Methodology for high-quality studies on course and prognosis of inflammatory bowel disease.

abstract：AIM:To investigate the expression of leukemia related protein 16 (LRP16), and the possible relationship between LRP16 expression and clinicopathological indices in 336 gastric carcinoma patients. METHODS:Immunohistochemistry was used to detect LRP16 expression in 336 cases of paraffin-embedded gastric carcinoma tissue...

journal_title：World journal of gastroenterology

authors： Li YZ,Zhao P,Han WD

更新日期：2009-10-14 00:00:00

abstract：AIM:To analyze small intestinal bacterial overgrowth in school-aged children and the relationship between hydrogen and methane production in breath tests. METHODS:This transversal study included 85 children residing in a slum and 43 children from a private school, all aged between 6 and 10 years, in Osasco, Brazil. Fo...

journal_title：World journal of gastroenterology

authors： Mello CS,Tahan S,Melli LC,Rodrigues MS,de Mello RM,Scaletsky IC,de Morais MB

更新日期：2012-11-07 00:00:00

abstract：AIM:To investigate the expression and clinical relevance of inhibitor of differentiation (ID) proteins in biliary tract cancer. METHODS:ID protein expression was analyzed in 129 samples from patients with advanced biliary tract cancer (BTC) (45 extrahepatic, 50 intrahepatic, and 34 gallbladder cancers), compared to no...

journal_title：World journal of gastroenterology

authors： Harder J,Müller MJ,Fuchs M,Gumpp V,Schmitt-Graeff A,Fischer R,Frank M,Opitz O,Hasskarl J

更新日期：2013-12-28 00:00:00

abstract：AIM:To compare ghrelin levels in plasma and gastric mucosa before and after Helicobacter pylori (H. pylori) treatment in children with H. pylori-associated functional dyspepsia. METHODS:Children with H. pylori-associated functional dyspepsia were enrolled in this study. H. pylori infection was confirmed by positive ba...

journal_title：World journal of gastroenterology

authors： Deng ZH,Chu B,Xu YZ,Zhang B,Jiang LR

更新日期：2012-09-28 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：:Constitutive activation of the insulin-like growth factor (IGF)-signaling axis is frequently observed in human hepatocellular carcinoma (HCC). Especially the overexpression of the fetal growth factor IGF-II, IGF-I receptor (IGF-IR), and cytoplasmic downstream effectors such as insulin-receptor substrates (IRS) contrib...

journal_title：World journal of gastroenterology

authors： Breuhahn K,Schirmacher P

更新日期：2008-03-21 00:00:00

abstract：:Hepatitis C virus (HCV) infection is estimated to affect 130-150 million people globally which corresponds to 2%-3% of the total world population. It remains the leading indication for liver transplant worldwide and has been demonstrated to negatively impact both patient and graft survival following non-hepatic organ ...

journal_title：World journal of gastroenterology

authors： Belga S,Doucette KE

更新日期：2016-01-28 00:00:00

abstract：AIM:To assess the etiology of chronic liver diseases (CLD) from 1998 to 2014 at the outpatient clinic of Gastroenterology of the main hospital in Northwest of Italy among those dedicated to hepatology. METHODS:A random sample of charts of patients referred to for increased liver enzymes between January 1998 and Decemb...

journal_title：World journal of gastroenterology

authors： Saracco GM,Evangelista A,Fagoonee S,Ciccone G,Bugianesi E,Caviglia GP,Abate ML,Rizzetto M,Pellicano R,Smedile A

更新日期：2016-09-28 00:00:00

abstract：AIM:To transfer hepatitis E virus (HEV) ORF2 partial gene to tomato plants, to investigate its expression in transformants and the immunoactivity of expression products, and to explore the feasibility of developing a new type of plant-derived HEV oral vaccine. METHODS:Plant binary expression vector p1301E2, carrying a...

journal_title：World journal of gastroenterology

authors： Ma Y,Lin SQ,Gao Y,Li M,Luo WX,Zhang J,Xia NS

更新日期：2003-10-01 00:00:00

abstract：AIM:To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS:The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment an...

journal_title：World journal of gastroenterology

authors： Zhu JS,Wang L,Cheng GQ,Li Q,Zhu ZM,Zhu L

更新日期：2005-12-21 00:00:00

abstract：AIM:To examine the prevalence and prognostic significance of C-kit gene mutation and analysis the correlation of C-kit gene mutation and the clinicalpathologic parameters of GISTs. METHODS:Eighty-two GISTs were studied for the mutation of C-kit gene by PCR-SSCP, DNA sequence. Statistical comparison were used to analys...

