Tumor growth inhibition effect of hIL-6 on colon cancer cells transfected with the target gene by retroviral vector.

abstract：AIM:To clarify the molecular mechanism involved in pathogenesis of colorectal cancer as well as clinical significance of genetic analysis of histological samples. METHODS:A total of 480 blood and tissue specimens were collected in our hospital from January 2011 to October 2012. In the observation group, there were 120...

journal_title：World journal of gastroenterology

authors： Yan ZH,Cui LH,Wang XH,Li C,He X

更新日期：2014-12-28 00:00:00

abstract：AIM:To investigate the role of nuclear division cycle (NDC)80 in human hepatocellular carcinogenesis. METHODS:NDC80 gene expression was analyzed by real-time reverse transcription polymerase chain reaction in 47 paired hepatocellular carcinoma (HCC) and adjacent tissues. The HCC cell line SMMC-7721 was transfected wit...

journal_title：World journal of gastroenterology

authors： Ju LL,Chen L,Li JH,Wang YF,Lu RJ,Bian ZL,Shao JG

更新日期：2017-05-28 00:00:00

abstract：AIM:To prospectively evaluate the effectiveness and safety of continuous wound infiltration (CWI) for pain management after open gastrectomy. METHODS:Seventy-five adult patients with American Society of Anesthesiologists (ASA) Physical Status Classification System (ASA) grade 1-3 undergoing open gastrectomy were rando...

journal_title：World journal of gastroenterology

authors： Zheng X,Feng X,Cai XJ

更新日期：2016-02-07 00:00:00

abstract：:Primary rectal lymphoma is a rare presentation of gastrointestinal lymphomas. Its clinical presentation is indistinguishable from that of rectal carcinoma. Although surgical resection is often technically feasible, optimal therapy for colorectal lymphoma has not yet been identified. We report a case of primary rectal ...

journal_title：World journal of gastroenterology

authors： Bilsel Y,Balik E,Yamaner S,Bugra D

更新日期：2005-01-21 00:00:00

abstract：AIM:To determine the in vivo and in vivo effects of cysteamine (CS) on expression and activity of H(+)-K(+)-ATPase of gastric mucosal cells in weaning piglets. METHODS:Eighteen litters of newborn Xinhuai piglets were employed in the in vivo experiment and allocated to control and treatment groups. From 12 d of age (D1...

journal_title：World journal of gastroenterology

authors： Shi ZM,Du GM,Wei XH,Zhang L,Chen J,Zhao RQ

更新日期：2005-11-14 00:00:00

abstract：:Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin. However, this beneficial effect does not extend to the ...

journal_title：World journal of gastroenterology

authors： Lué A,Lanas A

更新日期：2016-12-28 00:00:00

abstract：:More than 30 years after the discovery of human hepatitis B virus (HBV) this virus remains to be one of the major global health problems. In infected adolescents or adults, 5%-10% will lead to a chronic carrier state, whereas in infected neonates up to 90% develop chronicity. It is estimated that about 370 million peo...

journal_title：World journal of gastroenterology

authors： Glebe D

更新日期：2007-01-07 00:00:00

abstract：:Functional dyspepsia is a common clinical condition characterised by chronic or recurrent upper abdominal pain or discomfort commonly associated with a variety of associated gastrointestinal symptoms and a normal endoscopy. To standardise research-based approaches, an initial categorisation of into sub groups was agre...

journal_title：World journal of gastroenterology

authors： Baker G,Fraser RJ,Young G

更新日期：2006-05-07 00:00:00

abstract：:A variety of hepatic and biliary tract disorders may complicate the clinical course of celiac disease. Some of these have been hypothesized to share common genetic factors or have a common immunopathogenesis, such as primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune forms of hepatitis or cholang...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2006-03-14 00:00:00

abstract：AIM:To analyze the role of rs12979860 and rs8099917 polymorphisms in hepatitis C virus (HCV) genotype 1 infection of Brazilians. METHODS:A total of 145 adult patients diagnosed with genotype 1 chronic hepatitis C (CHC) who had completed a 48-wk regimen of pegylated-interferon α-2a or -2b plus ribavirin combination the...

journal_title：World journal of gastroenterology

authors： Garcia RF,Moreira S,de Araújo Ramos AL,Ferreira LE,de Mattos AA,Tovo CV,Nader LA,Ramos JA,Rondinelli E,de Jesus Dominici A,Garcia CE,de Souza Leite Pinho M,Brandão-Mello CE,Villela-Nogueira CA,de França PH

