Insulin-like growth factor binding protein-7 induces activation and transdifferentiation of hepatic stellate cells in vitro.

abstract：AIM:To explore the effects of the nucleoside analogues beta-L-D4A and beta-LPA on hepatitis B virus (HBV) promoters. METHODS:Four HBV promoters were amplified by polymerase chain reaction (PCR) and subcloned into the expression vector pEGFP-1. The four recombinants controlled by HBV promoters were confirmed by restric...

journal_title：World journal of gastroenterology

authors： He XX,Lin JS,Chang Y,Zhang YH,Li Y,Wang XY,Xu D,Cheng XM

更新日期：2008-03-28 00:00:00

abstract：AIM:To investigate the timing, safety and efficacy of prophylactic antiviral therapy in patients with hepatitis B virus (HBV) infection undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:This prospective study recruited a total of 57 patients diagnosed with malignant hematological disea...

journal_title：World journal of gastroenterology

authors： Liao YP,Jiang JL,Zou WY,Xu DR,Li J

更新日期：2015-04-14 00:00:00

abstract：AIM:To identify risk factors to help predict which patients are likely to fail to appear for an endoscopic procedure. METHODS:This was a retrospective, chart review, cohort study in a Canadian, tertiary care, academic, hospital-based endoscopy clinic. Patients included were: those undergoing esophagogastroduodenoscopy...

journal_title：World journal of gastroenterology

authors： Wong VK,Zhang HB,Enns R

更新日期：2009-06-21 00:00:00

abstract：AIM:To detect the expression of mitochondrial uncoupling protein 2 (UCP2) in colon cancer and analyze the relation between UCP2 expression and clinical pathological features of colon cancer. METHODS:Fifteen colon tissue samples and 15 its adjacent tissue samples were obtained from colon cancer patients during surgical...

journal_title：World journal of gastroenterology

authors： Kuai XY,Ji ZY,Zhang HJ

更新日期：2010-12-07 00:00:00

abstract：:During the last decade, inflammation (carditis) and intestinal metaplasia localized to immediately below the human gastro-oesophageal junction have received much attention in relation to the rising incidence of cancer at this site. Since these histological findings are frequently observed even among those who are H py...

journal_title：World journal of gastroenterology

authors： Iijima K,Shimosegawa T

更新日期：2006-09-28 00:00:00

abstract：:In this review, we discuss recent advances in nucleic acid-based therapeutic technologies that target hepatitis C virus (HCV) infection. Because the HCV genome is present exclusively in RNA form during replication, various nucleic acid-based therapeutic approaches targeting the HCV genome, such as ribozymes, aptamers,...

journal_title：World journal of gastroenterology

authors： Lee CH,Kim JH,Lee SW

更新日期：2013-12-21 00:00:00

abstract：AIM:To compare the performance of the Da-an real-time hepatitis B virus (HBV) DNA assay and Abbott RealTime HBV assay. METHODS:HBV DNA standards as well as a total of 180 clinical serum samples from patients with chronic hepatitis B were measured using the Abbott and Da-an real-time polymerase chain reaction (PCR) ass...

journal_title：World journal of gastroenterology

authors： Qiu N,Li R,Yu JG,Yang W,Zhang W,An Y,Li T,Liu XE,Zhuang H

更新日期：2014-09-07 00:00:00

abstract：:Ingested fish bone induced intestinal perforations are seldom diagnosed preoperatively due to incomplete patient history taking and difficulties in image evidence identification. Most literature suggests early surgical intervention to prevent sepsis and complications resulting from fish bone migrations. We report the ...

journal_title：World journal of gastroenterology

authors： Kuo CC,Jen TK,Wen CH,Liu CP,Hsiao HS,Liu YC,Chen KH

更新日期：2012-11-07 00:00:00

abstract：AIM:To explore the effects of peptide S-8300 from shark liver (S-8300) on liver function as well as in regulating immune functions in experimental injury models. METHODS:Mice were administered with different doses of S-8300 for four consecutive days, followed by mice injected with tetrachloromethane (CCl(4)) on d 3. T...

journal_title：World journal of gastroenterology

authors： Huang FJ,Lv ZB,Li Q,Wei LJ,Zhang L,Wu WT

更新日期：2005-03-28 00:00:00

abstract：AIM:To study the condition and potentiality of human umbilical cord blood stem cells (HUCBSC) to differentiate into hepatocytes in vivo or in vitro. METHODS:In a cell culture study of human umbilical cord blood stem cell (HUCBSC) differentiation, human umbilical cord blood mononuclear cells (HUCBMNC) were separated by...

