Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population.

abstract：AIM:To observe the therapeutic effects of dexamethasone on rats with severe acute pancreatitis (SAP) and investigate the influences of dexamethasone on the inflammatory mediators and NF-kappaB expression in multiple organs of SAP rats as well as the mechanisms involved. METHODS:Ninety Sprague-Dawley (SD) rats with SAP...

journal_title：World journal of gastroenterology

authors： Zhang XP,Zhang L,Chen LJ,Cheng QH,Wang JM,Cai W,Shen HP,Cai J

更新日期：2007-01-28 00:00:00

abstract：:Perivascular epithelioid cell tumour is not uncommon in the liver but seldom malignant. ...

journal_title：World journal of gastroenterology

authors： Stenram U

更新日期：2008-05-21 00:00:00

abstract：AIM:To report the outcome of Chinese patents with non-cystic adenocarcinoma in pancreatic body and tail (NCAPBT) after resection and to discuss its surgical strategy. METHODS:Resection of NCAPBT was performed in eight Chinese patients with complete clinical-pathological data in our hospital from January 2000 to May 20...

journal_title：World journal of gastroenterology

authors： Yan HC,Wu YL,Chen LR,Gao SL

更新日期：2006-09-21 00:00:00

abstract：AIM:To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS:Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM....

journal_title：World journal of gastroenterology

authors： Sung CM,Hsu CM,Hsu JT,Yeh TS,Lin CJ,Chen TC,Su MY,Chiu CT

更新日期：2010-11-07 00:00:00

abstract：AIM:To assess the utility of contrast-enhanced ultrasonography (CEUS) with a second-generation contrast medium in the differential diagnosis between mass-forming pancreatitis and pancreatic carcinoma. METHODS:From our radio-pathology database, we retrieved all the patients affected by mass-forming pancreatitis or panc...

journal_title：World journal of gastroenterology

authors： D'Onofrio M,Zamboni G,Tognolini A,Malago R,Faccioli N,Frulloni L,Pozzi Mucelli R

更新日期：2006-07-14 00:00:00

abstract：AIM:To study the anti-hepatofibrosis mechanism of Bie Jia Jian oral liquid (BOL). METHODS:The model was induced by subcutaneous injection of CCl(4). BOL was administered and the change of serum hyaluronic acid (HA) and laminin (LN) was observed and the degeneration of liver cells and the degree of fibre hyperplasia an...

journal_title：World journal of gastroenterology

authors： Yao L,Yao ZM,Yu T

更新日期：2001-12-01 00:00:00

abstract：AIM:Because of a major resistance to chemotherapy, prognosis of hepatocellular carcinoma (HCC) is still poor. New treatments are required and gene therapy may be an option. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in multiple malignant tumors, and using adenoviral vectors has sh...

journal_title：World journal of gastroenterology

authors： Jacob D,Schumacher G,Bahra M,Davis J,Zhu HB,Zhang LD,Teraishi F,Neuhaus P,Fang BL

更新日期：2005-05-07 00:00:00

abstract：AIM:To develop a novel Helicobacter pylori (H. pylori) CagA antibody enzyme-linked immunosorbent assay (ELISA) suitable for detecting serum anti-CagA antibodies with high sensitivity. METHODS:Recombinant East Asian-type CagA protein was purified and immobilized for ELISA. Serum samples from 217 Vietnamese individuals ...

journal_title：World journal of gastroenterology

authors： Matsuo Y,Kido Y,Akada J,Shiota S,Binh TT,Trang TT,Dung HD,Tung PH,Tri TD,Thuan NP,Tam LQ,Nam BC,Khien VV,Yamaoka Y

更新日期：2017-01-07 00:00:00

abstract：AIM:To evaluate the safety of Curcuma aromatica oil gelatin microspheres (CAO-GMS) infused via hepatic artery against primary liver cancer. METHODS:The safety of CAO-GMS was evaluated in view of its acute toxicity in rats, long-term toxicity in Beagle dogs and general pharmacology in rats and mongrel dogs. RESULTS:Th...

journal_title：World journal of gastroenterology

authors： Deng SG,Wu ZF,Li WY,Yang ZG,Chang G,Meng FZ,Mo LL

更新日期：2004-09-15 00:00:00

abstract：AIM:To develop a novel method for the rapid and efficient extraction of exosomes secreted by tumor cells. METHODS:Unlike the traditional extraction method, the supernatants of cell cultures were concentrated, and the exosomes were isolated promptly and effectively using a novel nanomaterial called ExoQuick. Coomassie ...

