Prevalence of diverticulosis in recurrent Clostridium difficile infection.

Abstract:

AIM:To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse. METHODS:Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexible sigmoidoscopy. An age and gender matched control group was used to compare the prevalence of diverticulosis. RESULTS:Twenty-two patients met the study criteria, and the prevalence of diverticulosis in patients with CDAD relapse was 23% compared to 32% in age and sex matched controls (P = 0.44). A significant proportion of patients with CDAD relapse had co-morbidities associated with immune suppression. CONCLUSION:Diverticulosis does not appear to be associated with CDAD relapse.

journal_name

World J Gastroenterol

authors

Lipp MJ,Pagovich OE,Rabin D,Min AD,Bernstein BB

doi

10.3748/wjg.v16.i3.345

subject

Has Abstract

pub_date

2010-01-21 00:00:00

pages

345-7

issue

3

eissn

1007-9327

issn

2219-2840

journal_volume

16

pub_type

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