EUS-guided drainage is more successful in pancreatic pseudocysts compared with abscesses.

abstract：AIM:To investigate the molecular mechanism and functional consequences of heme oxygenase-1 (HO-1) activation by lansoprazole in endothelial cells and macrophages. METHODS:Expression of HO-1 mRNA was analyzed by Northern blotting. Western blotting was used to determine the HO-1 and ferritin protein levels. NADPH-depend...

journal_title：World journal of gastroenterology

authors： Schulz-Geske S,Erdmann K,Wong RJ,Stevenson DK,Schröder H,Grosser N

更新日期：2009-09-21 00:00:00

abstract：AIM:To determine serum vitamin D levels and colonic vitamin D receptor (VDR) expression in inflammatory bowel disease (IBD) and non-IBD patients and correlate these with histopathology. METHODS:Puerto Rican IBD (n = 10) and non-IBD (n = 10) patients ≥ 21 years old scheduled for colonoscopy were recruited. Each patient...

journal_title：World journal of gastroenterology

authors： Abreu-Delgado Y,Isidro RA,Torres EA,González A,Cruz ML,Isidro AA,González-Keelan CI,Medero P,Appleyard CB

更新日期：2016-04-07 00:00:00

abstract：AIM:Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genes are involved in the metabolism of a wide range of carcinogens, but deletions of the genes are commonly found in the population. The present study was undertaken to evaluate the association between GSTM1 and GSTT1 gene polymorphisms and hepatocellular ...

journal_title：World journal of gastroenterology

authors： Deng ZL,Wei YP,Ma Y

更新日期：2005-01-14 00:00:00

abstract：:Acute pancreatitis (AP) is an acute inflammatory disease of the exocrine pancreas. In Japan, nationwide epidemiological surveys have been conducted every 4 to 5 years by the Research Committee of Intractable Pancreatic Diseases, under the support of the Ministry of Health, Labour, and Welfare of Japan. We reviewed the...

journal_title：World journal of gastroenterology

authors： Hamada S,Masamune A,Shimosegawa T

更新日期：2016-07-28 00:00:00

abstract：AIM:To investigate the inhibitory effects of sinomenine (SIN) combined with 5-fluorouracil (5-FU) on esophageal carcinoma in vitro and in vivo. METHODS:Esophageal carcinoma (Eca-109) cells were cultured in DMEM. The single or combined growth inhibition effects of SIN and 5-FU on the Eca-109 cells were examined by meas...

journal_title：World journal of gastroenterology

authors： Wang J,Yang ZR,Dong WG,Zhang JX,Guo XF,Song J,Qiu S

更新日期：2013-12-07 00:00:00

abstract：:Sorafenib is the current standard treatment for advanced hepatocellular carcinoma (HCC), but its efficacy is modest with low response rates and short response duration. Predictive biomarkers for sorafenib efficacy are necessary. However, efforts to determine biomarkers for sorafenib have led only to potential candidat...

journal_title：World journal of gastroenterology

authors： Shao YY,Hsu CH,Cheng AL

更新日期：2015-09-28 00:00:00

abstract：:During the last decades, further knowledge of hepatocellular carcinoma (HCC) molecular mechanisms has led to development of effective systemic treatments including tyrosine kinase inhibitors (TKIs) and immunotherapy. In this review, we describe first and second line systemic treatment options for advanced HCC. Several...

journal_title：World journal of gastroenterology

authors： Piñero F,Silva M,Iavarone M

更新日期：2020-04-28 00:00:00

abstract：AIM:To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As₂O₃); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2. METHODS:Twenty patients with gastrointestin...

journal_title：World journal of gastroenterology

authors： Ma ZB,Xu HY,Jiang M,Yang YL,Liu LX,Li YH

更新日期：2014-05-14 00:00:00

abstract：:To present problems that might severely impact the conclusions drawn by the authors of an article on antioxidant treatment in chronic pancreatitis (World J Gastroenterol 2010; 16: 4066-4071). We analyzed and discussed this paper by Shah et al, and found that promising as it is, this study has some methodological short...

