Relationship between let-7a and gastric mucosa cancerization and its significance.

abstract：AIM:To investigate the clinical efficacy and toxic effects of neoadjuvant chemotherapy using docetaxel combined with oxaliplatin and fluorouracil for treating stage III/IV gastric cancer. METHODS:A total of 53 stage III/IV gastric cancer patients were enrolled into the study and treated with neoadjuvant chemotherapy. ...

journal_title：World journal of gastroenterology

authors： Yu YJ,Sun WJ,Lu MD,Wang FH,Qi DS,Zhang Y,Li PH,Huang H,You T,Zheng ZQ

更新日期：2014-12-28 00:00:00

abstract：AIM:To study the role of P38 kinase in esophageal cancer cell apoptosis induced by genotoxin, cisplatin and the unfolded protein response (UPR) inducer, dithiothreitol (DTT). METHODS:Esophageal carcinoma cell line Eca109 was cultured in RPMI 1640 medium to 70% confluency and treated with either cisplatin, DTT, or cisp...

journal_title：World journal of gastroenterology

authors： Zhang QX,Feng R,Zhang W,Ding Y,Yang JY,Liu GH

更新日期：2005-08-07 00:00:00

abstract：:Oncological treatment is currently directed toward a tailored therapy concept. Squamous cell carcinoma of the anal canal could be considered a suitable platform to test new therapeutic strategies to minimize treatment morbidity. Standard of care for patients with anal canal cancer consists of a combination of radiothe...

journal_title：World journal of gastroenterology

authors： De Nardi P,Carvello M,Staudacher C

更新日期：2012-11-28 00:00:00

abstract：AIM:To investigate the effect of epigallocatechin gallate (EGCG) on structural changes of gut microbiota in colorectal carcinogenesis. METHODS:An azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colitis mouse model was established. Forty-two female FVB/N mice were randomly divided into the following three group...

journal_title：World journal of gastroenterology

authors： Wang X,Ye T,Chen WJ,Lv Y,Hao Z,Chen J,Zhao JY,Wang HP,Cai YK

更新日期：2017-12-14 00:00:00

abstract：AIM:To investigate the efficacy of exercise interventions on hepatic fat mobilization in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:Ovid-Medline, PubMed, EMBASE and Cochrane database were searched for randomized trials and prospective cohort studies in adults aged ≥ 18 which investigated the effects o...

journal_title：World journal of gastroenterology

authors： Golabi P,Locklear CT,Austin P,Afdhal S,Byrns M,Gerber L,Younossi ZM

更新日期：2016-07-21 00:00:00

abstract：AIM:To investigate the optimum period of treatment for post endoscopic submucosal dissection (ESD) ulcers. METHODS:Patients who underwent ESD for gastric cancer were randomized to two groups and treated with esomeprazole 20 mg per day for 4 wk (4W group) or 2 wk (2W group). At 4 wk after ESD, we measured the size of t...

journal_title：World journal of gastroenterology

authors： Arai M,Matsumura T,Okimoto K,Oyamada A,Saito K,Minemura S,Maruoka D,Tanaka T,Nakagawa T,Katsuno T,Yokosuka O

更新日期：2014-11-21 00:00:00

abstract：AIM:To investigate the biological function of complete S protein and to look for proteins interacting with complete S protein in hepatocytes. METHODS:We constructed bait plasmid expressing complete S protein of HBV by cloning the gene of complete S protein into pGBKT7, then the recombinant plasmid DNA was transformed ...

journal_title：World journal of gastroenterology

authors： Bai GQ,Cheng J,Zhang SL,Huang YP,Wang L,Liu Y,Lin SM

更新日期：2005-07-07 00:00:00

abstract：:Tumors of the minor papilla of the duodenum are quite rare. We successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy. A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by uppe...

journal_title：World journal of gastroenterology

authors： Kanamori A,Kumada T,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Toyoda H,Kawashima H,Itoh A,Hirooka Y,Goto H

更新日期：2009-03-07 00:00:00

abstract：:The incidence of adenocarcinoma of the esophago-gastric junction is constantly increasing. Curative treatment is no longer possible at the time of diagnosis in more than 50% of patients with esophageal carcinoma, and palliative treatment focusing on eliminating dysphagia is required. Endoscopic therapy with stent impl...

