Intra-abdominal drainage following pancreatic resection: A systematic review.


AIM:To study all the aspects of drain management in pancreatic surgery. METHODS:We conducted a systematic review according to the PRISMA guidelines. We searched the Cochrane Central Registry of Controlled Trials, EMBASE, Web of Science, and PubMed (MEDLINE) for relevant articles on drain management in pancreatic surgery. The reference lists of relevant studies were screened to retrieve any further studies. We included all articles that reported clinical studies on human subjects with elective pancreatic resection and that compared various strategies of intra-abdominal drain management, such as drain vs no drain, selective drain use, early vs late drain extraction, and the use of different types of drains. RESULTS:A total of 19 studies concerned with drain management in pancreatic surgery involving 4194 patients were selected for this systematic review. We included studies analyzing the outcomes of pancreatic resection with and without intra-abdominal drains, studies comparing early vs late drain removal and studies analyzing different types of drains. The majority of the studies reporting equal or superior results for pancreatic resection without drains were retrospective and observational with significant selection bias. One recent randomized trial reported higher postoperative morbidity and mortality with routine omission of intra-abdominal drains. With respect to the timing of drain removal, all of the included studies reported superior results with early drain removal. Regarding the various types of drains, there is insufficient evidence to determine which type of drain is more suitable following pancreatic resection. CONCLUSION:The prophylactic use of drains remains controversial. When drains are used, early removal is recommended. Further trials comparing types of drains are ongoing.


World J Gastroenterol


Čečka F,Loveček M,Jon B,Skalický P,Šubrt Z,Neoral Č,Ferko A




Has Abstract


2015-10-28 00:00:00












  • Clinical usefulness of 18F-FDG PET/CT in the restaging of esophageal cancer after surgical resection and radiotherapy.

    abstract:AIM:To evaluate the clinical usefulness of (18)F-fluorodeoxyglucose positron emission and computed tomography ((18)F-FDG PET/CT) in restaging of esophageal cancer after surgical resection and radiotherapy. METHODS:Between January 2007 and Aug 2008, twenty histopathologically diagnosed esophageal cancer patients underw...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Sun L,Su XH,Guan YS,Pan WM,Luo ZM,Wei JH,Zhao L,Wu H

    更新日期:2009-04-21 00:00:00

  • Human endostatin gene transfer, either naked or with liposome, has the same inhibitory effect on growth of mouse liver tumor cells in vivo.

    abstract:AIM:To explore a safe and efficient strategy of tumor therapy using anti-angiogenetic agents. METHODS:Endostatin gene with a signal sequence of human IgGgamma chain was amplified by PCR and cloned into pVAX1 plasmid which was the only vector authorized by FDA in clinical trial to construct a recombinant plasmid named ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Ma CH,Zhang Y,Wang XY,Gao LF,Liu H,Guo C,Liu SX,Cao YL,Zhang LN,Sun WS

    更新日期:2004-10-01 00:00:00

  • Hepatic venous outflow obstruction: three similar syndromes.

    abstract::Our goal is to provide a detailed review of veno-occlusive disease (VOD), Budd-Chiari syndrome (BCS), and congestive hepatopathy (CH), all of which results in hepatic venous outflow obstruction. This is the first article in which all three syndromes have been reviewed, enabling the reader to compare the characteristic...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Bayraktar UD,Seren S,Bayraktar Y

    更新日期:2007-04-07 00:00:00

  • Seasonal variation in the onset of acute pancreatitis.

    abstract:AIM:A circannual variation in the onset of several acute diseases, mostly dealing with cardiovascular system, has been reported. The present study was to verify the possible existence of a seasonal variability in the onset of acute pancreatitis. METHODS:All patients consecutively admitted to the Hospital of Ferrara, I...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Gallerani M,Boari B,Salmi R,Manfredini R

    更新日期:2004-11-15 00:00:00

  • Restrictive vs liberal transfusion for upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials.

