Elastography-based screening for esophageal varices in patients with advanced chronic liver disease.

Abstract:

:Elastography-based liver stiffness measurement (LSM) is a non-invasive tool for estimating liver fibrosis but also provides an estimate for the severity of portal hypertension in patients with advanced chronic liver disease (ACLD). The presence of varices and especially of varices needing treatment (VNT) indicates distinct prognostic stages in patients with compensated ACLD (cACLD). The Baveno VI guidelines suggested a simple algorithm based on LSM < 20 kPa (by transient elastography, TE) and platelet count > 150 G/L for ruling-out VNT in patients with cACLD. These (and other) TE-based LSM cut-offs have been evaluated for VNT screening in different liver disease etiologies. Novel point shear-wave elastography (pSWE) and two-dimensional shear wave elastography (2D-SWE) methodologies for LSM have also been evaluated for their ability to screen for "any" varices and for VNT. Finally, the measurement of spleen stiffness (SSM) by elastography (mainly by pSWE and 2D-SWE) may represent another valuable screening tool for varices. Here, we summarize the current literature on elastography-based prediction of "any" varices and VNT. Finally, we have summarized the published LSM and SSM cut-offs in clinically useful scale cards.

journal_name

World J Gastroenterol

authors

Paternostro R,Reiberger T,Bucsics T

doi

10.3748/wjg.v25.i3.308

subject

Has Abstract

pub_date

2019-01-21 00:00:00

pages

308-329

issue

3

eissn

1007-9327

issn

2219-2840

journal_volume

25

pub_type

杂志文章,评审
  • Oleanolic acid and ursolic acid inhibit proliferation in transformed rat hepatic oval cells.

    abstract:AIM:To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA). METHODS:WB-F344 cells were continuously exposed to 7 x 10(-7) mol/L H2O2 for 21 d. Observations of cell morphology, colony formation rates, flow cyt...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i5.1348

    authors: Han YY,Xue XW,Shi ZM,Wang PY,Wu XR,Wang XJ

    更新日期:2014-02-07 00:00:00

  • Modulation of postoperative immune and inflammatory response by immune-enhancing enteral diet in gastrointestinal cancer patients.

    abstract:AIM:To evaluate if the administration of an enteral diet supplemented with glutamine, arginine and omega-3-fatty acids modulates inflammatory and immune responses after surgery. METHODS:A prospective randomized double-blind, clinical trial was performed. Forty-eight patients with gastrointestinal cancer were randomize...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3748/wjg.v7.i3.357

    authors: Wu GH,Zhang YW,Wu ZH

    更新日期:2001-06-01 00:00:00

  • Intra-abdominal drainage following pancreatic resection: A systematic review.

    abstract:AIM:To study all the aspects of drain management in pancreatic surgery. METHODS:We conducted a systematic review according to the PRISMA guidelines. We searched the Cochrane Central Registry of Controlled Trials, EMBASE, Web of Science, and PubMed (MEDLINE) for relevant articles on drain management in pancreatic surge...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i40.11458

    authors: Čečka F,Loveček M,Jon B,Skalický P,Šubrt Z,Neoral Č,Ferko A

    更新日期:2015-10-28 00:00:00

  • Incidence and clinical features of endoscopic ulcers developing after gastrectomy.

    abstract:AIM:To determine the precise incidence and clinical features of endoscopic ulcers following gastrectomy. METHODS:A consecutive series of patients who underwent endoscopic examination following gastrectomy between 2005 and 2010 was retrospectively analyzed. A total of 78 patients with endoscopic ulcers and 759 without ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i25.3260

    authors: Chung WC,Jeon EJ,Lee KM,Paik CN,Jung SH,Oh JH,Kim JH,Jun KH,Chin HM

    更新日期:2012-07-07 00:00:00

  • Exteriorized colon anastomosis for unprepared bowel: an alternative to routine colostomy.

    abstract:AIM:To see the possibility of avoiding routine colostomy in patients presenting with unprepared bowel. METHODS:The cohort is composed of 103 patients, of these, 86 patients presented as emergencies (self-inflected and iatrogenic colon injuries, stab wounds and blast injury of the colon, volvulus sigmoid, obstructing l...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i23.3215

    authors: Asfar SK,Al-Sayer HM,Juma TH

    更新日期:2007-06-21 00:00:00

  • Relationship between insulin A chain regions and insulin biological activities.

