Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound.

abstract：:Gastrointestinal cancers represent a major cause of morbidity and mortality, with incomplete response to chemotherapy in the advanced stages and poor prognosis. Angiogenesis plays a crucial part in tumor growth and metastasis, with most gastrointestinal cancers depending strictly on the development of a new and devote...

journal_title：World journal of gastroenterology

authors： Gheonea DI,Cârţână T,Ciurea T,Popescu C,Bădărău A,Săftoiu A

更新日期：2011-01-07 00:00:00

abstract：AIM:To investigate whether regional geography influences ethnic and gender trends for the development of gastric cancer (GC). METHODS:This retrospective analysis of the INVISION patient database at Louisiana State University Health Sciences Center-Shreveport (LSUHSC-S), a southern United States regional hospital, was ...

journal_title：World journal of gastroenterology

authors： Suryawala K,Soliman D,Mutyala M,Nageeb S,Boktor M,Seth A,Aravantagi A,Sheth A,Morris J,Jordan P,Manas K,Cvek U,Trutschl M,Becker F,Alexander J

更新日期：2015-07-07 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is a critical risk factor for the carcinogenesis and progression of hepatocellular carcinoma (HCC). It promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Effective antiviral treatments...

journal_title：World journal of gastroenterology

authors： Zhang YQ,Guo JS

更新日期：2015-04-07 00:00:00

abstract：:Ghrelin, as a kind of multifunctional protein polypeptide, is mainly produced in the fundus of the stomach and can promote occurrence and development of many tumors, including gastrointestinal tumors, which has been proved by the relevant researches. Most gastrointestinal stromal tumors (GISTs, about 80%), as the most...

journal_title：World journal of gastroenterology

authors： Zhu CZ,Liu D,Kang WM,Yu JC,Ma ZQ,Ye X,Li K

更新日期：2017-03-14 00:00:00

abstract：AIM:To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice. METHODS:Balb/c mice were fed with the fermented milk for 7 d after inducing gastritis with acetyl-salicylic acid (ASA, 400 m...

journal_title：World journal of gastroenterology

authors： Rodríguez C,Medici M,Mozzi F,Font de Valdez G

更新日期：2010-04-07 00:00:00

abstract：:RNA sequencing is the use of high throughput next generation sequencing technology to survey, characterize, and quantify the transcriptome of a genome. RNA sequencing has been used to analyze the pathogenesis of several malignancies such melanoma, lung cancer, and colorectal cancer. RNA sequencing can identify differe...

journal_title：World journal of gastroenterology

authors： Gao M,Zhong A,Patel N,Alur C,Vyas D

更新日期：2017-04-28 00:00:00

abstract：:There was remarkable progress in the understanding of the role genetic risk factors in chronic pancreatitis. These factors seem to be much more important than thought in the past. The rare autosomal-dominant mutations N29I and R122H of PRSS1 (cationic trypsinogen) as well as the variant N34S of SPINK1 (pancreatic secr...

journal_title：World journal of gastroenterology

authors： Keim V

更新日期：2008-02-21 00:00:00

abstract：AIM:To investigate the role of insulin-like growth factor binding protein-7 (IGFBP-7) in the activation and transdifferentiation of hepatic stellate cells (HSC) in vitro. METHODS:Rat HSC-T6 cells were cultured in separate dishes and treated with various concentration of transforming growth factor (TGF)-beta(1), IGFBP-...

journal_title：World journal of gastroenterology

authors： Liu LX,Huang S,Zhang QQ,Liu Y,Zhang DM,Guo XH,Han DW

更新日期：2009-07-14 00:00:00

abstract：AIM:To develop a potent and safe gene therapy for esophageal cancer. METHODS:An expression vector carrying fusion suicide gene (yCDglyTK) and shRNA against vascular endothelial growth factor (VEGF) was constructed and delivered into EC9706 esophageal cancer cells by calcium phosphate nanoparticles (CPNP). To achieve t...

journal_title：World journal of gastroenterology

authors： Liu T,Wu HJ,Liang Y,Liang XJ,Huang HC,Zhao YZ,Liao QC,Chen YQ,Leng AM,Yuan WJ,Zhang GY,Peng J,Chen YH

更新日期：2016-06-21 00:00:00

abstract：AIM:To observe the kinetics of D (-)-lactate alteration in both portal and systemic circulation systems, and its relationship with intestinal injury in rats subjected to acute intestinal ischemia-reperfusion. METHODS:Anesthetized rats underwent a 75-min superior mesenteric artery occlusion followed by a 6-h reperfusio...

journal_title：World journal of gastroenterology

authors： Yao YM,Yu Y,Wu Y,Lu LR,Sheng ZY

更新日期：1997-12-15 00:00:00

abstract：AIM:To investigate the hotspots, direction, and the time course of evolution of hepatitis A virus in the process of consecutive cell culture passage in human KMB17 diploid cells. METHODS:Wild type hepatitis A virus H2w was serially propagated in KMB17 cells until passage 30, and the full-length genomes of H2w and its ...

