Combined en bloc liver/pancreas transplantation in two different patients.

Abstract:

:Combined en bloc liver/pancreas transplantation (CLPT) was used primarily in the treatment of otherwise non-resectable upper abdominal malignancy. In fact, a more appropriate indication is in patients with liver disease and insulin-dependent diabetes mellitus (IDDM). Here, we report on two successful cases of CLPT at our hospital. One was a patient with non-resectable advanced liver cancer. The recipient survived for 23 mo and finally died of recurrent tumor. The other was a patient with severe biliary complication after orthotopic liver transplantation and preoperative IDDM. We performed CLPT with a modified surgical technique of preserving the native pancreas. He is currently liver-disease- and insulin-free more than 27 mo post-transplant. Based on our experience in two cases of abdominal cluster transplantation, we describe the technical details of CLPT and a modification of the surgical procedure.

journal_name

World J Gastroenterol

authors

Chen ZS,Meng FY,Chen XP,Liu DG,Wei L,Jiang JP,Du DF,Zhang WJ,Ming CS,Gong NQ

doi

10.3748/wjg.15.2552

subject

Has Abstract

pub_date

2009-05-28 00:00:00

pages

2552-5

issue

20

eissn

1007-9327

issn

2219-2840

journal_volume

15

pub_type

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