Antiviral drug resistance increases hepatocellular carcinoma: a prospective decompensated cirrhosis cohort study.

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis and advanced hepatic fibrosis. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked w...

journal_title：World journal of gastroenterology

authors： Fotbolcu H,Zorlu E

更新日期：2016-04-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) is the most common infection in humans, with a marked disparity between developed and developing countries. Although H. pylori infections are asymptomatic in most infected individuals, they are intimately related to malignant gastric conditions such as gastric cancer and gastric mucosa-...

journal_title：World journal of gastroenterology

authors： Campuzano-Maya G

更新日期：2014-09-28 00:00:00

abstract：:In recent years, a number of studies detected a significantly higher prevalence of Campylobacter species such as Campylobacter concisus (C. concisus) in intestinal biopsies and fecal samples collected from patients with inflammatory bowel disease (IBD) compared to controls. Most of these Campylobacter species are not ...

journal_title：World journal of gastroenterology

authors： Zhang L

更新日期：2015-08-21 00:00:00

abstract：:Benign multicystic peritoneal mesothelioma (BMPM) is a rare cystic mesothelial lesion that occurs predominantly in reproductive aged women. A 56-year-old Caucasian male was admitted to our surgical department with a chief complaint of a painful mass in his right lower abdomen for almost 2 years. The physical examinati...

journal_title：World journal of gastroenterology

authors： Wang TB,Dai WG,Liu DW,Shi HP,Dong WG

更新日期：2013-10-21 00:00:00

abstract：:The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

journal_title：World journal of gastroenterology

authors： Goh BK

更新日期：2015-09-14 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography (ERCP) is a state of the art diagnostic and therapeutic procedure for various pancreatic and biliary problems. In spite of the well-established safety of the procedure, there is still a risk of complications such as pancreatitis, cholangitis, bleeding and perforation. Air...

journal_title：World journal of gastroenterology

authors： Yilmaz B,Roach EC,Koklu S,Aydin O,Unlu O,Kilic YA

更新日期：2015-04-21 00:00:00

abstract：:Hepatitis B virus (HBV) infection is still the most common cause of hepatocellular carcinoma and liver cirrhosis world wide. Recently, however, there has been quite dramatic improvement in the understanding of HBV associated liver disease and its treatment. It has become clear that high viral replication is a major ri...

journal_title：World journal of gastroenterology

authors： Tillmann HL

更新日期：2007-01-07 00:00:00

abstract：AIM:To study the inhibitory effects of a Shuangling Fuzheng anticancer preparation (SFAP) on the human gastric cancer cell line SGC-7901 in vitro as well as its immune-modulated effects in a cyclophosphamide-treated murine model. METHODS:MTT experiments and immunocytochemistry ABC experiments were performed for detect...

journal_title：World journal of gastroenterology

authors： Chen HS,Chen J,Cui DL,Zheng YY,Xu AH,Chen G,Jia LC

更新日期：2007-12-28 00:00:00

abstract：AIM:To evaluate whether contrast enhanced ultrasound (CEUS) might also be used for response prediction and early response evaluation in patients receiving bevacizumab based chemotherapy for metastasized colorectal cancer. METHODS:Thirty consecutive patients with non primary resectable liver metastases from colorectal ...

journal_title：World journal of gastroenterology

authors： Schirin-Sokhan R,Winograd R,Roderburg C,Bubenzer J,do Ó NC,Guggenberger D,Hecker H,Trautwein C,Tischendorf JJ

更新日期：2012-02-14 00:00:00

abstract：:Most pancreatic cancer patients present with advanced metastatic disease, resulting in extremely poor 5-year survival, mainly because of the lack of a reliable modality for early detection and limited therapeutic options for advanced disease. Therefore, there is a need for minimally-invasive diagnostic tools for detec...

journal_title：World journal of gastroenterology

authors： Takai E,Yachida S

更新日期：2016-10-14 00:00:00

abstract：AIM:To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels. METHODS:Ten male patients with HCV-related chronic hepatitis and 16 healthy male volunteers were studied. In all subjects seminal parameters (nemaspermic concentration...