journal_title：World journal of gastroenterology

authors： Tang XP,Zhang M,Yang X,Chen LM,Zeng Y

更新日期：2006-07-07 00:00:00

abstract：AIM:To evaluate the impact of early steroid withdrawal on the incidence of rejection, tumor recurrence and complications after liver transplantation for advanced-stage hepatocellular carcinoma. METHODS:Fifty-four patients underwent liver transplantation for advanced-stage hepatocellular carcinoma from April 2003 to Ju...

journal_title：World journal of gastroenterology

authors： Chen ZS,He F,Zeng FJ,Jiang JP,Du DF,Liu B

更新日期：2007-10-21 00:00:00

abstract：AIM:To investigate let-7a expression and analyze the correlation between let-7a and progression of gastric mucosa cancerization. METHODS:The tissue microarray was constructed previously in 52 cases of human gastric carcinoma, 17 cases of chronic atrophic gastritis (atypical hyperplasia) and 11 cases of normal gastric ...

journal_title：World journal of gastroenterology

authors： Zhu YM,Zhong ZX,Liu ZM

更新日期：2010-07-14 00:00:00

abstract：AIM:To find potential mutable sites by detecting mutations of the candidate gene in a kindred with polycystic liver disease (PCLD). METHODS:First, we chose a kindred with PCLD and obtained five venous blood samples of this kindred after the family members signed the informed consent form. In the kindred two cases were...

journal_title：World journal of gastroenterology

authors： Jin S,Cui K,Sun ZQ,Shen YY,Li P,Wang ZD,Li FF,Gong KN,Li S

更新日期：2015-02-28 00:00:00

abstract：AIM:To study the influence of redox environment of Escherichia coli (E. coli) cytoplasm on disulfide bond formation of recombinant proteins. METHODS:Bovine fibroblast growth factor (BbFGF) was selected as a model of simple proteins with a single disulfide bond and free cysteines. Anti-HBsAg single-chain Fv (HBscFv), a...

journal_title：World journal of gastroenterology

authors： Xiong S,Wang YF,Ren XR,Li B,Zhang MY,Luo Y,Zhang L,Xie QL,Su KY

更新日期：2005-02-21 00:00:00

abstract：AIM:Non-bioartificial liver has been applied to clinic for quite a long time, but the reported efficacy has been very different. The aim of this study was to compare the efficacy and safety of hemoperfusion adsorption, plasma exchange and plasma exchange plus hemoperfusion adsorption in treatment of severe viral hepati...

journal_title：World journal of gastroenterology

authors： He NH,Wang YJ,Wang ZW,Liu J,Li JJ,Liu GD,Wang YM

更新日期：2004-04-15 00:00:00

abstract：AIM:To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels. METHODS:Ten male patients with HCV-related chronic hepatitis and 16 healthy male volunteers were studied. In all subjects seminal parameters (nemaspermic concentration...

journal_title：World journal of gastroenterology

authors： Durazzo M,Premoli A,Di Bisceglie C,Bertagna A,Faga E,Biroli G,Manieri C,Bo S,Pagano G

更新日期：2006-05-21 00:00:00

abstract：AIM:To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the ¹³C-octanoic acid breath test in a mouse model. METHODS:Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 mg of egg yolk labeled with 1.5 L/g ¹³C-octanoic ...

journal_title：World journal of gastroenterology

authors： Lim CH,Choi MG,Park H,Baeg MK,Park JM

更新日期：2013-07-21 00:00:00

abstract：AIM:To investigate functional change of dendritic cells (DCs) derived from allogeneic partial liver graft undergoing acute rejection in rats. METHODS:Allogeneic (SD rat to LEW rat) whole and 50 % partial liver transplantation were performed. DCs from liver grafts 0 hr and 4 days after transplantation were isolated and...

journal_title：World journal of gastroenterology

authors： Xu MQ,Yao ZX

更新日期：2003-01-01 00:00:00

abstract：:Alverine citrate is a commonly used smooth muscle relaxant agent. A MEDLINE search on January 2004 revealed only 1 report implicating the hepatotoxicity of this agent. A 34-year-old woman was investigated because of the finding of elevated liver function tests on biochemical screening. Other etiologies of hepatitis we...

journal_title：World journal of gastroenterology

authors： Arhan M,Koklu S,Koksal AS,Yolcu OF,Koruk S,Koruk I,Kayacetin E

更新日期：2004-08-01 00:00:00

abstract：AIM:To investigate the expression of gastrokine 1 (GKN1) in normal gastric mucosa, precancerous lesions and gastric cancer tissues, and to analyse its correlations with tumour site and pathological pattern. METHODS:Thirty gastric cancer patients (12 cases of diffuse type and 18 cases of intestinal type), 13 atrophic g...

