A tribute to Dr. Frank I Tovey on his 90th birthday.

abstract：AIM:To analyze, retrospectively in a population-based study, the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS:All rectal carcinomas diagnosed during 1998 to 2000 and initially treated w...

journal_title：World journal of gastroenterology

authors： Bakx R,Visser O,Josso J,Meijer S,Slors JF,van Lanschot JJ

更新日期：2008-10-21 00:00:00

abstract：:AIM:To investigate the incidence and management of nutritional deficiencies following a gastrectomy.METHODS:A gastrectomy population of 227 patients in London was followed up for 30 years after operation to detect and treat nutritional deficiencies.RESULTS:By the end of the first decade iron deficiency was the commone...

journal_title：World journal of gastroenterology

authors： Tovey FI,Hobsley M

更新日期：2000-02-01 00:00:00

abstract：AIM:To estimate the effect of a therapeutic vaccine against pancreatic carcinoma based on dendritic cell (DC) vaccine modified with tumor lysate and Interleukin-18 gene. METHODS:The BALB/C mice model of pancreatic carcinoma was induced with DMBA. DC vaccine was constructed through pulsed with tumor lysate and transfec...

journal_title：World journal of gastroenterology

authors： Tang ZH,Qiu WH,Wu GS,Yang XP,Zou SQ,Qiu FZ

更新日期：2002-10-01 00:00:00

abstract：:We report a rare case of hypereosinophilic syndrome (HES) presenting with intractable gastric ulcers. A 71-year-old man was admitted with epigastric pain. Initial endoscopic findings revealed multiple, active gastric ulcers in the gastric antrum. He underwent Helicobacter pylori (H pylori) eradication therapy followed...

journal_title：World journal of gastroenterology

authors： Park TY,Choi CH,Yang SY,Oh IS,Song ID,Lee HW,Kim HJ,Do JH,Chang SK,Cho AR,Cha YJ

更新日期：2009-12-28 00:00:00

abstract：:The purpose of this article is to review the evidence regarding transmission of infection during gastrointestinal endoscopy, factors important in endoscope reprocessing and infection control, areas to focus on to improve compliance, and recent developments and advances in the field. ...

journal_title：World journal of gastroenterology

authors： Nelson DB,Muscarella LF

更新日期：2006-07-07 00:00:00

abstract：AIM:Single nucleotide polymorphisms (SNPs) of uridine-diphosphoglucuro-nosyltransferase 1A7 (UGT1A7) gene are associated with the development of orolaryngeal cancer, hepatocellular carcinoma, and colorectal cancer. We performed this research to establish the techniques for determining UGT1A7 gene and basic data of this...

journal_title：World journal of gastroenterology

authors： Huang MJ,Yang SS,Lin MS,Huang CS

更新日期：2005-02-14 00:00:00

abstract：AIM:To study the expression of vascular endothelial growth factor A (VEGF-A) and VEGF-C and to determine whether the presence of VEGF-A and VEGF-C was associated with the clinicopathologic characteristics of pancreatic cancer. METHODS:VEGF-A and VEGF-C mRNA transcripts were examined by Northern blot in 6 human pancrea...

journal_title：World journal of gastroenterology

authors： Tang RF,Wang SX,Peng L,Wang SX,Zhang M,Li ZF,Zhang ZM,Xiao Y,Zhang FR

更新日期：2006-01-14 00:00:00

abstract：AIM:To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice. METHODS:Balb/c mice were fed with the fermented milk for 7 d after inducing gastritis with acetyl-salicylic acid (ASA, 400 m...

journal_title：World journal of gastroenterology

authors： Rodríguez C,Medici M,Mozzi F,Font de Valdez G

更新日期：2010-04-07 00:00:00

abstract：:Pancreatic cancer is one of the most aggressive and difficult cancers to treat. Despite numerous research efforts, limited success has been achieved in the therapeutic management of patients with this disease. In the current review, we focus on one component of morphogenesis signaling, Hedgehog (Hh), with the aim of d...

journal_title：World journal of gastroenterology

authors： Onishi H,Katano M

更新日期：2014-03-07 00:00:00

abstract：:Synchronous occurrence of epithelial neoplasia and gastrointestinal stromal tumor (GIST) in the stomach is uncommon. Only rare cases have been reported in the literature. We present here a 60-year-old female case of synchronous occurrence of gastric high-level intraepithelial neoplasia and GIST with the features of 22...