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：AIM:To examine the calcium metabolism of colorectal cancer (CRC) in patients with colorectal cancer and control patients. METHODS:Seventy newly diagnosed CRC patients were included. The healthy control group was age and gender matched (n=32). Particular attention was devoted to the relationship between serum calcium o...

journal_title：World journal of gastroenterology

authors： Fuszek P,Lakatos P,Tabak A,Papp J,Nagy Z,Takacs I,Horvath HC,Lakatos PL,Speer G

更新日期：2004-07-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is a common complication after liver transplantation, and it is associated with multiple direct and indirect effects. Management of CMV infection and disease has evolved over the years, and clinical guidelines have been recently updated. Universal antiviral prophylaxis and a pre-emptive...

journal_title：World journal of gastroenterology

authors： Marcelin JR,Beam E,Razonable RR

更新日期：2014-08-21 00:00:00

abstract：AIM:To discuss the expression of human leukocyte antigen (HLA) class I antigens in gastric cancer and correlate these with pathologic type and TNM stage. METHODS:The expression of HLA class I antigen was detected by immunohistochemistry in 185 specimens of gastric cancer, 20 gastric cancer specimens with lymphatic met...

journal_title：World journal of gastroenterology

authors： Shen YQ,Zhang JQ,Miao FQ,Zhang JM,Jiang Q,Chen H,Shan XN,Xie W

更新日期：2005-06-21 00:00:00

abstract：AIM:To retrospectively evaluate the imaging features of pancreatic intraductal papillary mucinous neoplasms (IPMNs) in multi-detector row computed tomography (MDCT). METHODS:A total of 20 patients with pathologically-confirmed intraductal papillary mucinous neoplasms (IPMNs) were included in this study. Axial MDCT ima...

journal_title：World journal of gastroenterology

authors： Tan L,Zhao YE,Wang DB,Wang QB,Hu J,Chen KM,Deng XX

更新日期：2009-08-28 00:00:00

abstract：:Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). T...

journal_title：World journal of gastroenterology

authors： Tomimaru Y,Nagano H,Marubashi S,Kobayashi S,Eguchi H,Takeda Y,Tanemura M,Kitagawa T,Umeshita K,Hashimoto N,Yoshikawa H,Wakasa K,Doki Y,Mori M

更新日期：2009-09-07 00:00:00

abstract：:AIM:To explore the status of extrahepatic hepatitis C virus (HCV) infection and replication in hepatitis C patients,and its potential implication in HCV infection and pathogenicity.METHODS:By reverse-transcriptase poly-merase chain reaction (RT-PCR),in situ hybridization (ISH) and immunohis-tochemistry, HCV RNA, HCV r...

journal_title：World journal of gastroenterology

authors： Yan FM,Chen AS,Hao F,Zhao XP,Gu CH,Zhao LB,Yang DL,Hao LJ

更新日期：2000-12-01 00:00:00

abstract：AIM:To evaluate the detection and differentiation ability of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in hepatocellular carcinoma (HCC) operations. METHODS:Clinical data of 50 HCC patients were retrospective analyzed. The sensitivity, specificity, false negative and false positive rates of contrast e...

journal_title：World journal of gastroenterology

authors： Wu H,Lu Q,Luo Y,He XL,Zeng Y

更新日期：2010-01-28 00:00:00

abstract：AIM:To investigate the relationship between certain biochemical parameters of lipid metabolism in the serum and steatosis in the liver. METHODS:The grade of steatosis (0-3) and histological activity index (HAI, 0-18) in liver biopsy specimens were correlated with serum alanine aminotransferase (ALT), total cholesterol...

journal_title：World journal of gastroenterology

authors： Jármay K,Karácsony G,Nagy A,Schaff Z

更新日期：2005-11-07 00:00:00

abstract：AIM:To explore the regulator of G-protein signaling 5 (RGS5) expression in gastric carcinoma and its association with differentiation and microvascular density (MVD). METHODS:Expression of RGS5 and CD34 were examined in 76 cases of gastric carcinoma, including 22 cases with lymph node metastasis and 54 cases without l...

