Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer.

abstract：AIM:To identify a small, clinically applicable immunohistochemistry (IHC) panel that could be combined with magnetic resonance imaging (MRI)-detected extramural vascular invasion (EMVI) for assessment of prognosis concerning the non-advanced rectal cancer patients prior to operation. METHODS:About 329 patients with pa...

journal_title：World journal of gastroenterology

authors： Li XF,Jiang Z,Gao Y,Li CX,Shen BZ

更新日期：2016-10-14 00:00:00

abstract：AIM:To compare the antisecretory activity and plasma drug concentrations of a single oral dose of 10 mg lafutidine, a novel H2 receptor antagonist, with those of the proton pump inhibitor lansoprazole (LPZ) 30 mg. METHODS:Ten volunteers without H pylori infection participated in this crossover study comparing lafutidi...

journal_title：World journal of gastroenterology

authors： Yamagishi H,Koike T,Ohara S,Horii T,Kikuchi R,Kobayashi S,Abe Y,Iijima K,Imatani A,Suzuki K,Hishinuma T,Goto J,Shimosegawa T

更新日期：2008-04-21 00:00:00

abstract：AIM:To investigate the influence of experimental obstructive jaundice and exogenous bombesin (BBS) and neurotensin (NT) administration on the expression of the tight junction (TJ)-protein claudin-4 in intestinal epithelium of rats. METHODS:Forty male Wistar rats were randomly divided into five groups: I = controls, II...

journal_title：World journal of gastroenterology

authors： Assimakopoulos SF,Vagianos CE,Charonis AS,Alexandris IH,Spiliopoulou I,Thomopoulos KC,Nikolopoulou VN,Scopa CD

更新日期：2006-06-07 00:00:00

abstract：:Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postopera...

journal_title：World journal of gastroenterology

authors： Zhang GF,Chai Y,Li WS,Huang LS,Shen G

更新日期：2014-09-21 00:00:00

abstract：:This paper pays a tribute to Dr. Frank I Tovey on his 90th birthday which happens on September 1, 2011, and briefly describes the major findings in his research career and contributions as follows. The geographical prevalence of duodenal ulceration is related to staple diets. Unrefined wheat and maize, soya, certain p...

journal_title：World journal of gastroenterology

authors： Ma LS

更新日期：2011-08-21 00:00:00

abstract：AIM:To investigate the role of peritoneal macrophage (PM) polarization in the therapeutic effect of abdominal paracentesis drainage (APD) on severe acute pancreatitis (SAP). METHODS:SAP was induced by 5% Na-taurocholate retrograde injection in Sprague-Dawley rats. APD was performed by inserting a drainage tube with a ...

journal_title：World journal of gastroenterology

authors： Liu RH,Wen Y,Sun HY,Liu CY,Zhang YF,Yang Y,Huang QL,Tang JJ,Huang CC,Tang LJ

更新日期：2018-12-07 00:00:00

abstract：AIM:To examine the epidemiology of hepatitis B virus carrier status (HBVC) and sonographic fatty liver (SFL) in Taiwanese adults, and to evaluate their possible interaction in inducing liver damage (LD). >From an epidemiological viewpoint, we analyzed previous studies which indicated that fatty liver sensitizes host im...

journal_title：World journal of gastroenterology

authors： Lin YC,Hsiao ST,Chen JD

更新日期：2007-03-28 00:00:00

abstract：AIM:To investigate the association of serum gamma-glutamyl transferase (GGT) levels with chronic hepatitis B infection and hepatitis B e antigen (HBeAg) seroconversion. METHODS:A retrospective study was performed on clinical data collected from patients who had been positive for hepatitis B surface antigen for > 6 mo ...

journal_title：World journal of gastroenterology

authors： Huang R,Yang CC,Liu Y,Xia J,Su R,Xiong YL,Wang GY,Sun ZH,Yan XM,Lu S,Wu C

更新日期：2015-09-14 00:00:00

abstract：AIM:To elucidate cell proliferation in erosive reflux disease (ERD) and non-erosive reflux disease (NERD), we evaluated markers in squamous epithelial cells. METHODS:Thirty-four consecutive patients with gastroesophageal-reflux-disease-related symptoms (21 NERD and 13 ERD) were evaluated for the enrolment into the stu...

journal_title：World journal of gastroenterology

authors： Calabrese C,Montanaro L,Liguori G,Brighenti E,Vici M,Gionchetti P,Rizzello F,Campieri M,Derenzini M,Trerè D