    abstract:AIM:To compare the outcome of upper gastrointestinal bleeding (UGIB) between patients receiving restrictive and liberal transfusion. METHODS:PubMed, EMBASE, and Cochrane Library databases were employed to identify all relevant randomized controlled trials regarding the outcome of UGIB after restrictive or liberal tran...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审


    authors: Wang J,Bao YX,Bai M,Zhang YG,Xu WD,Qi XS

    更新日期:2013-10-28 00:00:00

  • Nardostachys jatamansi extract protects against cytokine-induced beta-cell damage and streptozotocin-induced diabetes.

    abstract:AIM:To investigate the anti-diabetogenic mechanism of Nardostachys jatamansi extract (NJE). METHODS:Mice were injected with streptozotocin via a tail vein to induce diabetes. Rat insulinoma RINm5F cells and isolated rat islets were treated with interleukin-1beta and interferon-gamma to induce cytotoxicity. RESULTS:Tr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Song MY,Bae UJ,Lee BH,Kwon KB,Seo EA,Park SJ,Kim MS,Song HJ,Kwon KS,Park JW,Ryu DG,Park BH

    更新日期:2010-07-14 00:00:00

  • Human intestinal capillariasis in Thailand.

    abstract::Intestinal capillariasis caused by Capillaria philippinensis appeared first in the Philippines and subsequently in Thailand, Japan, Iran, Egypt and Taiwan; major outbreaks have occurred in the Philippines and Thailand. This article reviews the epidemiology, history and sources of C. philippinensis infection in Thailan...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Saichua P,Nithikathkul C,Kaewpitoon N

    更新日期:2008-01-28 00:00:00

  • Jaundice associated pruritis: a review of pathophysiology and treatment.

    abstract::To review the underlying pathophysiology and currently available treatments for pruritis associated with jaundice. English language literature was reviewed using MEDLINE, PubMed, EMBASE and for papers and trails addressing the pathophysiology and potential treatments for pruritis associated with jau...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Bassari R,Koea JB

    更新日期:2015-02-07 00:00:00

  • Upregulation of hypoxia inducible factor 1alpha mRNA is associated with elevated vascular endothelial growth factor expression and excessive angiogenesis and predicts a poor prognosis in gastric carcinoma.

    abstract:AIM:To investigate the implication of the hypoxia inducible factor HIF-1alpha mRNA in gastric carcinoma and its relation to the expression of vascular endothelial growth factor (VEGF) protein, tumor angiogenesis invasion/metastasis and the patient's survival. METHODS:In situ hybridization was used to examine expressio...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Ma J,Zhang L,Ru GQ,Zhao ZS,Xu WJ

    更新日期:2007-03-21 00:00:00

  • Hepatic resection for hepatocellular carcinoma in end-stage renal disease patients: two decades of experience at Chang Gung Memorial Hospital.

    abstract:AIM:Hepatocellular carcinoma (HCC) is a common disease in Taiwan. The prevalence of viral hepatitis infection and the subsequent development of HCC are well known to be higher in patients with end-stage renal disease (ESRD) requiring hemodialysis (HD) or peritoneal dialysis (PD) than among the general population. Howev...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Yeh CN,Lee WC,Chen MF

    更新日期:2005-04-14 00:00:00

  • Helicobacter pylori isolates from ethnic minority patients in Guangxi: resistance rates, mechanisms, and genotype.

    abstract:AIM:To investigate the rate of Helicobacter pylori (H. pylori) resistance to clarithromycin among ethnic minority patients in Guangxi, explore the underlying mechanisms, and analyze factors influencing genotype distribution of H. pylori isolates. METHODS:H. pylori strains were isolated, cultured and subjected to drug ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhao LJ,Huang YQ,Chen BP,Mo XQ,Huang ZS,Huang XF,Wei LD,Wei HY,Chen YH,Tang HY,Huang GR,Qin YC,Li XH,Wang LY

    更新日期:2014-04-28 00:00:00

  • Anti-Helicobacter pylori therapy significantly reduces Helicobacter pylori -induced gastric mucosal damage in Mongolian gerbils.