journal_title：World journal of gastroenterology

authors： Aymaz S,Dormann AJ

更新日期：2008-06-28 00:00:00

abstract：AIM:To study the relationship between Helicobacter pylori (H. pylori) and gastric carcinoma and its possible pathogenesis by H. pylori. METHODS:DNEL technique and immunohistochemical technique were used to study the state of apoptosis, proliferation and p53 gene expression. A total of 100 gastric mucosal biopsy specim...

journal_title：World journal of gastroenterology

authors： Zhang Z,Yuan Y,Gao H,Dong M,Wang L,Gong YH

更新日期：2001-12-01 00:00:00

abstract：AIM:To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS:...

journal_title：World journal of gastroenterology

authors： Jiang M,Liu F,Xiong WJ,Zhong L,Chen XM

更新日期：2008-11-14 00:00:00

abstract：:A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He...

journal_title：World journal of gastroenterology

authors： Sayana H,Yousef O,Clarkston WK

更新日期：2013-11-14 00:00:00

abstract：AIM:To assess the efficacy and safety of combined directly acting antivirals (DAAs) for the treatment of Chinese chronic hepatitis C (CHC) patients in a real-world setting. METHODS:Hospitalized CHC patients who were treated with DAAs at Peking University First Hospital between January 2015 and December 2016 were enrol...

journal_title：World journal of gastroenterology

authors： Chen JH,Zeng Z,Zhang XX,Zhang Y,Zhang RW,Wang S,Wu CH,Yu M,Liu D,Xi HL,Zhou YX,An YY,Xu XY

更新日期：2017-06-14 00:00:00

abstract：AIM:To evaluate the feasibility of quantifying liver choline concentrations in both normal and apoptotic rabbit livers in vivo, using 1H magnetic resonance spectroscopy (1H-MRS). METHODS:1H-MRS was performed in 18 rabbits using a 1.5T GE MR system with an eight-channel head/neck receiving coil. Fifteen rabbits were in...

journal_title：World journal of gastroenterology

authors： Shen ZW,Cao Z,You KZ,Yang ZX,Xiao YY,Cheng XF,Chen YW,Wu RH

更新日期：2012-03-14 00:00:00

abstract：:A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99...

journal_title：World journal of gastroenterology

authors： Sano S,Yamagami K,Tanaka A,Nishio M,Nakamura T,Kubo Y,Inoue T,Ueda W,Okawa K,Yoshioka K

更新日期：2008-10-21 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：:Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though only on the basis of...

journal_title：World journal of gastroenterology

authors： Fedeli U,Girardi P,Mastrangelo G

更新日期：2019-09-07 00:00:00

abstract：:As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When con...

journal_title：World journal of gastroenterology

authors： Tenner S

更新日期：2014-11-28 00:00:00

abstract：AIM:To investigate the effects of butyrate on interleukin (IL)-32alpha expression in epithelial cell lines. METHODS:The human intestinal epithelial cell lines HT-29, SW480, and T84 were used. Intracellular IL-32alpha was determined by Western blotting analyses. IL-32alpha mRNA expression was analyzed by real-time poly...

journal_title：World journal of gastroenterology

authors： Kobori A,Bamba S,Imaeda H,Ban H,Tsujikawa T,Saito Y,Fujiyama Y,Andoh A

更新日期：2010-05-21 00:00:00

abstract：AIM:To classify gallstone disease as a basis for assessment of post-cholecystectomy symptoms. METHODS:One hundred and fifty three patients with a clinical and ultrasonographic diagnosis of gallstones filled out a structured questionnaire on abdominal pain symptoms and functional gastrointestinal disorder (FGID) before...

journal_title：World journal of gastroenterology

authors： Schmidt M,Søndenaa K,Dumot JA,Rosenblatt S,Hausken T,Ramnefjell M,Njølstad G,Eide GE

更新日期：2012-03-28 00:00:00

abstract：AIM:To evaluate the impact of hepatitis C virus (HCV) infection with genotype 1 or 3 and the presence or absence of liver cirrhosis (LC) in the early viral kinetics response to treatment. METHODS:Naive patients (n = 46) treated with interferon-alpha (IFN-alpha) and ribavirin and followed up with frequent early HCV-RNA...

journal_title：World journal of gastroenterology

authors： Medeiros-Filho JE,de Carvalho Mello IM,Pinho JR,Neumann AU,de Mello Malta F,da Silva LC,Carrilho FJ