journal_title：World journal of gastroenterology

authors： Tang CH,Mao JS,Chai SA,Chen Y,Zhuang FC

更新日期：2007-09-14 00:00:00

abstract：AIM:To assess the association between smoking and alcohol consumption and extrahepatic cholangiocarcinoma (ECC) through a meta-analysis of clinical observational studies. METHODS:A literature search was conducted using Embase and MEDLINE databases from inception to 31 May 2013 without language limitations, and by manu...

journal_title：World journal of gastroenterology

authors： Ye XH,Huai JP,Ding J,Chen YP,Sun XC

更新日期：2013-12-14 00:00:00

abstract：AIM:To assess the rate of infection, appropriateness of antimicrobial-therapy and mortality on intensive care unit (ICU). Special focus was drawn on patients with liver cirrhosis. METHODS:The study was approved by the local ethical committee. All patients admitted to the Internal Medicine-ICU between April 1, 2007 and...

journal_title：World journal of gastroenterology

authors： Friedrich-Rust M,Wanger B,Heupel F,Filmann N,Brodt R,Kempf VA,Kessel J,Wichelhaus TA,Herrmann E,Zeuzem S,Bojunga J

更新日期：2016-04-28 00:00:00

abstract：AIM:To establish the prognosis and feasibility of en-bloc vascular resection of stage II pancreatic adenocarcinoma of the head and uncinate process. METHODS:We retrospectively analyzed 87 patients with stage II pancreatic adenocarcinoma, who were subjected to pancreaticoduodenectomy (PD) and pylorus-preserving PD (PPP...

journal_title：World journal of gastroenterology

authors： Chakravarty KD,Hsu JT,Liu KH,Yeh CN,Yeh TS,Hwang TL,Jan YY,Chen MF

更新日期：2010-02-28 00:00:00

abstract：:Pernicious anemia (PA) is a macrocytic anemia that is caused by vitamin B(12) deficiency, as a result of intrinsic factor deficiency. PA is associated with atrophic body gastritis (ABG), whose diagnosis is based on histological confirmation of gastric body atrophy. Serological markers that suggest oxyntic mucosa damag...

journal_title：World journal of gastroenterology

authors： Lahner E,Annibale B

更新日期：2009-11-07 00:00:00

abstract：:Biodegradable stents (BDSs) are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines. The experience with the currently the only BDS for endoscopic placement, made of Poly-dioxanone, have shown promising results. However some aspects should be imp...

journal_title：World journal of gastroenterology

authors： Lorenzo-Zúñiga V,Moreno-de-Vega V,Marín I,Boix J

更新日期：2014-03-07 00:00:00

abstract：AIM:To evaluate the effects of ethanol on the insulin-like growth factor-I (IGF-I) system involved in c-Jun N-terminal kinase (JNK1/2) and alcoholdehydrogenase (ADH) activity in primary cultured rat hepatocytes. METHODS:Hepatocytes isolated from male Sprague-Dawley rats were incubated with various concentrations of et...

journal_title：World journal of gastroenterology

authors： Oh YI,Kim JH,Kang CW

更新日期：2008-07-21 00:00:00

abstract：:Synchronous occurrence of epithelial neoplasia and gastrointestinal stromal tumor (GIST) in the stomach is uncommon. Only rare cases have been reported in the literature. We present here a 60-year-old female case of synchronous occurrence of gastric high-level intraepithelial neoplasia and GIST with the features of 22...

journal_title：World journal of gastroenterology

authors： Mou YP,Xu XW,Xie K,Zhou W,Zhou YC,Chen K

更新日期：2010-10-21 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this article, we describe the clinical course of a patient who developed a pancreatic recurrence of RCC and 1 yea...

journal_title：World journal of gastroenterology

authors： Riviello C,Tanini I,Cipriani G,Pantaleo P,Nozzoli C,Poma A,Riccardo V,Valeri A

更新日期：2006-08-28 00:00:00

abstract：AIM:To investigate the frequency and timing of post-partum chronic hepatitis B virus (HBV) reactivation and identify its pre-partum predictors. METHODS:Forty-one hepatitis B e antigen (HBeAg)-negative chronic HBV infected pregnant women were prospectively evaluated between the 28th and the 32nd week of gestation. Subj...

journal_title：World journal of gastroenterology

authors： Elefsiniotis I,Vezali E,Vrachatis D,Hatzianastasiou S,Pappas S,Farmakidis G,Vrioni G,Tsakris A