更新日期：2011-10-28 00:00:00

abstract：AIM:Quasispecies of hepatitis C virus (HCV) are the foundation for rapid sequence evolution of HCV to evade immune surveillance of hosts. The consensus sequence evolution of a segment of HCV NS3 region, which encompasses putative cytotoxic T cell epitopes, was evaluated. METHODS:Three male patients, infected with HCV ...

journal_title：World journal of gastroenterology

authors： Guo HZ,Yin Y,Wang WL,Zhang CS,Wang T,Wang Z,Zhang J,Cheng H,Wang HT

更新日期：2004-03-15 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis and advanced hepatic fibrosis. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked w...

journal_title：World journal of gastroenterology

authors： Fotbolcu H,Zorlu E

更新日期：2016-04-28 00:00:00

abstract：:To review the implication of CXCR4 for gastrointestinal cancer, a "Pubmed" analysis was performed in order to evaluate the relevance of CXCR4 and its ligands for gastrointestinal cancers. Search terms applied were "cancer, malignoma, esophageal, gastric, colon, colorectal, hepatic, pancreatic, CXCR4, SDF-1alpha, and S...

journal_title：World journal of gastroenterology

authors： Schimanski CC,Galle PR,Moehler M

更新日期：2008-08-14 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosine kinase receptor ...

journal_title：World journal of gastroenterology

authors： Zhao Y,Feng F,Guo QH,Wang YP,Zhao R

更新日期：2020-09-14 00:00:00

abstract：AIM:To explore the quantitative analysis of diffusion-weighted magnetic resonance imaging (DWMRI) in differential diagnosis of focal hepatic lesions. METHODS:DWMRI was performed in 149 hepatic lesions, including hepatocellular carcinoma (34 cases), hepatic metastases (37 cases), cavernous hemangioma (42 cases), hepati...

journal_title：World journal of gastroenterology

authors： Sun XJ,Quan XY,Huang FH,Xu YK

更新日期：2005-11-07 00:00:00

abstract：:Hepatitis C is a major cause of liver-related morbidity and mortality worldwide. In fact, chronic hepatitis C is considered as one of the primary causes of chronic liver disease, cirrhosis and hepatocellular carcinoma, and is the most common reason for liver transplantation. The primary objectives for the treatment of...

journal_title：World journal of gastroenterology

authors： Festi D,Sandri L,Mazzella G,Roda E,Sacco T,Staniscia T,Capodicasa S,Vestito A,Colecchia A

更新日期：2004-01-01 00:00:00

abstract：AIM:To investigate the effect of a single amino acid mutation in human class B scavenger receptor I (SR-BI) on the infectivity of cell culture-derived hepatitis C virus (HCVcc) in SR-BI knock-down Huh7-siSR-BI cells. METHODS:Site-directed mutagenesis was used to construct the SR-BI S112F mutation, and the mutation was...

journal_title：World journal of gastroenterology

authors： Gao R,Gao W,Xu G,Xu J,Ren H

更新日期：2017-07-28 00:00:00

abstract：AIM:To evaluate the effects of betaine on the ethanol-induced secretion of IGF-I and IGFBP-1 using radioimmunoassay and Western blotting, respectively, in primary cultured rat hepatocytes. METHODS:Hepatocytes isolated from male Sprague-Dawley rats were incubated with various concentrations of ethanol and PD98059 proce...

journal_title：World journal of gastroenterology

authors： Lee MS,Kim MS,Park SY,Kang CW

更新日期：2006-03-21 00:00:00

abstract：AIM:To evaluate virological response to adefovir (ADV) monotherapy and emergence of ADV-resistant mutations in lamivudine (LAM)-resistant chronic hepatitis B patients. METHODS:Seventy-seven patients with documented LAM resistance who were treated with 10 mg/d ADV for > 96 wk were analyzed for ADV resistance. RESULTS:...

journal_title：World journal of gastroenterology

authors： Sinn DH,Lee HIe,Gwak GY,Choi MS,Koh KC,Paik SW,Yoo BC,Lee JH

更新日期：2011-08-14 00:00:00

abstract：AIM:To understand CD133 promoter hypermethylation and expression in 32 colorectal cancer cell lines. METHODS:Nucleic acid was isolated from 32 colorectal cancer cell lines and CD133 expression levels were measured by reverse transcription-polymerase chain reaction (RT-PCR) and real-time PCR. Promoter methylation statu...

journal_title：World journal of gastroenterology

authors： Jeon YK,Kim SH,Choi SH,Kim KH,Yoo BC,Ku JL,Park JG

更新日期：2010-07-07 00:00:00

abstract：AIM:To determine the clinical effectiveness of intense psychological support to physical activity (PA) in nonalcoholic fatty liver disease (NAFLD), compared with cognitive-behavioral treatment (CBT). METHODS:Twenty-two NAFLD cases received support to exercise, tailored to their motivational needs (PA group). The effec...