journal_title：World journal of gastroenterology

authors： Zhu L,Qu XH,Sun YL,Qian YM,Zhao XH

更新日期：2014-06-07 00:00:00

abstract：:Direct acting antivirals (DAAs) have revolutionized the treatment of hepatitis C virus (HCV) infection, achieving high rates (≥ 95%) of sustained virological response, with a good safety profile and high compliance rates. Consequently, it had been expected that viral clearance will reduce morbidity and mortality rates...

journal_title：World journal of gastroenterology

authors： Muzica CM,Stanciu C,Huiban L,Singeap AM,Sfarti C,Zenovia S,Cojocariu C,Trifan A

更新日期：2020-11-21 00:00:00

abstract：AIM:To assess the incidence of hepatocellular carcinoma (HCC) in chronic liver disease due to hepatitis B virus (HBV) or hepatitis C virus (HCV) coinfected with human immunodeficiency virus (HIV). METHODS:A retrospective cohort study was performed, including patients with chronic liver disease due to HBV or HCV, with ...

journal_title：World journal of gastroenterology

authors： Marcon PDS,Tovo CV,Kliemann DA,Fisch P,de Mattos AA

更新日期：2018-02-07 00:00:00

abstract：AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

journal_title：World journal of gastroenterology

authors： Ding LA,Li JS

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Unconjugated bilirubin (UCB) is generally considered toxic but has gained recent prominence for its anti-inflammatory properties. However, the effects of it on the interaction between intestinal flora and organisms and how it influences immune responses remain unresolved. AIM:To investigate the role of UCB ...

journal_title：World journal of gastroenterology

authors： Zheng JD,He Y,Yu HY,Liu YL,Ge YX,Li XT,Li X,Wang Y,Guo MR,Qu YL,Qin XF,Jiang MS,Wang XH

更新日期：2019-04-21 00:00:00

abstract：AIM:To elucidate the underlying mechanisms of metastasis and to identify the metabolomic markers of gastric cancer metastasis. METHODS:Gastric tumors from metastatic and non-metastatic groups were used in this study. Metabolites and different metabolic patterns were analyzed by gas chromatography, mass spectrometry an...

journal_title：World journal of gastroenterology

authors： Chen JL,Tang HQ,Hu JD,Fan J,Hong J,Gu JZ

更新日期：2010-12-14 00:00:00

abstract：:Gallstone ileus is a rare disease and accounts for 1%-4% of all cases of mechanical intestinal obstruction. It usually occurs in the elderly with a female predominance and may result in a high mortality rate. Its diagnosis is difficult and early diagnosis could reduce the mortality. Surgery remains the mainstay of tre...

journal_title：World journal of gastroenterology

authors： Chou JW,Hsu CH,Liao KF,Lai HC,Cheng KS,Peng CY,Yang MD,Chen YF

更新日期：2007-02-28 00:00:00

abstract：AIM:To determine the evolution of transient elastography (TE) in patients with alcoholic liver disease according to alcohol cessation or continuation. METHODS:We retrospectively selected in our local database all patients who had two TE between June 2005 and November 2010 with chronic alcohol excessive consumption and...

journal_title：World journal of gastroenterology

authors： Bardou-Jacquet E,Legros L,Soro D,Latournerie M,Guillygomarc'h A,Le Lan C,Brissot P,Guyader D,Moirand R

更新日期：2013-01-28 00:00:00

abstract：AIM:To investigate the association of nuclear morphometry and DNA content with resectability of pancreatic cancer. METHODS:A total of 36 patients with pancreatic adenocarcinoma were divided into resectable group and unresectable group. The nuclear morphometry and DNA contents of tumor cells were analyzed by IBAS autoi...

journal_title：World journal of gastroenterology

authors： He YC,Peng W,Qiao JG,Cao J,Chen JW

更新日期：2003-08-01 00:00:00

abstract：AIM:To study the efficacy and factors associated with a sustained virological response (SVR) in chronic hepatitis C (CHC) relapsing patients. METHODS:Out of 1228 CHC patients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV), 165 (13%) had a relapse. Among these, 62 patients were retreated with PEG-IFN-α...

journal_title：World journal of gastroenterology

authors： Stern C,Martinot-Peignoux M,Ripault MP,Boyer N,Castelnau C,Valla D,Marcellin P

更新日期：2012-06-21 00:00:00

abstract：:Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the pathogenesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present sys...