journal_title：World journal of gastroenterology

authors： Mou YP,Xu XW,Xie K,Zhou W,Zhou YC,Chen K

更新日期：2010-10-21 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：AIM:To investigate the global gene expression of cancer related genes in hepatoma cell line HLE using Atlas Human Cancer Array membranes with 588 well-characterized human genes related with cancer and tumor biology. METHODS:Hybridization of cDNA blotting membrane was performed with (32)P-labeled cDNA probes synthesize...

journal_title：World journal of gastroenterology

authors： Liu LX,Liu ZH,Jiang HC,Zhang WH,Qi SY,Hu J,Wang XQ,Wu M

更新日期：2003-04-01 00:00:00

abstract：AIM:To explore the mechanism of protection against acetaminophen-induced acute liver injury by Liuweiwuling tablets. METHODS:Intraperitoneal injections of acetaminophen (250 mg/kg) were used to induce acute liver injury in male C57BL/6 mice. A total of 24 healthy mice were randomly assigned to two groups: an acute liv...

journal_title：World journal of gastroenterology

authors： Lei YC,Li W,Luo P

更新日期：2015-07-14 00:00:00

abstract：AIM:To investigate the relationship of changes in expression of marker genes in functional categories or molecular networks comprising one functional category or multiple categories in progression of hepatic fibrosis in hepatitis C (HCV) patients. METHODS:Marker genes were initially identified using DNA microarray dat...

journal_title：World journal of gastroenterology

authors： Takahara Y,Takahashi M,Zhang QW,Wagatsuma H,Mori M,Tamori A,Shiomi S,Nishiguchi S

更新日期：2008-04-07 00:00:00

abstract：AIM:To assess the safety of bismuth used in Helicobacter pylori (H pylori) eradication therapy regimens. METHODS:We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled trials comparing bismuth with placebo or no treatment, or bismuth ...

journal_title：World journal of gastroenterology

authors： Ford AC,Malfertheiner P,Giguere M,Santana J,Khan M,Moayyedi P

更新日期：2008-12-28 00:00:00

abstract：:A clinical trial of radiotherapy with modified simultaneous integrated boost (SIB) technique against huge tumors was conducted. A 58-year-old male patient who had a huge pelvic tumor diagnosed as a rectal adenocarcinoma due to familial adenomatous polyposis was enrolled in this trial. The total dose of 77 Gy (equivale...

journal_title：World journal of gastroenterology

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Kawashiro S,Hagiwara M,Chin M,Hashizume E,Nemoto K

更新日期：2014-12-28 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. The efficacy and safety profile of pharmacotherapy in the treatment of NAFLD remains uncertai...

journal_title：World journal of gastroenterology

authors： Zelber-Sagi S,Ratziu V,Oren R

更新日期：2011-08-07 00:00:00

abstract：:A 53-year-old male patient with a large hydatid cyst of the left hemidiaphragm and smaller secondary cysts located in the left thoracic cavity and upper left abdominal quadrant presented with two progressively enlarging lipoma-like masses in the left hypochondrium and under the left scapulae respectively. Total excisi...

journal_title：World journal of gastroenterology

authors： Marinis A,Fragulidis G,Karapanos K,Konstantinidis C,Brestas P,Vassiliou J,Smyrniotis V

更新日期：2006-11-28 00:00:00

abstract：AIM:To clarify the expression and role of Ephrin receptor A4 (EphA4) in gastric cancer in relation to clinicopathological characteristics and the expression of fibroblast growth factor receptor 1 (FGFR1) and ephrin ligands. METHODS:Eleven gastric carcinoma cell lines, 24 paired surgical fresh specimens of gastric aden...

journal_title：World journal of gastroenterology

authors： Oki M,Yamamoto H,Taniguchi H,Adachi Y,Imai K,Shinomura Y

更新日期：2008-10-07 00:00:00

abstract：AIM:To investigate the effect of Lactobacillus-containing commercially available probiotic formulations in Germany during antibiotic treatment with an analysis of cost-efficiency. METHODS:In an observational study, we analyzed the frequency of bowel movements from 258 patients with infections in a primary care hospita...