更新日期：2006-12-07 00:00:00

abstract：AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

journal_title：World journal of gastroenterology

authors： Tan YW,Zhou XB,Ye Y,He C,Ge GH

更新日期：2017-08-21 00:00:00

abstract：AIM:To compare two different laparotomy methods for modeling rabbit VX2 hepatocarcinoma. METHODS:Thirty New Zealand rabbits were randomly divided into two groups: A and B. Group A was assigned a traditional laparotomy method (embedding tumor fragments directly into the liver with tweezers). Group B was subjected to an...

journal_title：World journal of gastroenterology

authors： Chen Z,Kang Z,Xiao EH,Tong M,Xiao YD,Li HB

更新日期：2015-04-28 00:00:00

abstract：AIM:To investigate whether common variants in the oxidative pathway genes influence inflammatory bowel disease (IBD) risk among Moroccan patients. METHODS:The distribution of (TAAA)n_rs12720460 and (CCTTT)n _rs3833912 NOS2A microsatellite repeats, HIF-1A_rs11549467 and NFKB1-94ins/delATTG_rs28362491 was analyzed in 50...

journal_title：World journal of gastroenterology

authors： Senhaji N,Nadifi S,Zaid Y,Serrano A,Rodriguez DAL,Serbati N,Karkouri M,Badre W,Martín J

更新日期：2017-12-21 00:00:00

abstract：AIM:To conduct a multicentre retrospective review of virological response rates in Asians infected with genotype 1 chronic hepatitis C (CHC) treated with combination interferon and ribavirin and then to compare their responses to that among Caucasians. METHODS:Asian patients infected with genotype 1 CHC treated at 4 A...

journal_title：World journal of gastroenterology

authors： Yan KK,Guirgis M,Dinh T,George J,Dev A,Lee A,Zekry A

更新日期：2008-06-07 00:00:00

abstract：AIM:Small intestinal bacterial overgrowth (SIBO) may contribute to the appearance of several gastrointestinal nonspecific symptoms. Acute diverticulitis is affected by some similar symptoms and bacterial colonic overgrowth. We assessed the prevalence of SIBO in acute uncomplicated diverticulitis and evaluated its influ...

journal_title：World journal of gastroenterology

authors： Tursi A,Brandimarte G,Giorgetti GM,Elisei W

更新日期：2005-05-14 00:00:00

abstract：AIM:To evaluate the importance of endoscopic ultrasonography (EUS) for small (≤ 10 mm) rectal neuroendocrine tumor (NET) treatment. METHODS:Patients in whom rectal NETs were diagnosed by endoscopic resection (ER) at the Pusan National University Yangsan Hospital between 2008 and 2014 were included in this study. A tot...

journal_title：World journal of gastroenterology

authors： Park SB,Kim DJ,Kim HW,Choi CW,Kang DH,Kim SJ,Nam HS

更新日期：2017-03-21 00:00:00

abstract：AIM:To establish the frequency of hyperphosphatemia following the administration of sodium phosphate laxatives in low-risk patients. METHODS:One hundred consecutive ASA I-II individuals aged 35-74 years, who were undergoing colonic cleansing with oral sodium phosphate (OSP) before colonoscopy were recruited for this p...

journal_title：World journal of gastroenterology

authors： Casais MN,Rosa-Diez G,Pérez S,Mansilla EN,Bravo S,Bonofiglio FC

更新日期：2009-12-21 00:00:00

abstract：:AIM:To observe the tumor inhibitory effects by transfecting IL-6 cDNA into colon cancer cell line HT-29 with retroviral vector pZIP cDNA.METHODS:Human IL-6 gene was reconstructed in retrovirus vector and transfected into incasing cells PA317 by lipofectamine mediated method, the clones of the cells transferred with hI...

journal_title：World journal of gastroenterology

authors： Xiao B,Jing B,Zhang YL,Zhou DY,Zhang WD

更新日期：2000-02-01 00:00:00

abstract：AIM:To evaluate the efficacy and tolerability of herbal medicines in inflammatory bowel disease (IBD) by conducting a meta-analysis. METHODS:Electronic databases were searched for studies investigating efficacy and/or tolerability of herbal medicines in the management of different types of IBD. The search terms were: ...

journal_title：World journal of gastroenterology

authors： Rahimi R,Nikfar S,Abdollahi M

更新日期：2013-09-14 00:00:00