journal_title：World journal of gastroenterology

authors： Durazzo M,Premoli A,Di Bisceglie C,Bertagna A,Faga E,Biroli G,Manieri C,Bo S,Pagano G

更新日期：2006-05-21 00:00:00

abstract：AIM:To investigate the risk association and compare the onset age of hepatocellular carcinoma (HCC) patients in Taiwan with different genotypes of MDM2-SNP309. METHODS:We analyzed MDM2-SNP309 genotypes from 58 patients with HCC and 138 cancer-free healthy controls consecutively. Genotyping of MDM2-SNP309 was conducted...

journal_title：World journal of gastroenterology

authors： Leu JD,Lin IF,Sun YF,Chen SM,Liu CC,Lee YJ

更新日期：2009-11-28 00:00:00

abstract：:Acute liver failure is a rare and devastating clinical condition. At present, emergency liver transplantation is the only life-saving therapy in advanced cases, yet the feasibility of transplantation is affected by the presence of systemic inflammation, infection and resultant multi-organ failure. The importance of im...

journal_title：World journal of gastroenterology

authors： Donnelly MC,Hayes PC,Simpson KJ

更新日期：2016-07-14 00:00:00

abstract：AIM:To compare gene expression profiles of pancreatic adenocarcinoma tissue specimens, human pancreatic and colon adenocarcinoma and leukemia cell lines and normal pancreas samples in order to distinguish differentially expressed genes and to validate the differential expression of a subset of genes by quantitative rea...

journal_title：World journal of gastroenterology

authors： Laurell H,Bouisson M,Berthelemy P,Rochaix P,Dejean S,Besse P,Susini C,Pradayrol L,Vaysse N,Buscail L

更新日期：2006-06-07 00:00:00

abstract：:Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of virally infected cells in the liver is related to the HCV-induced inability of the immune system to reco...

journal_title：World journal of gastroenterology

authors： Osna NA

更新日期：2009-03-14 00:00:00

abstract：:The impact of a chronic disease such as inflammatory bowel disease (IBD) on sexual functioning and body image can significantly impair the quality of life of patients. This review considers the sexual and fertility aspects of IBD patients and their daily management. Modern IBD healthcare management should include appr...

journal_title：World journal of gastroenterology

authors： Leenhardt R,Rivière P,Papazian P,Nion-Larmurier I,Girard G,Laharie D,Marteau P

更新日期：2019-09-28 00:00:00

abstract：AIM:To evaluate the efficacy and safety of capsule oxymatrine in the treatment of chronic hepatitis B. METHODS:A randomised double-blind and placebo-controlled multicenter trial was conducted. Injection of oxymatrine was used as positive-control drug. A total of 216 patients with chronic hepatitis B entered the study ...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Mao YM,Li JQ,Wan MB,Li CZ,Chen CW,Fu QC,Wang JY,She WM,Cai X,Ye J,Zhou XQ,Wang H,Wu SM,Tang MF,Zhu JS,Chen WX,Zhang HQ

更新日期：2003-11-01 00:00:00

abstract：:AIM:To investigate the expression of somatostatin mRNA in various differentiated types of gastric carcinoma.METHODS: By using in situ hybridization and immunohistochemical techniques, the expression of somatostatin mRNA and somatostatin immunoreactivity in the normal gastric mucosa, the poorly, moderately and well-dif...

journal_title：World journal of gastroenterology

authors： Zhang QX,Dou YL,Shi XY,Ding Y

更新日期：1998-02-01 00:00:00

abstract：:Biodegradable stents (BDSs) are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines. The experience with the currently the only BDS for endoscopic placement, made of Poly-dioxanone, have shown promising results. However some aspects should be imp...

journal_title：World journal of gastroenterology

authors： Lorenzo-Zúñiga V,Moreno-de-Vega V,Marín I,Boix J

更新日期：2014-03-07 00:00:00

abstract：:AIM:To evaluate a culture system for bile acid formation in primary human hepatocytes in comparison with HepG2 cells.METHODS:Hepatocytes were isolated from normal human liver tissue and we re cultured in serum-free William's E medium.The medium was collected and re newed every 24 h. Bile acids and their precursors in ...