journal_title：World journal of gastroenterology

authors： Dietrich CG,Kottmann T,Alavi M

更新日期：2014-11-14 00:00:00

abstract：BACKGROUND:Given the shortage of suitable liver grafts for liver transplantation, proper use of hepatitis B core antibody-positive livers might be a possible way to enlarge the donor pool and to save patients with end-stage liver diseases. However, the safety of hepatitis B virus core antibody positive (HBcAb+) donors ...

journal_title：World journal of gastroenterology

authors： Lei M,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Wu H,Xu MQ,Chen ZY,Wei YG

更新日期：2018-12-28 00:00:00

abstract：AIM:To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS:We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tumours in nude mice. Th...

journal_title：World journal of gastroenterology

authors： Kunanopparat A,Issara-Amphorn J,Leelahavanichkul A,Sanpavat A,Patumraj S,Tangkijvanich P,Palaga T,Hirankarn N

更新日期：2018-09-14 00:00:00

abstract：AIM:To investigate the inhibitory effects of sinomenine (SIN) combined with 5-fluorouracil (5-FU) on esophageal carcinoma in vitro and in vivo. METHODS:Esophageal carcinoma (Eca-109) cells were cultured in DMEM. The single or combined growth inhibition effects of SIN and 5-FU on the Eca-109 cells were examined by meas...

journal_title：World journal of gastroenterology

authors： Wang J,Yang ZR,Dong WG,Zhang JX,Guo XF,Song J,Qiu S

更新日期：2013-12-07 00:00:00

abstract：AIM:To evaluate the diagnostic values of serum autoantibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoantibodies were then measur...

journal_title：World journal of gastroenterology

authors： Zhou JH,Zhang B,Kernstine KH,Zhong L

更新日期：2011-03-14 00:00:00

abstract：:Single-incision laparoscopic surgery (SILS) and natural orifice transluminal endoscopic surgery (NOTES) have rapidly gained pace worldwide, potentially replacing conventional laparoscopic surgery (CLS) as the preferred colorectal surgery technique. Currently available data mainly consist of retrospective series analyz...

journal_title：World journal of gastroenterology

authors： Daher R,Chouillard E,Panis Y

更新日期：2014-12-28 00:00:00

abstract：AIM:To investigate the role of reactive oxygen species (ROS) in ethanol-mediated cell death of polarized hepatic (WIF-B) cells. METHODS:In this work, WIF-B cultures were treated with pyrazole (inducer of cytochrome P4502E1, CYP2E1) and/or L-buthionine sulfoximine (BSO), a known inhibitor of hepatic glutathione (GSH), ...

journal_title：World journal of gastroenterology

authors： McVicker BL,Tuma PL,Kharbanda KK,Lee SM,Tuma DJ

更新日期：2009-06-07 00:00:00

abstract：AIM:To investigate the distribution pattern of lymphatic vessels and microvessels in sporadic colorectal carcinoma (SCRC) and their relationship to metastasis and prognosis. METHODS:The lymphatic vessel density (LVD) and microvessel density (MVD) in tumor tissue obtained from 132 patients with primary SCRC, including ...

journal_title：World journal of gastroenterology

authors： Yan G,Zhou XY,Cai SJ,Zhang GH,Peng JJ,Du X

更新日期：2008-01-07 00:00:00

abstract：AIM:Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS:Thirty lesions each of hyperdense, isodense and hypodense attenua...

journal_title：World journal of gastroenterology

authors： Veit P,Kuehle C,Beyer T,Kuehl H,Bockisch A,Antoch G

更新日期：2006-04-21 00:00:00

abstract：:Cancer patients have unique problems associated with hepatitis C virus (HCV) infection and treatment not seen in the general population. HCV infection poses additional challenges and considerations for the management of cancer, and vice versa. HCV infection also can lead to the development of cancer, particularly hepa...

journal_title：World journal of gastroenterology

authors： Borchardt RA,Torres HA

更新日期：2014-03-21 00:00:00

abstract：AIM:To study the dynamic changes of hepatitis B virus (HBV) DNA in serum and peripheral blood mononuclear cells (PBMCs) of patients after lamivudine therapy. METHODS:A total of 72 patients with chronic HBV infection were included in this study. All patients were confirmed to have the following conditions: above 16 yea...

journal_title：World journal of gastroenterology

authors： Ke CZ,Chen Y,Gong ZJ,Meng ZJ,Liu L,Ren ZJ,Zhou ZH

更新日期：2006-07-07 00:00:00