    abstract:AIM:To investigate the effectiveness of 4 d' anti-Helicobacter pylori therapy on the H pylori-infected Mongolian gerbils based on physiological and pathological changes. METHODS:We used 6-wk-old male gerbils orally inoculated with H pylori (ATCC43504, 2X10(8) CFU/mL). Seven weeks after H pylori inoculation, the animal...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Chang CC,Chen SH,Lien GS,Lee YJ,Lou HY,Hsieh CR,Fang CL,Pan S

    更新日期:2005-02-21 00:00:00

  • Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis.

    abstract:AIM:To assess the value of magnetic resonance elastography (MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis (AIH). METHODS:In this retrospective study, 36 patients (19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a te...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Wang J,Malik N,Yin M,Smyrk TC,Czaja AJ,Ehman RL,Venkatesh SK

    更新日期:2017-02-07 00:00:00

  • Prognostic value of KIT mutation in gastrointestinal stromal tumors.

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    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Liu XH,Bai CG,Xie Q,Feng F,Xu ZY,Ma DL

    更新日期:2005-07-07 00:00:00

  • Inhibitory effect of schisandrin B on gastric cancer cells in vitro.

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    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Liu XN,Zhang CY,Jin XD,Li YZ,Zheng XZ,Li L

    更新日期:2007-12-28 00:00:00

  • Is aggressive intravenous fluid resuscitation beneficial in acute pancreatitis? A meta-analysis of randomized control trials and cohort studies.

    abstract:BACKGROUND:There is conflincting evidence on the intravenous fluid (IVF) strategy for acute pancreatitis (AP). We perform a metaanalysis of the available evidence. AIM:To investigate if aggressive IVF therapy in AP patients is beneficial to decrease mortality and improve outcomes. METHODS:Metaanalysis of available ra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审


    authors: Gad MM,Simons-Linares CR

    更新日期:2020-03-14 00:00:00

  • Perivascular epithelioid cell tumour of the liver.

    abstract::Perivascular epithelioid cell tumour is not uncommon in the liver but seldom malignant. ...

    journal_title:World journal of gastroenterology

    pub_type: 评论,信件


    authors: Stenram U

    更新日期:2008-05-21 00:00:00

  • Microbial metabolites in non-alcoholic fatty liver disease.

    abstract::The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising exponentially worldwide. The spectrum of NAFLD includes non-alcoholic fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and even hepatocellular carcinoma. Evidence shows that microbial metabolites play pivotal roles in the onset and progr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Zhou D,Fan JG

    更新日期:2019-05-07 00:00:00

  • Pancreatic necrosis and severity are independent risk factors for pancreatic endocrine insufficiency after acute pancreatitis: A long-term follow-up study.

    abstract:BACKGROUND:Pancreatic endocrine insufficiency after acute pancreatitis (AP) has drawn increasing attention in recent years. AIM:To assess the impact of risk factors on the development of pancreatic endocrine insufficiency after AP. METHODS:This retrospective observational long-term follow-up study was conducted in a ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Yu BJ,Li NS,He WH,He C,Wan JH,Zhu Y,Lu NH

    更新日期:2020-06-21 00:00:00

  • KRAS mutation testing in metastatic colorectal cancer.

    abstract::The KRAS oncogene is mutated in approximately 35%-45% of colorectal cancers, and KRAS mutational status testing has been highlighted in recent years. The most frequent mutations in this gene, point substitutions in codons 12 and 13, were validated as negative predictors of response to anti-epidermal growth factor rece...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Tan C,Du X

    更新日期:2012-10-07 00:00:00

  • Fixation methods for electron microscopy of human and other liver.

    abstract::For an electron microscopic study of the liver, expertise and complicated, time-consuming processing of hepatic tissues and cells is needed. The interpretation of electron microscopy (EM) images requires knowledge of the liver fine structure and experience with the numerous artifacts in fixation, embedding, sectioning...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Wisse E,Braet F,Duimel H,Vreuls C,Koek G,Olde Damink SW,van den Broek MA,De Geest B,Dejong CH,Tateno C,Frederik P