    abstract::AIM:To study the relationship between insulin A chain regions and insulin biological activities, we designed a series of insulin analogues with changes at A21, A12-18 of C terminal helical region and A8-10 located in the region of A6-A11 intra-chain disulphide bond.METHODS:Insulin A-chain analogues were prepared by st...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v6.i3.371

    authors: Yang SZ,Huang YD,Jie XF,Feng YM,Niu JY

    更新日期:2000-06-01 00:00:00

  • Practical approaches to effective management of intestinal radiation injury: benefit of resectional surgery.

    abstract:AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS:During a 7-year period we operated on 17 cases (5 male, 12 female) admitted to our surgical department with intestinal radiation injury (IRI). They were...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i35.4013

    authors: Perrakis N,Athanassiou E,Vamvakopoulou D,Kyriazi M,Kappos H,Vamvakopoulos NC,Nomikos I

    更新日期:2011-09-21 00:00:00

  • Psychosocial stress and liver disease status.

    abstract::"Psychosocial stress" is an increasingly common concept in the challenging and highly-demanding modern society of today. Organic response to stress implicates two major components of the stress system, namely the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. Stress is anamnestically reported ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.2980

    authors: Vere CC,Streba CT,Streba LM,Ionescu AG,Sima F

    更新日期:2009-06-28 00:00:00

  • Interaction or relationship between Helicobacter pylori and non-steroidal anti-inflammatory drugs in upper gastrointestinal diseases.

    abstract::According to a meta-analysis, H pylori and non-steroidal anti-inflammatory drugs (NSAID) independently and significantly increase the risk of gastroduodenal ulcer and ulcer bleeding. Their coincidence is frequent, demonstration of a possible relationship and consequent attitude is of important implications. But unfort...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v12.i24.3789

    authors: Ji KY,Hu FL

    更新日期:2006-06-28 00:00:00

  • Delayed internal pancreatic fistula with pancreatic pleural effusion postsplenectomy.

    abstract::The occurrence of pancreatic pleural effusion, secondary to an internal pancreatic fistula, is a rare clinical syndrome and diagnosis is often missed. The key to the diagnosis is a dramatically elevated pleural fluid amylase. This pancreatic pleural effusion is also called a pancreatic pleural fistula. It is character...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i35.4494

    authors: Jin SG,Chen ZY,Yan LN,Zeng Y

    更新日期:2010-09-21 00:00:00

  • Prevalence of Barrett's esophagus in patients with moderate to severe erosive esophagitis.

    abstract:AIM:To investigate the proportion of patients with moderate-severe erosive esophagitis (EE) who will have Barrett's esophagus (BE) after healing of inflammation. METHODS:Patients with EE of Los Angeles (LA) class B, C and D who underwent follow-up endoscopy documenting complete mucosal healing. RESULTS:A total of 86/...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.3518

    authors: Gilani N,Gerkin RD,Ramirez FC,Hakim S,Randolph AC

    更新日期:2008-06-14 00:00:00

  • Laparoscopic cholecystectomy for a left-sided gallbladder.

    abstract::Cholecystectomy is a common procedure. Abnormalities in the anatomy of the biliary system are common but an abnormal location of the gallbladder is much rarer. Despite frequent pre-operative imaging, the aberrant location of the gallbladder is commonly discovered at surgery. This article presents a case of a patient w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i35.5925

    authors: Iskandar ME,Radzio A,Krikhely M,Leitman IM

    更新日期:2013-09-21 00:00:00

  • When combination therapy isn't working: emerging therapies for the management of inflammatory bowel disease.

    abstract::Although antagonists of tumor necrosis factor have resulted in major therapeutic benefits in inflammatory bowel disease, the magnitude and durability of response are variable. Similar to previously available drugs such as 5-aminosalicylates and immunomodulators, the therapeutic effect is not universal leaving many peo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i5.1139

    authors: Krishnareddy S,Swaminath A

    更新日期:2014-02-07 00:00:00

  • A case of hypereosinophilic syndrome presenting with intractable gastric ulcers.

