Treatment responses in Asians and Caucasians with chronic hepatitis C infection.

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00

abstract：AIM:To establish an animal model with human hepatocyte-repopulated liver for the study of liver cancer metastasis. METHODS:Cell transplantation into mouse livers was conducted using alpha-fetoprotein (AFP)-producing human gastric cancer cells (h-GCCs) and h-hepatocytes as donor cells in a transgenic mouse line express...

journal_title：World journal of gastroenterology

authors： Fujiwara S,Fujioka H,Tateno C,Taniguchi K,Ito M,Ohishi H,Utoh R,Ishibashi H,Kanematsu T,Yoshizato K

更新日期：2012-08-07 00:00:00

abstract：AIM:To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA). METHODS:WB-F344 cells were continuously exposed to 7 x 10(-7) mol/L H2O2 for 21 d. Observations of cell morphology, colony formation rates, flow cyt...

journal_title：World journal of gastroenterology

authors： Han YY,Xue XW,Shi ZM,Wang PY,Wu XR,Wang XJ

更新日期：2014-02-07 00:00:00

abstract：AIM:To investigate the aberrant expression of nuclear matrix proteins in human gastric cancer cells before and after hexamethylene bisacetamide (HMBA) treatment. METHODS:Proteomics analysis of differential nuclear matrix proteins was performed by two dimensional electrophoresis polyacrylamide gel electrophoresis and m...

journal_title：World journal of gastroenterology

authors： Jing GJ,Xu DH,Shi SL,Li QF,Wang SY,Wu FY,Kong HY

更新日期：2010-05-07 00:00:00

abstract：:Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutations in the hemojuvelin, hepcidin, transferrin receptor 2 and ferroportin genes. Juvenile haemochromatosis...

journal_title：World journal of gastroenterology

authors： Wallace DF,Subramaniam VN

更新日期：2007-09-21 00:00:00

abstract：:Many of the drugs currently used in medical practice are racemates. The enantiomers of a racemic drug differ in pharmacodynamics and/or pharmacokinetics, thus in some cases it is preferable to develop pure enantiomers by racemic switch. In a recent study by Pai et al, dexrabeprazole [R(+)-rabeprazole] (10 mg) was foun...

journal_title：World journal of gastroenterology

authors： Zhou Q,Yan XF,Pan WS,Zeng S

更新日期：2008-04-28 00:00:00

abstract：:In order to have an adequate view of the whole small intestine during capsule endoscopy, the preparation recommended consists of a clear liquid diet and an overnight fast. However, visualization of the small bowel during video capsule endoscopy can be impaired by intestinal contents. To improve mucosal visualization, ...

journal_title：World journal of gastroenterology

authors： Pons Beltrán V,Carretero C,Gonzalez-Suárez B,Fernandez-Urien I,Muñoz-Navas M

更新日期：2008-10-07 00:00:00

abstract：:A 46-year-old female patient with terminal ileum Crohn's disease and ankylosing spondylitis presented with recurrent angioedema and urticaria. Investigations ruled out hereditary angioedema, and environmental or food allergen triggers. She was diagnosed with chronic idiopathic urticaria with angioedema, and was treate...

journal_title：World journal of gastroenterology

authors： Habal F,Huang V

更新日期：2012-09-14 00:00:00

abstract：AIM:To evaluate the efficacy and safety of capsule oxymatrine in the treatment of chronic hepatitis B. METHODS:A randomised double-blind and placebo-controlled multicenter trial was conducted. Injection of oxymatrine was used as positive-control drug. A total of 216 patients with chronic hepatitis B entered the study ...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Mao YM,Li JQ,Wan MB,Li CZ,Chen CW,Fu QC,Wang JY,She WM,Cai X,Ye J,Zhou XQ,Wang H,Wu SM,Tang MF,Zhu JS,Chen WX,Zhang HQ

更新日期：2003-11-01 00:00:00

abstract：AIM:Granuloma is considered the hallmark of microscopic diagnosis in Crohn's disease (CD), but granulomas can be detected in only 21-60% of CD patients. The aim of this study was to evaluate the frequency of granulomas by multiple endoscopic biopsies in patients with CD and to examine whether group of patients with or ...

journal_title：World journal of gastroenterology

authors： Molnár T,Tiszlavicz L,Gyulai C,Nagy F,Lonovics J

更新日期：2005-05-28 00:00:00

abstract：:Microscopic colitis may be defined as a clinical syndrome, of unknown etiology, consisting of chronic watery diarrhea, with no alterations in the large bowel at the endoscopic and radiologic evaluation. Therefore, a definitive diagnosis is only possible by histological analysis. The epidemiological impact of this dise...