journal_title：World journal of gastroenterology

authors： Guo XY,Dong L,Qin B,Jiang J,Shi AM

更新日期：2014-11-28 00:00:00

abstract：AIM:To test the effect of the dephytinization of three different commercial infant cereals on iron, calcium, and zinc bioavailability by estimating the uptake, retention, and transport by Caco-2 cells. METHODS:Both dephytinized (by adding an exogenous phytase) and non-dephytinized infant cereals were digested using an...

journal_title：World journal of gastroenterology

authors： Frontela C,Scarino ML,Ferruzza S,Ros G,Martínez C

更新日期：2009-04-28 00:00:00

abstract：:Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome (OMIM 208085) is an autosomal recessive disorder that is caused by mutations in 2 interacting genes VPS33B and VIPAS39. Mutations in VPS33B gene account for most cases of ARC. As low or normal gamma-glutamyl transpeptidase (GGT) activity has been describ...

journal_title：World journal of gastroenterology

authors： Wang JS,Zhao J,Li LT

更新日期：2014-04-28 00:00:00

abstract：AIM:To look for the evidence of human papilloma virus (HPV) infection in esophageal squamous cell carcinomas (ESCC) and to investigate the potential role and epidemiology of HPV infection in the pathogenesis of esophageal carcinomas in Henan emigrants. METHODS:Papilloma virus(PV) and HPV were determined by Ultrasensiv...

journal_title：World journal of gastroenterology

authors： Yao PF,Li GC,Li J,Xia HS,Yang XL,Huang HY,Fu YG,Wang RQ,Wang XY,Sha JW

更新日期：2006-03-07 00:00:00

abstract：AIM:To assess the role of IgM and IgG immunohistochemistry (IHC) in the evaluation of autoimmune liver conditions--autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC). METHODS:Forty one biopsies from untreated patients diagnosed with autoimmune liver disease (AIH, n = ...

journal_title：World journal of gastroenterology

authors： Moreira RK,Revetta F,Koehler E,Washington MK

更新日期：2010-01-28 00:00:00

abstract：:Hepatoblastoma is the most common primary hepatic tumor of children. However, only a very few cases have been reported in adults. Most studies support treatment with chemotherapy followed by surgical resection. We present the first reported case of adult hepatoblastoma in Taiwan. A 52-year-old female suffered from sud...

journal_title：World journal of gastroenterology

authors： Ke HY,Chen JH,Jen YM,Yu JC,Hsieh CB,Chen CJ,Liu YC,Chen TW,Chan DC

更新日期：2005-10-21 00:00:00

abstract：AIM:To explore the grade and stage of pathology and the relationship between grading and staging of hepatic fibrosis and noninvasive diagnostic parameters. METHODS:Inflammatory activity and fibrosis of consecutive liver biopsies from 200 patients with chronic liver disease were determined according to the Diagnostic C...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Wan MB,Li CZ,Mao YM,Li JQ,Qiu DK,Cao AP,Ye J,Cai X,Chen CW,Wang JY,Wu SM,Zhu JS,Zhou XQ

更新日期：2003-11-01 00:00:00

abstract：AIM:To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS:Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function par...

journal_title：World journal of gastroenterology

authors： Pereira RM,dos Santos RA,Oliveira EA,Leite VH,Dias FL,Rezende AS,Costa LP,Barcelos LS,Teixeira MM,Simoes e Silva AC

更新日期：2008-07-28 00:00:00

abstract：AIM:To perform a meta-analysis of observational studies to further elucidate the relationship between oral bisphosphonate use and gastrointestinal cancer risk. METHODS:Systematic literature search was conducted in MEDLINE, EMBASE, and the Cochrane Library to identify studies through January 2011. Search terms were "bi...

journal_title：World journal of gastroenterology

authors： Oh YH,Yoon C,Park SM

更新日期：2012-10-28 00:00:00

abstract：:Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis in the presence of the intestinal diverticula, surgical enteroanastomoses, blind pouches, afferent loops, incarcerated hernias, small intestinal tumors, intestinal kinking fro...

journal_title：World journal of gastroenterology

authors： Gurvits GE,Lan G

更新日期：2014-12-21 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this article, we describe the clinical course of a patient who developed a pancreatic recurrence of RCC and 1 yea...

journal_title：World journal of gastroenterology

authors： Riviello C,Tanini I,Cipriani G,Pantaleo P,Nozzoli C,Poma A,Riccardo V,Valeri A

更新日期：2006-08-28 00:00:00