journal_title：World journal of gastroenterology

authors： Stefaniak T,Vingerhoets A,Sledzinski Z

更新日期：2012-05-21 00:00:00

abstract：:The use of thiopurines as immunosuppression for the treatment of refractory or chronic active inflammatory bowel disease is established for both Crohn's disease and ulcerative colitis. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine, 6-mercaptopurine and thioguanine. We wi...

journal_title：World journal of gastroenterology

authors： Frei P,Biedermann L,Nielsen OH,Rogler G

更新日期：2013-02-21 00:00:00

abstract：AIM:To highlight magnetic resonance enterography (MRE) for diagnosis of patients with refractory iron deficiency anemia and normal endoscopy results. METHODS:Fifty-three patients diagnosed with iron deficiency anemia refractory to treatment and normal gastroscopy and colonoscopy results were admitted to this prospecti...

journal_title：World journal of gastroenterology

authors： Cengic I,Tureli D,Aydin H,Bugdayci O,Imeryuz N,Tuney D

更新日期：2014-10-14 00:00:00

abstract：:Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-densit...

journal_title：World journal of gastroenterology

authors： Temel RE,Brown JM

更新日期：2010-12-21 00:00:00

abstract：:Inflammatory bowel diseases (IBDs) are characterized by a chronic course with an alternation of relapses and remissions. Questions about prognosis are important for the patient who wants to know how the disease will affect his/her life and also for clinicians to make management decisions. Correct selection of the pati...

journal_title：World journal of gastroenterology

authors： Modesto I,Perricone G,Orlando A,Cottone M

更新日期：2012-08-07 00:00:00

abstract：AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

journal_title：World journal of gastroenterology

authors： Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

更新日期：2006-01-14 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients' quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant...

journal_title：World journal of gastroenterology

authors： Lazaraki G,Chatzimavroudis G,Katsinelos P

更新日期：2014-07-21 00:00:00

abstract：:High-throughput short-read sequencing of exomes and whole cancer genomes in multiple human hepatocellular carcinoma (HCC) cohorts confirmed previously identified frequently mutated somatic genes, such as TP53, CTNNB1 and AXIN1, and identified several novel genes with moderate mutation frequencies, including ARID1A, AR...

journal_title：World journal of gastroenterology

authors： Gu DL,Chen YH,Shih JH,Lin CH,Jou YS,Chen CF

更新日期：2013-12-21 00:00:00

abstract：AIM:To determine whether IFN-alpha is the agent that turns a slightly effective treatment (radiochemotherapy) into a potent therapy, we tested IFN-alpha for its synergistic properties. METHODS:Eight pancreatic carcinoma cell lines were treated with the single agents and combinations of these. The role of IFN-alpha reg...

journal_title：World journal of gastroenterology

authors： Ma JH,Patrut E,Schmidt J,Knaebel HP,Büchler MW,Märten A

更新日期：2005-03-14 00:00:00

abstract：AIM:To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice. METHODS:Balb/c mice were fed with the fermented milk for 7 d after inducing gastritis with acetyl-salicylic acid (ASA, 400 m...

journal_title：World journal of gastroenterology

authors： Rodríguez C,Medici M,Mozzi F,Font de Valdez G

更新日期：2010-04-07 00:00:00

abstract：AIM:To study immune response induced by foreign plasmid DNA after oral administration in mice. METHODS:Mice were orally administered with 200 mug of plasmid pcDNA3 once and spleen was isolated 4 h and 18 h after administration. Total RNA was extracted from spleen and gene expression profile of BALB/c mice spleen was a...

journal_title：World journal of gastroenterology

authors： Liu JW,Cheng J

更新日期：2007-07-28 00:00:00

abstract：AIM:To investigate the changes that occur in E-cadherin expression during the process of metastasis in colorectal cancer. METHODS:E-cadherin expression was detected by immunohistochemistry and two indices of expression were calculated which reflected the level of expression and the locations (membrane and cytoplasm). ...

journal_title：World journal of gastroenterology

authors： Elzagheid A,Algars A,Bendardaf R,Lamlum H,Ristamaki R,Collan Y,Syrjanen K,Pyrhonen S

更新日期：2006-07-21 00:00:00

abstract：:Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the world. This debilitating bowel disease can start in early childhood and continue into late adulthood. Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease....