journal_title：World journal of gastroenterology

authors： Ianiro G,Cammarota G,Valerio L,Annicchiarico BE,Milani A,Siciliano M,Gasbarrini A

更新日期：2012-11-21 00:00:00

abstract：AIM:To evaluate the prognostic power of different molecular data in liver cancer. METHODS:Cox regression screen and least absolute shrinkage and selection operator were performed to select significant prognostic variables. Then the concordance index was calculated to evaluate the prognostic power. For the combination ...

journal_title：World journal of gastroenterology

authors： Song YZ,Li X,Li W,Wang Z,Li K,Xie FL,Zhang F

更新日期：2018-07-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) is a well-known human pathogen that plays an essential role in the pathogenesis of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although H. pylori is susceptible to several antimicrobials, this infection has proven challenging to cure because of the increasing prev...

journal_title：World journal of gastroenterology

authors： Federico A,Gravina AG,Miranda A,Loguercio C,Romano M

更新日期：2014-01-21 00:00:00

abstract：AIM:To investigate the protective effect of stronger neo-minophafen C (SNMC) on fulminant hepatic failure (FHF) and its underlying mechanism. METHODS:A mouse model of FHF was established by intraperitoneal injection of galactosamine (D-Gal N) and lipopolysaccharide (LPS). The survival rate, liver function, inflammator...

journal_title：World journal of gastroenterology

authors： Yang BS,Ma YJ,Wang Y,Chen LY,Bi MR,Yan BZ,Bai L,Zhou H,Wang FX

更新日期：2007-01-21 00:00:00

abstract：AIM:To assess whether trace metal concentrations (which influence metabolism as both essential and non-essential elements) are increased or decreased in cancerous tissues and to understand the precise role of these metals in carcinogenesis. METHODS:Concentrations of trace metals including Cd, Ni, Cu, Zn, Fe, Mg and Ca...

journal_title：World journal of gastroenterology

authors： Yaman M,Kaya G,Yekeler H

更新日期：2007-01-28 00:00:00

abstract：AIM:To compare the therapeutic effects of proton pump inhibitors vs H₂ receptor antagonists for upper gastrointestinal bleeding in patients after successful endoscopy. METHODS:We searched the Cochrane library, MEDLINE, EMBASE and PubMed for randomized controlled trials until July 2014 for this study. The risk of bias ...

journal_title：World journal of gastroenterology

authors： Zhang YS,Li Q,He BS,Liu R,Li ZJ

更新日期：2015-05-28 00:00:00

abstract：:The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

journal_title：World journal of gastroenterology

authors： Goh BK

更新日期：2015-09-14 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography (ERCP) is a state of the art diagnostic and therapeutic procedure for various pancreatic and biliary problems. In spite of the well-established safety of the procedure, there is still a risk of complications such as pancreatitis, cholangitis, bleeding and perforation. Air...

journal_title：World journal of gastroenterology

authors： Yilmaz B,Roach EC,Koklu S,Aydin O,Unlu O,Kilic YA

更新日期：2015-04-21 00:00:00

abstract：:AIM:It is well known that colonoscopy can be difficult due to abdominal pain induced during colonoscope insertion, if sedative agents are not given. Recently, an extra-flexible, small-diameter colonoscope (CF-SV, Olympus Inc.Japan) was developed in order to improve safety and comfort. The aim of this study was to acce...

journal_title：World journal of gastroenterology

authors： Han Y,Uno Y,Munakata A

更新日期：2000-10-01 00:00:00

abstract：:The technique of endoscopic submucosal dissection (ESD), which was developed for en bloc resection of large lesions in the stomach, has been widely accepted for the treatment of the entire gastrointestinal tract. Many minimally invasive endoscopic therapies based on ESD have been developed recently. Endoscopic submuco...

journal_title：World journal of gastroenterology

authors： Zhou PH,Shi Q,Zhong YS,Yao LQ

更新日期：2013-11-07 00:00:00

abstract：AIM:To investigate whether autofluorescence imaging (AFI) endoscopy can distinguish non-erosive reflux disease (NERD) from functional heartburn (FH). METHODS:In this prospective observational trial, 127 patients presenting with typical reflux symptoms for > 6 mo were screened. All the participants underwent endoscopy,...

