Virological response to adefovir monotherapy and the risk of adefovir resistance.

abstract：AIM:Taurine has been shown to be an effective scavenger of hypochlorous acid (HOCl). The role of HOCl is well established in tissue damage associated with inflammation and injury. In the present study, the effect of HOCl on nuclear nucleoside triphosphatase of hepatocytes and the ability of taurine to prevent this effe...

journal_title：World journal of gastroenterology

authors： Li JX,Pang YZ,Tang CS,Li ZQ

更新日期：2004-03-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is a critical risk factor for the carcinogenesis and progression of hepatocellular carcinoma (HCC). It promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Effective antiviral treatments...

journal_title：World journal of gastroenterology

authors： Zhang YQ,Guo JS

更新日期：2015-04-07 00:00:00

abstract：AIM:To investigate the expression of cyclooxygenase-2 (COX-2) in gastric cancer and its relation with the liver metastasis and prognosis. METHODS:Expression of COX-2 mRNA and protein was examined in gastric cancer and its paired substantial normal tissue by semi-quantitative reverse transcription-polymerase chain reac...

journal_title：World journal of gastroenterology

authors： Yu JR,Wu YJ,Qin Q,Lu KZ,Yan S,Liu XS,Zheng SS

更新日期：2005-08-21 00:00:00

abstract：AIM:To study the characteristics of upper digestive tract diseases (UDTDs) in fishermen who live in Bohai Bay. METHODS:An investigation was carried out in 1488 fishermen with symptoms of UDTDs (aside from liver, biliary and pancreatic diseases) during the time period between December 1991 and February 1995. This inves...

journal_title：World journal of gastroenterology

authors： Wang YB,Wang YP,Zou J,Bai BJ,Ren GC,Cai BQ

更新日期：1997-09-15 00:00:00

abstract：:Mesenchymal stem cells (MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro. It has recently been observed that MSC may also exert a profound immunosuppressive and anti-inflammatory effect both in vitro and in vivo with consequent potential use in autoimmune disorde...

journal_title：World journal of gastroenterology

authors： Taddio A,Tommasini A,Valencic E,Biagi E,Decorti G,De Iudicibus S,Cuzzoni E,Gaipa G,Badolato R,Prandini A,Biondi A,Ventura A

更新日期：2015-04-14 00:00:00

abstract：AIM:To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS:Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function par...

journal_title：World journal of gastroenterology

authors： Pereira RM,dos Santos RA,Oliveira EA,Leite VH,Dias FL,Rezende AS,Costa LP,Barcelos LS,Teixeira MM,Simoes e Silva AC

更新日期：2008-07-28 00:00:00

abstract：AIM:To determine risk factors associated with hepatitis C virus (HCV) treatment failure after direct acting antivirals in patients with complex treatment histories. METHODS:All HCV mono-infected patients who received treatment at our institution were queried. Analysis was restricted to patients who previously failed t...

journal_title：World journal of gastroenterology

authors： Hartman J,Bichoupan K,Patel N,Chekuri S,Harty A,Dieterich D,Perumalswami P,Branch AD

更新日期：2015-11-21 00:00:00

abstract：:In 2018, the pan-Janus kinase (JAK) inhibitor tofacitinib was launched for the treatment of ulcerative colitis (UC). Although tofacitinib has proven efficacious in patients with active UC, it failed in patients with Crohn's disease (CD). This finding strongly hints at a different contribution of JAK signaling in both ...

journal_title：World journal of gastroenterology

authors： Cordes F,Foell D,Ding JN,Varga G,Bettenworth D

更新日期：2020-07-28 00:00:00

abstract：AIM:To develop a conditionally replicative gene-viral vector system called CNHK500-p53, which contains dual promoters within the E1 region, and combines the advantages of oncolytic virus and gene therapies for hepatocellular carcinoma (HCC). METHODS:CNHK500-p53 was constructed by using human telomerase reverse transcr...

journal_title：World journal of gastroenterology

authors： Zhao HC,Zhang Q,Yang Y,Lu MQ,Li H,Xu C,Chen GH

更新日期：2007-02-07 00:00:00

abstract：AIM:To investigate the incidence, characteristics, and risk factors for hepatocellular carcinoma (HCC) in Chinese patients with primary biliary cirrhosis (PBC). METHODS:We reviewed the data of 52 PBC-associated HCC patients treated at Beijing 302 Hospital from January 2002 to December 2013 and analyzed its incidence a...

journal_title：World journal of gastroenterology

authors： Zhang XX,Wang LF,Jin L,Li YY,Hao SL,Shi YC,Zeng QL,Li ZW,Zhang Z,Lau GK,Wang FS