journal_title：World journal of gastroenterology

authors： Naser SA,Sagramsingh SR,Naser AS,Thanigachalam S

更新日期：2014-06-21 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis and advanced hepatic fibrosis. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked w...

journal_title：World journal of gastroenterology

authors： Fotbolcu H,Zorlu E

更新日期：2016-04-28 00:00:00

abstract：AIM:To investigate in patients with functional dyspepsia (FD) after an every-day meal whether (1) gastrointestinal (GI) and extra-GI symptoms had any relation with the degree of antral volume, (2) the onset of postprandial symptoms was associated with, and may predict, delayed gastric emptying. METHODS:In 94 symptomat...

journal_title：World journal of gastroenterology

authors： Pallotta N,Pezzotti P,Corazziari E

更新日期：2006-11-21 00:00:00

abstract：AIM:To assess the outcomes of ampulla dilation with different sized balloons to remove common bile duct (CBD) stones. METHODS:Patients (n = 208) were divided into five groups based on the largest CBD stone size of < 5, 6-8, 8-12, 12-14, and > 14 mm. Patients underwent limited endoscopic sphincterotomy (EST) alone or l...

journal_title：World journal of gastroenterology

authors： Li NP,Liu JQ,Zhou ZQ,Ji TY,Cai XY,Zhu QY

更新日期：2013-02-14 00:00:00

abstract：AIM:To investigate the expression of the transforming growth factor beta 1(TGF-beta 1) mRNA in different stages of alcoholic liver disease (ALD) and its clinical value. METHODS:One hundred and seven male alcoholics were grouped by clinical findings into four groups: alcohol abusers without liver impairment (n =22), al...

journal_title：World journal of gastroenterology

authors： Chen WX,Li YM,Yu CH,Cai WM,Zheng M,Chen F

更新日期：2002-04-01 00:00:00

abstract：:A number of alterations have been found within the gut microbial profile of patients with inflammatory bowel diseases when compared with the healthy population; however, it is unclear whether such dysbiosis is the cause or simply the consequence of the disease state. In ulcerative colitis, the environment seems to pla...

journal_title：World journal of gastroenterology

authors： Sorrentino D

更新日期：2017-10-07 00:00:00

abstract：AIM:To evaluate the safety of Curcuma aromatica oil gelatin microspheres (CAO-GMS) infused via hepatic artery against primary liver cancer. METHODS:The safety of CAO-GMS was evaluated in view of its acute toxicity in rats, long-term toxicity in Beagle dogs and general pharmacology in rats and mongrel dogs. RESULTS:Th...

journal_title：World journal of gastroenterology

authors： Deng SG,Wu ZF,Li WY,Yang ZG,Chang G,Meng FZ,Mo LL

更新日期：2004-09-15 00:00:00

abstract：AIM:To investigate the incidence, characteristics, and risk factors for hepatocellular carcinoma (HCC) in Chinese patients with primary biliary cirrhosis (PBC). METHODS:We reviewed the data of 52 PBC-associated HCC patients treated at Beijing 302 Hospital from January 2002 to December 2013 and analyzed its incidence a...

journal_title：World journal of gastroenterology

authors： Zhang XX,Wang LF,Jin L,Li YY,Hao SL,Shi YC,Zeng QL,Li ZW,Zhang Z,Lau GK,Wang FS

更新日期：2015-03-28 00:00:00

abstract：AIM:To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis. METHODS:Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 ...

journal_title：World journal of gastroenterology

authors： Letoha T,Fehér LZ,Pecze L,Somlai C,Varga I,Kaszaki J,Tóth G,Vizler C,Tiszlavicz L,Takács T

更新日期：2007-09-07 00:00:00

abstract：:Based on reviews of the literature and experts' consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice. In addition to what has been covered in previously published guidelines on the management of cirrhosis complicatio...

journal_title：World journal of gastroenterology

authors： Xu XY,Ding HG,Li WG,Xu JH,Han Y,Jia JD,Wei L,Duan ZP,Ling-Hu EQ,Zhuang H

更新日期：2020-12-07 00:00:00