    abstract::We report a rare case of hypereosinophilic syndrome (HES) presenting with intractable gastric ulcers. A 71-year-old man was admitted with epigastric pain. Initial endoscopic findings revealed multiple, active gastric ulcers in the gastric antrum. He underwent Helicobacter pylori (H pylori) eradication therapy followed...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.6129

    authors: Park TY,Choi CH,Yang SY,Oh IS,Song ID,Lee HW,Kim HJ,Do JH,Chang SK,Cho AR,Cha YJ

    更新日期:2009-12-28 00:00:00

  • Intravenous vs intraperitoneal mesenchymal stem cells administration: what is the best route for treating experimental colitis?

    abstract:AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i48.18228

    authors: Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

    更新日期:2014-12-28 00:00:00

  • Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter?

    abstract::Hepatitis B virus (HBV) is the leading cause of liver disease and infects an estimated 240 million people worldwide. It is characterised by a high degree of genetic heterogeneity because of the use of a reverse transcriptase during viral replication. The ten genotypes (A-J) that have been described so far further segr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i24.7622

    authors: Zehender G,Ebranati E,Gabanelli E,Sorrentino C,Lo Presti A,Tanzi E,Ciccozzi M,Galli M

    更新日期:2014-06-28 00:00:00

  • Mesenteric vein thrombosis in a patient heterozygous for factor V Leiden and G20210A prothrombin genotypes.

    abstract::Mesenteric venous thrombosis (MVT) is a rare but life threatening form of bowel ischemia. It is implicated in 6%-9% of all cases of acute mesenteric ischemia. The proportion of patients with primary (or idiopathic) MVT varies from 0% to 49%, with a decrease in frequency secondary to more recent availability of newer i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i43.7813

    authors: Karmacharya P,Aryal MR,Donato A

    更新日期:2013-11-21 00:00:00

  • Relationship between the expression of human telomerase reverse transcriptase gene and cell cycle regulators in gastric cancer and its significance.

    abstract:AIM:To investigate the expression of human telomerase reverse transcriptase gene (hTRT) in gastric cancer (GC) and its relevance with cell cycle regulators including P16INK4, cyclin and P53. METHODS:In situ hybridization (ISH) for hTRT mRNA was performed in 53 cases of gastric cancer and adjacent cancerous tissues. Im...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i3.427

    authors: Shao JC,Wu JF,Wang DB,Qin R,Zhang H

    更新日期:2003-03-01 00:00:00

  • Prevalence of hepatitis G virus infection and homology of different viral strains in Southern China.

    abstract:AIM:To investigate the prevalence of hepatitis G virus (HGV) infection and to analyse the homology of different HGV strains in Southern China. METHODS:A total of 1993 sera from different groups in Guangdong, Hong Kong, and Yunnan were detected by reverse transcription polymerase chain reaction (RT-PCR). The nucleotide...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i6.1081

    authors: Li G,Ma HH,Lau GK,Leung YK,Yao CL,Chong YT,Tang WH,Yao JL

    更新日期:2002-12-01 00:00:00

  • Current understanding concerning intestinal stem cells.

    abstract::In mammals, the intestinal epithelium is a tissue that contains two distinct pools of stem cells: active intestinal stem cells and reserve intestinal stem cells. The former are located in the crypt basement membrane and are responsible for maintaining epithelial homeostasis under intact conditions, whereas the latter ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i31.7099

    authors: Cui S,Chang PY

    更新日期:2016-08-21 00:00:00

  • Exercise-provoked esophageal motility disorder in patients with recurrent chest pain.

    abstract:AIM:To investigate the relationship between exercise-provoked esophageal motility disorders and the prognosis for patients with chest pain. METHODS:The study involved 63 subjects with recurrent angina-like chest pain non-responsive to empirical therapy with proton pump inhibitor (PPI). In all, a coronary artery angiog...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i35.4428

    authors: Budzyński J

    更新日期:2010-09-21 00:00:00

  • Postprandial transduodenal bolus transport is regulated by complex peristaltic sequence.