更新日期：2015-03-28 00:00:00

abstract：:The use of non-steroidal anti-inflammatory drugs (NSAIDs) is widespread worldwide thanks to their analgesic, anti-inflammatory and antipyretic effects. However, even more attention is placed upon the recurrence of digestive system complications in the course of their use. Recent data suggests that the complications of...

journal_title：World journal of gastroenterology

authors： Utzeri E,Usai P

更新日期：2017-06-14 00:00:00

abstract：:AIM:To assess the diagnostic values of tumor markers for pancreatic cancer.METHODS:Pancreatic cancer-associated antigen from colonic mucosa (PCAAc), pancreas-specific antigen (PaA), pancreatic oncofetal antigen (POA) and minimolecular pancreatic antigen (mPOA) were detected by double antibodies Sandwich ELISA; CA19-9,...

journal_title：World journal of gastroenterology

authors： Zhao XY,Yu SY,Da SP,Bai L,Guo XZ,Dai XJ,Wang YM

更新日期：1998-04-01 00:00:00

abstract：AIM:Previous reports have shown that decrease in plasma glutamine (Gln) level following major surgery may contribute to the state of immunosuppression. Gln supplementation improves the depletion of body Gln pool, and may have indirect effect on reducing proinflammatory mediator release. This study evaluated whether the...

journal_title：World journal of gastroenterology

authors： Lin MT,Kung SP,Yeh SL,Liaw KY,Wang MY,Kuo ML,Lee PH,Chen WJ

更新日期：2005-10-21 00:00:00

abstract：AIM:To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma and therapeutic outcome. METHODS:Purified anti-CEA monoclonal antibody (McAb) was biotinylated with NHS-biotin, and then radiolabeled with 188Re by the direct method. 188Re-labeled b...

journal_title：World journal of gastroenterology

authors： Li GP,Wang YX,Huang K,Zhang H,Zhang CF

更新日期：2005-04-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most frequent tumors worldwide. The majority of HCC cases occur in patients with chronic liver disease. Despite regular surveillance to detect small HCC in these patients, HCC is often diagnosed at an advanced stage. Because HCC is highly resistant to conventional systemic ...

journal_title：World journal of gastroenterology

authors： Shin JW,Chung YH

更新日期：2013-10-07 00:00:00

abstract：:Inflammatory bowel disease is an important cause of gastrointestinal pathology in children and adolescents. The incidence of pediatric inflammatory bowel disease is increasing; therefore, it is important for the clinician to be aware of the presentation of this disease in the pediatric population. Laboratory tests, ra...

journal_title：World journal of gastroenterology

authors： Diefenbach KA,Breuer CK

更新日期：2006-05-28 00:00:00

abstract：BACKGROUND:B-mode-ultrasound-guided percutaneous cholecystostomy (PC) may be performed by a transhepatic or transperitoneal approach, called percutaneous transhepatic gallbladder drainage (PHGD) and percutaneous transperitoneal gallbladder drainage (PPGD), respectively. We compared the impact of PC related to the route...

journal_title：World journal of gastroenterology

authors： Liu P,Liu C,Wu YT,Zhu JY,Zhao WC,Li JB,Zhang H,Yang YX

更新日期：2020-09-28 00:00:00

abstract：AIM:To evaluate the diagnostic accuracy, sensitivity, specificity of contrast-enhanced computed tomographic colonography in detecting local recurrence of colorectal cancer. METHODS:From January 2000 to December 2004, 434 patients after potentially curative resection for invasive colorectal cancer were followed up for ...

journal_title：World journal of gastroenterology

authors： You YT,Chang Chien CR,Wang JY,Ng KK,Chen JS,Tang R,Chiang JM,Yeh CY,Hsieh PS

更新日期：2006-01-07 00:00:00

abstract：:Inflammatory bowel disease (IBD) results from a complex series of interactions between susceptibility genes, the environment, and the immune system. Recently, some studies provided strong evidence that the process of autophagy affects several aspects of mucosal immune responses. Autophagy is a cellular stress response...

journal_title：World journal of gastroenterology

authors： Iida T,Onodera K,Nakase H

更新日期：2017-03-21 00:00:00

abstract：AIM:To study the value of colonoscopy and selective angiography in diagnosing ischemic enterocolitis. METHODS:Among the 16 cases under study, 10 cases had hypertension and a history of coronary artery disease (one was hospitalized for sub-ventricular-wall infarction). The blood pressure of 10 of the 16 cases ranged fr...

journal_title：World journal of gastroenterology

authors： He L,Luo HS

更新日期：2005-06-28 00:00:00

abstract：AIM:To evaluate the rate of adverse events (AEs) during consecutive gastric and duodenal polypectomies in several Spanish centers. METHODS:Polypectomies of protruded gastric or duodenal polyps ≥ 5 mm using hot snare were prospectively included. Prophylactic measures of hemorrhage were allowed in predefined cases. AEs ...