    更新日期:2010-06-21 00:00:00

  • Prediction of risk factors for lymph node metastasis in early gastric cancer.

    abstract:AIM:To explore risk factors for lymph node metastases in early gastric cancer (EGC) and to confirm the appropriate range of lymph node dissection. METHODS:A total of 202 patients with EGC who underwent curative gastrectomy with lymphadenectomy in the Department of Surgery, Xinhua Hospital and Ruijin Hospital of Shangh...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Ren G,Cai R,Zhang WJ,Ou JM,Jin YN,Li WH

    更新日期:2013-05-28 00:00:00

  • Efficacy and safety of gemcitabine-based chemotherapies in biliary tract cancer: a meta-analysis.

    abstract:AIM:To investigate the efficacy and safety of gemcitabine (Gem)-based combination chemotherapies for the treatment of advanced biliary tract cancer. METHODS:Clinical trials were identified by searching scientific literature databases (PubMed, EMBASE and the Cochrane Library) for studies published between 1975 and 2013...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审


    authors: Liu H,Zhang QD,Li ZH,Zhang QQ,Lu LG

    更新日期:2014-12-21 00:00:00

  • Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier.

    abstract::The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin's lymphoma (NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Lee MH,Lin YC,Cheng HT,Chuang WY,Huang HC,Kao HW

    更新日期:2015-12-07 00:00:00

  • Risk factors for intrahepatic cholangiocarcinoma: a case-control study in China.

    abstract:AIM:To carry out a hospital-based case-control study to investigate risk factors for intrahepatic cholangiocarcinoma (ICC) in China. METHODS:A total of 312 ICC cases and 438 matched controls were included in the study. The presence of diabetes mellitus, hypertension, hepatolithiasis, primary sclerosing cholangitis, li...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhou YM,Yin ZF,Yang JM,Li B,Shao WY,Xu F,Wang YL,Li DQ

    更新日期:2008-01-28 00:00:00

  • Accuracy of combined PET/CT in image-guided interventions of liver lesions: an ex-vivo study.

    abstract:AIM:Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS:Thirty lesions each of hyperdense, isodense and hypodense attenua...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Veit P,Kuehle C,Beyer T,Kuehl H,Bockisch A,Antoch G

    更新日期:2006-04-21 00:00:00

  • Chinese guidelines on the management of liver cirrhosis (abbreviated version).

    abstract::Based on reviews of the literature and experts' consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice. In addition to what has been covered in previously published guidelines on the management of cirrhosis complicatio...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Xu XY,Ding HG,Li WG,Xu JH,Han Y,Jia JD,Wei L,Duan ZP,Ling-Hu EQ,Zhuang H

    更新日期:2020-12-07 00:00:00

  • An implantable rat liver tumor model for experimental transarterial chemoembolization therapy and its imaging features.

    abstract:AIM:To establish an ideal implantable rat liver tumor model for interventional therapy study and examine its angiographic signs and MRI, CT features before and after embolization. METHODS:Forty male Wistar rats were implanted with Walker-256 tumor in the left lateral lobe of liver. Digital subtraction angiography (DSA...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Li X,Zheng CS,Feng GS,Zhuo CK,Zhao JG,Liu X

    更新日期:2002-12-01 00:00:00

  • Endoscopic management of chronic radiation proctitis.

    abstract::Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy. Although many cases resolve spontaneously, some lead to chronic symptoms including diarrhea, tenesmus, urgency and persistent rectal bleeding with iron deficiency anemia requiring blood transfusions. Treatments for chronic radiat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Rustagi T,Mashimo H

    更新日期:2011-11-07 00:00:00

  • Does flexible small-diameter colonoscope reduce insertion pain during colonoscopy?

    abstract::AIM:It is well known that colonoscopy can be difficult due to abdominal pain induced during colonoscope insertion, if sedative agents are not given. Recently, an extra-flexible, small-diameter colonoscope (CF-SV, Olympus Inc.Japan) was developed in order to improve safety and comfort. The aim of this study was to acce...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Han Y,Uno Y,Munakata A

    更新日期:2000-10-01 00:00:00