journal_title：World journal of gastroenterology

authors： Liu XH,Bai CG,Xie Q,Feng F,Xu ZY,Ma DL

更新日期：2005-07-07 00:00:00

abstract：AIM:To investigate the prognostic significance of perioperative leukopenia in patients with resected gastric cancer. METHODS:A total of 614 eligible gastric cancer patients who underwent curative D2 gastrectomy and adjuvant chemotherapy were enrolled in this study. The relationship between pre- and postoperative hemat...

journal_title：World journal of gastroenterology

authors： Chen XF,Qian J,Pei D,Zhou C,Røe OD,Zhu F,He SH,Qian YY,Zhou Y,Xu J,Xu J,Li X,Ping GQ,Liu YQ,Wang P,Guo RH,Shu YQ

更新日期：2016-03-07 00:00:00

abstract：:Primary liver cancer is amongst the commonest tumors worldwide, particularly in parts of the developing world, and is increasing in incidence. Over the past three decades, surgical hepatic resection has evolved from a high risk, resource intensive procedure with limited application, to a safe and commonly performed op...

journal_title：World journal of gastroenterology

authors： Tsim NC,Frampton AE,Habib NA,Jiao LR

更新日期：2010-02-28 00:00:00

abstract：AIM:To evaluate the accuracy of spot urinary Na/K and Na/creatinine (Cr) ratios as an alternative to 24-h urinary sodium in monitoring dietary compliance in patients with liver cirrhosis and ascites treated with diuretics. METHODS:The study was carried on 40 patients with liver cirrhosis and ascites treated with diure...

journal_title：World journal of gastroenterology

authors： El-Bokl MA,Senousy BE,El-Karmouty KZ,Mohammed Iel K,Mohammed SM,Shabana SS,Shalaby H

更新日期：2009-08-07 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：AIM:To retrospectively evaluate the vaccination-induced anti-HBs seroconversion rates in treatment-naive and treatment-experienced chronic hepatitis C (CHC) patients. Also to prospectively evaluate the seroconversion rates in CHC patients during pegylated interferon (PEG) plus ribavirin (RIB) treatment. METHODS:Sevent...

journal_title：World journal of gastroenterology

authors： Elefsiniotis IS,Vezali E,Kamposioras K,Pantazis KD,Tontorova R,Ketikoglou I,Moulakakis A,Saroglou G

更新日期：2006-07-21 00:00:00

abstract：AIM:To prospectively investigate the detection rate of laterally spreading tumors (LSTs) of the colorectum by computed tomography (CT) colonography (CTC). METHODS:Patients with LSTs measuring ≥ 20 mm detected during colonoscopy were prospectively enrolled in the study. All patients underwent colonoscopy and subsequent...

journal_title：World journal of gastroenterology

authors： Togashi K,Utano K,Kijima S,Sato Y,Horie H,Sunada K,Lefor AT,Sugimoto H,Yasuda Y

更新日期：2014-12-14 00:00:00

abstract：AIM:To investigate the prevalence of celiac disease (CD) in adult patients referred to an open access gastroenterology clinic in the south of Italy and submitted to esophago-gastro-duodenoscopy (EGD) for evaluation of refractory functional dyspepsia. METHODS:Seven hundred and twenty six consecutive dyspeptic patients ...

journal_title：World journal of gastroenterology

authors： Giangreco E,D'agate C,Barbera C,Puzzo L,Aprile G,Naso P,Bonanno G,Russo FP,Nicoletti A,Incarbone S,Trama G,Russo A

更新日期：2008-12-07 00:00:00

abstract：AIM:To study the beneficial effects of triterpene alpha,beta-amyrin and the underlying mechanisms in an experimental pancreatitis model. METHODS:Acute pancreatitis was induced in five groups of rats (n = 8) by L-arginine (2 x 2.5 g/kg, intraperitoneal, 1 h apart) and 1 h later, they received a single oral dose of alph...

journal_title：World journal of gastroenterology

authors： Melo CM,Carvalho KM,Neves JC,Morais TC,Rao VS,Santos FA,Brito GA,Chaves MH

更新日期：2010-09-14 00:00:00

abstract：AIM:To investigate the effect of Boschniakia rossica (BR), oxymatrine (OM) and interferon-alpha (IFN-alpha) 1b on the therapy of rat liver fibrosis and its mechanism. METHODS:By establishing a rat model of pig serum-induced liver fibrosis, liver/weight index and serum alanine transaminase (ALT) were observed to invest...

