG,Yoon HM,Eom BW,Kong SY,Yoo MK,Park JH,Ryu KW

更新日期：2015-01-28 00:00:00

abstract：:Inflammatory bowel disease (IBD) is comprised of Crohn's disease and ulcerative colitis, both chronic inflammatory intestinal disorders of unknown etiology characterized by a waxing and waning clinical course. For many years, the drug therapy was limited to sulfasalazine and related aminosalicylates, corticosteroids a...

journal_title：World journal of gastroenterology

authors： Zenlea T,Peppercorn MA

更新日期：2014-03-28 00:00:00

abstract：:Intestinal lymphangiectasia, characterized by dilatation of intestinal lacteals, is rare. The major treatment for primary intestinal lymphangiectasia is dietary modification. Surgery to relieve symptoms and to clarify the etiology should be considered when medical treatment failed. This article reports a 49-year-old w...

journal_title：World journal of gastroenterology

authors： Chen CP,Chao Y,Li CP,Lo WC,Wu CW,Tsay SH,Lee RC,Chang FY

更新日期：2003-12-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis, includes inflammation and...

journal_title：World journal of gastroenterology

authors： Pacifico L,Nobili V,Anania C,Verdecchia P,Chiesa C

更新日期：2011-07-14 00:00:00

abstract：:Many of the drugs currently used in medical practice are racemates. The enantiomers of a racemic drug differ in pharmacodynamics and/or pharmacokinetics, thus in some cases it is preferable to develop pure enantiomers by racemic switch. In a recent study by Pai et al, dexrabeprazole [R(+)-rabeprazole] (10 mg) was foun...

journal_title：World journal of gastroenterology

authors： Zhou Q,Yan XF,Pan WS,Zeng S

更新日期：2008-04-28 00:00:00

abstract：AIM:To investigate the roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. METHODS:Human gastric cancer SGC-7901 cells were treated with VES at 5, 10, 20 mg x L(-1), succinic acid and vitamin E as vehicle control and condition media only as untreated (UT) con...

journal_title：World journal of gastroenterology

authors： Wu K,Li Y,Zhao Y,Shan YJ,Xia W,Yu WP,Zhao L

更新日期：2002-12-01 00:00:00

abstract：:Severe acute hepatitis of unknown etiology is difficult to treat and often progresses to subacute fulminant hepatitis or late-onset hepatic failure. A 45-year-old well-nourished, healthy man had progressive fatigue and his liver function tests showed severe liver dysfunction. The etiology of sever acute cholestatic he...

journal_title：World journal of gastroenterology

authors： Ohwada S,Kobayashi I,Harasawa N,Tsuda K,Inui Y

更新日期：2009-06-21 00:00:00

abstract：:The search for biomarkers that characterize specific aspects of inflammatory bowel disease (IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating ...

journal_title：World journal of gastroenterology

authors： Quetglas EG,Mujagic Z,Wigge S,Keszthelyi D,Wachten S,Masclee A,Reinisch W

更新日期：2015-11-28 00:00:00

abstract：BACKGROUND:Identifying predictors of therapeutic response is the cornerstone of personalized medicine. AIM:To identify predictors of long-term mucosal healing (MH) in patients with Crohn's disease (CD) treated with tumor necrosis factor α (TNF-α) inhibitors. METHODS:Prospective single center study. Consecutive patien...

journal_title：World journal of gastroenterology

authors： Alfaro I,Masamunt MC,Planell N,López-García A,Castro J,Gallego M,Barastegui R,Giner A,Vara A,Salas A,Ricart E,Panés J,Ordás I

更新日期：2019-04-14 00:00:00

abstract：AIM:To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. METHODS:High throughput screening using TaqMan® Array Human MicroRNA quantitative PCR was used to determine expression levels of 754 microRNAs in distal esophageal mu...

journal_title：World journal of gastroenterology

authors： Sreedharan L,Mayne GC,Watson DI,Bright T,Lord RV,Ansar A,Wang T,Kist J,Astill DS,Hussey DJ

更新日期：2017-08-14 00:00:00

abstract：:The diagnosis of herbal hepatotoxicity or herb induced liver injury (HILI) represents a particular clinical and regulatory challenge with major pitfalls for the causality evaluation. At the day HILI is suspected in a patient, physicians should start assessing the quality of the used herbal product, optimizing the clin...

journal_title：World journal of gastroenterology

authors： Teschke R,Frenzel C,Schulze J,Eickhoff A

更新日期：2013-05-21 00:00:00

abstract：AIM:To investigate anti-apoptotic effects of glycyrrhizic acid (GA) against fibrosis in carbon tetrachloride (CCl4)-induced liver injury and its contributing factors. METHODS:Liver fibrosis was induced by administration of CCl4 for 8 wk. Pathological changes in the liver of rats were examined by hematoxylin-eosin stai...

journal_title：World journal of gastroenterology

authors： Liang B,Guo XL,Jin J,Ma YC,Feng ZQ

更新日期：2015-05-07 00:00:00

abstract：:Dilatation of the colon and the rectum, which is not attributable to aganglionosis, is a rare finding and can be the result of intractable chronic constipation. We report a rare case of a 29-year-old male patient with impressive megacolon, in whom Hirschsprung's or Chagas disease was ruled out. In the present case, di...

journal_title：World journal of gastroenterology

authors： Mecklenburg I,Leibig M,Weber C,Schmidbauer S,Folwaczny C

更新日期：2005-12-28 00:00:00

abstract：:Cancer patients have unique problems associated with hepatitis C virus (HCV) infection and treatment not seen in the general population. HCV infection poses additional challenges and considerations for the management of cancer, and vice versa. HCV infection also can lead to the development of cancer, particularly hepa...

journal_title：World journal of gastroenterology

authors： Borchardt RA,Torres HA

更新日期：2014-03-21 00:00:00

abstract：AIM:To evaluate the feasibility of quantifying liver choline concentrations in both normal and apoptotic rabbit livers in vivo, using 1H magnetic resonance spectroscopy (1H-MRS). METHODS:1H-MRS was performed in 18 rabbits using a 1.5T GE MR system with an eight-channel head/neck receiving coil. Fifteen rabbits were in...

journal_title：World journal of gastroenterology

authors： Shen ZW,Cao Z,You KZ,Yang ZX,Xiao YY,Cheng XF,Chen YW,Wu RH

更新日期：2012-03-14 00:00:00

abstract：AIM:The significance of hepatitis C virus (HCV) serum titers has been examined in several clinical situations. There is much evidence that patients with a lower viral load have better response rates to anti-viral therapy compared to those with higher levels. Moreover, a direct association has been observed between seru...

journal_title：World journal of gastroenterology

authors： Anand BS,Velez M

更新日期：2004-08-15 00:00:00

abstract：:Coeliac disease (CD) is a complex condition resulting from an interplay between genetic and environmental factors. When diagnosing the condition, serological testing and genotyping are useful in excluding CD, although the gold standard of testing is currently histopathological examination of the small intestine. There...

journal_title：World journal of gastroenterology

authors： Charlesworth RP

更新日期：2020-01-07 00:00:00