journal_title：World journal of gastroenterology

authors： Wang JH,Huang WS,Hu CR,Guan XX,Zhou HB,Chen LB

更新日期：2010-11-28 00:00:00

abstract：:Endoclip migration into the common bile duct following laparoscopic cholecystectomy (LC) is an extremely rare complication. Migrated endoclip into the common bile duct can cause obstruction, serve as a nidus for stone formation, and cause cholangitis. We report a case of obstructive jaundice and acute biliary pancreat...

journal_title：World journal of gastroenterology

authors： Dolay K,Alis H,Soylu A,Altaca G,Aygun E

更新日期：2007-12-21 00:00:00

abstract：:Elastography-based liver stiffness measurement (LSM) is a non-invasive tool for estimating liver fibrosis but also provides an estimate for the severity of portal hypertension in patients with advanced chronic liver disease (ACLD). The presence of varices and especially of varices needing treatment (VNT) indicates dis...

journal_title：World journal of gastroenterology

authors： Paternostro R,Reiberger T,Bucsics T

更新日期：2019-01-21 00:00:00

abstract：:Diarrhea after bariatric procedures, mainly those with malabsorptive elements including Roux-Y Gastric Bypass and Biliopancreatic Diversion, is common and an essential determinant of quality of life and micro- and macronutrient deficiencies. Bariatric surgery is the only sustainably successful method to address morbid...

journal_title：World journal of gastroenterology

authors： Borbély YM,Osterwalder A,Kröll D,Nett PC,Inglin RA

更新日期：2017-07-14 00:00:00

abstract：AIM:To investigate the effects of sodium alginate (AL-Na) on indomethacin-induced small intestinal lesions in rats. METHODS:Gastric injury was assessed by measuring ulcerated legions 4 h after indomethacin (25 mg/kg) administration. Small intestinal injury was assessed by measuring ulcerated legions 24 h after indomet...

journal_title：World journal of gastroenterology

authors： Yamamoto A,Itoh T,Nasu R,Nishida R

更新日期：2014-03-14 00:00:00

abstract：:Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pa...

journal_title：World journal of gastroenterology

authors： Lin QJ,Yang F,Jin C,Fu DL

更新日期：2015-07-14 00:00:00

abstract：AIM:To evaluate the efficacy of stents in treating patients with anastomotic site obstructions due to cancer recurrence following colorectal surgery. METHODS:The medical records of patients who underwent endoscopic self-expanding metal stents (SEMS) insertion for colorectal obstructions between February 2004 and Janua...

journal_title：World journal of gastroenterology

authors： Kim JH,Lee JJ,Cho JH,Kim KO,Chung JW,Kim YJ,Kwon KA,Park DK,Kim JH

更新日期：2014-10-14 00:00:00

abstract：:We report the first case of single port laparoscopic right hemicolectomy for advanced colon cancer. An abdominal 3 cm length incision was made via the umbilicus. A small wound retractor and a surgical glove were used as a single port. All soft tissue anterior to the superior mesenteric vein was completely removed and ...

journal_title：World journal of gastroenterology

authors： Choi SI,Lee KY,Park SJ,Lee SH

更新日期：2010-01-14 00:00:00

abstract：:In recent years, a number of studies detected a significantly higher prevalence of Campylobacter species such as Campylobacter concisus (C. concisus) in intestinal biopsies and fecal samples collected from patients with inflammatory bowel disease (IBD) compared to controls. Most of these Campylobacter species are not ...

journal_title：World journal of gastroenterology

authors： Zhang L

更新日期：2015-08-21 00:00:00

abstract：:The annual incidence of adenocarcinoma arising from Barrett's esophagus (BE) is approximately 0.5%. Through a process of gradual transformation from low-grade dysplasia to high-grade dysplasia (HGD), adenocarcinoma can develop in the setting of BE. The clinical importance of appropriate identification and treatment of...

journal_title：World journal of gastroenterology

authors： Chennat J,Waxman I

更新日期：2010-08-14 00:00:00

abstract：:Folate deficiency and its association with cancer have been studied in the literature, but its clinical impact is still unknown. Folate deficiency and its result on gastric cancer is a mysterious part of oncology, with ongoing studies hopefully clarifying its impact on gastric cancer management. Lee et al studied fola...

journal_title：World journal of gastroenterology

authors： Alkan A,Mızrak D,Utkan G

更新日期：2015-04-07 00:00:00