journal_title：World journal of gastroenterology

authors： Einarsson C,Ellis E,Abrahamsson A,Ericzon BG,Bjorkhem I,Axelson M

更新日期：2000-08-01 00:00:00

abstract：AIM:To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS:Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean ...

journal_title：World journal of gastroenterology

authors： Hwang J,Kim JS,Kim AY,Lim JS,Kim SH,Kim MJ,Kim MS,Song KD,Woo JY

更新日期：2017-07-07 00:00:00

abstract：AIM:To explore the expression of macrophage inflammatory protein-1alpha (MIP-1alpha) in Kupffer cells (KCs) following liver ischemia/reperfusion injury IRI in rats. METHODS:Forty male SD rats were divided randomly into five groups. A model of partial warm ischemia/reperfusion injury in the rat liver was established. K...

journal_title：World journal of gastroenterology

authors： Ma W,Wang ZR,Shi L,Yuan Y

更新日期：2006-06-28 00:00:00

abstract：AIM:To investigate the effect of Danzhijiangtang capsule (DJC) on monocyte chemoattractant protein-1 (MCP-1) mRNA expression in newly diagnosed type 2 diabetes mellitus (T2DM) subclinical vascular lesions. METHODS:Sixty-two patients with newly diagnosed T2DM subclinical vascular lesions were randomly divided into a co...

journal_title：World journal of gastroenterology

authors： Fang ZH,Liu Y,Bao TT,Ni YQ,Liu J,Shi GB,Wu JP,Yang JP,Zhang H

更新日期：2013-05-21 00:00:00

abstract：:It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesio...

journal_title：World journal of gastroenterology

authors： Lee H,Son HJ,Rhee PL,Kim JJ,Rhee JC

更新日期：2007-07-28 00:00:00

abstract：:Acute pancreatitis constitutes 3% of all admissions with abdominal pain. There are reports of osteal fat necrosis leading to periosteal reactions and osteolytic lesions following severe pancreatitis, particularly in long bones. A 54-year-old man was admitted to our hospital with acute pancreatitis, who later developed...

journal_title：World journal of gastroenterology

authors： Muthukumarasamy G,Shanmugam V,Yule SR,Ravindran R

更新日期：2007-07-21 00:00:00

abstract：:While therapeutic strategies able to change the natural history of the disease are developing, it is of major importance to have available predictive factors for aggressive disease to try and target these therapeutic strategies. Clinical predictors have probably been the most broadly studied. In both Crohn's disease (...

journal_title：World journal of gastroenterology

authors： Louis E,Belaiche J,Reenaers C

更新日期：2010-06-07 00:00:00

abstract：AIM:To assess the diagnostic value of a laparoscopic finding of a hepatic subcapsular spider-like telangiectasis (HSST) sign in biliary atresia. METHODS:A retrospective study was conducted first and then a validation set was used to investigate the value of an HSST sign in predicting biliary atresia (BA). In the retro...

journal_title：World journal of gastroenterology

authors： Zhou Y,Jiang M,Tang ST,Yang L,Zhang X,Yang DH,Xiong M,Li S,Cao GQ,Wang Y

更新日期：2017-10-21 00:00:00

abstract：AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

journal_title：World journal of gastroenterology

authors： Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

更新日期：2002-02-01 00:00:00

abstract：:The discovery of induced pluripotent stem cells (iPSCs) unraveled a mystery in stem cell research, after identification of four re-programming factors for generating pluripotent stem cells without the need of embryos. This breakthrough in generating iPSCs from somatic cells has overcome the ethical issues and immune r...

journal_title：World journal of gastroenterology

authors： Subba Rao M,Sasikala M,Nageshwar Reddy D

更新日期：2013-06-14 00:00:00

abstract：AIM:To investigate the predictive clinical value of in vitro 3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide (MTT) assay for directing chemosensitivity in patients with gastric cancer. METHODS:Results of a total of 353 consecutive patients with gastric cancer treated with MTT-directed chemotherapy or phys...

journal_title：World journal of gastroenterology

authors： Wu B,Zhu JS,Zhang Y,Shen WM,Zhang Q

更新日期：2008-05-21 00:00:00