    abstract:AIM:To study the relationship between the patterns of postprandial peristalsis and transduodenal bolus transport in healthy subjects. METHODS:Synchronous recording of chyme transport and peristaltic activity was performed during the fasting state and after administration of a test meal using a special catheter device ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i37.6008

    authors: Nguyen HN,Winograd R,Domingues GR,Lammert F

    更新日期:2006-10-07 00:00:00

  • NOB1 is essential for the survival of RKO colorectal cancer cells.

    abstract:AIM:To determine the role of NOB1, a regulator of cell survival in yeast, in human colorectal cancer cells. METHODS:Lentivirus-mediated small interfering RNA (siRNA) was used to inhibit NOB1 expression in RKO human colorectal cancer cells in vitro and in vivo in a mouse xenograft model. The in vitro and in vivo knockd...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i3.868

    authors: He XW,Feng T,Yin QL,Jian YW,Liu T

    更新日期:2015-01-21 00:00:00

  • Barrett's metaplasia: clinical implications.

    abstract::The incidence of Barrett's metaplasia (BM) as well as Barrett's adenocarcinoma (BA) has been increasing in western populations. The prognosis of BA is worse because individuals present at a late stage. Attempts have been made to intervene at early stage using surveillance programmes, although proof of efficacy of endo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v7.i4.563

    authors: Ishaq S,Jankowski JA

    更新日期:2001-08-01 00:00:00

  • Xenobiotics and loss of tolerance in primary biliary cholangitis.

    abstract::Data from genome wide association studies and geoepidemiological studies established that a combination of genetic predisposition and environmental stimulation is required for the loss of tolerance in primary biliary cholangitis (PBC). The serologic hallmark of PBC are the presence of high titer anti-mitochondrial aut...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i1.338

    authors: Wang J,Yang G,Dubrovsky AM,Choi J,Leung PS

    更新日期:2016-01-07 00:00:00

  • EUS-guided drainage is more successful in pancreatic pseudocysts compared with abscesses.

    abstract:AIM:To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage. METHODS:All patients referred for endoscopic drainage of a fluid collection were prospectively included. The outcome was recorded. RESULTS:Altogether 26 pseudocysts o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i4.499

    authors: Sadik R,Kalaitzakis E,Thune A,Hansen J,Jönson C

    更新日期:2011-01-28 00:00:00

  • Natural products and food components with anti-Helicobacter pylori activities.

    abstract::The bacterial pathogen Helicobacter pylori (H. pylori) colonizes in over half of the world's population. H. pylori that establishes life-long infection in the stomach is definitely associated with gastro-duodenal diseases and a wide variety of non-gastrointestinal tract conditions such as immune thrombocytopenia. Trip...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i27.8971

    authors: Takeuchi H,Trang VT,Morimoto N,Nishida Y,Matsumura Y,Sugiura T

    更新日期:2014-07-21 00:00:00

  • Plasma D (-)-lactate as a new marker for diagnosis of acute intestinal injury following ischemia-reperfusion.

    abstract:AIM:To observe the kinetics of D (-)-lactate alteration in both portal and systemic circulation systems, and its relationship with intestinal injury in rats subjected to acute intestinal ischemia-reperfusion. METHODS:Anesthetized rats underwent a 75-min superior mesenteric artery occlusion followed by a 6-h reperfusio...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v3.i4.225

    authors: Yao YM,Yu Y,Wu Y,Lu LR,Sheng ZY

    更新日期:1997-12-15 00:00:00

  • Primary sclerosing cholangitis--what is the difference between east and west?

    abstract::Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease characterized by inflammation and fibrotic obliteration of the hepatic biliary tree. It is commonly associated with inflammatory bowel disease (IBD). A number of complications can occur which require special consideration, the mo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.14.3974

    authors: Shorbagi A,Bayraktar Y

    更新日期:2008-07-07 00:00:00

  • Colonic manifestations of PTEN hamartoma tumor syndrome: case series and systematic review.

    abstract:AIM:To investigate our clinical experience with the colonic manifestations of phosphatase and tensin homolog on chromosome ten (PTEN) hamartoma tumor syndrome (PHTS) and to perform a systematic literature review regarding the same. METHODS:This study was approved by the appropriate institutional review board prior to ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i7.1833

    authors: Stanich PP,Pilarski R,Rock J,Frankel WL,El-Dika S,Meyer MM

    更新日期:2014-02-21 00:00:00