journal_title：World journal of gastroenterology

authors： Montesi L,Caselli C,Centis E,Nuccitelli C,Moscatiello S,Suppini A,Marchesini G

更新日期：2014-08-07 00:00:00

abstract：:Unspecific abdominal complaints including bloating and irregular bowel movements may be caused by carbohydrate malabsorption syndromes, e.g., lactose and fructose malabsorption. These symptoms were investigated with hydrogen (H2) breath tests and correlated to carbohydrate malabsorption. During performing these H2-bre...

journal_title：World journal of gastroenterology

authors： Schnedl WJ,Kalmar P,Mangge H,Krause R,Wallner-Liebmann SJ

更新日期：2015-09-21 00:00:00

abstract：:The advances of laparoscopic surgery since the early 1990s have caused one of the largest technical revolutions in medicine since the detection of antibiotics (1922, Flemming), the discovery of DNA structure (1953, Watson and Crick), and solid organ transplantation (1954, Murray). Perseverance through a rocky start an...

journal_title：World journal of gastroenterology

authors： Kaiser AM

更新日期：2014-11-07 00:00:00

abstract：:Statins are a class of molecules that inhibit HMG CoA reductase. They are usually prescribed as a lipid lowering medication. However, there is accumulating evidence that statins have multiple secondary effects both related and unrelated to their lipid-lowering effect. This narrative review of the literature aims to pr...

journal_title：World journal of gastroenterology

authors： Janicko M,Drazilova S,Pella D,Fedacko J,Jarcuska P

更新日期：2016-07-21 00:00:00

abstract：:An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

journal_title：World journal of gastroenterology

authors： Byrnes V,Chopra S,Koziel MJ

更新日期：2007-08-21 00:00:00

abstract：:Severe acute hepatitis of unknown etiology is difficult to treat and often progresses to subacute fulminant hepatitis or late-onset hepatic failure. A 45-year-old well-nourished, healthy man had progressive fatigue and his liver function tests showed severe liver dysfunction. The etiology of sever acute cholestatic he...

journal_title：World journal of gastroenterology

authors： Ohwada S,Kobayashi I,Harasawa N,Tsuda K,Inui Y

更新日期：2009-06-21 00:00:00

abstract：AIM:To investigate the effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents. METHODS:Fifteen samples of autoantibodies against beta(1)-adrenoceptor positive sera of patients with hepatitis virus myocarditis were obtained and IgGs were puri...

journal_title：World journal of gastroenterology

authors： Liu K,Liao YH,Wang ZH,Li SL,Wang M,Zeng LL,Tang M

更新日期：2004-04-15 00:00:00

abstract：AIM:To assess the clinicopathological and biological significance of cripto in human colorectal cancer. METHODS:Real-time reverse-transcription polymerase chain reaction (PCR) was used to examine cripto mRNA levels in primary colon cancer and normal colon tissues as well as normal and metastatic lymph nodes from colon...

journal_title：World journal of gastroenterology

authors： Jiang PC,Zhu L,Fan Y,Zhao HL

更新日期：2013-12-14 00:00:00

abstract：AIM:To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse. METHODS:Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexi...

journal_title：World journal of gastroenterology

authors： Lipp MJ,Pagovich OE,Rabin D,Min AD,Bernstein BB

更新日期：2010-01-21 00:00:00

abstract：:Although recent diagnostic and therapeutic advances have substantially improved the survival of patients with gastric cancer (GC), the overall prognosis is still poor. Surgery is the only curative treatment and should be performed in experienced centers. Due to high relapse following surgery, complementary and systemi...

journal_title：World journal of gastroenterology

authors： Cravo M,Fidalgo C,Garrido R,Rodrigues T,Luz G,Palmela C,Santos M,Lopes F,Maio R

更新日期：2015-11-07 00:00:00

abstract：AIM:To investigate the expression of p28/gankyrin gene and its role in the carcinogenetic process of human hepatocellular carcinoma (HCC). METHODS:64 specimens of HCC and para-carcinoma tissues, 22 specimens of non-tumor liver tissues (7 normal, 15 cirrhosis), 10 specimens of normal human tissues and 5 hepatoma cell l...

journal_title：World journal of gastroenterology

authors： Fu XY,Wang HY,Tan L,Liu SQ,Cao HF,Wu MC

更新日期：2002-08-01 00:00:00