journal_title：World journal of gastroenterology

authors： Córdova H,Argüello L,Loras C,Naranjo Rodríguez A,Riu Pons F,Gornals JB,Nicolás-Pérez D,Andújar Murcia X,Hernández L,Santolaria S,Leal C,Pons C,Pérez-Cuadrado-Robles E,García-Bosch O,Papo Berger M,Ulla Rocha JL,Sánchez-Mon

更新日期：2017-12-21 00:00:00

abstract：AIM:To detect high risk patients with a progressive disease course of ulcerative colitis (UC) requiring immunosuppressive therapy (IT). METHODS:A retrospective, multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed. Patients were divided into two groups dep...

journal_title：World journal of gastroenterology

authors： Stallmach A,Nickel L,Lehmann T,Bokemeyer B,Bürger M,Hüppe D,Kruis W,Nikolaus S,Preiss JC,Sturm A,Teich N,Schmidt C

更新日期：2014-09-21 00:00:00

abstract：AIM:To explore the cooperative effects of antisense oligonucleotide (ASON) of cell adhesion molecules and cimetidine on the expression of E-selectin and ICAM-1 in endothelial cells and their adhesion to tumor cells. METHODS:After treatment of endothelial cells with ASON and/or cimetidine and induction with TNF-alpha, ...

journal_title：World journal of gastroenterology

authors： Tang NH,Chen YL,Wang XQ,Li XJ,Yin FZ,Wang XZ

更新日期：2004-01-01 00:00:00

abstract：AIM:To examine the extent of use of specific therapies in clinical practice, and their relationship to therapies validated in clinical trials. METHODS:The US National Cancer Institutes' Patterns of Care study was used to examine therapies and survival of patients diagnosed in 2001 with histologically-confirmed gastroe...

journal_title：World journal of gastroenterology

authors： Cronin-Fenton DP,Mooney MM,Clegg LX,Harlan LC

更新日期：2008-05-28 00:00:00

abstract：:Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an...

journal_title：World journal of gastroenterology

authors： Haramura T,Haraguchi M,Irie J,Ito S,Tokai H,Noda K,Kitajima M,Minami S,Inoue K,Sasaki Y,Oshima K,Eguchi S

更新日期：2015-06-28 00:00:00

abstract：:Gastroparesis has traditionally been a largely medically managed disease with refractory symptoms typically falling under the umbrella of the surgical domain. Surgical options include, but are not limited to, gastrostomy, jejunostomy, pyloromyotomy, or pyloroplasty, and the Food and Drug Administration approved gastri...

journal_title：World journal of gastroenterology

authors： McCarty TR,Rustagi T

更新日期：2015-06-14 00:00:00

abstract：AIM:To evaluate the role of endoscopic retrograde cholangiopancreatography (ERCP) in patients with sickle cell disease (SCD). METHODS:Two hundred and twenty four SCD patients with cholestatic jaundice (CJ) had ERCP. The indications for ERCP were based on clinical and biochemical evidence of CJ and ultrasound findings....

journal_title：World journal of gastroenterology

authors： Issa H,Al-Haddad A,Al-Salem A

更新日期：2009-11-14 00:00:00

abstract：:Several studies have demonstrated that the outcome of chronic hepatitis C (CHC) infection is profoundly influenced by a variety of comorbidities. Many of these comorbidities have a significant influence on the response to antiviral therapy. These comorbidities negatively affect the course and outcome of liver disease,...

journal_title：World journal of gastroenterology

authors： El-Zayadi AR

更新日期：2009-10-28 00:00:00

abstract：AIM:To investigate the association of tumor necrosis factor alpha (TNFα) -G308A polymorphism with different liver pathological changes in treatment-naïve Egyptian patients infected with hepatitis C virus (HCV) genotype 4. METHODS:This study included 180 subjects, composed of 120 treatment-naïve chronic HCV patients wi...

journal_title：World journal of gastroenterology

authors： Bader El Din NG,Farouk S,El-Shenawy R,Ibrahim MK,Dawood RM,Elhady MM,Salem AM,Zayed N,Khairy A,El Awady MK

更新日期：2016-09-14 00:00:00

abstract：AIM:To evaluate the efficacy and safety of HL tablet extracted from magnolia officinalis for treating patients with nonalcoholic fatty liver disease (NAFLD). METHODS:Seventy-four patients with NAFLD diagnosed by ultrasonography were randomly assigned to 3 groups given high dose (400 mg) HL tablet, low dose (133.4 mg) ...

journal_title：World journal of gastroenterology

authors： Jeong JY,Sohn JH,Baek YH,Cho YK,Kim Y,Kim H

更新日期：2017-08-28 00:00:00