journal_title：World journal of gastroenterology

authors： Salari P,Abdollahi M

更新日期：2011-10-14 00:00:00

abstract：:Colorectal cancer is a major cause of cancer-related death in many countries. Colorectal carcinogenesis is a stepwise process which, from normal mucosa leads to malignancy. Many factors have been shown to influence this process, however, at present, several points remain obscure. In recent years some hypotheses have b...

journal_title：World journal of gastroenterology

authors： Mariani F,Sena P,Roncucci L

更新日期：2014-08-07 00:00:00

abstract：AIM:To investigate the ability of histamine to modulate tryptase release from human colon mast cells and the potential mechanisms. METHODS:Enzymatically dispersed cells from human colons were challenged with histamine, anti-IgE or calcium ionophore A23187 (CI), and the cell supernatants after challenge were collected....

journal_title：World journal of gastroenterology

authors： He SH,Xie H

更新日期：2004-02-01 00:00:00

abstract：:In recent years, a number of studies detected a significantly higher prevalence of Campylobacter species such as Campylobacter concisus (C. concisus) in intestinal biopsies and fecal samples collected from patients with inflammatory bowel disease (IBD) compared to controls. Most of these Campylobacter species are not ...

journal_title：World journal of gastroenterology

authors： Zhang L

更新日期：2015-08-21 00:00:00

abstract：AIM:To explore the cooperative effects of antisense oligonucleotide (ASON) of cell adhesion molecules and cimetidine on the expression of E-selectin and ICAM-1 in endothelial cells and their adhesion to tumor cells. METHODS:After treatment of endothelial cells with ASON and/or cimetidine and induction with TNF-alpha, ...

journal_title：World journal of gastroenterology

authors： Tang NH,Chen YL,Wang XQ,Li XJ,Yin FZ,Wang XZ

更新日期：2004-01-01 00:00:00

abstract：AIM:To investigate the effect and mechanism of action of the nitric oxide synthase (NOS) inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on invasion and metastasis of human colorectal cancer cell line SL-174T. METHODS:Human colorectal cancer cell line SL-174T was cultured and treated separately with four different...

journal_title：World journal of gastroenterology

authors： Yu LB,Dong XS,Sun WZ,Zhao DL,Yang Y

更新日期：2005-10-28 00:00:00

abstract：AIM:To study the clinical outcome of antiviral therapy in hepatitis B-related decompensated cirrhotic patients. METHODS:Three hundred and twelve patients with decompensated hepatitis B cirrhosis were evaluated in a prospective cohort. With two years of follow-up, 198 patients in the group receiving antiviral therapy w...

journal_title：World journal of gastroenterology

authors： Li L,Liu W,Chen YH,Fan CL,Dong PL,Wei FL,Li B,Chen DX,Ding HG

更新日期：2013-12-07 00:00:00

abstract：:AIM:To observe the tumor inhibitory effects by transfecting IL-6 cDNA into colon cancer cell line HT-29 with retroviral vector pZIP cDNA.METHODS:Human IL-6 gene was reconstructed in retrovirus vector and transfected into incasing cells PA317 by lipofectamine mediated method, the clones of the cells transferred with hI...

journal_title：World journal of gastroenterology

authors： Xiao B,Jing B,Zhang YL,Zhou DY,Zhang WD

更新日期：2000-02-01 00:00:00

abstract：AIM:To study the practical use of the model for end-stage liver disease (MELD) on clinic and assess its validity by the concordance (C)-statistic in predicting the prognosis of the patient with severe viral hepatitis. METHODS:One hundred and twenty-one patients were divided into plasma exchange group and non-plasma ex...

journal_title：World journal of gastroenterology

authors： Weng ZH,Cai SQ

更新日期：2005-02-14 00:00:00

abstract：:Multiple pathogenic mechanisms have been implicated in autoimmune hepatitis, but they have not fully explained susceptibility, triggering events, and maintenance or escalation of the disease. Furthermore, they have not identified a critical defect that can be targeted. The goals of this review are to examine the diver...

journal_title：World journal of gastroenterology

authors： Czaja AJ

更新日期：2019-12-07 00:00:00

abstract：:Recently, there have been reports from liver biopsies that showed the progression of liver fibrosis in liver transplant patients after the cessation of immunosuppression. Herein, we focused on activated hepatic stellate cells expressing alpha smooth muscle actin (α-SMA) to understand the correlation between immunosupp...

journal_title：World journal of gastroenterology

authors： Hirabaru M,Mochizuki K,Takatsuki M,Soyama A,Kosaka T,Kuroki T,Shimokawa I,Eguchi S

更新日期：2014-06-14 00:00:00