更新日期：2015-01-28 00:00:00

abstract：:It is common practice to follow patients with colorectal cancer for some years after resection and/or adjuvant treatment. Data are lacking about how often patients should be seen, what tests should be performed, and what surveillance strategy has a significant impact on patient outcome. Seven randomized trials have ad...

journal_title：World journal of gastroenterology

authors： Rosati G

更新日期：2010-03-28 00:00:00

abstract：AIM:To investigate the relationship of serum levels of polyunsaturated fatty acid (PUFA) with kinds of cytokines in colorectal cancer (CRC). METHODS:Serum samples of 100 CRC patients were collected. The concentration of total n-3 PUFA which included C18:3 n-3, C20:5 n-3, C22:5 n-3, C22:6 n-3 and the total n-6 PUFA inc...

journal_title：World journal of gastroenterology

authors： Jia HJ,Zhang PJ,Liu YL,Jiang CG,Zhu X,Tian YP

更新日期：2016-02-28 00:00:00

abstract：AIM:To establish novel intestinal myofibroblast (IMF) cell lines from mouse colonic mucosa and investigate their biological characters. METHODS:Primary IMFs were isolated from mucosal tissues of mouse colon that was denuded of epithelial cells and smooth muscle layer. For immortalization, primary IMFs were transfected...

journal_title：World journal of gastroenterology

authors： Kawasaki H,Ohama T,Hori M,Sato K

更新日期：2013-05-07 00:00:00

abstract：:Anti-tumor necrosis factor alpha (TNF-alpha) inhibitors are effective in the treatment of various inflammatory rheumatic conditions. Increased risks of serious infections are the major issues concerning the long-term safety of these agents. We present a case of a young male Behcet's patient whose disease was complicat...

journal_title：World journal of gastroenterology

authors： Sari I,Birlik M,Gonen C,Akar S,Gurel D,Onen F,Akkoc N

更新日期：2008-05-14 00:00:00

abstract：:Multiple studies have demonstrated alterations in the intestinal microbial community (termed the microbiome) in Crohn's disease (CD) and several lines of evidence suggest these changes may have a significant role in disease pathogenesis. In active and quiescent disease, both the faecal and mucosa-associated microbiome...

journal_title：World journal of gastroenterology

authors： Tawfik A,Flanagan PK,Campbell BJ

更新日期：2014-07-21 00:00:00

abstract：:More than five years ago, the treatment of hepatitis C virus infection was revolutionized with the introduction of all-oral direct-acting antiviral (DAA) drugs. They proved highly efficient in curing patients with chronic hepatitis C (CHC), including patients with cirrhosis. The new DAA treatments were alleged to indu...

journal_title：World journal of gastroenterology

authors： Laursen TL,Sandahl TD,Kazankov K,George J,Grønbæk H

更新日期：2020-06-14 00:00:00

abstract：:Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic miRNAs and downregulated tumour-suppressor miRNAs in this type of cancer. In this review, we provide an overview of the role of mi...

journal_title：World journal of gastroenterology

authors： da Silva Oliveira KC,Thomaz Araújo TM,Albuquerque CI,Barata GA,Gigek CO,Leal MF,Wisnieski F,Rodrigues Mello Junior FA,Khayat AS,de Assumpção PP,Rodriguez Burbano RM,Smith MC,Calcagno DQ

更新日期：2016-09-21 00:00:00

abstract：AIM:To investigate the biological function of complete S protein and to look for proteins interacting with complete S protein in hepatocytes. METHODS:We constructed bait plasmid expressing complete S protein of HBV by cloning the gene of complete S protein into pGBKT7, then the recombinant plasmid DNA was transformed ...

journal_title：World journal of gastroenterology

authors： Bai GQ,Cheng J,Zhang SL,Huang YP,Wang L,Liu Y,Lin SM

更新日期：2005-07-07 00:00:00

abstract：:We report the case of a 21-year-old man who was noted to have pneumomediastinum during an admission for an acute flare of ulcerative colitis. At that time, he was on maintenance treatment with azathioprine at a dose of 1.25 mg/kg per day, and had not received supplementary steroids for 9 mo. He had never received anti...

journal_title：World journal of gastroenterology

authors： Lee JC,Bell DC,Guinness RM,Ahmad T

更新日期：2009-04-21 00:00:00

abstract：AIM:To investigate the anticancer mechanisms of the monoterpenoid alcohol linalool in human colon cancer cells. METHODS:The cytotoxic effect of linalool on the human colon cancer cell lines and a human fibroblast cell line was examined using the WST-8 assay. The apoptosis-inducing effect of linalool was measured using...

journal_title：World journal of gastroenterology

authors： Iwasaki K,Zheng YW,Murata S,Ito H,Nakayama K,Kurokawa T,Sano N,Nowatari T,Villareal MO,Nagano YN,Isoda H,Matsui H,Ohkohchi N

更新日期：2016-11-28 00:00:00