journal_title：World journal of gastroenterology

authors： Luo X,Guo XX,Wang WF,Peng LH,Yang YS,Uedo N

更新日期：2016-04-14 00:00:00

abstract：AIM:To investigate whether the degree of rectal distension could define the rectum functions as a conduit or reservoir. METHODS:Response of the rectal and anal pressure to 2 types of rectal balloon distension, rapid voluminous and slow gradual distention, was recorded in 21 healthy volunteers (12 men, 9 women, age 41....

journal_title：World journal of gastroenterology

authors： Shafik A,Mostafa RM,Shafik I,Ei-Sibai O,Shafik AA

更新日期：2006-07-28 00:00:00

abstract：:According to a meta-analysis, H pylori and non-steroidal anti-inflammatory drugs (NSAID) independently and significantly increase the risk of gastroduodenal ulcer and ulcer bleeding. Their coincidence is frequent, demonstration of a possible relationship and consequent attitude is of important implications. But unfort...

journal_title：World journal of gastroenterology

authors： Ji KY,Hu FL

更新日期：2006-06-28 00:00:00

abstract：:Neurofibromas of the large bowel are very rare and usually are part of the colonic involvement in neurofibromatosis type 1 (Nf1, von Recklinghausen's disease). Solitary neurofibromas of the colon are extremely rare. We describe a case of an isolated neurofibroma that was found in the large bowel of a patient who suffe...

journal_title：World journal of gastroenterology

authors： Panteris V,Vassilakaki T,Vaitsis N,Elemenoglou I,Mylonakou I,Karamanolis DG

更新日期：2005-09-21 00:00:00

abstract：AIM:To identify the prevalence of hepatitis B e antigen (HBeAg) and to assess the association of hepatitis B virus (HBV) core promoter mutations and viral load in Indonesian patients. METHODS:Sixty-four patients with chronic hepatitis, 65 with liver cirrhosis and 50 with hepatocellular carcinoma were included in this ...

journal_title：World journal of gastroenterology

authors： Utama A,Siburian MD,Purwantomo S,Intan MD,Kurniasih TS,Gani RA,Achwan WA,Arnelis,Lelosutan SA,Lukito B,Harmono T,Zubir N,Julius,Soemohardjo S,Lesmana LA,Sulaiman A,Tai S

更新日期：2011-02-14 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is a critical risk factor for the carcinogenesis and progression of hepatocellular carcinoma (HCC). It promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Effective antiviral treatments...

journal_title：World journal of gastroenterology

authors： Zhang YQ,Guo JS

更新日期：2015-04-07 00:00:00

abstract：AIM:To investigate the effects of butyrate on interleukin (IL)-32alpha expression in epithelial cell lines. METHODS:The human intestinal epithelial cell lines HT-29, SW480, and T84 were used. Intracellular IL-32alpha was determined by Western blotting analyses. IL-32alpha mRNA expression was analyzed by real-time poly...

journal_title：World journal of gastroenterology

authors： Kobori A,Bamba S,Imaeda H,Ban H,Tsujikawa T,Saito Y,Fujiyama Y,Andoh A

更新日期：2010-05-21 00:00:00

abstract：AIM:To assess the clinicopathological and biological significance of cripto in human colorectal cancer. METHODS:Real-time reverse-transcription polymerase chain reaction (PCR) was used to examine cripto mRNA levels in primary colon cancer and normal colon tissues as well as normal and metastatic lymph nodes from colon...

journal_title：World journal of gastroenterology

authors： Jiang PC,Zhu L,Fan Y,Zhao HL

更新日期：2013-12-14 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive storage of fatty acids in the form of triglycerides in hepatocytes. It is most prevalent in western countries and includes a wide range of clinical and histopathological findings, namely from simple steatosis to steatohepatitis and fibrosis, which...

journal_title：World journal of gastroenterology

authors： Katsarou A,Moustakas II,Pyrina I,Lembessis P,Koutsilieris M,Chatzigeorgiou A

更新日期：2020-05-07 00:00:00

abstract：AIM:H101, an E1B 55 kD gene deleted adenovirus, has been shown to possess oncolysis activity experimentally and proved to be safe in preliminary phase I study. The current study was designed to evaluate its anti-tumor activity and toxicity in combination with chemotherapy in patients with late stage cancers. METHODS:H...

journal_title：World journal of gastroenterology

authors： Lu W,Zheng S,Li XF,Huang JJ,Zheng X,Li Z

更新日期：2004-12-15 00:00:00