journal_title：World journal of gastroenterology

authors： Wu CS,Piao XX,Piao DM,Jin YR,Li CH

更新日期：2005-01-07 00:00:00

abstract：AIM:To evaluate the association of glutathione S-transferase mu (GSTM1) and glutathione S-transferase theta (GSTT1) null genotypes with the risk of gastric cancer (GC) and colorectal cancer (CRC) in a South Korean population. METHODS:We conducted a population-based, large-scale case-control study including 2213 GCs, 1...

journal_title：World journal of gastroenterology

authors： Piao JM,Shin MH,Kweon SS,Kim HN,Choi JS,Bae WK,Shim HJ,Kim HR,Park YK,Choi YD,Kim SH

更新日期：2009-12-07 00:00:00

abstract：:Schwannomas are mesenchymal tumors originating from Schwann cells in peripheral nerve sheaths. Although the tumor can be located in any part of the human body, the most common locations are the head, neck, trunk and extremities. Pancreatic schwannomas are rare. To our knowledge, only 64 cases of pancreatic schwannoma ...

journal_title：World journal of gastroenterology

authors： Xu SY,Sun K,Owusu-Ansah KG,Xie HY,Zhou L,Zheng SS,Wang WL

更新日期：2016-10-07 00:00:00

abstract：:Statins are a class of molecules that inhibit HMG CoA reductase. They are usually prescribed as a lipid lowering medication. However, there is accumulating evidence that statins have multiple secondary effects both related and unrelated to their lipid-lowering effect. This narrative review of the literature aims to pr...

journal_title：World journal of gastroenterology

authors： Janicko M,Drazilova S,Pella D,Fedacko J,Jarcuska P

更新日期：2016-07-21 00:00:00

abstract：:Wireless capsule endoscope (WCE) for the investigation of the small bowel is an approved technique both in adults and children (more than 10 years old). The present review provides data on the indications, diagnostic yield, adverse events and limitations of the WCE technique in children and tries to predict the future...

journal_title：World journal of gastroenterology

authors： Shamir R,Eliakim R

更新日期：2008-07-14 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, and three cases have been previously described in India in which GBS was associated with acute hepatitis E. A molecular mimicry mechanism is s...

journal_title：World journal of gastroenterology

authors： Loly JP,Rikir E,Seivert M,Legros E,Defrance P,Belaiche J,Moonen G,Delwaide J

更新日期：2009-04-07 00:00:00

abstract：AIM:To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS:Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM....

journal_title：World journal of gastroenterology

authors： Sung CM,Hsu CM,Hsu JT,Yeh TS,Lin CJ,Chen TC,Su MY,Chiu CT

更新日期：2010-11-07 00:00:00

abstract：:AIM:To investigate the specific pathogenesis of O-polysaccharide (O-PS) which is on the outer membrane of lipopolysaccharides (LPS) from Shigella flexneri.METHODS:The O-PS was isolated and purified from Shigella flexneri 5 M90T by enzymatic hydrolysis and gel chromatography. Effects of O-PS were observed by in vitro e...

journal_title：World journal of gastroenterology

authors： Zhong QP

更新日期：1999-06-01 00:00:00

abstract：:A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99...

journal_title：World journal of gastroenterology

authors： Sano S,Yamagami K,Tanaka A,Nishio M,Nakamura T,Kubo Y,Inoue T,Ueda W,Okawa K,Yoshioka K

更新日期：2008-10-21 00:00:00

abstract：:Intestinal lymphangiectasia, characterized by dilatation of intestinal lacteals, is rare. The major treatment for primary intestinal lymphangiectasia is dietary modification. Surgery to relieve symptoms and to clarify the etiology should be considered when medical treatment failed. This article reports a 49-year-old w...

journal_title：World journal of gastroenterology

authors： Chen CP,Chao Y,Li CP,Lo WC,Wu CW,Tsay SH,Lee RC,Chang FY

更新日期：2003-12-01 00:00:00

abstract：AIM:To study the effects of Changtai granules (CTG), a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. METHODS:Healthy adult Sprague-Dawley (SD) rats of both sexes, weighing 250-300 g, were employed in the present study. The rat colitis models were induced by 2,...

journal_title：World journal of gastroenterology

authors： Cao YB,Zhang JD,Diao YY,Yan L,Wang DJ,Jia XM,Gao PH,Cheng MH,Xu Z,Wang Y,Jiang YY

更新日期：2005-06-21 00:00:00